DK2155254T3 - Med platinlægemidler konjugerede polymere - Google Patents

Med platinlægemidler konjugerede polymere

Info

Publication number
DK2155254T3
DK2155254T3 DK08769347.9T DK08769347T DK2155254T3 DK 2155254 T3 DK2155254 T3 DK 2155254T3 DK 08769347 T DK08769347 T DK 08769347T DK 2155254 T3 DK2155254 T3 DK 2155254T3
Authority
DK
Denmark
Prior art keywords
polymer conjugated
platinum drugs
platinum
drugs
conjugated
Prior art date
Application number
DK08769347.9T
Other languages
English (en)
Inventor
Sang Van
Gang Zhao
Lei Yu
Original Assignee
Nitto Denko Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Denko Corp filed Critical Nitto Denko Corp
Application granted granted Critical
Publication of DK2155254T3 publication Critical patent/DK2155254T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A61K49/146—Peptides, e.g. proteins the peptide being a polyamino acid, e.g. poly-lysine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyamides (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK08769347.9T 2007-05-09 2008-05-08 Med platinlægemidler konjugerede polymere DK2155254T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91685707P 2007-05-09 2007-05-09
PCT/US2008/063128 WO2008141111A2 (en) 2007-05-09 2008-05-08 Polymers conjugated with platinum drugs

Publications (1)

Publication Number Publication Date
DK2155254T3 true DK2155254T3 (da) 2013-03-04

Family

ID=39615788

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08769347.9T DK2155254T3 (da) 2007-05-09 2008-05-08 Med platinlægemidler konjugerede polymere

Country Status (7)

Country Link
US (1) US20080279782A1 (da)
EP (1) EP2155254B1 (da)
JP (1) JP2010528122A (da)
CN (1) CN101730549B (da)
DK (1) DK2155254T3 (da)
TW (1) TW200906440A (da)
WO (1) WO2008141111A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393315B2 (en) 2011-06-08 2016-07-19 Nitto Denko Corporation Compounds for targeting drug delivery and enhancing siRNA activity
EP2077290B1 (en) 2005-12-05 2010-04-21 Nitto Denko Corporation Polyglutamate-amino acid conjugates and methods
ES2430380T3 (es) * 2007-05-09 2013-11-20 Nitto Denko Corporation Composiciones que incluyen un compuesto hidrófobo y un conjugado de poliaminoácido
EP2155253A2 (en) * 2007-05-09 2010-02-24 Nitto Denko Corporation Polyglutamate conjugates and polyglutamate-amino acid conjugates having a plurality of drugs
KR20110074583A (ko) * 2008-10-15 2011-06-30 닛토덴코 가부시키가이샤 폴리글루타메이트 접합체의 제조 방법
EP2391630A2 (en) * 2009-01-31 2011-12-07 IGF Oncology, LLC Anti-cancer protein-platinum conjugates
JP2013514443A (ja) * 2009-12-16 2013-04-25 日東電工株式会社 ポリグルタミン酸の制御された合成
US10196637B2 (en) 2011-06-08 2019-02-05 Nitto Denko Corporation Retinoid-lipid drug carrier
US9884123B2 (en) 2012-01-03 2018-02-06 Invictus Oncology Pvt. Ltd. Ligand-targeted molecules and methods thereof
WO2013154707A1 (en) 2012-04-12 2013-10-17 Nitto Denko Corporation Co-polymer conjugates
CN104736179B (zh) 2012-05-07 2017-09-26 日东电工株式会社 具有接头的聚合物缀合物

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Also Published As

Publication number Publication date
EP2155254B1 (en) 2012-11-28
CN101730549A (zh) 2010-06-09
EP2155254A2 (en) 2010-02-24
WO2008141111A2 (en) 2008-11-20
HK1141462A1 (en) 2010-11-12
WO2008141111A3 (en) 2009-06-04
TW200906440A (en) 2009-02-16
US20080279782A1 (en) 2008-11-13
CN101730549B (zh) 2015-12-09
JP2010528122A (ja) 2010-08-19

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