DK2542590T4 - Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner - Google Patents

Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner Download PDF

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Publication number
DK2542590T4
DK2542590T4 DK11751481.0T DK11751481T DK2542590T4 DK 2542590 T4 DK2542590 T4 DK 2542590T4 DK 11751481 T DK11751481 T DK 11751481T DK 2542590 T4 DK2542590 T4 DK 2542590T4
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compositions
procedure
fusion proteins
immunomodulatory antibodies
targeted immunomodulatory
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DK11751481.0T
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DK2542590T3 (da
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Atul Bedi
Rajani Ravi
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Univ Johns Hopkins
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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DK11751481.0T 2010-03-05 2011-03-04 Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner DK2542590T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31125510P 2010-03-05 2010-03-05
US201161435671P 2011-01-24 2011-01-24
PCT/US2011/027317 WO2011109789A2 (en) 2010-03-05 2011-03-04 Compositions and methods for targeted immunomodulatory antibodies and fusion proteins

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DK2542590T3 DK2542590T3 (da) 2017-08-28
DK2542590T4 true DK2542590T4 (da) 2020-07-13

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US (7) US8993524B2 (da)
EP (3) EP3260470A1 (da)
JP (4) JP6066732B2 (da)
CA (3) CA3083324A1 (da)
DK (1) DK2542590T4 (da)
ES (1) ES2638521T5 (da)
IL (5) IL323000A (da)
PL (1) PL2542590T5 (da)
PT (1) PT2542590T (da)
WO (1) WO2011109789A2 (da)

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EP2473531A4 (en) 2009-09-03 2013-05-01 Merck Sharp & Dohme Anti-gitr antibodies
WO2011066342A2 (en) * 2009-11-24 2011-06-03 Amplimmune, Inc. Simultaneous inhibition of pd-l1/pd-l2
CA3083324A1 (en) * 2010-03-05 2011-09-09 The Johns Hopkins University Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
DK3252076T3 (da) 2011-01-14 2019-12-02 Univ California Diagnostisk anvendelse af antistoffer mod ror-1-protein
JP6130307B2 (ja) 2011-03-17 2017-05-17 ザ ユニバーシティ オブ バーミンガム 再指向性免疫療法
US9822179B2 (en) * 2011-04-01 2017-11-21 Universitat Stuttgart Recombinant TNF ligand family member polypeptides with antibody binding domain and uses therefor
CA2777978A1 (en) * 2011-05-27 2012-11-27 Abbott Biotherapeutics Corp. Dac hyp compositions and methods
AU2012323856B2 (en) 2011-10-13 2017-05-25 EyePoint, Inc. Methods for treating Vascular Leak Syndrome and cancer
HUE059406T2 (hu) * 2011-10-17 2022-11-28 Io Biotech Aps PD-L1 alapú immunterápia
EP3575794A1 (en) 2012-02-10 2019-12-04 Seattle Genetics, Inc. Detection and treatment of cd30+ cancers
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