NO862096L - Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator. - Google Patents

Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator.

Info

Publication number: NO862096L
Authority: NO; Norway
Prior art keywords: procedure; preparation; pharmaceutical preparations; plasminogen activator; tissue plasminogen
Prior art date: 1985-05-28

Application number

NO862096A

Other languages

English (en)

Other versions

NO171345C (no

NO171345B (no

Inventor

Michael Denis Johnston

Henry Berger

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-28

Filing date

1986-05-27

Publication date

1986-12-01

1985-05-28 Priority claimed from GB858513358A external-priority patent/GB8513358D0/en

1985-08-31 Priority claimed from GB858521705A external-priority patent/GB8521705D0/en

1986-05-27 Application filed by Wellcome Found filed Critical Wellcome Found

1986-12-01 Publication of NO862096L publication Critical patent/NO862096L/no

1992-11-23 Publication of NO171345B publication Critical patent/NO171345B/no

1993-03-03 Publication of NO171345C publication Critical patent/NO171345C/no

Links

102000003978 Tissue Plasminogen Activator Human genes 0.000 title 1
108090000373 Tissue Plasminogen Activator Proteins 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
229960000187 tissue plasminogen activator Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Enzymes And Modification Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

NO862096A 1985-05-28 1986-05-27 Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator NO171345C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB858513358A GB8513358D0 (en)	1985-05-28	1985-05-28	Formulation
GB858521705A GB8521705D0 (en)	1985-08-31	1985-08-31	Formulation

Publications (3)

Publication Number	Publication Date
NO862096L true NO862096L (no)	1986-12-01
NO171345B NO171345B (no)	1992-11-23
NO171345C NO171345C (no)	1993-03-03

Family

ID=26289290

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO862096A NO171345C (no)	1985-05-28	1986-05-27	Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator

Country Status (22)

Country	Link
US (2)	US4929444A (no)
JP (1)	JPH0759517B2 (no)
AU (1)	AU567236B2 (no)
BE (1)	BE904830A (no)
CA (1)	CA1300008C (no)
CH (1)	CH665356A5 (no)
DE (1)	DE3617752A1 (no)
DK (1)	DK163173C (no)
ES (2)	ES8800601A1 (no)
FI (1)	FI85335C (no)
FR (1)	FR2583984B1 (no)
GB (1)	GB2176702B (no)
GR (1)	GR861366B (no)
HU (1)	HU195733B (no)
IL (1)	IL78938A (no)
IT (1)	IT1191926B (no)
LU (1)	LU86444A1 (no)
NL (1)	NL8601355A (no)
NO (1)	NO171345C (no)
NZ (1)	NZ216307A (no)
PT (1)	PT82646B (no)
SE (1)	SE462016B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU569429B2 (en) *	1985-05-28	1988-01-28	Wellcome Foundation Limited, The	Aqueous acidic tissue plasminogen activator parenternal formulation
ZW14486A1 (en) *	1985-07-29	1986-10-22	Smithkline Beckman Corp	Pharmaceutical dosage unit
US4777043A (en) *	1985-12-17	1988-10-11	Genentech, Inc.	Stabilized human tissue plasminogen activator compositions
US5034225A (en) *	1985-12-17	1991-07-23	Genentech Inc.	Stabilized human tissue plasminogen activator compositions
US4976959A (en) *	1986-05-12	1990-12-11	Burroughs Wellcome Co.	T-PA and SOD in limiting tissue damage
AU600724B2 (en) *	1986-05-12	1990-08-23	Boehringer Ingelheim International Gmbh	Novel combination
GB8619098D0 (en) *	1986-08-05	1986-09-17	Wellcome Found	Combination
US5270198A (en) *	1988-05-20	1993-12-14	Genentech, Inc.	DNA molecules encoding variants of tissue plasminogen activators, vectors, and host cells
US5342616A (en) *	1988-06-20	1994-08-30	The Wellcome Foundation Limited	Method of administering tissue plasminogen activator
US5262170A (en) *	1988-09-02	1993-11-16	Genentech, Inc.	Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US5714145A (en) *	1988-09-02	1998-02-03	Genentech, Inc.	Tissue plasminogen activator having zymogenic or fibrin specific properties
DE3835350A1 (de) *	1988-10-17	1990-04-19	Boehringer Mannheim Gmbh	Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern
US4980165A (en) *	1989-01-27	1990-12-25	Genetics Institute, Inc.	Pharmaceutical formulations of plasminogen activator proteins
DE3942142A1 (de) *	1989-12-20	1991-06-27	Boehringer Mannheim Gmbh	Stabilisierung von glykosyliertem t-pa
WO1992011866A1 (en) *	1991-01-14	1992-07-23	Duke University	LAMININ SEQUENCE AS tPA ACTIVATOR
DK0643772T3 (da) *	1992-06-03	1998-02-02	Genentech Inc	Glycosyleringsvarianter af vævsplasminogenaktivator med forbedrede terapeutiske egenskaber
US6346510B1 (en)	1995-10-23	2002-02-12	The Children's Medical Center Corporation	Therapeutic antiangiogenic endostatin compositions
CN1202932A (zh) *	1995-10-23	1998-12-23	儿童医学中心公司	治疗用抗血管生成的组合物和方法
EP0869970B1 (en) *	1995-12-13	2004-03-24	The Children's Medical Center Corporation	Endothelial cell proliferation inhibitor and its use
DE69719265T2 (de) *	1996-09-06	2003-12-04	Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Kumamoto	Medizinische Zusammensetzung die Gewebeplasminogenaktivator und Nikotinamid enthält
CN1553811A (zh) *	2001-09-07	2004-12-08	ӡ��Ƽ��ɷ��޹�˾	人组织尿激酶类型纤溶酶原激活物制剂
US20040091465A1 (en) *	2002-06-26	2004-05-13	Zachary Yim	Therapeutic antiangiogenic compositions and methods
CA2528577C (en) *	2003-06-20	2012-08-07	Illumina, Inc.	Methods and compositions for whole genome amplification and genotyping
US7491263B2 (en) *	2004-04-05	2009-02-17	Technology Innovation, Llc	Storage assembly
PT1879599E (pt) *	2005-04-20	2014-01-23	Hutchinson Fred Cancer Res	Métodos, composições e artigos de fabrico para aumentar a capacidade de sobrevivência de células, tecidos, órgãos, e organismos

