DK255786A - Quinazolinderivater eller farmaceutisk acceptable salte eller estere deraf, deres fremstilling og anvendelse som farmaceutika - Google Patents

Quinazolinderivater eller farmaceutisk acceptable salte eller estere deraf, deres fremstilling og anvendelse som farmaceutika Download PDF

Info

Publication number: DK255786A
Authority: DK; Denmark
Prior art keywords: group; heteroatom; quinazoline derivatives; pharmaceuticals; esters
Prior art date: 1985-05-31

Application number

DK255786A

Other languages

English (en)

Other versions

DK255786D0 (da

Inventor

Ann Lesley Jackman

David Richard Newell

Terence Richard Jones

Original Assignee

Nat Res Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-31

Filing date

1986-05-30

Publication date

1986-12-01

1986-05-30 Application filed by Nat Res Dev filed Critical Nat Res Dev

1986-05-30 Publication of DK255786D0 publication Critical patent/DK255786D0/da

1986-12-01 Publication of DK255786A publication Critical patent/DK255786A/da

Links

239000003814 drug Substances 0.000 title 1
JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical class N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
125000005842 heteroatom Chemical group 0.000 abstract 5
125000001183 hydrocarbyl group Chemical group 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 2
229920006395 saturated elastomer Polymers 0.000 abstract 2
229930195734 saturated hydrocarbon Natural products 0.000 abstract 2
229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000002837 carbocyclic group Chemical group 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK255786A 1985-05-31 1986-05-30 Quinazolinderivater eller farmaceutisk acceptable salte eller estere deraf, deres fremstilling og anvendelse som farmaceutika DK255786A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB858513754A GB8513754D0 (en)	1985-05-31	1985-05-31	Anti-cancer quinazoline derivatives

Publications (2)

Publication Number	Publication Date
DK255786D0 DK255786D0 (da)	1986-05-30
DK255786A true DK255786A (da)	1986-12-01

Family

ID=10579966

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK255786A DK255786A (da)	1985-05-31	1986-05-30	Quinazolinderivater eller farmaceutisk acceptable salte eller estere deraf, deres fremstilling og anvendelse som farmaceutika

Country Status (17)

