|
US6696251B1
(en)
|
1996-05-31 |
2004-02-24 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
|
US6759243B2
(en)
|
1998-01-20 |
2004-07-06 |
Board Of Trustees Of The University Of Illinois |
High affinity TCR proteins and methods
|
|
US8288322B2
(en)
|
2000-04-17 |
2012-10-16 |
Dyax Corp. |
Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
|
|
CA2429544C
(en)
*
|
2000-11-17 |
2010-10-19 |
University Of Rochester |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
|
US20050196755A1
(en)
*
|
2000-11-17 |
2005-09-08 |
Maurice Zauderer |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
|
ES2390425T3
(es)
|
2000-12-22 |
2012-11-12 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Uso de moléculas de orientación repulsivas (RGM) y sus moduladores
|
|
US20090137416A1
(en)
|
2001-01-16 |
2009-05-28 |
Regeneron Pharmaceuticals, Inc. |
Isolating Cells Expressing Secreted Proteins
|
|
US20030104402A1
(en)
*
|
2001-01-23 |
2003-06-05 |
University Of Rochester |
Methods of producing or identifying intrabodies in eukaryotic cells
|
|
WO2003029456A1
(en)
*
|
2001-10-01 |
2003-04-10 |
Dyax Corp. |
Multi-chain eukaryotic display vectors and uses thereof
|
|
US20040067532A1
(en)
|
2002-08-12 |
2004-04-08 |
Genetastix Corporation |
High throughput generation and affinity maturation of humanized antibody
|
|
JP2007524348A
(ja)
|
2003-01-07 |
2007-08-30 |
ダイアックス、コープ |
クニッツドメインライブラリー
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
ES2393555T3
(es)
|
2003-10-22 |
2012-12-26 |
Keck Graduate Institute |
Métodos para la síntesis de polipéptidos hetero-multiméricos en levaduras usando una estrategia de apareamiento haploide.
|
|
US20050100965A1
(en)
|
2003-11-12 |
2005-05-12 |
Tariq Ghayur |
IL-18 binding proteins
|
|
CA2550933A1
(en)
|
2003-12-22 |
2005-07-14 |
Amgen Inc. |
Methods for identifying functional antibodies
|
|
US20090298195A1
(en)
|
2005-01-05 |
2009-12-03 |
F-Star Biotechnologische Forschungs-Und Entwicklun Gseges M.B.H. |
Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
|
|
CN103146708A
(zh)
*
|
2005-06-30 |
2013-06-12 |
Abbvie公司 |
Il-12/p40结合蛋白
|
|
US7612181B2
(en)
*
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
JP5364870B2
(ja)
|
2005-08-19 |
2013-12-11 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリン及びその使用
|
|
EP2500353A3
(en)
|
2005-08-19 |
2012-10-10 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
US20090215992A1
(en)
*
|
2005-08-19 |
2009-08-27 |
Chengbin Wu |
Dual variable domain immunoglobulin and uses thereof
|
|
CN101277974A
(zh)
|
2005-09-30 |
2008-10-01 |
阿伯特有限及两合公司 |
排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
|
|
EP1943332A4
(en)
*
|
2005-10-14 |
2011-04-13 |
Medimmune Inc |
CELLULAR DISPLAY OF ANTIBODY LIBRARIES
|
|
PT1976877E
(pt)
|
2005-11-30 |
2014-04-29 |
Abbvie Inc |
Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações
|
|
BRPI0619249A2
(pt)
|
2005-11-30 |
2011-09-20 |
Abbott Lab |
anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos
|
|
US7845537B2
(en)
|
2006-01-31 |
2010-12-07 |
Ethicon Endo-Surgery, Inc. |
Surgical instrument having recording capabilities
|
|
US8992422B2
(en)
|
2006-03-23 |
2015-03-31 |
Ethicon Endo-Surgery, Inc. |
Robotically-controlled endoscopic accessory channel
|
|
JP2009535063A
(ja)
*
|
2006-05-04 |
2009-10-01 |
アブマクシス・インコーポレイテツド |
異種間及び複数種提示系
|
|
NZ596269A
(en)
|
2006-07-05 |
2012-12-21 |
Catalyst Biosciences Inc |
