DK246786D0 - Laegemiddel indeholdende vaevs-plasminogen-aktivator - Google Patents

Laegemiddel indeholdende vaevs-plasminogen-aktivator

Info

Publication number
DK246786D0
DK246786D0 DK246786A DK246786A DK246786D0 DK 246786 D0 DK246786 D0 DK 246786D0 DK 246786 A DK246786 A DK 246786A DK 246786 A DK246786 A DK 246786A DK 246786 D0 DK246786 D0 DK 246786D0
Authority
DK
Denmark
Prior art keywords
plasminogen activator
containing pharmaceutical
pharmaceuticals containing
pharmaceuticals
pharmaceutical
Prior art date
Application number
DK246786A
Other languages
English (en)
Other versions
DK163173C (da
DK163173B (da
DK246786A (da
Inventor
Michael Denis Johnston
Henry Berger
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858513358A external-priority patent/GB8513358D0/en
Priority claimed from GB858521705A external-priority patent/GB8521705D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK246786D0 publication Critical patent/DK246786D0/da
Publication of DK246786A publication Critical patent/DK246786A/da
Publication of DK163173B publication Critical patent/DK163173B/da
Application granted granted Critical
Publication of DK163173C publication Critical patent/DK163173C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK246786A 1985-05-28 1986-05-27 Fremgangsmaade til fremstilling af et lyofiliseret farmaceutisk praeparat af vaevs-plasminogenaktivator (t-pa) DK163173C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB858513358A GB8513358D0 (en) 1985-05-28 1985-05-28 Formulation
GB8513358 1985-05-28
GB858521705A GB8521705D0 (en) 1985-08-31 1985-08-31 Formulation
GB8521705 1985-08-31

Publications (4)

Publication Number Publication Date
DK246786D0 true DK246786D0 (da) 1986-05-27
DK246786A DK246786A (da) 1986-11-29
DK163173B DK163173B (da) 1992-02-03
DK163173C DK163173C (da) 1992-06-22

Family

ID=26289290

Family Applications (1)

Application Number Title Priority Date Filing Date
DK246786A DK163173C (da) 1985-05-28 1986-05-27 Fremgangsmaade til fremstilling af et lyofiliseret farmaceutisk praeparat af vaevs-plasminogenaktivator (t-pa)

Country Status (22)

Country Link
US (2) US4929444A (da)
JP (1) JPH0759517B2 (da)
AU (1) AU567236B2 (da)
BE (1) BE904830A (da)
CA (1) CA1300008C (da)
CH (1) CH665356A5 (da)
DE (1) DE3617752A1 (da)
DK (1) DK163173C (da)
ES (2) ES8800601A1 (da)
FI (1) FI85335C (da)
FR (1) FR2583984B1 (da)
GB (1) GB2176702B (da)
GR (1) GR861366B (da)
HU (1) HU195733B (da)
IL (1) IL78938A (da)
IT (1) IT1191926B (da)
LU (1) LU86444A1 (da)
NL (1) NL8601355A (da)
NO (1) NO171345C (da)
NZ (1) NZ216307A (da)
PT (1) PT82646B (da)
SE (1) SE462016B (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU569429B2 (en) * 1985-05-28 1988-01-28 Wellcome Foundation Limited, The Aqueous acidic tissue plasminogen activator parenternal formulation
ZW14486A1 (en) * 1985-07-29 1986-10-22 Smithkline Beckman Corp Pharmaceutical dosage unit
US4777043A (en) * 1985-12-17 1988-10-11 Genentech, Inc. Stabilized human tissue plasminogen activator compositions
US5034225A (en) * 1985-12-17 1991-07-23 Genentech Inc. Stabilized human tissue plasminogen activator compositions
US4976959A (en) * 1986-05-12 1990-12-11 Burroughs Wellcome Co. T-PA and SOD in limiting tissue damage
AU600724B2 (en) * 1986-05-12 1990-08-23 Boehringer Ingelheim International Gmbh Novel combination
GB8619098D0 (en) * 1986-08-05 1986-09-17 Wellcome Found Combination
US5270198A (en) * 1988-05-20 1993-12-14 Genentech, Inc. DNA molecules encoding variants of tissue plasminogen activators, vectors, and host cells
US5342616A (en) * 1988-06-20 1994-08-30 The Wellcome Foundation Limited Method of administering tissue plasminogen activator
US5262170A (en) * 1988-09-02 1993-11-16 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
DE3835350A1 (de) * 1988-10-17 1990-04-19 Boehringer Mannheim Gmbh Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern
US4980165A (en) * 1989-01-27 1990-12-25 Genetics Institute, Inc. Pharmaceutical formulations of plasminogen activator proteins
DE3942142A1 (de) * 1989-12-20 1991-06-27 Boehringer Mannheim Gmbh Stabilisierung von glykosyliertem t-pa
WO1992011866A1 (en) * 1991-01-14 1992-07-23 Duke University LAMININ SEQUENCE AS tPA ACTIVATOR
DK0643772T3 (da) * 1992-06-03 1998-02-02 Genentech Inc Glycosyleringsvarianter af vævsplasminogenaktivator med forbedrede terapeutiske egenskaber
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
CN1202932A (zh) * 1995-10-23 1998-12-23 儿童医学中心公司 治疗用抗血管生成的组合物和方法
EP0869970B1 (en) * 1995-12-13 2004-03-24 The Children's Medical Center Corporation Endothelial cell proliferation inhibitor and its use
DE69719265T2 (de) * 1996-09-06 2003-12-04 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Kumamoto Medizinische Zusammensetzung die Gewebeplasminogenaktivator und Nikotinamid enthält
CN1553811A (zh) * 2001-09-07 2004-12-08 ӡ�����Ƽ��ɷ����޹�˾ 人组织尿激酶类型纤溶酶原激活物制剂
US20040091465A1 (en) * 2002-06-26 2004-05-13 Zachary Yim Therapeutic antiangiogenic compositions and methods
CA2528577C (en) * 2003-06-20 2012-08-07 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US7491263B2 (en) * 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
PT1879599E (pt) * 2005-04-20 2014-01-23 Hutchinson Fred Cancer Res Métodos, composições e artigos de fabrico para aumentar a capacidade de sobrevivência de células, tecidos, órgãos, e organismos

