DK214585A - Fremgangsmaade til fremstilling af imidazorifamyciner - Google Patents

Fremgangsmaade til fremstilling af imidazorifamyciner Download PDF

Info

Publication number: DK214585A
Authority: DK; Denmark
Prior art keywords: alkyl; formula; image; carbamoyl; mono
Prior art date: 1984-05-15

Application number

DK214585A

Other languages

English (en)

Other versions

DK160829B (da

DK160829C (da

DK214585D0 (da

Inventor

Vincenzo Cannata

Silvano Piani

Gian Franco Tamagnone

Manuela Campana

Giovanni Da Roit

Original Assignee

Alfa Farmaceutici Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-05-15

Filing date

1985-05-14

Publication date

1985-11-16

1984-05-15 Priority claimed from IT03465/84A external-priority patent/IT1199376B/it

1984-05-15 Priority claimed from IT03464/84A external-priority patent/IT1199375B/it

1985-05-14 Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa

1985-05-14 Publication of DK214585D0 publication Critical patent/DK214585D0/da

1985-11-16 Publication of DK214585A publication Critical patent/DK214585A/da

1991-04-22 Publication of DK160829B publication Critical patent/DK160829B/da

1991-10-07 Application granted granted Critical

1991-10-07 Publication of DK160829C publication Critical patent/DK160829C/da

Links

238000000034 method Methods 0.000 title abstract 2
-1 nitro, mercapto Chemical class 0.000 abstract 3
ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
BTVYFIMKUHNOBZ-ZDHWWVNNSA-N Rifamycin S Natural products COC1C=COC2(C)Oc3c(C)c(O)c4C(=O)C(=CC(=O)c4c3C2=O)NC(=O)C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(=O)C)C1C)C BTVYFIMKUHNOBZ-ZDHWWVNNSA-N 0.000 abstract 1
BTVYFIMKUHNOBZ-ODRIEIDWSA-N Rifamycin S Chemical compound O=C1C(C(O)=C2C)=C3C(=O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O BTVYFIMKUHNOBZ-ODRIEIDWSA-N 0.000 abstract 1
125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003222 pyridines Chemical class 0.000 abstract 1

Landscapes

Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK214585A 1984-05-15 1985-05-14 Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner DK160829C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
IT346484		1984-05-15
IT03465/84A IT1199376B (it)	1984-05-15	1984-05-15	Processo per la preparazione di imidazo-rifamicine
IT03464/84A IT1199375B (it)	1984-05-15	1984-05-15	Processo per la preparazione di imidazo rifamicine
IT346584		1984-05-15

Publications (4)

Publication Number	Publication Date
DK214585D0 DK214585D0 (da)	1985-05-14
DK214585A true DK214585A (da)	1985-11-16
DK160829B DK160829B (da)	1991-04-22
DK160829C DK160829C (da)	1991-10-07

Family

ID=26325399

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK214585A DK160829C (da)	1984-05-15	1985-05-14	Fremgangsmaade til fremstilling af pyrido-imidazorifamyciner

Country Status (9)

Country	Link
AR (1)	AR242795A1 (da)
AT (1)	AT386829B (da)
CA (1)	CA1215976A (da)
DK (1)	DK160829C (da)
ES (1)	ES543116A0 (da)
FI (1)	FI83874C (da)
GR (1)	GR851146B (da)
NO (1)	NO164030C (da)
PT (1)	PT80447B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7902206B2 (en)	2003-11-07	2011-03-08	Alfa Wassermann, S.P.A.	Polymorphic forms α, β and γ of rifaximin
US7906542B2 (en)	2004-11-04	2011-03-15	Alfa Wassermann, S.P.A.	Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
ITMI20032144A1 (it)	2003-11-07	2005-05-08	Alfa Wassermann Spa	Forme polimorfe di rifaximina, processi per ottenerle e
PT1698630E (pt)	2005-03-03	2014-09-15	Alfa Wassermann Spa	Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais
WO2008035109A1 (en)	2006-09-22	2008-03-27	Cipla Limited	Rifaximin
US7709634B2 (en)	2007-09-20	2010-05-04	Apotex Pharmachem Inc.	Amorphous form of rifaximin and processes for its preparation
KR101906177B1 (ko)	2008-12-10	2018-10-10	시플라 리미티드	리팍시민 복합체
ITBO20120368A1 (it)	2012-07-06	2014-01-07	Alfa Wassermann Spa	Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
ES2621557T3 (es)	2014-03-31	2017-07-04	Euticals S.P.A.	Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
EP3134415A4 (en) *	2014-04-19	2017-10-25	Granules India Limited	An improved process for the preparation of rifamycin derivatives
DK3546464T3 (da)	2014-05-12	2020-07-27	Alfasigma Spa	Fremstilling og anvendelse af den krystallinske form tau af rifaximin solvateret med degme

1985
- 1985-04-29 CA CA000480320A patent/CA1215976A/en not_active Expired
- 1985-05-13 GR GR851146A patent/GR851146B/el unknown
- 1985-05-13 PT PT8044785A patent/PT80447B/pt unknown
- 1985-05-14 NO NO851920A patent/NO164030C/no unknown
- 1985-05-14 DK DK214585A patent/DK160829C/da not_active IP Right Cessation
- 1985-05-14 AT AT145085A patent/AT386829B/de not_active IP Right Cessation
- 1985-05-14 FI FI851908A patent/FI83874C/fi not_active IP Right Cessation
- 1985-05-14 ES ES543116A patent/ES543116A0/es active Granted
- 1985-05-15 AR AR30038685A patent/AR242795A1/es active

Also Published As

Publication number	Publication date
ES8603490A1 (es)	1986-01-01
PT80447A (en)	1985-06-01
CA1215976A (en)	1986-12-30
ATA145085A (de)	1988-03-15
ES543116A0 (es)	1986-01-01
NO164030B (no)	1990-05-14
GR851146B (da)	1985-11-25
FI851908L (fi)	1985-11-16
PT80447B (pt)	1987-11-11
FI851908A0 (fi)	1985-05-14
DK160829B (da)	1991-04-22
AT386829B (de)	1988-10-25
FI83874B (fi)	1991-05-31
DK160829C (da)	1991-10-07
NO164030C (no)	1990-08-22
DK214585D0 (da)	1985-05-14
NO851920L (no)	1985-11-18
FI83874C (fi)	1991-09-10
AR242795A1 (es)	1993-05-31

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Legal Events

Date	Code	Title	Description
1998-01-19	PBP	Patent lapsed