Protease screening methods and proteases identified thereby
|
|
AT503889B1
(de)
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
|
PL3339445T3
(pl)
*
|
2006-09-08 |
2020-12-14 |
Abbvie Bahamas Ltd. |
Białka wiążące interleukinę 13
|
|
US7732195B2
(en)
|
2006-11-01 |
2010-06-08 |
Facet Biotech Corporation |
Tethered vectors for cell surface immunoglobulin display
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
US20110076752A1
(en)
*
|
2007-02-09 |
2011-03-31 |
Medimmune, Llc |
Antibody library display by yeast cell plasma membrane
|
|
EP2124952A2
(en)
|
2007-02-27 |
2009-12-02 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
US8709980B2
(en)
|
2007-03-26 |
2014-04-29 |
Celexion, Llc |
Cell surface display, screening and production of proteins of interest
|
|
EP2134853B1
(en)
|
2007-04-03 |
2018-07-18 |
Oxyrane UK Limited |
Glycosylation of molecules
|
|
US20090232801A1
(en)
*
|
2007-05-30 |
2009-09-17 |
Abbot Laboratories |
Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof
|
|
PE20090329A1
(es)
*
|
2007-05-30 |
2009-03-27 |
Abbott Lab |
Anticuerpos humanizados contra el globulomero ab(20-42) y sus usos
|
|
PL3241842T3
(pl)
|
2007-06-26 |
2024-06-10 |
F-Star Therapeutics Limited |
Prezentacja środków wiążących
|
|
KR20100089816A
(ko)
|
2007-08-21 |
2010-08-12 |
모르포시스 아게 |
이황화 결합을 형성하기 위한 개선된 방법
|
|
US8877688B2
(en)
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
EP3124497B1
(en)
|
2007-09-14 |
2020-04-15 |
Adimab, LLC |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
US12529164B2
(en)
|
2007-09-14 |
2026-01-20 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
WO2009059235A2
(en)
*
|
2007-11-01 |
2009-05-07 |
Facet Biotech Corporation |
Immunoglobulin display vectors
|
|
US8637435B2
(en)
*
|
2007-11-16 |
2014-01-28 |
Merck Sharp & Dohme Corp. |
Eukaryotic cell display systems
|
|
EP2229473A4
(en)
|
2007-12-07 |
2011-02-02 |
Steven A Goldstein |
IDENTIFICATION OF TOXIN LIGANDS
|
|
US20100317546A1
(en)
*
|
2008-01-11 |
2010-12-16 |
Morphosys Ag |
Display Vectors and Methods and Uses Thereof
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
EP2263089B1
(en)
*
|
2008-03-03 |
2015-01-28 |
GlycoFi, Inc. |
Surface display of recombinant proteins in lower eukaryotes
|
|
EP2098536A1
(en)
|
2008-03-05 |
2009-09-09 |
4-Antibody AG |
Isolation and identification of antigen- or ligand-specific binding proteins
|
|
WO2009114815A1
(en)
|
2008-03-13 |
2009-09-17 |
Dyax Corp |
Libraries of genetic packages comprising novel hc cdr3 designs
|
|
WO2009132287A2
(en)
|
2008-04-24 |
2009-10-29 |
Dyax Corp. |
Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
|
|
TWI593423B
(zh)
|
2008-04-25 |
2017-08-01 |
戴埃克斯有限公司 |
Fc受體結合蛋白
|
|
JP5646457B2
(ja)
|
2008-04-29 |
2014-12-24 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリン及びその使用
|
|
EP2113255A1
(en)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Cytotoxic immunoglobulin
|
|
RU2518351C2
(ru)
|
2008-05-09 |
2014-06-10 |
Эббви Дойчланд Гмбх Унд Ко.Кг, |
Антитела к рецептору конечных продуктов глубокого гликирования (rage) и их применения
|
|
PE20100054A1
(es)
|
2008-06-03 |
2010-03-03 |
Abbott Lab |
Inmunoglobulina con dominio variable dual
|
|
EP3002299A1
(en)
|
2008-06-03 |
2016-04-06 |
AbbVie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
MX2010014574A
(es)
|
2008-07-08 |
2011-04-27 |
Abbott Lab |
Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas.
