DK2170877T5 - Substituerede (oxazolidinon-5-yl-methyl)-2-thiophen-carboxamider og anvendelsen heraf på området for koagulering - Google Patents

Substituerede (oxazolidinon-5-yl-methyl)-2-thiophen-carboxamider og anvendelsen heraf på området for koagulering

Info

Publication number
DK2170877T5
DK2170877T5 DK08773372.1T DK08773372T DK2170877T5 DK 2170877 T5 DK2170877 T5 DK 2170877T5 DK 08773372 T DK08773372 T DK 08773372T DK 2170877 T5 DK2170877 T5 DK 2170877T5
Authority
DK
Denmark
Prior art keywords
oxazolidinon
coagulation
substituted
methyl
field
Prior art date
Application number
DK08773372.1T
Other languages
English (en)
Other versions
DK2170877T3 (da
Inventor
Joachim Krueger
Susanne Roehrig
Holger Paulsen
Swen Allerheiligen
Stefan Heitmeier
Mark Jean Gnoth
Ulrich Rester
Elke Dittrich-Wengenroth
Uwe Saatmann
Adrian Tersteegen
Marcus Bauser
Dirk Heimbach
Christoph Gerdes
Degenfeld Georges Von
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39731148&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2170877(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of DK2170877T3 publication Critical patent/DK2170877T3/da
Application granted granted Critical
Publication of DK2170877T5 publication Critical patent/DK2170877T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DK08773372.1T 2007-06-20 2008-06-07 Substituerede (oxazolidinon-5-yl-methyl)-2-thiophen-carboxamider og anvendelsen heraf på området for koagulering DK2170877T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007028319A DE102007028319A1 (de) 2007-06-20 2007-06-20 Substituierte Oxazolidinone und ihre Verwendung
PCT/EP2008/004562 WO2008155032A1 (de) 2007-06-20 2008-06-07 Substituierte (oxazolidinon-5-yl-methyl) -2-thiophen-carboxamide und ihre verwendung im gebiet der blutgerinnung

Publications (2)

Publication Number Publication Date
DK2170877T3 DK2170877T3 (da) 2013-02-11
DK2170877T5 true DK2170877T5 (da) 2013-03-04

Family

ID=39731148

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08773372.1T DK2170877T5 (da) 2007-06-20 2008-06-07 Substituerede (oxazolidinon-5-yl-methyl)-2-thiophen-carboxamider og anvendelsen heraf på området for koagulering

Country Status (42)

Country Link
US (2) US8383822B2 (da)
EP (1) EP2170877B1 (da)
JP (1) JP5537421B2 (da)
KR (1) KR101535312B1 (da)
CN (1) CN101821259B (da)
AR (2) AR066981A1 (da)
AU (1) AU2008266525B8 (da)
BR (1) BRPI0813736A2 (da)
CA (1) CA2692166C (da)
CL (1) CL2008001691A1 (da)
CO (1) CO6251281A2 (da)
CR (1) CR11168A (da)
CU (1) CU23820A3 (da)
CY (1) CY1113580T1 (da)
DE (1) DE102007028319A1 (da)
DK (1) DK2170877T5 (da)
DO (1) DOP2009000285A (da)
EC (1) ECSP099807A (da)
ES (1) ES2397799T3 (da)
GT (1) GT200900319A (da)
HN (1) HN2009003424A (da)
HR (1) HRP20130072T1 (da)
IL (1) IL202351A (da)
JO (1) JO2798B1 (da)
MA (1) MA31535B1 (da)
MX (1) MX2009013711A (da)
MY (1) MY150931A (da)
NZ (1) NZ581540A (da)
PA (1) PA8784301A1 (da)
PE (1) PE20090332A1 (da)
PL (1) PL2170877T3 (da)
PT (1) PT2170877E (da)
RS (1) RS52639B (da)
RU (1) RU2481345C2 (da)
SG (1) SG182220A1 (da)
SI (1) SI2170877T1 (da)
SV (1) SV2009003435A (da)
TN (1) TN2009000503A1 (da)
TW (1) TWI413642B (da)
UA (1) UA98793C2 (da)
UY (1) UY31133A1 (da)
WO (1) WO2008155032A1 (da)

