DK2155228T3 - Polypeptidinhibitorer af HSP27-kinase og anvendelser herfor - Google Patents
Polypeptidinhibitorer af HSP27-kinase og anvendelser herforInfo
- Publication number
- DK2155228T3 DK2155228T3 DK07836118.5T DK07836118T DK2155228T3 DK 2155228 T3 DK2155228 T3 DK 2155228T3 DK 07836118 T DK07836118 T DK 07836118T DK 2155228 T3 DK2155228 T3 DK 2155228T3
- Authority
- DK
- Denmark
- Prior art keywords
- applications
- kinase polypeptide
- polypeptide inhibitors
- hsp27 kinase
- hsp27
- Prior art date
Links
- 108010041955 MAP-kinase-activated kinase 2 Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88013707P | 2007-01-10 | 2007-01-10 | |
| PCT/US2007/016246 WO2008085191A1 (en) | 2007-01-10 | 2007-07-16 | Polypeptide inhibitors of hsp27 kinase and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2155228T3 true DK2155228T3 (da) | 2014-07-07 |
Family
ID=39608928
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13001411.1T DK2617431T3 (da) | 2007-01-10 | 2007-07-16 | Polypeptidinhibitorer af HSP27-kinase og anvendelser derfor |
| DK07836118.5T DK2155228T3 (da) | 2007-01-10 | 2007-07-16 | Polypeptidinhibitorer af HSP27-kinase og anvendelser herfor |
| DK13001412.9T DK2606903T3 (da) | 2007-01-10 | 2007-07-16 | Polypeptidinhibitorer af HSP27-kinase og anvendelser herfor |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13001411.1T DK2617431T3 (da) | 2007-01-10 | 2007-07-16 | Polypeptidinhibitorer af HSP27-kinase og anvendelser derfor |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13001412.9T DK2606903T3 (da) | 2007-01-10 | 2007-07-16 | Polypeptidinhibitorer af HSP27-kinase og anvendelser herfor |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8536303B2 (da) |
| EP (3) | EP2606903B1 (da) |
| AU (1) | AU2007342674B2 (da) |
| CA (2) | CA2898230C (da) |
| DK (3) | DK2617431T3 (da) |
| ES (3) | ES2476842T3 (da) |
| WO (1) | WO2008085191A1 (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080293640A1 (en) * | 2007-01-10 | 2008-11-27 | Arizona Board of Regents, A body Corporate, of the State of Arizona, acting for and on behalf of | Polypeptide inhibitors of HSP27 kinase and uses therefor |
| AU2007342674B2 (en) | 2007-01-10 | 2013-09-19 | Purdue Research Foundation | Polypeptide inhibitors of HSP27 kinase and uses therefor |
| JP5703466B2 (ja) | 2007-08-07 | 2015-04-22 | パーデュー・リサーチ・ファウンデーションPurdue Research Foundation | キナーゼ阻害薬およびその使用 |
| MX340916B (es) | 2008-01-18 | 2016-07-29 | President And Fellows Of Harvard College * | Metodos para detectar señales de identificacion de enfermedad o condiciones en fluidos corporales. |
| CN102256613B (zh) * | 2008-10-20 | 2014-09-10 | 莫伊莱麦屈克斯公司 | 用于治疗或者预防粘连的多肽 |
| CA2744104C (en) | 2008-12-10 | 2017-07-18 | Purdue Research Foundation | Cell-permeant peptide-based inhibitor of kinases |
| AU2013202108B2 (en) * | 2008-12-10 | 2015-12-24 | Purdue Research Foundation | Cell-permeant peptide-based inhibitor of kinases |
| US9890195B2 (en) * | 2009-07-27 | 2018-02-13 | Purdue Research Foundation | MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration |
| US20130115256A1 (en) * | 2010-05-24 | 2013-05-09 | Cynthia Lander | Methods for treating or preventing vascular graft failure |
| US20130203624A1 (en) | 2010-07-23 | 2013-08-08 | President And Fellows Of Harvard College | Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions |
| TW201209171A (en) | 2010-07-23 | 2012-03-01 | Harvard College | Methods of detecting diseases or conditions using phagocytic cells |