|
|
RU2559525C2
(ru)
|
2008-07-08 |
2015-08-10 |
Эббви Инк |
Белки, связывающие простагландин е2, и их применение
|
|
US8067339B2
(en)
*
|
2008-07-09 |
2011-11-29 |
Merck Sharp & Dohme Corp. |
Surface display of whole antibodies in eukaryotes
|
|
JP2012504424A
(ja)
|
2008-10-03 |
2012-02-23 |
ゾーマ テクノロジー リミテッド |
トリプルタグ配列およびその使用方法
|
|
WO2010045315A1
(en)
|
2008-10-14 |
2010-04-22 |
Dyax Corp. |
Use of igf-ii/igf-iie binding for the treatment and prevention of systemic sclerosis associated pulmonary fibrosis
|
|
US20100233079A1
(en)
*
|
2008-12-04 |
2010-09-16 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
|
CN102245771B
(zh)
*
|
2008-12-16 |
2013-04-10 |
诺瓦提斯公司 |
酵母展示系统
|
|
WO2010079189A1
(en)
*
|
2009-01-09 |
2010-07-15 |
Morphosys Ag |
Display vectors and methods and uses thereof
|
|
US20110165063A1
(en)
*
|
2009-01-29 |
2011-07-07 |
Abbott Laboratories |
Il-1 binding proteins
|
|
CN102369217A
(zh)
*
|
2009-01-29 |
2012-03-07 |
雅培制药有限公司 |
Il-1结合蛋白
|
|
US8030026B2
(en)
|
2009-02-24 |
2011-10-04 |
Abbott Laboratories |
Antibodies to troponin I and methods of use thereof
|
|
TW201613969A
(en)
*
|
2009-03-05 |
2016-04-16 |
Abbvie Inc |
IL-17 binding proteins
|
|
WO2010136598A1
(en)
|
2009-05-29 |
2010-12-02 |
Morphosys Ag |
A collection and methods for its use
|
|
US8623358B2
(en)
|
2009-08-29 |
2014-01-07 |
Abbvie Inc. |
Therapeutic DLL4 binding proteins
|
|
AR078254A1
(es)
|
2009-09-01 |
2011-10-26 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
JP2013504602A
(ja)
|
2009-09-14 |
2013-02-07 |
ダイアックス コーポレーション |
新しく設計したhccdr3を含む遺伝子パッケージライブラリー
|
|
US20110189183A1
(en)
|
2009-09-18 |
2011-08-04 |
Robert Anthony Williamson |
Antibodies against candida, collections thereof and methods of use
|
|
US9598682B2
(en)
|
2009-09-29 |
2017-03-21 |
Vib Vzw |
Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose
|
|
MX2012004415A
(es)
|
2009-10-15 |
2012-05-08 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
WO2011053707A1
(en)
*
|
2009-10-31 |
2011-05-05 |
Abbott Laboratories |
Antibodies to receptor for advanced glycation end products (rage) and uses thereof
|
|
US9244063B2
(en)
|
2009-11-11 |
2016-01-26 |
Gentian As |
Immunoassay for assessing related analytes of different origin
|
|
JP2013511272A
(ja)
|
2009-11-19 |
2013-04-04 |
オキシレイン ユーケー リミテッド |
哺乳類様複合n−グリカンを生成する酵母株
|
|
KR20120118002A
(ko)
|
2009-12-08 |
2012-10-25 |
애보트 게엠베하 운트 콤파니 카게 |
망막 신경 섬유 층 변성의 치료에 사용하기 위한 rgm a 단백질에 대한 모노클로날 항체
|
|
ES2688093T3
(es)
|
2010-01-06 |
2018-10-30 |
Dyax Corp. |
Proteínas de unión a calicreína plasmática
|
|
CN102803491A
(zh)
*
|
2010-01-21 |
2012-11-28 |
奥克西雷恩英国有限公司 |
用于在酵母细胞表面上展示多肽的方法和组合物
|
|
WO2011092233A1
(en)
|
2010-01-29 |
2011-08-04 |
Novartis Ag |