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CA2824885A1 (en) 2011-01-19 2012-07-26 Bayer Intellectual Property Gmbh Binding proteins to inhibitors of coagulation factors
CN103626749A (zh) * 2012-08-21 2014-03-12 苏州泽璟生物制药有限公司 取代的噁唑烷酮化合物和包含该化合物的药物组合物及其用途
CN103232446B (zh) * 2013-05-17 2015-09-23 天津药物研究院 一种噁唑烷酮衍生物晶型ⅱ及其制备方法和用途
WO2014183667A1 (zh) * 2013-05-17 2014-11-20 天津药物研究院 一种噁唑烷酮衍生物的乙酸溶剂化物及其制备方法和用途
CN103242307B (zh) * 2013-05-17 2015-08-12 天津药物研究院有限公司 一种噁唑烷酮类衍生物晶型ⅰ及其制备方法和用途

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Also Published As

Publication number Publication date
DK2170877T3 (da) 2013-02-11
HK1147991A1 (en) 2011-08-26
US8383822B2 (en) 2013-02-26
UA98793C2 (ru) 2012-06-25
HN2009003424A (es) 2012-01-05
DE102007028319A1 (de) 2008-12-24
IL202351A0 (en) 2010-06-30
ECSP099807A (es) 2010-01-29
MX2009013711A (es) 2010-02-01
AU2008266525B2 (en) 2013-09-05
JO2798B1 (en) 2014-03-15
ES2397799T3 (es) 2013-03-11
RS52639B (sr) 2013-06-28
CO6251281A2 (es) 2011-02-21
PA8784301A1 (es) 2009-02-09
TN2009000503A1 (en) 2011-03-31
US20140057951A1 (en) 2014-02-27
IL202351A (en) 2015-10-29
UY31133A1 (es) 2009-01-30
AR066981A1 (es) 2009-09-23
EP2170877B1 (de) 2012-11-21
RU2481345C2 (ru) 2013-05-10
WO2008155032A1 (de) 2008-12-24
KR20100021615A (ko) 2010-02-25
SV2009003435A (es) 2010-08-23
TW200911797A (en) 2009-03-16
DOP2009000285A (es) 2010-01-31
BRPI0813736A2 (pt) 2014-12-30
PE20090332A1 (es) 2009-04-09
CU23820A3 (es) 2012-06-21
CA2692166C (en) 2015-01-27
CA2692166A1 (en) 2008-12-24
KR101535312B1 (ko) 2015-07-09
GT200900319A (es) 2011-11-09
RU2010101307A (ru) 2011-07-27
CN101821259B (zh) 2013-10-30
CN101821259A (zh) 2010-09-01
CU20090216A7 (es) 2011-10-14
CR11168A (es) 2010-06-28
CY1113580T1 (el) 2016-06-22
AU2008266525B8 (en) 2013-09-19
JP2010530383A (ja) 2010-09-09
NZ581540A (en) 2012-01-12
SI2170877T1 (sl) 2013-03-29
US20100184740A1 (en) 2010-07-22
JP5537421B2 (ja) 2014-07-02
SG182220A1 (en) 2012-07-30
AU2008266525A1 (en) 2008-12-24
EP2170877A1 (de) 2010-04-07
AR067057A1 (es) 2009-09-30
TWI413642B (zh) 2013-11-01
MA31535B1 (fr) 2010-07-01
PL2170877T3 (pl) 2013-03-29
MY150931A (en) 2014-03-14
HRP20130072T1 (hr) 2013-02-28
US8846934B2 (en) 2014-09-30
CL2008001691A1 (es) 2008-12-26
PT2170877E (pt) 2013-01-28

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