Country	Link
US (1)	US5236927A (da)
EP (1)	EP0204529B1 (da)
JP (1)	JPS61282368A (da)
AT (1)	ATE87621T1 (da)
AU (1)	AU592271B2 (da)
DE (1)	DE3688150T2 (da)
DK (1)	DK255786A (da)
ES (1)	ES8800911A1 (da)
FI (1)	FI862303A7 (da)
GB (2)	GB8513754D0 (da)
GR (1)	GR861418B (da)
HU (1)	HUT45512A (da)
IL (1)	IL78910A0 (da)
NO (1)	NO862170L (da)
NZ (1)	NZ216363A (da)
PT (1)	PT82682B (da)
ZA (1)	ZA864051B (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8607683D0 (en) *	1986-03-27	1986-04-30	Ici Plc	Anti-tumor agents
GB8707053D0 (en) *	1987-03-25	1987-04-29	Ici Plc	Anti-tumour agents
US4857530A (en) *	1987-11-03	1989-08-15	Warner-Lambert Company	Substituted quinazolinones as anticancer agents
GB8809978D0 (en) *	1988-04-27	1988-06-02	Ici Plc	Anti-tumour agents
EP0365763A1 (en) *	1988-09-30	1990-05-02	Agouron Pharmaceuticals, Inc.	Antiproliferative cyclic compounds
US5286726A (en) *	1990-04-12	1994-02-15	The Regents Of The University Of Michigan	Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
GB9013615D0 (en)	1990-06-19	1990-08-08	Wellcome Found	Pharmaceutical compounds
US6762188B1 (en)	1990-06-19	2004-07-13	Smithkline Beecham Corporation	Pharmaceutically active benzoquinazoline compounds
GB9105771D0 (en) *	1991-03-19	1991-05-01	Cancer Res Inst Royal	Anti-cancer compounds
GB9205320D0 (en) *	1992-03-11	1992-04-22	Ici Plc	Anti-tumour compounds
GB9205907D0 (en) *	1992-03-18	1992-04-29	Cancer Res Inst Royal	Anti-cancer compounds
US5430148A (en) *	1992-03-31	1995-07-04	Agouron Pharmaceuticals, Inc.	Antiproliferative quinazolines
GB9223352D0 (en) *	1992-11-06	1992-12-23	Ici Plc	Tricyclic compounds
US7262058B2 (en) *	2001-03-09	2007-08-28	Nonda Katopodis	Method for determining lipid associated sialoprotein in body fluids
RU2005115106A (ru) *	2002-10-18	2005-10-10	Конинклейке Филипс Электроникс Н.В. (Nl)	Способ, система, устройство, сигнал и программный продукт для защиты метаданных в tv-anytime
CA2502302A1 (en) *	2002-11-04	2004-05-21	Nps Pharmaceuticals, Inc.	Quinazolinone compounds as calcilytics
EP1915351A1 (en) *	2005-07-15	2008-04-30	Schering Corporation	Quinazoline derivatives useful in cancer treatment
WO2007011623A1 (en) *	2005-07-15	2007-01-25	Schering Corporation	Quinazoline derivatives useful in cancer treatment
WO2008041118A2 (en)	2006-10-04	2008-04-10	Pfizer Products Inc.	Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists
TWI469971B (zh)	2007-10-26	2015-01-21	Univ California	二芳基乙內醯脲類化合物
LT2445502T (lt)	2009-06-25	2017-09-25	Alkermes Pharma Ireland Limited	Heterocikliniai junginiai, skirti neurologinių ir fiziologinių susirgimų gydymui
WO2011084846A1 (en) *	2010-01-07	2011-07-14	Alkermes, Inc.	Quaternary ammonium salt prodrugs
AU2011270701B2 (en)	2010-06-24	2015-05-14	Alkermes Pharma Ireland Limited	Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
BR112013023847B1 (pt)	2011-03-18	2021-02-23	Alkermes Pharma Ireland Limited	composições farmacêuticas compreendendo ésteres de sorbitano e uso das mesmas
AU2013235523B9 (en)	2012-03-19	2018-01-04	Alkermes Pharma Ireland Limited	Pharmaceutical compositions comprising glycerol esters
CA2867121C (en)	2012-03-19	2021-05-25	Alkermes Pharma Ireland Limited	Pharmaceutical compositions comprising fatty acid esters
AU2013235526B2 (en)	2012-03-19	2017-11-30	Alkermes Pharma Ireland Limited	Pharmaceutical compositions comprising benzyl alcohol
JP6654042B2 (ja)	2012-09-19	2020-02-26	アルカームスファーマアイルランドリミテッド	貯蔵安定性が改善された医薬組成物
CN106132415A (zh)	2014-03-20	2016-11-16	奥克梅斯制药爱尔兰有限公司	具有增加的注射速度的阿立哌唑制剂
EP3761983A1 (en)	2018-03-05	2021-01-13	Alkermes Pharma Ireland Limited	Aripiprazole dosing strategy
WO2024028999A1 (ja) *	2022-08-03	2024-02-08	Ils株式会社	Ｎ－［４－メチルアミノベンゾイル］－ｌ－グルタミン酸ジエチルエステルの製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1021196A (en) *	1964-02-20	1966-03-02	Parke Davis & Co	Novel amino acids and means for producing the same
US3471498A (en) *	1967-08-11	1969-10-07	Parke Davis & Co	Certain n-p-((2,4-diamino-6-quinazolinyl)-methyl)benzoylamino acids
DE3069468D1 (en) *	1979-12-19	1984-11-22	Nat Res Dev	Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
GB8607683D0 (en) *	1986-03-27	1986-04-30	Ici Plc	Anti-tumor agents