Yeast mating to produce high-affinity combinations of fibronectin-based binders
|
|
EP2542582A4
(en)
|
2010-03-02 |
2013-12-04 |
Abbvie Inc |
THERAPEUTIC PROTEINS LINKING TO DLL4
|
|
EP2558494B1
(en)
|
2010-04-15 |
2018-05-23 |
AbbVie Inc. |
Amyloid-beta binding proteins
|
|
AU2011252883B2
(en)
|
2010-05-14 |
2015-09-10 |
Abbvie Inc. |
IL-1 binding proteins
|
|
WO2012006500A2
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
KR102024922B1
(ko)
|
2010-07-16 |
2019-09-25 |
아디맵 엘엘씨 |
항체 라이브러리
|
|
US8735546B2
(en)
|
2010-08-03 |
2014-05-27 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
CN105348387B
(zh)
|
2010-08-14 |
2020-08-25 |
Abbvie 公司 |
β淀粉样蛋白结合蛋白
|
|
WO2012024650A2
(en)
|
2010-08-19 |
2012-02-23 |
Abbott Laboratories |
Anti-ngf antibodies and their use
|
|
PH12013500337A1
(en)
|
2010-08-26 |
2017-08-23 |
Abbvie Inc |
Dual variable domain immunoglobulins and uses thereof
|
|
SG189110A1
(en)
|
2010-09-29 |
2013-05-31 |
Oxyrane Uk Ltd |
De-mannosylation of phosphorylated n-glycans
|
|
WO2012042386A2
(en)
|
2010-09-29 |
2012-04-05 |
Oxyrane Uk Limited |
Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated n-glycans and methods of facilitating mammalian cellular uptake of glycoproteins
|
|
WO2012052391A1
(en)
|
2010-10-19 |
2012-04-26 |
Glaxo Group Limited |
Polypeptide with jmjd3 catalytic activity
|
|
HRP20181811T1
(hr)
|
2010-11-19 |
2018-12-28 |
Morphosys Ag |
Zbirka sljedova protutijela i njezina upotreba
|
|
WO2012121775A2
(en)
|
2010-12-21 |
2012-09-13 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
|
TW201307388A
(zh)
|
2010-12-21 |
2013-02-16 |
Abbott Lab |
Il-1結合蛋白
|
|
PH12013502378A1
(en)
|
2011-06-02 |
2014-01-06 |
Dyax Corp |
Fc RECEPTOR BINDING PROTEINS
|
|
RU2640025C2
(ru)
|
2011-07-13 |
2017-12-25 |
Эббви Инк. |
Способы и композиции для лечения астмы с использованием антител против il-13
|
|
EP2771360A1
(en)
|
2011-10-24 |
2014-09-03 |
AbbVie Inc. |
Immunobinders directed against sclerostin
|
|
AR088512A1
(es)
|
2011-10-24 |
2014-06-18 |
Abbvie Inc |
Anticuerpos dirigidos contra el tnf
|
|
JP2015501639A
(ja)
|
2011-11-23 |
2015-01-19 |
アイジェニカ バイオセラピューティクス インコーポレイテッド |
抗cd98抗体およびその使用方法
|
|
CN104144947B
(zh)
|
2011-12-14 |
2017-10-27 |
艾伯维德国有限责任两合公司 |
用于诊断和治疗铁相关病症的组合物和方法
|
|
EP2791175A2
(en)
|
2011-12-14 |
2014-10-22 |
Abbvie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
|
US9120870B2
(en)
|
2011-12-30 |
2015-09-01 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-13 and IL-17
|
|
EP3369746A1
(en)
|
2012-01-27 |
2018-09-05 |
AbbVie Deutschland GmbH & Co KG |
Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
|
|
JP6194324B2
(ja)
|
2012-03-15 |
2017-09-06 |
オキシレイン ユーケー リミテッド |
ポンペ病の処置のための方法および材料
|
|
EP2644693A1
(en)
*
|
2012-03-29 |
2013-10-02 |
IP Bewertungs AG (IPB) |