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3998947A (en) *	1973-11-30	1976-12-21	Pierre Fabre S.A.	Process for obtaining a plasminogen activator
FR2252842B1 (no) *	1973-12-03	1977-11-04	Fabre Sa Pierre
DE3015699C2 (de) *	1979-04-26	1982-07-15	Asahi Kasei Kogyo K.K., Osaka	Herstellung eines Plasminogen-Aktivators
US4766075A (en) *	1982-07-14	1988-08-23	Genentech, Inc.	Human tissue plasminogen activator
JPS5951220A (ja) *	1982-08-02	1984-03-24	Asahi Chem Ind Co Ltd	新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
EP0124613B1 (en) *	1982-10-29	1992-12-30	MITSUI TOATSU CHEMICALS, Inc.	Novel plasminogen activator derived from human kidneys, process for its preparation, and thrombolytic drug containing the same
AU554862B2 (en) *	1982-12-14	1986-09-04	Implico B.V.	Plasminogen activator isolated by affinity chromatography
NZ206699A (en) *	1982-12-30	1989-08-29	Bio Response Inc	Process for the production of serum independent cell lines
JPS59196824A (ja) *	1983-04-21	1984-11-08	Kowa Co	吸着防止剤
DE3584902D1 (de) *	1984-02-29	1992-01-30	Asahi Chemical Ind	Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
DE3439980A1 (de) *	1984-11-02	1986-05-07	Behringwerke Ag, 3550 Marburg	Verfahren zur reinigung sowie pasteurisierung von urokinase
EP0201153A3 (en) *	1985-02-09	1987-10-07	Beecham Group Plc	Modified enzyme and process for its preparation
GB8513358D0 (en) *	1985-05-28	1985-07-03	Wellcome Found	Formulation
ZW14486A1 (en) *	1985-07-29	1986-10-22	Smithkline Beckman Corp	Pharmaceutical dosage unit
JPH0672105B2 (ja) *	1985-10-02	1994-09-14	持田製薬株式会社	血栓溶解剤及びその製法

