DK2380896T3 - Fremgangsmåde til fremstilling af oligonukleotid - Google Patents

Fremgangsmåde til fremstilling af oligonukleotid

Info

Publication number
DK2380896T3
DK2380896T3 DK09817240.6T DK09817240T DK2380896T3 DK 2380896 T3 DK2380896 T3 DK 2380896T3 DK 09817240 T DK09817240 T DK 09817240T DK 2380896 T3 DK2380896 T3 DK 2380896T3
Authority
DK
Denmark
Prior art keywords
procedure
preparing oligonucleotide
oligonucleotide
preparing
Prior art date
Application number
DK09817240.6T
Other languages
English (en)
Inventor
Zhen Xi
Jinyu Huang
Junbin Zhang
Original Assignee
Suzhou Ribo Life Science Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Ribo Life Science Co Ltd filed Critical Suzhou Ribo Life Science Co Ltd
Application granted granted Critical
Publication of DK2380896T3 publication Critical patent/DK2380896T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
DK09817240.6T 2008-09-23 2009-09-22 Fremgangsmåde til fremstilling af oligonukleotid DK2380896T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200810149372A CN101684136A (zh) 2008-09-23 2008-09-23 一种寡核苷酸的制备方法
PCT/CN2009/074101 WO2010037326A1 (zh) 2008-09-23 2009-09-22 一种寡核苷酸的制备方法

Publications (1)

Publication Number Publication Date
DK2380896T3 true DK2380896T3 (da) 2013-05-13

Family

ID=42047540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09817240.6T DK2380896T3 (da) 2008-09-23 2009-09-22 Fremgangsmåde til fremstilling af oligonukleotid

Country Status (6)

Country Link
US (1) US8569476B2 (da)
EP (1) EP2380896B1 (da)
JP (1) JP5253578B2 (da)
CN (2) CN101684136A (da)
DK (1) DK2380896T3 (da)
WO (1) WO2010037326A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102344477B (zh) 2010-07-27 2015-04-08 苏州瑞博生物技术有限公司 一种核苷酸和/或寡核苷酸及其制备方法
WO2012157723A1 (ja) 2011-05-17 2012-11-22 味の素株式会社 オリゴヌクレオチドの製造方法
CN102827225B (zh) * 2011-06-14 2015-09-23 苏州瑞博生物技术有限公司 一种核苷酸和/或寡核苷酸及其制备方法
BR112022019752A2 (pt) * 2020-03-31 2022-11-16 Janssen Biopharma Inc Síntese de oligonucleotídeos e compostos relacionados

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE273064C (da)
DD273064A1 (de) * 1988-06-20 1989-11-01 Univ Dresden Tech Verfahren zur herstellung von oligonucleotiden
CN1093135C (zh) * 1998-08-21 2002-10-23 中国科学院上海生物化学研究所 固定化模板指导的寡核苷酸合成方法
GB9924285D0 (en) * 1999-10-14 1999-12-15 Avecia Ltd Process
UA96411C2 (en) * 2005-03-04 2011-11-10 Гириндус Аг Synthesis of oligonucleotides

Also Published As

Publication number Publication date
CN101868473A (zh) 2010-10-20
EP2380896B1 (en) 2013-02-13
CN101684136A (zh) 2010-03-31
JP2012502935A (ja) 2012-02-02
WO2010037326A1 (zh) 2010-04-08
US20110237786A1 (en) 2011-09-29
US8569476B2 (en) 2013-10-29
EP2380896A1 (en) 2011-10-26
JP5253578B2 (ja) 2013-07-31
CN101868473B (zh) 2012-12-26
EP2380896A4 (en) 2012-02-22

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