Biologically active polypertide expressed on the surface of a cell
|
|
JP6629069B2
(ja)
|
2012-06-06 |
2020-01-15 |
ゾエティス・エルエルシー |
イヌ化抗ngf抗体およびその方法
|
|
TW201402608A
(zh)
|
2012-07-12 |
2014-01-16 |
Abbvie Inc |
Il-1結合蛋白質
|
|
JP2015533832A
(ja)
|
2012-10-09 |
2015-11-26 |
アイジェニカ バイオセラピューティクス インコーポレイテッド |
抗C16orf54抗体およびその使用方法
|
|
AU2013337775B2
(en)
|
2012-11-01 |
2017-03-30 |
Abbvie Inc. |
Anti-VEGF/DLL4 dual variable domain immunoglobulins and uses thereof
|
|
TW202423993A
(zh)
|
2012-11-14 |
2024-06-16 |
美商再生元醫藥公司 |
重組細胞表面捕捉蛋白質
|
|
WO2014100542A1
(en)
|
2012-12-21 |
2014-06-26 |
Abbvie, Inc. |
High-throughput antibody humanization
|
|
JP6505076B2
(ja)
|
2013-03-14 |
2019-04-24 |
アボット・ラボラトリーズAbbott Laboratories |
Hcv抗原−抗体組み合わせアッセイおよびこれに使用するための方法および組成物
|
|
EP2970947A4
(en)
|
2013-03-14 |
2016-10-12 |
Abbott Lab |
RECOMBINANT HCV NS3 ANTIGENS AND THEIR MUTANTS FOR ENHANCED ANTIBODY DETECTION
|
|
WO2014152013A1
(en)
|
2013-03-14 |
2014-09-25 |
The Trustees Of Columbia University In The City Of New York |
4-phenylpiperidines, their preparation and use
|
|
CN105378099B
(zh)
|
2013-03-14 |
2021-05-11 |
雅培制药有限公司 |
Hcv核心脂质结合结构域单克隆抗体
|
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
|
EP2970459A2
(en)
|
2013-03-15 |
2016-01-20 |
AbbVie Inc. |
Dual specific binding proteins directed against il-1beta and il-17
|
|
WO2014197885A2
(en)
|
2013-06-07 |
2014-12-11 |
Duke University |
Inhibitors of complement factor h
|
|
CA2931684C
(en)
|
2013-12-19 |
2024-02-20 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
|
PL3097122T3
(pl)
|
2014-01-24 |
2020-10-19 |
Ngm Biopharmaceuticals, Inc. |
Przeciwciała wiążące domenę 2 beta klotho oraz sposoby ich stosowania
|
|
EP3102245B1
(en)
|
2014-02-05 |
2021-09-08 |
Molecular Templates, Inc. |
Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicity
|
|
US10816554B2
(en)
|
2014-04-04 |
2020-10-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Ligand discovery for T cell receptors
|
|
US9777061B2
(en)
|
2014-07-21 |
2017-10-03 |
Novartis Ag |
Treatment of cancer using a CD33 chimeric antigen receptor
|
|
WO2016025880A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using gfr alpha-4 chimeric antigen receptor
|
|
SG11201700770PA
(en)
|
2014-08-19 |
2017-03-30 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
|
RU2715597C2
(ru)
|
2015-05-29 |
2020-03-02 |
Эббви Инк. |
Антитела к cd40 и способы их применения
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
|
EP3355920A4
(en)
|
2015-09-29 |
2019-05-15 |
Celgene Corporation |
PD-1 BINDING PROTEINS AND METHOD OF USE THEREOF
|
|
US11384354B2
(en)
*
|
2015-12-21 |
2022-07-12 |
Zumutor Biologics Inc. |
Method of generating an antibody naïve library, said library and application(s) thereof
|
|
RU2683549C1
