DK249479A - Fremgangsmaade til fremstilling af prostaglandinanaloge - Google Patents

Fremgangsmaade til fremstilling af prostaglandinanaloge

Info

Publication number
DK249479A
DK249479A DK249479A DK249479A DK249479A DK 249479 A DK249479 A DK 249479A DK 249479 A DK249479 A DK 249479A DK 249479 A DK249479 A DK 249479A DK 249479 A DK249479 A DK 249479A
Authority
DK
Denmark
Prior art keywords
sub
alkyl
prostagland
analog
procedure
Prior art date
Application number
DK249479A
Other languages
English (en)
Inventor
F Cassidy
A C Coudie
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of DK249479A publication Critical patent/DK249479A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86Oxygen and sulfur atoms, e.g. thiohydantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK249479A 1978-06-15 1979-06-14 Fremgangsmaade til fremstilling af prostaglandinanaloge DK249479A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7827019 1978-06-15

Publications (1)

Publication Number Publication Date
DK249479A true DK249479A (da) 1979-12-16

Family

ID=10497983

Family Applications (1)

Application Number Title Priority Date Filing Date
DK249479A DK249479A (da) 1978-06-15 1979-06-14 Fremgangsmaade til fremstilling af prostaglandinanaloge

Country Status (12)

Country Link
US (1) US4241074A (da)
EP (1) EP0006353B1 (da)
JP (1) JPS554388A (da)
AT (1) ATE1422T1 (da)
AU (1) AU4778279A (da)
DE (1) DE2963476D1 (da)
DK (1) DK249479A (da)
ES (1) ES481603A1 (da)
IL (1) IL57505A0 (da)
NO (1) NO791979L (da)
PT (1) PT69750A (da)
ZA (1) ZA792977B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0020039A1 (en) * 1979-05-23 1980-12-10 Beecham Group Plc Imidazole derivatives, their preparation and their pharmaceutical compositions
US4496577A (en) * 1983-10-05 1985-01-29 Syntex (U.S.A.) Inc. Imidazolidinone prostaglandins, compositions and use
GB8417863D0 (en) * 1984-07-13 1984-08-15 Lucas Ind Plc Fuel pumping apparatus
US4746755A (en) * 1986-05-06 1988-05-24 The Dow Chemical Company Preparation of hydrantoic acids and hydantoins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2323193A1 (de) * 1972-05-10 1973-11-22 Du Pont Pyrazolidinone
DE2451160A1 (de) * 1973-10-30 1975-05-07 Du Pont 3-pyrazolidinone und pyrazolidine
CH645631A5 (en) * 1976-06-03 1984-10-15 Wellcome Found Process for the preparation of hydantoin derivatives
GB1598073A (en) * 1976-12-18 1981-09-16 Beecham Group Ltd 8,10,12-triazaprostaglandins
US4147796A (en) * 1976-12-18 1979-04-03 Beecham Group Limited 1-(3-Hydroxyalk-1-yl)-5-(carboxyalkyl)hydantoin derivatives
IL53559A0 (en) * 1976-12-18 1978-03-10 Beecham Group Ltd Novel prostaglandin analogues their preparation and pharmaceutical compositions containing them
IE48747B1 (en) * 1977-09-05 1985-05-15 Wellcome Found Hydantoin derivatives

Also Published As

Publication number Publication date
DE2963476D1 (en) 1982-09-30
ZA792977B (en) 1980-06-25
EP0006353B1 (en) 1982-08-04
ATE1422T1 (de) 1982-08-15
NO791979L (no) 1979-12-18
US4241074A (en) 1980-12-23
PT69750A (en) 1979-07-01
IL57505A0 (en) 1979-10-31
EP0006353A1 (en) 1980-01-09
JPS554388A (en) 1980-01-12
AU4778279A (en) 1979-12-20
ES481603A1 (es) 1980-06-16

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DK249479A (da) Fremgangsmaade til fremstilling af prostaglandinanaloge
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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment