DK213983D0 - Fremgangsmade til fremstilling af humant insulin eller b30-estere deraf - Google Patents

Fremgangsmade til fremstilling af humant insulin eller b30-estere deraf

Info

Publication number
DK213983D0
DK213983D0 DK2139/83A DK213983A DK213983D0 DK 213983 D0 DK213983 D0 DK 213983D0 DK 2139/83 A DK2139/83 A DK 2139/83A DK 213983 A DK213983 A DK 213983A DK 213983 D0 DK213983 D0 DK 213983D0
Authority
DK
Denmark
Prior art keywords
esters
human insulin
preparing human
preparing
insulin
Prior art date
Application number
DK2139/83A
Other languages
English (en)
Other versions
DK149457B (da
DK149457C (da
DK213983A (da
Inventor
Finn Hede Andresen
Per Balschmidt
Kim Ry Hejnaes
Hans Kofod
Original Assignee
Nordisk Insulinlab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Insulinlab filed Critical Nordisk Insulinlab
Publication of DK213983A publication Critical patent/DK213983A/da
Publication of DK213983D0 publication Critical patent/DK213983D0/da
Publication of DK149457B publication Critical patent/DK149457B/da
Application granted granted Critical
Publication of DK149457C publication Critical patent/DK149457C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK213983A 1982-06-07 1983-05-13 Fremgangsmaade til fremstilling af humant insulin eller b30-estere deraf DK149457C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK254582 1982-06-07
DK254582 1982-06-07
DK254682 1982-06-07
DK254682 1982-06-07
DK8200082 1982-09-14
PCT/DK1982/000082 WO1983001074A1 (en) 1981-09-15 1982-09-14 Enzymatic preparation of human insulin or b-30 esters thereof

Publications (4)

Publication Number Publication Date
DK213983A DK213983A (da) 1983-05-13
DK213983D0 true DK213983D0 (da) 1983-05-13
DK149457B DK149457B (da) 1986-06-16
DK149457C DK149457C (da) 1991-11-25

Family

ID=26066590

Family Applications (1)

Application Number Title Priority Date Filing Date
DK213983A DK149457C (da) 1982-06-07 1983-05-13 Fremgangsmaade til fremstilling af humant insulin eller b30-estere deraf

Country Status (11)

Country Link
US (1) US4601979A (da)
EP (1) EP0088117B1 (da)
JP (1) JPS58501455A (da)
AU (1) AU551174B2 (da)
CA (1) CA1174623A (da)
DK (1) DK149457C (da)
ES (1) ES515713A0 (da)
FI (1) FI78119C (da)
IT (1) IT1189353B (da)
NO (1) NO156052C (da)
WO (1) WO1983001074A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0092829B1 (en) * 1982-04-23 1990-11-07 Wako Pure Chemical Industries, Ltd. Process for semi-synthesis of human insulin and alkaline protease for use therein
EP0294851A3 (de) * 1987-06-12 1990-05-09 Berlin-Chemie Ag Verfahren zur Herstellung von Humaninsulin und seinen Derivaten
US5130236A (en) * 1989-12-07 1992-07-14 Eli Lilly And Company Process for producing des(64,65)-proinsulin
JP2001521004A (ja) 1997-10-24 2001-11-06 イーライ・リリー・アンド・カンパニー 脂肪酸−アシル化インスリン類似体
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
US6323311B1 (en) 1999-09-22 2001-11-27 University Of Utah Research Foundation Synthesis of insulin derivatives
US7396903B2 (en) * 2001-11-19 2008-07-08 Novo Nordisk A/S Process for preparing insulin compounds
RU2376379C2 (ru) 2001-11-19 2009-12-20 Ново Нордиск А/С Способ получения инсулиновых соединений
US8173840B2 (en) * 2003-07-29 2012-05-08 Signature R&D Holdings, Llc Compounds with high therapeutic index
US7589233B2 (en) * 2003-07-29 2009-09-15 Signature R&D Holdings, Llc L-Threonine derivatives of high therapeutic index
CN105849273B (zh) * 2013-12-23 2020-01-14 拜康研究有限公司 人胰岛素甲酯的生产方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
WO1980002157A1 (en) * 1979-04-06 1980-10-16 Forenede Bryggerier As A process for enzymatic production of peptides
NO153061C (no) * 1979-04-13 1986-01-08 Shionogi & Co Fremgangsmaate for fremstilling av et b30-threonininsulin
JPS55138392A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"

Also Published As

Publication number Publication date
FI831157A0 (fi) 1983-04-06
IT8249114A1 (it) 1984-03-14
AU8953982A (en) 1983-04-08
CA1174623A (en) 1984-09-18
NO156052B (no) 1987-04-06
NO831730L (no) 1983-05-13
AU551174B2 (en) 1986-04-17
ES8400772A1 (es) 1983-11-01
ES515713A0 (es) 1983-11-01
DK149457B (da) 1986-06-16
IT1189353B (it) 1988-02-04
FI831157L (fi) 1983-04-06
FI78119C (fi) 1989-06-12
NO156052C (no) 1987-07-15
FI78119B (fi) 1989-02-28
JPS58501455A (ja) 1983-09-01
JPH0526469B2 (da) 1993-04-16
DK149457C (da) 1991-11-25
DK213983A (da) 1983-05-13
EP0088117B1 (en) 1986-09-24
WO1983001074A1 (en) 1983-03-31
US4601979A (en) 1986-07-22
IT8249114A0 (it) 1982-09-14
EP0088117A1 (en) 1983-09-14

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Legal Events

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PBP Patent lapsed