DK2407154T3 - Formuleringer af 14-epi-analoger af D-vitamin - Google Patents

Formuleringer af 14-epi-analoger af D-vitamin

Info

Publication number: DK2407154T3
Authority: DK; Denmark
Prior art keywords: vitamin; formulations; epi analogues; epi; analogues
Prior art date: 2010-07-15

Application number

DK11173836.5T

Other languages

English (en)

Inventor

Remi Delansorne

Original Assignee

Hybrigenics Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-07-15

Filing date

2011-07-13

Publication date

2013-03-04

2010-07-15 Priority claimed from US12/836,974 external-priority patent/US20120015913A1/en

2010-07-15 Priority claimed from EP10305783A external-priority patent/EP2407152A1/en

2011-07-13 Application filed by Hybrigenics Sa filed Critical Hybrigenics Sa

2013-03-04 Application granted granted Critical

2013-03-04 Publication of DK2407154T3 publication Critical patent/DK2407154T3/da

Links

229930003316 Vitamin D Natural products 0.000 title 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title 1
238000009472 formulation Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
235000019166 vitamin D Nutrition 0.000 title 1
239000011710 vitamin D Substances 0.000 title 1
150000003710 vitamin D derivatives Chemical class 0.000 title 1
229940046008 vitamin d Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Obesity (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Neurosurgery (AREA)
Nutrition Science (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Transplantation (AREA)
Neurology (AREA)
Dispersion Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK11173836.5T 2010-07-15 2011-07-13 Formuleringer af 14-epi-analoger af D-vitamin DK2407154T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12/836,974 US20120015913A1 (en)	2010-07-15	2010-07-15	Formulations of 14-EPI-Analogues of Vitamin D
EP10305783A EP2407152A1 (en)	2010-07-15	2010-07-15	Formulations of 14-epi-analogues of vitamin D

Publications (1)

Publication Number	Publication Date
DK2407154T3 true DK2407154T3 (da)	2013-03-04

Family

ID=44281019

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK11173860.5T DK2407155T3 (da)	2010-07-15	2011-07-13	Formuleringer af inecalcitol
DK11173836.5T DK2407154T3 (da)	2010-07-15	2011-07-13	Formuleringer af 14-epi-analoger af D-vitamin

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK11173860.5T DK2407155T3 (da)	2010-07-15	2011-07-13	Formuleringer af inecalcitol

Country Status (18)

Country	Link
EP (2)	EP2407155B1 (da)
JP (2)	JP5836373B2 (da)
KR (2)	KR101821440B1 (da)
CN (2)	CN103096877B (da)
AU (2)	AU2011278352B2 (da)
BR (2)	BR112013000941A2 (da)
CA (2)	CA2805198C (da)
DK (2)	DK2407155T3 (da)
ES (2)	ES2398640T3 (da)
HR (2)	HRP20130093T1 (da)
IL (2)	IL224191A (da)
MX (1)	MX2013000539A (da)
NZ (2)	NZ606679A (da)
PL (2)	PL2407154T3 (da)
PT (2)	PT2407154E (da)
SG (2)	SG187072A1 (da)
SI (2)	SI2407154T1 (da)
WO (3)	WO2012007512A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20120015913A1 (en)	2010-07-15	2012-01-19	Delansorne Remi	Formulations of 14-EPI-Analogues of Vitamin D
EP2407155B1 (en) *	2010-07-15	2012-12-26	Hybrigenics S.A.	Formulations of inecalcitol
WO2014063105A1 (en) *	2012-10-19	2014-04-24	Celus Pharmaceuticals, Inc.	Vitamin d analogues for the treatment of a neurological disorder
EP3157533A1 (en) *	2014-06-19	2017-04-26	INSERM (Institut National de la Santé et de la Recherche Médicale)	Composition comprising a combination of dna methylation inhibitor and a vitamin d receptor agonist for the treatment of drug resistant cancer or for the prevention of tumor relapse
US11406616B2 (en) *	2016-06-08	2022-08-09	Sunregen Healthcare Ag	Lipids with odd number of carbon atoms and their use as pharmaceutical composition or nutritional supplement