(ru)
*
|
2015-12-29 |
2019-03-28 |
Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) |
СИСТЕМА ДЛЯ ЭКСПРЕССИИ FAB-ФРАГМЕНТОВ АНТИТЕЛ В МЕТИЛОТРОФНЫХ ДРОЖЖАХ PICHIAPASTORIS, НА ОСНОВЕ РЕКОМБИНАНТНЫХ ПЛАЗМИДНЫХ ДНК Ab-HCh-HIS/pPICZ_α_A И Ab-LCh-LAMBDA/pPICZα_A, ПРЕДНАЗНАЧЕННЫХ ДЛЯ КЛОНИРОВАНИЯ ВАРИАБЕЛЬНЫХ ДОМЕНОВ ТЯЖЕЛОЙ И ЛЕГКОЙ ЦЕПЕЙ АНТИТЕЛ, СООТВЕТСТВЕННО
|
|
US20170205421A1
(en)
*
|
2016-01-15 |
2017-07-20 |
University Of Washington |
Synthetic yeast agglutination
|
|
US10988759B2
(en)
|
2016-01-15 |
2021-04-27 |
University Of Washington |
High throughput protein-protein interaction screening in yeast liquid culture
|
|
SG11201900344YA
(en)
|
2016-07-15 |
2019-02-27 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
EP3515943A4
(en)
|
2016-09-19 |
2020-05-06 |
Celgene Corporation |
METHODS OF TREATING VITILIGO WITH PD-1 BINDING PROTEINS
|
|
WO2018053405A1
(en)
|
2016-09-19 |
2018-03-22 |
Celgene Corporation |
Methods of treating immune disorders using pd-1 binding proteins
|
|
EP4521116A3
(en)
|
2016-10-03 |
2025-05-28 |
Abbott Laboratories |
Improved methods of assessing uch-l1 status in patient samples
|
|
WO2018067992A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
US10815525B2
(en)
|
2016-12-22 |
2020-10-27 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10550429B2
(en)
|
2016-12-22 |
2020-02-04 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US11135164B2
(en)
|
2017-01-13 |
2021-10-05 |
Academia Sinica |
Reloadable hydrogel system comprising an anti-PEG antibody for treating myocardial infarction
|
|
WO2018130661A1
(en)
|
2017-01-13 |
2018-07-19 |
Academia Sinica |
Reloadable hydrogel system for treating brain conditions
|
|
CA3261113A1
(en)
|
2017-03-23 |
2025-10-27 |
Abbott Laboratories |
Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1
|
|
CN110546513A
(zh)
|
2017-04-15 |
2019-12-06 |
雅培实验室 |
使用早期生物标记物帮助超急性诊断和确定人类受试者中的创伤性脑损伤的方法
|
|
ES3053676T3
(en)
|
2017-04-28 |
2026-01-23 |
Abbott Lab |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
|
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
|
AU2018272054B2
(en)
|
2017-05-25 |
2024-10-31 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
|
JP7269182B2
(ja)
|
2017-05-30 |
2023-05-08 |
アボット・ラボラトリーズ |
心臓トロポニンi及び早期バイオマーカーを使用する、ヒト対象における軽度外傷性脳損傷を診断及び査定する一助となるための方法
|
|
CA3068041C
(en)
|
2017-07-03 |
2024-06-25 |
Abbott Laboratories |
Improved methods for measuring ubiquitin carboxy-terminal hydrolase l1 levels in blood
|
|
PT3428194T
(pt)
|
2017-07-14 |
2021-11-18 |
Immatics Biotechnologies Gmbh |
Molécula de polipéptido com especificidade dupla melhorada
|
|
EP3692370A2
(en)
|
2017-10-04 |
2020-08-12 |
OPKO Pharmaceuticals, LLC |
Articles and methods directed to personalized therapy of cancer