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998947A (en) * 1973-11-30 1976-12-21 Pierre Fabre S.A. Process for obtaining a plasminogen activator
FR2252842B1 (da) * 1973-12-03 1977-11-04 Fabre Sa Pierre
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
US4766075A (en) * 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
EP0124613B1 (en) * 1982-10-29 1992-12-30 MITSUI TOATSU CHEMICALS, Inc. Novel plasminogen activator derived from human kidneys, process for its preparation, and thrombolytic drug containing the same
AU554862B2 (en) * 1982-12-14 1986-09-04 Implico B.V. Plasminogen activator isolated by affinity chromatography
NZ206699A (en) * 1982-12-30 1989-08-29 Bio Response Inc Process for the production of serum independent cell lines
JPS59196824A (ja) * 1983-04-21 1984-11-08 Kowa Co 吸着防止剤
DE3584902D1 (de) * 1984-02-29 1992-01-30 Asahi Chemical Ind Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
DE3439980A1 (de) * 1984-11-02 1986-05-07 Behringwerke Ag, 3550 Marburg Verfahren zur reinigung sowie pasteurisierung von urokinase
EP0201153A3 (en) * 1985-02-09 1987-10-07 Beecham Group Plc Modified enzyme and process for its preparation
GB8513358D0 (en) * 1985-05-28 1985-07-03 Wellcome Found Formulation
ZW14486A1 (en) * 1985-07-29 1986-10-22 Smithkline Beckman Corp Pharmaceutical dosage unit
JPH0672105B2 (ja) * 1985-10-02 1994-09-14 持田製薬株式会社 血栓溶解剤及びその製法

Also Published As

Publication number Publication date
HU195733B (en) 1988-07-28
ES8802439A1 (es) 1988-06-01
NL8601355A (nl) 1986-12-16
AU5796486A (en) 1986-12-04
FR2583984B1 (fr) 1989-06-02
SE462016B (sv) 1990-04-30
AU567236B2 (en) 1987-11-12
HUT41638A (en) 1987-05-28
DK163173C (da) 1992-06-22
DE3617752A1 (de) 1986-12-04
CA1300008C (en) 1992-05-05
GR861366B (en) 1986-09-29
DK163173B (da) 1992-02-03
CH665356A5 (de) 1988-05-13
NO171345C (no) 1993-03-03
NO862096L (no) 1986-12-01
IL78938A0 (en) 1986-09-30
SE8602405L (sv) 1986-11-29
NO171345B (no) 1992-11-23
GB2176702A (en) 1987-01-07
NZ216307A (en) 1989-10-27
ES555353A0 (es) 1987-11-16
PT82646B (pt) 1989-01-30
US4929444A (en) 1990-05-29
ES8800601A1 (es) 1987-11-16
GB8612780D0 (en) 1986-07-02
GB2176702B (en) 1989-07-05
BE904830A (fr) 1986-11-27
IT1191926B (it) 1988-03-31
ES557374A0 (es) 1988-06-01
IL78938A (en) 1993-02-21
FI85335C (fi) 1992-04-10
LU86444A1 (fr) 1986-12-05
FI862227A0 (fi) 1986-05-27
DE3617752C2 (da) 1988-06-30
JPH06183995A (ja) 1994-07-05
SE8602405D0 (sv) 1986-05-27
JPH0759517B2 (ja) 1995-06-28
US4968617A (en) 1990-11-06
FI862227L (fi) 1986-11-29
FI85335B (fi) 1991-12-31
DK246786A (da) 1986-11-29
FR2583984A1 (fr) 1987-01-02
IT8648065A0 (it) 1986-05-27
PT82646A (en) 1986-06-01

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Legal Events

Date Code Title Description
PBP Patent lapsed