GR861418B - Anti-cancer quinazoline derivatives - Google Patents

Anti-cancer quinazoline derivatives

Info

Publication number
GR861418B
GR861418B GR861418A GR860101418A GR861418B GR 861418 B GR861418 B GR 861418B GR 861418 A GR861418 A GR 861418A GR 860101418 A GR860101418 A GR 860101418A GR 861418 B GR861418 B GR 861418B
Authority
GR
Greece
Prior art keywords
group
heteroatom
quinazoline derivatives
halogeno
chem
Prior art date
Application number
GR861418A
Other languages
English (en)
Inventor
Lesley Ann Jackman
Original Assignee
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Dev filed Critical Nat Res Dev
Publication of GR861418B publication Critical patent/GR861418B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR861418A 1985-05-31 1986-05-30 Anti-cancer quinazoline derivatives GR861418B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858513754A GB8513754D0 (en) 1985-05-31 1985-05-31 Anti-cancer quinazoline derivatives

Publications (1)

Publication Number Publication Date
GR861418B true GR861418B (en) 1986-09-26

Family

ID=10579966

Family Applications (1)

Application Number Title Priority Date Filing Date
GR861418A GR861418B (en) 1985-05-31 1986-05-30 Anti-cancer quinazoline derivatives

Country Status (17)

Country Link
US (1) US5236927A (el)
EP (1) EP0204529B1 (el)
JP (1) JPS61282368A (el)
AT (1) ATE87621T1 (el)
AU (1) AU592271B2 (el)
DE (1) DE3688150T2 (el)
DK (1) DK255786A (el)
ES (1) ES8800911A1 (el)
FI (1) FI862303A7 (el)
GB (2) GB8513754D0 (el)
GR (1) GR861418B (el)
HU (1) HUT45512A (el)
IL (1) IL78910A0 (el)
NO (1) NO862170L (el)
NZ (1) NZ216363A (el)
PT (1) PT82682B (el)
ZA (1) ZA864051B (el)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4857530A (en) * 1987-11-03 1989-08-15 Warner-Lambert Company Substituted quinazolinones as anticancer agents
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
EP0365763A1 (en) * 1988-09-30 1990-05-02 Agouron Pharmaceuticals, Inc. Antiproliferative cyclic compounds
US5286726A (en) * 1990-04-12 1994-02-15 The Regents Of The University Of Michigan Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
US6762188B1 (en) 1990-06-19 2004-07-13 Smithkline Beecham Corporation Pharmaceutically active benzoquinazoline compounds
GB9013615D0 (en) 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
GB9205320D0 (en) * 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
US7262058B2 (en) * 2001-03-09 2007-08-28 Nonda Katopodis Method for determining lipid associated sialoprotein in body fluids
RU2005115106A (ru) * 2002-10-18 2005-10-10 Конинклейке Филипс Электроникс Н.В. (Nl) Способ, система, устройство, сигнал и программный продукт для защиты метаданных в tv-anytime
US20060052345A1 (en) * 2002-11-04 2006-03-09 Nps Pharmaceuticals, Inc. Quinazolinone compounds as calcilytics
JP2009501235A (ja) * 2005-07-15 2009-01-15 シェーリング コーポレイション 癌処置において有用なキナゾリン誘導体
MX2008000744A (es) * 2005-07-15 2008-03-10 Schering Corp Derivados de quinazolina utiles en el tratamiento del cancer.
CA2663436A1 (en) 2006-10-04 2008-04-10 Pfizer Products Inc. Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists
EP2220050A2 (en) 2007-10-26 2010-08-25 The Regents Of The University Of California Diarylhydantoin compounds as androgen receptor modulators
ES3031438T3 (en) 2009-06-25 2025-07-08 Alkermes Pharma Ireland Ltd Heterocyclic compounds for the treatment of neurological and psychological disorders
AU2010339689B2 (en) * 2010-01-07 2015-02-19 Alkermes Pharma Ireland Limited Quaternary ammonium salt prodrugs
WO2011163594A2 (en) 2010-06-24 2011-12-29 Alkermes, Inc. Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
US9034867B2 (en) 2011-03-18 2015-05-19 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising sorbitan esters
JP6219918B2 (ja) 2012-03-19 2017-10-25 アルカームス ファーマ アイルランド リミテッド グリセロールエステルを含む医薬組成物
WO2013142198A1 (en) 2012-03-19 2013-09-26 Alkermes Pharma Ireland Limited Pharmaaceutical compositions comprising fatty acid esters
WO2013142205A1 (en) 2012-03-19 2013-09-26 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising benzyl alcohol
EP3718536A1 (en) 2012-09-19 2020-10-07 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
EP3119399A4 (en) 2014-03-20 2017-09-27 Alkermes Pharma Ireland Limited Aripiprazole formulations having increased injection speeds
CA3092335A1 (en) 2018-03-05 2019-09-12 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
WO2024028999A1 (ja) * 2022-08-03 2024-02-08 Ils株式会社 Ｎ－［４－メチルアミノベンゾイル］－ｌ－グルタミン酸ジエチルエステルの製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1021196A (en) * 1964-02-20 1966-03-02 Parke Davis & Co Novel amino acids and means for producing the same
US3471498A (en) * 1967-08-11 1969-10-07 Parke Davis & Co Certain n-p-((2,4-diamino-6-quinazolinyl)-methyl)benzoylamino acids
EP0031237B1 (en) * 1979-12-19 1984-10-17 National Research Development Corporation Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents

Also Published As

Publication number Publication date
DE3688150T2 (de) 1993-07-29
EP0204529A2 (en) 1986-12-10
GB2175903B (en) 1988-10-12
FI862303A7 (fi) 1986-12-01
JPS61282368A (ja) 1986-12-12
AU5822086A (en) 1986-12-04
NZ216363A (en) 1989-07-27
US5236927A (en) 1993-08-17
GB8613184D0 (en) 1986-07-02
GB8513754D0 (en) 1985-07-03
DK255786D0 (da) 1986-05-30
HUT45512A (en) 1988-07-28
FI862303A0 (fi) 1986-05-30
DE3688150D1 (de) 1993-05-06
GB2175903A (en) 1986-12-10
EP0204529B1 (en) 1993-03-31
ES8800911A1 (es) 1987-12-01
NO862170L (no) 1986-12-01
IL78910A0 (en) 1986-09-30
ATE87621T1 (de) 1993-04-15
ZA864051B (en) 1987-01-28
DK255786A (da) 1986-12-01
PT82682A (en) 1986-06-01
EP0204529A3 (en) 1987-11-19
PT82682B (pt) 1988-03-03
AU592271B2 (en) 1990-01-04
ES555548A0 (es) 1987-12-01

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