|
|
SG11202003652QA
(en)
|
2017-10-27 |
2020-05-28 |
Univ New York |
Anti-galectin-9 antibodies and uses thereof
|
|
US11022617B2
(en)
|
2017-12-09 |
2021-06-01 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (TBI), using glial fibrillary acidic protein (GFAP) and/or ubiquitin carboxy-terminal hydrolase L1 (UCH-L1)
|
|
EP3721234A1
(en)
|
2017-12-09 |
2020-10-14 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of gfap and uch-l1
|
|
SG11202007686VA
(en)
|
2018-02-12 |
2020-09-29 |
10X Genomics Inc |
Methods characterizing multiple analytes from individual cells or cell populations
|
|
MX2020009526A
(es)
|
2018-03-12 |
2020-10-28 |
Zoetis Services Llc |
Anticuerpos anti-ngf y metodos de estos.
|
|
WO2019217758A1
(en)
|
2018-05-10 |
2019-11-14 |
10X Genomics, Inc. |
Methods and systems for molecular library generation
|
|
EP3796977A4
(en)
*
|
2018-05-17 |
2022-03-02 |
The Board of Trustees of the Leland Stanford Junior University |
RECEPTOR INHIBITION BY PHOSPHATASE RECRUITMENT
|
|
MX2021003310A
(es)
|
2018-09-20 |
2021-07-15 |
Washington University St Louis |
Microorganismos genomodificados y métodos para producirlos y usarlos.
|
|
TW202028237A
(zh)
|
2018-09-27 |
2020-08-01 |
美商西建公司 |
SIRPα結合蛋白及其使用方法
|
|
EP3856773A1
(en)
|
2018-09-28 |
2021-08-04 |
Kyowa Kirin Co., Ltd. |
Il-36 antibodies and uses thereof
|
|
CN114144190B
(zh)
|
2019-01-23 |
2025-08-08 |
纽约大学 |
对T细胞受体的δ1链具有特异性的抗体
|
|
CN112567080A
(zh)
*
|
2019-04-22 |
2021-03-26 |
泷搌(上海)生物科技有限公司 |
制备噬菌体文库的方法
|
|
EP4100435A1
(en)
|
2020-02-05 |
2022-12-14 |
Larimar Therapeutics, Inc. |
Tat peptide binding proteins and uses thereof
|
|
US12449419B1
(en)
|
2020-02-12 |
2025-10-21 |
10X Genomics, Inc. |
Methods for detecting binding of peptide-MHC monomers to T cells
|
|
WO2021211331A1
(en)
|
2020-04-13 |
2021-10-21 |
Abbott Point Of Care Inc. |
METHODS, COMPLEXES AND KITS FOR DETECTING OR DETERMINING AN AMOUNT OF A ß-CORONAVIRUS ANTIBODY IN A SAMPLE
|
|
EP4150073A1
(en)
|
2020-05-11 |
2023-03-22 |
A-Alpha Bio, Inc. |
High-throughput screening methods to identify small molecule targets
|
|
KR20230012539A
(ko)
|
2020-05-13 |
2023-01-26 |
디스크 메디슨, 인크. |
골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
|
|
KR102563799B1
(ko)
|
2020-06-01 |
2023-08-03 |
에이-알파 바이오, 인크. |
단백질-단백질 상호작용 특징화 및 조작 방법
|
|
WO2022012680A1
(en)
|
2020-07-16 |
2022-01-20 |
Nanjing Legend Biotech Co., Ltd. |
Cd20 binding molecules and uses thereof
|
|
WO2022031576A1
(en)
|
2020-08-03 |
2022-02-10 |
Janssen Biotech, Inc. |
Materials and methods for multidirectional biotransportation in virotherapeutics
|
|
EP4193149A1
(en)
|
2020-08-04 |
2023-06-14 |
Abbott Laboratories |
Improved methods and kits for detecting sars-cov-2 protein in a sample
|
|
CN112646833A
