DK2190987T3 - Fremgangsmåder til dannelse af disulfidbindinger - Google Patents

Fremgangsmåder til dannelse af disulfidbindinger

Info

Publication number
DK2190987T3
DK2190987T3 DK08787375.8T DK08787375T DK2190987T3 DK 2190987 T3 DK2190987 T3 DK 2190987T3 DK 08787375 T DK08787375 T DK 08787375T DK 2190987 T3 DK2190987 T3 DK 2190987T3
Authority
DK
Denmark
Prior art keywords
methods
disulfide bonds
forming disulfide
forming
bonds
Prior art date
Application number
DK08787375.8T
Other languages
English (en)
Inventor
Josef Prassler
Yvonne Stark
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Application granted granted Critical
Publication of DK2190987T3 publication Critical patent/DK2190987T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK08787375.8T 2007-08-21 2008-08-21 Fremgangsmåder til dannelse af disulfidbindinger DK2190987T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95702707P 2007-08-21 2007-08-21
US98903507P 2007-11-19 2007-11-19
PCT/EP2008/060931 WO2009024593A1 (en) 2007-08-21 2008-08-21 Improved methods for the formation of disulphide bonds

Publications (1)

Publication Number Publication Date
DK2190987T3 true DK2190987T3 (da) 2013-02-18

Family

ID=39929757

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08787375.8T DK2190987T3 (da) 2007-08-21 2008-08-21 Fremgangsmåder til dannelse af disulfidbindinger

Country Status (14)

Country Link
US (1) US9062097B2 (da)
EP (1) EP2190987B1 (da)
JP (2) JP2011504722A (da)
KR (1) KR20100089816A (da)
CN (1) CN101772574B (da)
AU (1) AU2008290539B2 (da)
CA (1) CA2694364C (da)
DK (1) DK2190987T3 (da)
ES (1) ES2403904T3 (da)
IL (1) IL203093A0 (da)
MX (1) MX2010000232A (da)
RU (1) RU2010102859A (da)
WO (1) WO2009024593A1 (da)
ZA (1) ZA201000975B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9062097B2 (en) 2007-08-21 2015-06-23 Morpho Sys AG Methods for the formation of disulphide bonds
CA2758356C (en) 2009-05-29 2016-07-26 Morphosys Ag A collection of vh and vl pairs having favourable biophysical properties and methods for its use
US8367586B2 (en) 2010-11-19 2013-02-05 Morphosys Ag Collection and methods for its use
JP6093715B2 (ja) * 2011-01-28 2017-03-08 ナショナル リサーチ カウンシル オブ カナダ 免疫グロブリンドメインの工学的作製
EP3774926A1 (en) 2018-04-05 2021-02-17 Bio-Rad ABD Serotec GmbH Display systems for proteins of interest
WO2025111511A2 (en) * 2023-11-21 2025-05-30 Calico Life Sciences Llc Reversibly reactive affinity selection mass spectrometry and uses thereof

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US5945311A (en) * 1994-06-03 1999-08-31 GSF--Forschungszentrumfur Umweltund Gesundheit Method for producing heterologous bi-specific antibodies
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US6046166A (en) * 1997-09-29 2000-04-04 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
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PT1652920E (pt) * 2001-10-01 2010-11-08 Deutsches Krebsforsch Processo para a produção de bibliotecas de proteínas e para a selecção de proteínas a partir da mesma
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Also Published As

Publication number Publication date
WO2009024593A1 (en) 2009-02-26
JP2015037419A (ja) 2015-02-26
EP2190987A1 (en) 2010-06-02
CA2694364A1 (en) 2009-02-26
CA2694364C (en) 2016-11-22
CN101772574A (zh) 2010-07-07
ES2403904T3 (es) 2013-05-22
IL203093A0 (en) 2011-08-01
AU2008290539A1 (en) 2009-02-26
ZA201000975B (en) 2010-11-24
JP2011504722A (ja) 2011-02-17
RU2010102859A (ru) 2011-09-27
CN101772574B (zh) 2016-01-06
AU2008290539B2 (en) 2013-07-25
JP6181626B2 (ja) 2017-08-16
MX2010000232A (es) 2010-06-02
EP2190987B1 (en) 2012-11-14
US20100190234A1 (en) 2010-07-29
US9062097B2 (en) 2015-06-23
KR20100089816A (ko) 2010-08-12

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