1986
- 1986-05-13 US US06/862,817 patent/US4929444A/en not_active Expired - Lifetime
- 1986-05-27 NZ NZ216307A patent/NZ216307A/xx unknown
- 1986-05-27 PT PT82646A patent/PT82646B/pt not_active IP Right Cessation
- 1986-05-27 SE SE8602405A patent/SE462016B/sv not_active IP Right Cessation
- 1986-05-27 NO NO862096A patent/NO171345C/no unknown
- 1986-05-27 LU LU86444A patent/LU86444A1/fr unknown
- 1986-05-27 FR FR8607552A patent/FR2583984B1/fr not_active Expired
- 1986-05-27 CA CA000510097A patent/CA1300008C/en not_active Expired - Fee Related
- 1986-05-27 CH CH2126/86A patent/CH665356A5/de not_active IP Right Cessation
- 1986-05-27 FI FI862227A patent/FI85335C/fi not_active IP Right Cessation
- 1986-05-27 IT IT48065/86A patent/IT1191926B/it active
- 1986-05-27 DK DK246786A patent/DK163173C/da not_active IP Right Cessation
- 1986-05-27 AU AU57964/86A patent/AU567236B2/en not_active Ceased
- 1986-05-27 HU HU862234A patent/HU195733B/hu not_active IP Right Cessation
- 1986-05-27 NL NL8601355A patent/NL8601355A/nl not_active Application Discontinuation
- 1986-05-27 GB GB8612780A patent/GB2176702B/en not_active Expired
- 1986-05-27 DE DE19863617752 patent/DE3617752A1/de active Granted
- 1986-05-27 GR GR861366A patent/GR861366B/el unknown
- 1986-05-27 IL IL78938A patent/IL78938A/xx not_active IP Right Cessation
- 1986-05-27 BE BE0/216711A patent/BE904830A/fr not_active IP Right Cessation
- 1986-05-27 ES ES555353A patent/ES8800601A1/es not_active Expired
1987
- 1987-02-10 ES ES557374A patent/ES8802439A1/es not_active Expired
1988
- 1988-07-29 US US07/226,422 patent/US4968617A/en not_active Expired - Lifetime
1993
- 1993-09-16 JP JP5230427A patent/JPH0759517B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
HU195733B (en)	1988-07-28
ES8802439A1 (es)	1988-06-01
NL8601355A (nl)	1986-12-16
DK246786D0 (da)	1986-05-27
AU5796486A (en)	1986-12-04
FR2583984B1 (fr)	1989-06-02
SE462016B (sv)	1990-04-30
AU567236B2 (en)	1987-11-12
HUT41638A (en)	1987-05-28
DK163173C (da)	1992-06-22
DE3617752A1 (de)	1986-12-04
CA1300008C (en)	1992-05-05
GR861366B (en)	1986-09-29
DK163173B (da)	1992-02-03
CH665356A5 (de)	1988-05-13
NO171345C (no)	1993-03-03
IL78938A0 (en)	1986-09-30
SE8602405L (sv)	1986-11-29
NO171345B (no)	1992-11-23
GB2176702A (en)	1987-01-07
NZ216307A (en)	1989-10-27
ES555353A0 (es)	1987-11-16
PT82646B (pt)	1989-01-30
US4929444A (en)	1990-05-29
ES8800601A1 (es)	1987-11-16
GB8612780D0 (en)	1986-07-02
GB2176702B (en)	1989-07-05
BE904830A (fr)	1986-11-27
IT1191926B (it)	1988-03-31
ES557374A0 (es)	1988-06-01
IL78938A (en)	1993-02-21
FI85335C (fi)	1992-04-10
LU86444A1 (fr)	1986-12-05
FI862227A0 (fi)	1986-05-27
DE3617752C2 (no)	1988-06-30
JPH06183995A (ja)	1994-07-05
SE8602405D0 (sv)	1986-05-27
JPH0759517B2 (ja)	1995-06-28
US4968617A (en)	1990-11-06
FI862227L (fi)	1986-11-29
FI85335B (fi)	1991-12-31
DK246786A (da)	1986-11-29
FR2583984A1 (fr)	1987-01-02
IT8648065A0 (it)	1986-05-27
PT82646A (en)	1986-06-01

Publication	Publication Date	Title
NO862096L (no)	1986-12-01	Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator.
NO171344C (no)	1993-03-03	Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator
NO864126D0 (no)	1986-10-16	Fremgangsmaate for fremstilling av terapeutisk aktive pyridon-derivater.
NO854194L (no)	1986-04-23	Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende antracyklinglykosider.
NO163406C (no)	1990-05-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinolinonderivater.
NO862477D0 (no)	1986-06-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-arylimidazol-derivater.
NO871266D0 (no)	1987-03-26	Fremgangsmaate for fremstilling av terapeutisk aktive kinazolin-derivater.
NO169493C (no)	1992-07-01	Analogifremgangsmaate for fremstilling av terapeutisk aktive peptid-derivater
IT1235532B (it)	1992-09-09	Composti carbossiammidici, procedimenti per la preparazione dei medesimi e composizione farmaceutica contenente i medesimi
NO870526L (no)	1987-08-13	Fremgangsmaate for fremstilling av terapeutisk aktive dikloranilin-derivater.
NO864879L (no)	1987-06-09	Fremgangsmaate for fremstilling av terapeutisk aktive tiazolforbindelser.
NO874032L (no)	1988-03-28	Fremgangsmaate for fremstilling av terapeutisk aktive catecholderivater.
NO167026C (no)	1991-09-25	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater
NO872551D0 (no)	1987-06-18	Fremgangsmaate for fremstilling av farmasoeytiske preparater
NO864674D0 (no)	1986-11-21	Fremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser.
NO862373D0 (no)	1986-06-13	Fremgangsmaate for fremstilling av terapeutisk aktive tienopyridoner.
NO864130D0 (no)	1986-10-16	Fremgangsmaate for fremstilling av terapeutisk aktive karboksamid-derivater.
NO875488L (no)	1988-07-01	Fremgangsmaate for fremstilling av terapeutisk aktive alkansulfonanilid-derivater.
NO862372D0 (no)	1986-06-13	Fremgangsmaate for fremstilling av terapeutisk aktive kinolonderivater.
NO165069C (no)	1990-12-19	Analogifremgangsmaate for fremstilling av terapeutisk aktive cyklopentyletere.
NO874200D0 (no)	1987-10-07	Fremgangsmaate for fremstilling av farmasoeytiske preparater
NO900297D0 (no)	1990-01-22	Fremgangsmaate for fremstilling av vaeskeformige preparaterinneholdende piperidinoalkanolderivater.
NO164899C (no)	1990-11-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazolylindolforbindelser.
NO864101L (no)	1987-04-21	Fremgangsmaate for fremstilling av terapeutisk aktive dikloranilinderivater.
NO873423D0 (no)	1987-08-14	Fremgangsmaate for fremstilling av farmasoeytiske preparater