MA31535B1 - (oxazolidinon-5-yl-méthyl)-2-thiophène-carboxamides substitués et leur utilisation dans le domaine de la coagulation sanguine - Google Patents

(oxazolidinon-5-yl-méthyl)-2-thiophène-carboxamides substitués et leur utilisation dans le domaine de la coagulation sanguine

Info

Publication number
MA31535B1
MA31535B1 MA32539A MA32539A MA31535B1 MA 31535 B1 MA31535 B1 MA 31535B1 MA 32539 A MA32539 A MA 32539A MA 32539 A MA32539 A MA 32539A MA 31535 B1 MA31535 B1 MA 31535B1
Authority
MA
Morocco
Prior art keywords
thiophener
oxazolidinon
carboxamides
substituted
methyl
Prior art date
Application number
MA32539A
Other languages
English (en)
Inventor
Swen Allerheiligen
Marcus Bauser
Dirk Heimbach
Stefan Heitmeier
Mark Jean Gnoth
Christoph Gerdes
Degenfeld Georges Von
Susanne Roehrig
Ulrich Rester
Elke Dittrich-Wengenroth
Uwe Saatmann
Adrian Tersteegen
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39731148&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA31535(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of MA31535B1 publication Critical patent/MA31535B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

L'INVENTION CONCERNE DE NOUVELLES OXAZOLIDINONES SUBSTITUÉES, DES PROCÉDÉS POUR LEUR PRODUCTION, LEUR UTILISATION POUR LE TRAITEMENT ET/OU LA PROPHYLAXIE DE MALADIES, AINSI QUE LEUR UTILISATION POUR PRODUIRE DES MÉDICAMENTS SERVANT AU TRAITEMENT ET/OU À LA PROPHYLAXIE DE MALADIES, NOTAMMENT DE MALADIES THROMBOEMBOLIQUES.
MA32539A 2007-06-20 2010-01-19 (oxazolidinon-5-yl-méthyl)-2-thiophène-carboxamides substitués et leur utilisation dans le domaine de la coagulation sanguine MA31535B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102007028319A DE102007028319A1 (de) 2007-06-20 2007-06-20 Substituierte Oxazolidinone und ihre Verwendung

Publications (1)

Publication Number Publication Date
MA31535B1 true MA31535B1 (fr) 2010-07-01

Family

ID=39731148

Family Applications (1)

Application Number Title Priority Date Filing Date
MA32539A MA31535B1 (fr) 2007-06-20 2010-01-19 (oxazolidinon-5-yl-méthyl)-2-thiophène-carboxamides substitués et leur utilisation dans le domaine de la coagulation sanguine

Country Status (42)

Country Link
US (2) US8383822B2 (fr)
EP (1) EP2170877B1 (fr)
JP (1) JP5537421B2 (fr)
KR (1) KR101535312B1 (fr)
CN (1) CN101821259B (fr)
AR (2) AR066981A1 (fr)
AU (1) AU2008266525B8 (fr)
BR (1) BRPI0813736A2 (fr)
CA (1) CA2692166C (fr)
CL (1) CL2008001691A1 (fr)
CO (1) CO6251281A2 (fr)
CR (1) CR11168A (fr)
CU (1) CU23820A3 (fr)
CY (1) CY1113580T1 (fr)
DE (1) DE102007028319A1 (fr)
DK (1) DK2170877T5 (fr)
DO (1) DOP2009000285A (fr)
EC (1) ECSP099807A (fr)
ES (1) ES2397799T3 (fr)
GT (1) GT200900319A (fr)
HN (1) HN2009003424A (fr)
HR (1) HRP20130072T1 (fr)
IL (1) IL202351A (fr)
JO (1) JO2798B1 (fr)
MA (1) MA31535B1 (fr)
MX (1) MX2009013711A (fr)
MY (1) MY150931A (fr)
NZ (1) NZ581540A (fr)
PA (1) PA8784301A1 (fr)
PE (1) PE20090332A1 (fr)
PL (1) PL2170877T3 (fr)
PT (1) PT2170877E (fr)
RS (1) RS52639B (fr)
RU (1) RU2481345C2 (fr)
SG (1) SG182220A1 (fr)
SI (1) SI2170877T1 (fr)
SV (1) SV2009003435A (fr)
TN (1) TN2009000503A1 (fr)
TW (1) TWI413642B (fr)
UA (1) UA98793C2 (fr)
UY (1) UY31133A1 (fr)
WO (1) WO2008155032A1 (fr)