(zh)
|
2020-11-05 |
2021-04-13 |
杭州阿诺生物医药科技有限公司 |
一种全人源抗体酵母展示技术的设计与构建
|
|
CA3198161A1
(en)
|
2020-12-01 |
2022-06-09 |
Beth MCQUISTON |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
EP4271998A1
(en)
|
2020-12-30 |
2023-11-08 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
|
JP2024502832A
(ja)
|
2020-12-31 |
2024-01-23 |
アラマー バイオサイエンシーズ, インコーポレイテッド |
高親和性及び/または特異性を有する結合剤分子ならびにその製造及び使用方法
|
|
BR112023022765A2
(pt)
|
2021-05-05 |
2024-01-02 |
Immatics Biotechnologies Gmbh |
Proteínas de ligação ao antígeno que ligam especificamente o prame
|
|
US20220381796A1
(en)
|
2021-05-18 |
2022-12-01 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
|
EP4356129A1
(en)
|
2021-06-14 |
2024-04-24 |
Abbott Laboratories |
Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
|
|
CN118715440A
(zh)
|
2021-08-31 |
2024-09-27 |
雅培实验室 |
诊断脑损伤的方法和系统
|
|
EP4396587A1
(en)
|
2021-08-31 |
2024-07-10 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
EP4144898A1
(de)
*
|
2021-09-07 |
2023-03-08 |
New/era/mabs GmbH |
Verfahren zur selektion oder screenen von antikörpern aus einer antikörperbibliothek
|
|
EP4409294A1
(en)
|
2021-09-30 |
2024-08-07 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
WO2023114978A1
(en)
|
2021-12-17 |
2023-06-22 |
Abbott Laboratories |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
|
UY40097A
(es)
|
2022-01-07 |
2023-07-14 |
Johnson & Johnson Entpr Innovation Inc |
Materiales y métodos de proteínas de unión a il-1b
|
|
EP4473311A1
(en)
|
2022-02-04 |
2024-12-11 |
Abbott Laboratories |
Lateral flow methods, assays, and devices for detecting the presence or measuring the amount of ubiquitin carboxy-terminal hydrolase l1 and/or glial fibrillary acidic protein in a sample
|
|
ES2955461B2
(es)
*
|
2022-05-24 |
2024-12-27 |
Univ Valencia Politecnica |
Levadura y plasmido para la exposicion de proteinas en superficie
|
|
CA3257731A1
(en)
|
2022-06-29 |
2024-01-04 |
Abbott Laboratories |
OUTSIDE THE LABORATORY, MAGNETIC SYSTEMS AND ANALYSES FOR DETERMINING GLIOFIBRILLARY ACID PROTEIN IN BIOLOGICAL SAMPLES
|
|
EP4554969A1
(en)
|
2022-07-15 |
2025-05-21 |
Janssen Biotech, Inc. |
Material and methods for improved bioengineered pairing of antigen-binding variable regions
|
|
JP2025532597A
(ja)
|
2022-09-15 |
2025-10-01 |
アボット・ラボラトリーズ |
軽度及び超軽度の外傷性脳損傷を区別するためのバイオマーカー及び方法
|
|
WO2024211475A1
(en)
|
2023-04-04 |
2024-10-10 |
Abbott Laboratories |
Use of biomarkers to determine whether a subject has sustained, may have sustained or is suspected of sustaining a subacute acquired brain injury (abi)
|
|
EP4713682A1
(en)
|
2023-04-28 |
2026-03-25 |
Abbott Point of Care Inc. |
Improved assays, cartridges, and kits for detection of biomarkers, including brain injury biomarkers
|