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2153491C2 (ru)	1993-07-09	2000-07-27	Лаборатуар Терамекс С.А.	Аналоги витамина d, соединения, способы их получения и фармацевтическая композиция
JPH10111593A (ja) *	1996-10-04	1998-04-28	Asahi Optical Co Ltd	複写機の変倍光学装置
US5936105A (en)	1997-06-13	1999-08-10	Tetrionics, Inc.	14-EPI-19-nor-vitamin D compounds and methods
US6248363B1 (en) *	1999-11-23	2001-06-19	Lipocine, Inc.	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6309663B1 (en) *	1999-08-17	2001-10-30	Lipocine Inc.	Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
GB0305332D0 (en)	2003-03-10	2003-04-09	Leuven K U Res & Dev	Biological evaluation of novel vitamin D analogues
US20050020546A1 (en) *	2003-06-11	2005-01-27	Novacea, Inc.	Pharmaceutical compositions comprising active vitamin D compounds
SG110107A1 (en)	2003-09-24	2005-04-28	Bioxell Spa	Compound and use in treatment
GB0423091D0 (en) *	2004-10-19	2004-11-17	Leuven K U Res & Dev	Bioactive vitamin d analogues
US20070093458A1 (en) *	2005-07-18	2007-04-26	Anchel Schwartz	Preparation of paricalcitol and crystalline forms thereof
US20080145411A1 (en) *	2006-10-06	2008-06-19	Kaneka Corporation	Composition of high absorbability for oral administration comprising oxidized coenzyme q10
JP2010111593A (ja) *	2008-11-04	2010-05-20	Teijin Pharma Ltd	１４−エピ−１９−ノルプレビタミンｄ３誘導体
KR101845320B1 (ko) *	2009-05-20	2018-04-04	하이브리제닉스 에스에이	이네칼시톨의 신규한 치료 용도
EP2407155B1 (en) *	2010-07-15	2012-12-26	Hybrigenics S.A.	Formulations of inecalcitol

2011
- 2011-07-13 EP EP11173860A patent/EP2407155B1/en not_active Not-in-force
- 2011-07-13 KR KR1020137003059A patent/KR101821440B1/ko not_active Expired - Fee Related
- 2011-07-13 NZ NZ606679A patent/NZ606679A/en not_active IP Right Cessation
- 2011-07-13 CN CN201180043277.7A patent/CN103096877B/zh not_active Expired - Fee Related
- 2011-07-13 JP JP2013519097A patent/JP5836373B2/ja not_active Expired - Fee Related
- 2011-07-13 CN CN2011800432762A patent/CN103096876A/zh active Pending
- 2011-07-13 MX MX2013000539A patent/MX2013000539A/es active IP Right Grant
- 2011-07-13 PL PL11173836T patent/PL2407154T3/pl unknown
- 2011-07-13 DK DK11173860.5T patent/DK2407155T3/da active
- 2011-07-13 EP EP11173836A patent/EP2407154B1/en not_active Not-in-force
- 2011-07-13 SG SG2013002910A patent/SG187072A1/en unknown
- 2011-07-13 PL PL11173860T patent/PL2407155T3/pl unknown
- 2011-07-13 NZ NZ606678A patent/NZ606678A/en not_active IP Right Cessation
- 2011-07-13 JP JP2013519093A patent/JP5836372B2/ja not_active Expired - Fee Related
- 2011-07-13 SG SG2013002902A patent/SG187071A1/en unknown
- 2011-07-13 DK DK11173836.5T patent/DK2407154T3/da active
- 2011-07-13 CA CA2805198A patent/CA2805198C/en not_active Expired - Fee Related
- 2011-07-13 KR KR1020137003060A patent/KR101821441B1/ko not_active Expired - Fee Related
- 2011-07-13 ES ES11173836T patent/ES2398640T3/es active Active
- 2011-07-13 WO PCT/EP2011/061973 patent/WO2012007512A1/en not_active Ceased
- 2011-07-13 ES ES11173860T patent/ES2401715T3/es active Active
- 2011-07-13 CA CA2805203A patent/CA2805203A1/en not_active Abandoned
- 2011-07-13 BR BR112013000941A patent/BR112013000941A2/pt not_active Application Discontinuation
- 2011-07-13 WO PCT/EP2011/061984 patent/WO2012007517A1/en not_active Ceased
- 2011-07-13 SI SI201130012T patent/SI2407154T1/sl unknown
- 2011-07-13 AU AU2011278352A patent/AU2011278352B2/en not_active Ceased
- 2011-07-13 AU AU2011278346A patent/AU2011278346B2/en not_active Ceased
- 2011-07-13 PT PT111738365T patent/PT2407154E/pt unknown
- 2011-07-13 SI SI201130021T patent/SI2407155T1/sl unknown
- 2011-07-13 PT PT111738605T patent/PT2407155E/pt unknown
- 2011-07-13 BR BR112013000930A patent/BR112013000930A2/pt not_active Application Discontinuation
- 2011-07-15 WO PCT/EP2011/062127 patent/WO2012007570A2/en not_active Ceased
2013
- 2013-01-13 IL IL224191A patent/IL224191A/en active IP Right Grant
- 2013-01-13 IL IL224192A patent/IL224192A/en active IP Right Grant
- 2013-02-04 HR HRP20130093AT patent/HRP20130093T1/hr unknown
- 2013-03-19 HR HRP20130237AT patent/HRP20130237T1/hr unknown

