DK252778A - Fremgangsmaade til fremstilling af somatostatinanaloge - Google Patents

Fremgangsmaade til fremstilling af somatostatinanaloge

Info

Publication number
DK252778A
DK252778A DK252778A DK252778A DK252778A DK 252778 A DK252778 A DK 252778A DK 252778 A DK252778 A DK 252778A DK 252778 A DK252778 A DK 252778A DK 252778 A DK252778 A DK 252778A
Authority
DK
Denmark
Prior art keywords
somatostatin analog
preparing
preparing somatostatin
analog
somatostatin
Prior art date
Application number
DK252778A
Other languages
English (en)
Inventor
D F Veber
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK252778A publication Critical patent/DK252778A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK252778A 1977-06-08 1978-06-07 Fremgangsmaade til fremstilling af somatostatinanaloge DK252778A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80467877A 1977-06-08 1977-06-08

Publications (1)

Publication Number Publication Date
DK252778A true DK252778A (da) 1978-12-09

Family

ID=25189555

Family Applications (1)

Application Number Title Priority Date Filing Date
DK252778A DK252778A (da) 1977-06-08 1978-06-07 Fremgangsmaade til fremstilling af somatostatinanaloge

Country Status (7)

Country Link
US (1) US4146612A (da)
EP (1) EP0000053B1 (da)
JP (1) JPS543085A (da)
DE (1) DE2860734D1 (da)
DK (1) DK252778A (da)
IE (1) IE47421B1 (da)
IT (1) IT1105131B (da)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK151034B (da) * 1977-09-28 1987-10-12 Ciba Geigy Ag Analogifremgangsmaade til fremstilling af somatostatinanaloge cyclopeptider eller fysiologisk taalelige syreadditionssalte eller komplekser deraf
DK152505B (da) * 1979-10-31 1988-03-07 Merck & Co Inc Analogifremgangsmaade til fremstilling af et somatostatin-analogt cyclisk hexapeptid

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190648A (en) * 1979-03-13 1980-02-26 Merck & Co., Inc. Peptides having somatostatin activity
DD155985A5 (de) * 1979-12-21 1982-07-21 Ciba Geigy Ag Verfahren zur herstellung cyclischr octapeptide
US4508711A (en) * 1983-04-18 1985-04-02 American Cyanamid Company Cyclic pentapeptide displaying somatostatin antagonism and method of treatment of mammals therewith
DE3822557C2 (de) * 1987-07-10 1998-07-02 Ciba Geigy Ag Arzneimittel, enthaltend Somatostatine
ZW11290A1 (en) * 1989-07-14 1990-10-31 Smithkline Beecham Corp Hemoregulatory peptides
WO1991007433A1 (en) * 1989-11-08 1991-05-30 Daicel Chemical Industries, Ltd. Peptide and process for preparing cyclic peptide
US6001960A (en) * 1992-09-01 1999-12-14 The Trustees Of The University Of Pennsylvania Synthetic somatostatin mimics
US5965694A (en) * 1992-09-01 1999-10-12 The Trustees Of The University Of Pennsylvania Somatostatin mimics and synthetic methods therefor
US5700905A (en) * 1992-09-01 1997-12-23 The Trustees Of The University Of Pennsylvania Synthetic somatostatin mimics
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
DE4342907A1 (de) * 1993-12-16 1995-06-22 Bayer Ag Neue cyclische Depsipeptide mit 18 Ringatomen und ihre Verwendung zur Bekämpfung von Endoparasiten
WO1996014810A2 (en) 1994-11-03 1996-05-23 The Saunders Group, Inc. Portable traction device
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
CA2289499C (en) * 1997-05-13 2010-02-23 Michael Anthony Cawthorne Somatostatin and somatostatin agonists for treating insulin insensitivity and syndrome x
EP0981364B1 (en) * 1997-05-13 2006-03-01 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Method and compositions for treating hyperlipidemia
CA2290592A1 (en) * 1997-05-13 1998-11-19 Michael Anthony Cawthorne Somatostatin and somatostatin agonists for decreasing body weight
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
US6171273B1 (en) 1999-08-06 2001-01-09 The Saunders Group, Inc. Self-seating occiput wedge system for applying a therapeutic traction force
NZ530007A (en) 2001-06-08 2006-02-24 Sod Conseils Rech Applic Somatostatin-dopamine chimeric analogues that retain both somatostatin and dopamine activity in vivo and display enhanced biological activity
US7189214B1 (en) * 2002-01-22 2007-03-13 The Saunders Group, Inc. Multi-axis cervical and lumbar traction table
US20040145462A1 (en) * 2003-01-29 2004-07-29 Honda Giken Kogyo Kabushiki Kaisha Variable electronic display apparatus for a vehicle, and method of using same
CA2523197C (en) 2003-04-22 2016-05-24 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Peptide vectors
WO2009150470A2 (en) 2008-06-12 2009-12-17 Syntaxin Limited Suppression of cancers
EP2310028B1 (en) 2008-06-12 2016-11-16 Ipsen Bioinnovation Limited Fusion proteins for use in the treatment of acromegaly
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US781610A (en) * 1904-01-11 1905-01-31 Winfield S Livengood Wagon-brake.
US3904594A (en) * 1973-07-02 1975-09-09 Salk Inst For Biological Studi Somatostatin and acylated des-(ala' 1', gly' 2') derivatives thereof
US3882098A (en) * 1974-01-03 1975-05-06 American Home Prod Synthesis of des-Ala{hu 1{b , Gly{hu 2{b , Asn{hu 5{b -SRIF and intermediates
DE2460469A1 (de) * 1974-12-20 1976-07-01 Hoechst Ag Neue peptide mit biologischer wirkung und verfahren zu ihrer herstellung
US3933784A (en) * 1975-01-27 1976-01-20 American Home Products Corporation Des-(ser13)-srif and intermediates
US4011182A (en) * 1975-03-21 1977-03-08 American Home Products Corporation Cyclic undecapeptide analogs of somatostatin and intermediates
CA1083143A (en) * 1976-01-02 1980-08-05 Nedumparambil A. Abraham Carba derivatives of somatostatin and process therefor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK151034B (da) * 1977-09-28 1987-10-12 Ciba Geigy Ag Analogifremgangsmaade til fremstilling af somatostatinanaloge cyclopeptider eller fysiologisk taalelige syreadditionssalte eller komplekser deraf
DK152505B (da) * 1979-10-31 1988-03-07 Merck & Co Inc Analogifremgangsmaade til fremstilling af et somatostatin-analogt cyclisk hexapeptid

Also Published As

Publication number Publication date
US4146612A (en) 1979-03-27
IT1105131B (it) 1985-10-28
IT7849736A0 (it) 1978-06-06
EP0000053A1 (en) 1978-12-20
DE2860734D1 (en) 1981-09-03
JPS543085A (en) 1979-01-11
EP0000053B1 (en) 1981-05-27
IE47421B1 (en) 1984-03-07
IE781151L (en) 1978-12-08

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