Families Citing this family (10)

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DE102006039589A1 (de) * 2006-08-24 2008-03-06 Bayer Healthcare Ag Aminoacyl-Prodrugs II
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DE102010028362A1 (de) 2010-04-29 2011-11-03 Bayer Schering Pharma Aktiengesellschaft Herstellverfahren
CN102464658B (zh) * 2010-11-03 2014-04-16 天津药物研究院 噁唑烷酮衍生物及其制备方法和用途
CN103619883A (zh) 2011-01-19 2014-03-05 拜耳知识产权有限责任公司 凝血因子抑制剂的结合蛋白
CN103626749A (zh) * 2012-08-21 2014-03-12 苏州泽璟生物制药有限公司 取代的噁唑烷酮化合物和包含该化合物的药物组合物及其用途
CN103242307B (zh) * 2013-05-17 2015-08-12 天津药物研究院有限公司 一种噁唑烷酮类衍生物晶型ⅰ及其制备方法和用途
CN103232446B (zh) * 2013-05-17 2015-09-23 天津药物研究院 一种噁唑烷酮衍生物晶型ⅱ及其制备方法和用途
CN104163819A (zh) * 2013-05-17 2014-11-26 天津药物研究院 一种噁唑烷酮衍生物的乙酸溶剂化物及其制备方法和用途

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Also Published As

Publication number Publication date
CN101821259B (zh) 2013-10-30
AR067057A1 (es) 2009-09-30
AU2008266525B2 (en) 2013-09-05
US20100184740A1 (en) 2010-07-22
KR20100021615A (ko) 2010-02-25
DOP2009000285A (es) 2010-01-31
MX2009013711A (es) 2010-02-01
US20140057951A1 (en) 2014-02-27
AR066981A1 (es) 2009-09-23
RU2010101307A (ru) 2011-07-27
SG182220A1 (en) 2012-07-30
TWI413642B (zh) 2013-11-01
CU23820A3 (es) 2012-06-21
JP5537421B2 (ja) 2014-07-02
JO2798B1 (en) 2014-03-15
TW200911797A (en) 2009-03-16
ES2397799T3 (es) 2013-03-11
DK2170877T5 (da) 2013-03-04
UY31133A1 (es) 2009-01-30
PL2170877T3 (pl) 2013-03-29
BRPI0813736A2 (pt) 2014-12-30
CL2008001691A1 (es) 2008-12-26
RS52639B (sr) 2013-06-28
SV2009003435A (es) 2010-08-23
US8846934B2 (en) 2014-09-30
CN101821259A (zh) 2010-09-01
CO6251281A2 (es) 2011-02-21
HK1147991A1 (en) 2011-08-26
AU2008266525B8 (en) 2013-09-19
DK2170877T3 (da) 2013-02-11
CA2692166C (fr) 2015-01-27
US8383822B2 (en) 2013-02-26
HN2009003424A (es) 2012-01-05
JP2010530383A (ja) 2010-09-09
DE102007028319A1 (de) 2008-12-24
ECSP099807A (es) 2010-01-29
NZ581540A (en) 2012-01-12
AU2008266525A1 (en) 2008-12-24
IL202351A0 (en) 2010-06-30
SI2170877T1 (sl) 2013-03-29
HRP20130072T1 (hr) 2013-02-28
CR11168A (es) 2010-06-28
PE20090332A1 (es) 2009-04-09
PT2170877E (pt) 2013-01-28
WO2008155032A1 (fr) 2008-12-24
RU2481345C2 (ru) 2013-05-10
CU20090216A7 (es) 2011-10-14
PA8784301A1 (es) 2009-02-09
GT200900319A (es) 2011-11-09
UA98793C2 (ru) 2012-06-25
TN2009000503A1 (en) 2011-03-31
MY150931A (en) 2014-03-14
KR101535312B1 (ko) 2015-07-09
CA2692166A1 (fr) 2008-12-24
CY1113580T1 (el) 2016-06-22
EP2170877A1 (fr) 2010-04-07
IL202351A (en) 2015-10-29
EP2170877B1 (fr) 2012-11-21

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