| EP2596132A4 (en) | 2010-07-23 | 2013-12-18 | Harvard College | METHOD FOR DETECTING SIGNS FOR ILLNESS OR SUFFERING IN BODY FLUIDS |
| AU2011280997A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
| US9890200B2 (en) * | 2011-04-12 | 2018-02-13 | Moerae Matrix, Inc. | Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition |
| BR112013026313A8 (pt) | 2011-04-12 | 2018-01-30 | Moerae Matrix Inc | composições e métodos para prevenir ou tratar doenças, condições ou processos caracterizados por proliferação anormal de fibroblastos e depósito de matriz extracelular |
| CA2747509C (en) | 2011-05-12 | 2017-07-18 | Oncogenex Technologies Inc. | Treatment of pulmonary and pleural fibrosis using hsp27 inhibitors |
| WO2013134636A1 (en) | 2012-03-09 | 2013-09-12 | Purdue Research Foundation | Compositions and methods for delivery of kinase inhibiting peptides |
| US20140072613A1 (en) * | 2012-09-10 | 2014-03-13 | Cynthia Lander | Compositions and Methods for Treating Cutaneous Scarring |
| WO2014164362A1 (en) | 2013-03-09 | 2014-10-09 | Harry Stylli | Methods of detecting prostate cancer |
| NZ771629A (en) | 2013-03-09 | 2022-12-23 | Harry Stylli | Methods of detecting cancer |
| US10336788B2 (en) * | 2014-04-17 | 2019-07-02 | Moerae Matrix, Inc. | Inhibition of cardiac fibrosis in myocardial infarction |
| US10626464B2 (en) | 2014-09-11 | 2020-04-21 | Cell Mdx, Llc | Methods of detecting prostate cancer |
| CN107106650A (zh) * | 2014-11-17 | 2017-08-29 | 莫伊莱麦屈克斯公司 | 用于预防或治疗表征为异常的成纤维细胞增殖和细胞外基质沉积的疾病、状况或过程的组合物和方法 |
| EP3242886A4 (en) | 2015-01-08 | 2018-08-29 | Moerae Matrix, Inc., | Formulation of mk2 inhibitor peptides |
| JP2018512401A (ja) * | 2015-03-12 | 2018-05-17 | モイライ マトリックス インコーポレイテッド | Mk2阻害剤ペプチド含有組成物を用いた非小細胞肺癌の治療を目的とするその使用 |
| US11946927B2 (en) | 2016-03-14 | 2024-04-02 | Musidora Biotechnology Llc | Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment |
| US10295527B2 (en) | 2016-03-14 | 2019-05-21 | Bruce Yacyshyn | Process and system for predicting responders and non-responders to mesalamine treatment of ulcerative colitis |
| CN111163784B (zh) * | 2017-09-01 | 2024-07-26 | 黄玲惠 | 用于治疗蟹足肿的药物组合物及其用途 |
| CN115851946B (zh) * | 2022-11-24 | 2023-09-01 | 中山大学孙逸仙纪念医院 | CaMK I作为治疗靶点在制备胰腺癌治疗药物中的应用 |
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| WO2002057413A2 (en) * | 2001-01-18 | 2002-07-25 | The Board Of Trustees Of The Leland Stanford Junior University | Peptides for activation and inhibition of delta pkc |
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| US8008093B2 (en) * | 2004-12-02 | 2011-08-30 | The University Of North Carolina At Chapel Hill | Inhibition of Hsp27 phosphorylation for the treatment of blistering disorders |
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| EP1948259B1 (en) * | 2005-10-26 | 2017-03-22 | Genesis Technologies Limited | Acellular bioabsorbable tissue regeneration matrices produced by incubating acellular blood products |
| CA2626868A1 (en) * | 2005-11-01 | 2007-05-10 | The Arizona Board Of Regents, A Body Corporate Acting On Behalf Of Arizo Na State University | Novel protein transduction domains and uses therefor |
| WO2007062060A2 (en) * | 2005-11-22 | 2007-05-31 | Ted Reid | Methods and compositions using substance p to promote wound healing |
| EP2051727A4 (en) | 2006-07-12 | 2012-03-14 | Univ Arizona | METHOD FOR THE TREATMENT OF FIBROTIC DISEASES AND KELOIDS |