1985
- 1985-05-31 GB GB858513754A patent/GB8513754D0/en active Pending
1986
- 1986-05-26 IL IL78910A patent/IL78910A0/xx unknown
- 1986-05-30 NZ NZ216363A patent/NZ216363A/xx unknown
- 1986-05-30 GB GB08613184A patent/GB2175903B/en not_active Expired
- 1986-05-30 HU HU862288A patent/HUT45512A/hu unknown
- 1986-05-30 GR GR861418A patent/GR861418B/el unknown
- 1986-05-30 NO NO862170A patent/NO862170L/no unknown
- 1986-05-30 ZA ZA864051A patent/ZA864051B/xx unknown
- 1986-05-30 FI FI862303A patent/FI862303A7/fi not_active Application Discontinuation
- 1986-05-30 DE DE8686304148T patent/DE3688150T2/de not_active Expired - Fee Related
- 1986-05-30 ES ES555548A patent/ES8800911A1/es not_active Expired
- 1986-05-30 AU AU58220/86A patent/AU592271B2/en not_active Ceased
- 1986-05-30 PT PT82682A patent/PT82682B/pt not_active IP Right Cessation
- 1986-05-30 EP EP86304148A patent/EP0204529B1/en not_active Expired - Lifetime
- 1986-05-30 JP JP61125587A patent/JPS61282368A/ja active Pending
- 1986-05-30 DK DK255786A patent/DK255786A/da not_active Application Discontinuation
- 1986-05-30 AT AT86304148T patent/ATE87621T1/de not_active IP Right Cessation
1990
- 1990-12-12 US US07/625,695 patent/US5236927A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE3688150D1 (de)	1993-05-06
ES8800911A1 (es)	1987-12-01
EP0204529A3 (en)	1987-11-19
EP0204529B1 (en)	1993-03-31
ZA864051B (en)	1987-01-28
DE3688150T2 (de)	1993-07-29
GB8513754D0 (en)	1985-07-03
AU5822086A (en)	1986-12-04
HUT45512A (en)	1988-07-28
JPS61282368A (ja)	1986-12-12
DK255786D0 (da)	1986-05-30
ATE87621T1 (de)	1993-04-15
GR861418B (en)	1986-09-26
IL78910A0 (en)	1986-09-30
PT82682B (pt)	1988-03-03
EP0204529A2 (en)	1986-12-10
FI862303A0 (fi)	1986-05-30
GB2175903B (en)	1988-10-12
NO862170L (no)	1986-12-01
GB2175903A (en)	1986-12-10
US5236927A (en)	1993-08-17
NZ216363A (en)	1989-07-27
GB8613184D0 (en)	1986-07-02
FI862303A7 (fi)	1986-12-01
ES555548A0 (es)	1987-12-01
AU592271B2 (en)	1990-01-04
PT82682A (en)	1986-06-01

Legal Events

Date	Code	Title	Description
1993-01-25	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK255786A (da)	1986-12-01	Quinazolinderivater eller farmaceutisk acceptable salte eller estere deraf, deres fremstilling og anvendelse som farmaceutika
ES8300716A1 (es)	1982-11-01	Procedimiento para preparar derivados de 2-amino-4-hidroxi- quinazolina
ES8704938A1 (es)	1987-04-16	Procedimiento para preparar nuevos derivados aminicos heteroaromaticos
DK345989A (da)	1990-01-13	Quinolinderivater
DK114783A (da)	1983-09-11	Hidtil ukendte forbindelser, fremgangsmaader til deres fremstilling samt deres anvendelse som laegemidler
DK37189A (da)	1989-07-30	Substituerede quinoliner og cinnoliner, fremgangsmaader til deres fremstilling samt deres anvendelse
PT83647B (pt)	1989-05-31	Processo para a preparacao de novos derivados de benzimidazole com actividade farmacologica e de composicoes farmaceuticas que os contem
FR2526659B1 (fr)	1986-07-04	Medicaments immunomodulants a base de derives de l'acide phenylacetique
AR241422A1 (es)	1992-07-31	Procedimiento para la preparacion de derivados de difenil(metil-etil-0 etenil) piperidinas.
DK529585A (da)	1986-05-17	N-(6-methoxy-5-(perflouralkyl)-1-naphtholyl)-n-methylglyciner og deres thionaphthoyl analoge, deres fremstilling og anvendelse som laegemidler
PT89757A (pt)	1989-10-04	Processo para a preparacao de novos derivados da xantina e de composicoes farmaceuticas que os contem, uteis no tratamento da ulcera peptica
ES550971A0 (es)	1987-04-16	Un procedimiento para la preparacion de nuevos derivados de esteres fosforicos.
NO891381L (no)	1989-10-02	Fremgangsmaate for fremstilling av nye fluorfosfonatnukleotidderivater.
PT83975B (pt)	1989-05-12	Processo para a preparacao de derivados de 5-aminoalquil-beta-carbolinas e de composicoes farmaceuticas que os contem
ATE87307T1 (de)	1993-04-15	Isoindolinderivate und verfahren zu ihrer herstellung.
ES2003758A6 (es)	1988-11-16	Procedimiento para preparar nuevos derivados de acidos fenilaceticos
ATE144900T1 (de)	1996-11-15	Verwendung von xanthinderivaten gegen magengeschwüre
ES2001440A6 (es)	1988-05-16	Procedimiento de prepararion de nuevos derivados de catecol
ES2045335T3 (es)	1994-01-16	Un procedimiento para la preparacion de nuevas s-difluorometilhomocisteinas.
ES2039270T3 (es)	1993-09-16	Derivados de gamma-l-glutamil-4-nitroanilida y procedimiento para determinar actividad de gamma-gtp utilizandolos.