Also Published As

Publication number	Publication date
BR112013000941A2 (pt)	2017-10-31
RU2013106492A (ru)	2014-08-20
DK2407155T3 (da)	2013-04-02
JP2013531024A (ja)	2013-08-01
NZ606678A (en)	2014-11-28
ES2398640T3 (es)	2013-03-20
HRP20130093T1 (hr)	2013-02-28
SI2407154T1 (sl)	2013-03-29
KR20130103709A (ko)	2013-09-24
CA2805203A1 (en)	2012-01-19
KR20130089249A (ko)	2013-08-09
CA2805198C (en)	2018-07-31
JP5836372B2 (ja)	2015-12-24
JP2013531023A (ja)	2013-08-01
SG187071A1 (en)	2013-02-28
WO2012007512A1 (en)	2012-01-19
IL224191A (en)	2016-03-31
AU2011278352A1 (en)	2013-03-07
HRP20130237T1 (hr)	2013-04-30
CN103096877A (zh)	2013-05-08
SI2407155T1 (sl)	2013-04-30
WO2012007570A3 (en)	2012-05-24
AU2011278352B2 (en)	2016-07-21
EP2407155A1 (en)	2012-01-18
PT2407154E (pt)	2013-02-15
CN103096876A (zh)	2013-05-08
RU2013106493A (ru)	2014-08-20
KR101821440B1 (ko)	2018-01-23
BR112013000930A2 (pt)	2017-10-31
SG187072A1 (en)	2013-03-28
JP5836373B2 (ja)	2015-12-24
IL224192A (en)	2016-02-29
ES2401715T3 (es)	2013-04-23
NZ606679A (en)	2014-07-25
KR101821441B1 (ko)	2018-01-23
PL2407155T3 (pl)	2013-05-31
AU2011278346B2 (en)	2016-04-07
CA2805198A1 (en)	2012-01-19
WO2012007517A1 (en)	2012-01-19
AU2011278346A1 (en)	2013-03-07
MX2013000539A (es)	2013-04-11
EP2407154A1 (en)	2012-01-18
WO2012007570A2 (en)	2012-01-19
EP2407154B1 (en)	2012-11-07
EP2407155B1 (en)	2012-12-26
PT2407155E (pt)	2013-04-03
CN103096877B (zh)	2017-09-22
PL2407154T3 (pl)	2013-04-30

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