DK2379520T3 - Griseofulvin-analoger til behandling af cancer ved inhibering af centrosomal clusterdannelse - Google Patents
Griseofulvin-analoger til behandling af cancer ved inhibering af centrosomal clusterdannelseInfo
- Publication number
- DK2379520T3 DK2379520T3 DK09795784.9T DK09795784T DK2379520T3 DK 2379520 T3 DK2379520 T3 DK 2379520T3 DK 09795784 T DK09795784 T DK 09795784T DK 2379520 T3 DK2379520 T3 DK 2379520T3
- Authority
- DK
- Denmark
- Prior art keywords
- griseofulvine
- analogs
- inhibiting
- cancer treatment
- cluster formation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08172542A EP2204367A1 (en) | 2008-12-22 | 2008-12-22 | Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering |
| PCT/EP2009/067761 WO2010072770A2 (en) | 2008-12-22 | 2009-12-22 | Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2379520T3 true DK2379520T3 (da) | 2014-11-03 |
Family
ID=40668354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09795784.9T DK2379520T3 (da) | 2008-12-22 | 2009-12-22 | Griseofulvin-analoger til behandling af cancer ved inhibering af centrosomal clusterdannelse |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9108941B2 (da) |
| EP (2) | EP2204367A1 (da) |
| DK (1) | DK2379520T3 (da) |
| ES (1) | ES2522970T3 (da) |
| WO (1) | WO2010072770A2 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014020101A1 (fr) * | 2012-08-01 | 2014-02-06 | Pierre Fabre Medicament | Derives de griseofulvine |
| CN104860909B (zh) * | 2015-04-09 | 2017-03-08 | 西北农林科技大学 | 灰黄霉素衍生物、灰黄霉素及其衍生物的抗菌活性应用 |
| CA3018316C (en) | 2016-03-30 | 2021-02-16 | Daiichi Sankyo Company, Limited | Griseofulvin compound |
| TWI811243B (zh) | 2017-09-29 | 2023-08-11 | 日商第一三共股份有限公司 | 灰黃黴素化合物及醫藥用途 |
| CN108484552B (zh) * | 2018-06-15 | 2020-03-10 | 河南大学 | 一种多取代3-苯并呋喃酮螺环己烯衍生物及其制备方法 |
| CN108823110B (zh) * | 2018-07-26 | 2021-07-16 | 福州工微生物科技有限公司 | 一株产灰黄霉素的菌株及其应用 |
| CN112972478B (zh) * | 2021-02-07 | 2021-11-16 | 南通大学 | 灰黄霉素施密特重排衍生物在制备抗肿瘤药物中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3084102A (en) * | 1959-10-14 | 1963-04-02 | Ici Ltd | Fungicidal compositions |
| GB981521A (en) * | 1960-05-04 | 1965-01-27 | Glaxo Group Ltd | New analogues of griseofulvin and their preparation |
| JPH03255081A (ja) * | 1990-03-01 | 1991-11-13 | Mect Corp | dl―グリセオフルビン、dl―グリセオフルビン誘導体およびそれらの中間体の製造方法 |
| KR19990036137A (ko) | 1995-08-03 | 1999-05-25 | 데이비드 엠 모이어 | 암 성장을 억제하기 위한 그리세오풀빈의 용도 |
| US20050049207A1 (en) * | 2003-09-03 | 2005-03-03 | Kaufmann Doug A. | Method of treating and preventing cancer |
| EP2008652A1 (en) * | 2007-06-28 | 2008-12-31 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering |
-
2008
- 2008-12-22 EP EP08172542A patent/EP2204367A1/en not_active Withdrawn
-
2009
- 2009-12-22 EP EP09795784.9A patent/EP2379520B1/en not_active Not-in-force
- 2009-12-22 US US13/141,231 patent/US9108941B2/en not_active Expired - Fee Related
- 2009-12-22 WO PCT/EP2009/067761 patent/WO2010072770A2/en not_active Ceased
- 2009-12-22 ES ES09795784.9T patent/ES2522970T3/es active Active
- 2009-12-22 DK DK09795784.9T patent/DK2379520T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010072770A2 (en) | 2010-07-01 |
| EP2204367A1 (en) | 2010-07-07 |
| US9108941B2 (en) | 2015-08-18 |
| EP2379520B1 (en) | 2014-10-08 |
| ES2522970T3 (es) | 2014-11-19 |
| US20120035200A1 (en) | 2012-02-09 |
| EP2379520A2 (en) | 2011-10-26 |
| WO2010072770A3 (en) | 2010-12-23 |
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