DK434985A - Fremgangsmaade til fremstilling af pyrido-imidazo-rifamyciner - Google Patents

Fremgangsmaade til fremstilling af pyrido-imidazo-rifamyciner Download PDF

Info

Publication number: DK434985A
Authority: DK; Denmark
Prior art keywords: alkyl; mono; rifamycines; imidazo; hydrogen
Prior art date: 1984-09-26

Application number

DK434985A

Other languages

English (en)

Other versions

DK161706C (da

DK161706B (da

DK434985D0 (da

Inventor

Vicenzo Cannata

Gian Franco Tamagnone

Manuela Campana

Silvano Piani

Raul Roberto Alpino

Original Assignee

Alfa Farmaceutici Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-09-26

Filing date

1985-09-25

Publication date

1986-03-27

1985-09-25 Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa

1985-09-25 Publication of DK434985D0 publication Critical patent/DK434985D0/da

1986-03-27 Publication of DK434985A publication Critical patent/DK434985A/da

1991-08-05 Publication of DK161706B publication Critical patent/DK161706B/da

1992-01-20 Application granted granted Critical

1992-01-20 Publication of DK161706C publication Critical patent/DK161706C/da

Links

-1 hydroxy-(C2-4)-alkyl Chemical group 0.000 abstract 4
ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000007800 oxidant agent Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003222 pyridines Chemical class 0.000 abstract 1
SQTCRTQCPJICLD-KTQDUKAHSA-N rifamycin B Chemical compound OC1=C(C(O)=C2C)C3=C(OCC(O)=O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O SQTCRTQCPJICLD-KTQDUKAHSA-N 0.000 abstract 1
SQTCRTQCPJICLD-OQQFTUDCSA-N rifomycin-B Natural products COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(=O)C)C1C)C)cc(OCC(=O)O)c4c3C2=O SQTCRTQCPJICLD-OQQFTUDCSA-N 0.000 abstract 1
239000007858 starting material Substances 0.000 abstract 1

Landscapes

Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK434985A 1984-09-26 1985-09-25 Fremgangsmaade til fremstilling af pyrido-imidazo-rifamyciner DK161706C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT03581/84A IT1199413B (it)	1984-09-26	1984-09-26	Processo per la preparazione di pirido-imidazo-rifamicine
IT358184		1984-09-26

Publications (4)

Publication Number	Publication Date
DK434985D0 DK434985D0 (da)	1985-09-25
DK434985A true DK434985A (da)	1986-03-27
DK161706B DK161706B (da)	1991-08-05
DK161706C DK161706C (da)	1992-01-20

Family

ID=11110114

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK434985A DK161706C (da)	1984-09-26	1985-09-25	Fremgangsmaade til fremstilling af pyrido-imidazo-rifamyciner

Country Status (10)

Country	Link
AR (1)	AR243892A1 (da)
AT (1)	AT387020B (da)
CA (1)	CA1218650A (da)
DK (1)	DK161706C (da)
ES (1)	ES8604735A1 (da)
FI (1)	FI83875C (da)
GR (1)	GR852312B (da)
IT (1)	IT1199413B (da)
NO (1)	NO165107C (da)
PT (1)	PT81198B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7902206B2 (en)	2003-11-07	2011-03-08	Alfa Wassermann, S.P.A.	Polymorphic forms α, β and γ of rifaximin
ITMI20032144A1 (it)	2003-11-07	2005-05-08	Alfa Wassermann Spa	Forme polimorfe di rifaximina, processi per ottenerle e
US7906542B2 (en)	2004-11-04	2011-03-15	Alfa Wassermann, S.P.A.	Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
SI1698630T1 (sl)	2005-03-03	2015-01-30	Alfa Wassermann S.P.A.	Nove polimorfne oblike rifaksimina, postopki za njihovo pripravo in njihova uporaba v medicinskih pripravkih
US7709634B2 (en)	2007-09-20	2010-05-04	Apotex Pharmachem Inc.	Amorphous form of rifaximin and processes for its preparation
ITBO20120368A1 (it)	2012-07-06	2014-01-07	Alfa Wassermann Spa	Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
ES2621557T3 (es)	2014-03-31	2017-07-04	Euticals S.P.A.	Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
PT3546464T (pt)	2014-05-12	2020-08-05	Alfasigma Spa	Preparação e utilização da forma cristalina tau de rifaximina solvatada com degme

1984
- 1984-09-26 IT IT03581/84A patent/IT1199413B/it active
1985
- 1985-09-23 GR GR852312A patent/GR852312B/el unknown
- 1985-09-25 CA CA000491511A patent/CA1218650A/en not_active Expired
- 1985-09-25 FI FI853683A patent/FI83875C/fi not_active IP Right Cessation
- 1985-09-25 NO NO853771A patent/NO165107C/no unknown
- 1985-09-25 AT AT279785A patent/AT387020B/de not_active IP Right Cessation
- 1985-09-25 ES ES547265A patent/ES8604735A1/es not_active Expired
- 1985-09-25 DK DK434985A patent/DK161706C/da not_active IP Right Cessation
- 1985-09-26 PT PT8119885A patent/PT81198B/pt unknown
- 1985-09-26 AR AR30174785A patent/AR243892A1/es active

Also Published As

Publication number	Publication date
DK161706C (da)	1992-01-20
NO853771L (no)	1986-04-01
DK161706B (da)	1991-08-05
AT387020B (de)	1988-11-25
FI83875C (fi)	1991-09-10
NO165107C (no)	1990-12-27
IT8403581A0 (it)	1984-09-26
AR243892A1 (es)	1993-09-30
DK434985D0 (da)	1985-09-25
ES547265A0 (es)	1986-02-16
PT81198B (pt)	1987-09-30
NO165107B (no)	1990-09-17
FI853683L (fi)	1986-03-27
FI853683A0 (fi)	1985-09-25
FI83875B (fi)	1991-05-31
ES8604735A1 (es)	1986-02-16
CA1218650A (en)	1987-03-03
PT81198A (en)	1985-10-01
ATA279785A (de)	1988-04-15
IT1199413B (it)	1988-12-30
GR852312B (da)	1986-01-24

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Legal Events

Date	Code	Title	Description
1998-05-11	PBP	Patent lapsed