| US20080293640A1 (en) * | 2007-01-10 | 2008-11-27 | Arizona Board of Regents, A body Corporate, of the State of Arizona, acting for and on behalf of | Polypeptide inhibitors of HSP27 kinase and uses therefor |
| AU2007342674B2 (en) * | 2007-01-10 | 2013-09-19 | Purdue Research Foundation | Polypeptide inhibitors of HSP27 kinase and uses therefor |
| JP5703466B2 (ja) * | 2007-08-07 | 2015-04-22 | パーデュー・リサーチ・ファウンデーションPurdue Research Foundation | キナーゼ阻害薬およびその使用 |
| WO2009123759A2 (en) | 2008-04-02 | 2009-10-08 | Moerae Matrix, Inc. | Therapeutic uses of biocompatible biogel compositions |
| CN102256613B (zh) * | 2008-10-20 | 2014-09-10 | 莫伊莱麦屈克斯公司 | 用于治疗或者预防粘连的多肽 |
| CA2744104C (en) * | 2008-12-10 | 2017-07-18 | Purdue Research Foundation | Cell-permeant peptide-based inhibitor of kinases |
| US9890195B2 (en) * | 2009-07-27 | 2018-02-13 | Purdue Research Foundation | MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration |
| US20130115256A1 (en) * | 2010-05-24 | 2013-05-09 | Cynthia Lander | Methods for treating or preventing vascular graft failure |
| BR112013026313A8 (pt) | 2011-04-12 | 2018-01-30 | Moerae Matrix Inc | composições e métodos para prevenir ou tratar doenças, condições ou processos caracterizados por proliferação anormal de fibroblastos e depósito de matriz extracelular |
-
2007
- 2007-07-16 AU AU2007342674A patent/AU2007342674B2/en not_active Ceased
- 2007-07-16 DK DK13001411.1T patent/DK2617431T3/da active
- 2007-07-16 CA CA2898230A patent/CA2898230C/en not_active Expired - Fee Related
- 2007-07-16 WO PCT/US2007/016246 patent/WO2008085191A1/en not_active Ceased
- 2007-07-16 CA CA2689296A patent/CA2689296C/en not_active Expired - Fee Related
- 2007-07-16 ES ES07836118.5T patent/ES2476842T3/es active Active
- 2007-07-16 EP EP13001412.9A patent/EP2606903B1/en not_active Not-in-force
- 2007-07-16 EP EP13001411.1A patent/EP2617431B1/en not_active Not-in-force
- 2007-07-16 DK DK07836118.5T patent/DK2155228T3/da active
- 2007-07-16 DK DK13001412.9T patent/DK2606903T3/da active
- 2007-07-16 ES ES13001412.9T patent/ES2594281T3/es active Active
- 2007-07-16 ES ES13001411.1T patent/ES2624196T3/es active Active
- 2007-07-16 EP EP07836118.5A patent/EP2155228B1/en not_active Not-in-force
-
2008
- 2008-01-10 US US11/972,459 patent/US8536303B2/en active Active
-
2013
- 2013-07-03 US US13/934,933 patent/US9493508B2/en active Active
-
2016
- 2016-09-29 US US15/280,722 patent/US9649354B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20140112947A1 (en) | 2014-04-24 |
| US20170072009A1 (en) | 2017-03-16 |
| ES2594281T3 (es) | 2016-12-19 |
| EP2617431A2 (en) | 2013-07-24 |
| US20090196927A1 (en) | 2009-08-06 |
| EP2155228B1 (en) | 2014-04-02 |
| DK2606903T3 (da) | 2016-12-05 |
| US8536303B2 (en) | 2013-09-17 |
| ES2624196T3 (es) | 2017-07-13 |
| EP2606903A1 (en) | 2013-06-26 |
| CA2898230C (en) | 2018-04-24 |
| ES2476842T3 (es) | 2014-07-15 |
| EP2606903B1 (en) | 2016-09-14 |
| US9493508B2 (en) | 2016-11-15 |
| CA2689296C (en) | 2015-11-17 |
| EP2155228A1 (en) | 2010-02-24 |
| EP2617431A3 (en) | 2013-12-11 |
| AU2007342674B2 (en) | 2013-09-19 |
| AU2007342674A1 (en) | 2008-07-17 |
| US9649354B2 (en) | 2017-05-16 |
| CA2689296A1 (en) | 2008-07-17 |
| EP2155228A4 (en) | 2010-06-16 |
| WO2008085191A1 (en) | 2008-07-17 |
| EP2617431B1 (en) | 2017-04-12 |
| CA2898230A1 (en) | 2008-07-17 |
| DK2617431T3 (da) | 2017-07-10 |
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