DK2598516T3 - Fremgangsmåde til proteinoprensning - Google Patents

Fremgangsmåde til proteinoprensning Download PDF

Info

Publication number: DK2598516T3
Authority: DK; Denmark
Prior art keywords: protein purification; purification; protein
Prior art date: 2010-07-27

Application number

DK11745810.9T

Other languages

English (en)

Inventor

Gavin Barry Wild

Original Assignee

Ucb Biopharma Sprl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-07-27

Filing date

2011-07-27

Publication date

2015-06-15

2011-07-27 Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl

2015-06-15 Application granted granted Critical

2015-06-15 Publication of DK2598516T3 publication Critical patent/DK2598516T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Analytical Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Enzymes And Modification Thereof (AREA)
Peptides Or Proteins (AREA)

DK11745810.9T 2010-07-27 2011-07-27 Fremgangsmåde til proteinoprensning DK2598516T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB1012599.5A GB201012599D0 (en)	2010-07-27	2010-07-27	Process for purifying proteins
PCT/GB2011/001129 WO2012013930A2 (en)	2010-07-27	2011-07-27	Process for purifying proteins

Publications (1)

Publication Number	Publication Date
DK2598516T3 true DK2598516T3 (da)	2015-06-15

Family

ID=42752868

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK11745810.9T DK2598516T3 (da)	2010-07-27	2011-07-27	Fremgangsmåde til proteinoprensning

Country Status (24)

Country	Link
US (1)	US9751930B2 (da)
EP (1)	EP2598516B8 (da)
JP (1)	JP5935222B2 (da)
KR (1)	KR101944121B1 (da)
CN (1)	CN103189385B (da)
AU (1)	AU2011284548B2 (da)
BR (1)	BR112013000177B1 (da)
CA (1)	CA2804099C (da)
CY (1)	CY1116526T1 (da)
DK (1)	DK2598516T3 (da)
ES (1)	ES2537877T3 (da)
GB (1)	GB201012599D0 (da)
HR (1)	HRP20150639T1 (da)
HU (1)	HUE026049T2 (da)
IL (1)	IL224044A (da)
ME (1)	ME02162B (da)
MX (1)	MX337184B (da)
PL (1)	PL2598516T3 (da)
PT (1)	PT2598516E (da)
RS (1)	RS54085B1 (da)
SG (2)	SG196862A1 (da)
SI (1)	SI2598516T1 (da)
SM (1)	SMT201500142B (da)
WO (1)	WO2012013930A2 (da)

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CA2774692C (en)	2009-09-24	2017-12-19	Ucb Pharma S.A.	Bacterial strain for recombinant protein expression, having protease deficient degp retaining chaperone activity, and knocked out tsp and ptr genes
GB201000590D0 (en)	2010-01-14	2010-03-03	Ucb Pharma Sa	Bacterial host strain
GB201000591D0 (en)	2010-01-14	2010-03-03	Ucb Pharma Sa	Bacterial hoist strain
GB201000587D0 (en)	2010-01-14	2010-03-03	Ucb Pharma Sa	Bacterial hoist strain
GB201001791D0 (en)	2010-02-03	2010-03-24	Ucb Pharma Sa	Process for obtaining antibodies
SMT201800068T1 (it)	2011-07-13	2018-03-08	Ucb Biopharma Sprl	Ceppo ospite batterico che esprime dsbc ricombinante
GB201208367D0 (en) *	2012-05-14	2012-06-27	Ucb Pharma Sa	Biological product
WO2013180648A1 (en)	2012-05-31	2013-12-05	Agency For Science, Technology And Research	Methods for use of mixed multifunctional surfaces for reducing aggregate content in protein preparations
SG11201407809QA (en)	2012-05-31	2014-12-30	Agency Science Tech & Res	Chromatographic purification of immunoglobulin g preparations with particles having multimodal functionalities
CN108064308B (zh) *	2014-11-05	2023-06-09	豪夫迈·罗氏有限公司	细菌中产生双链蛋白的方法
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ES3046837T3 (en)	2014-12-22	2025-12-02	UCB Biopharma SRL	Method of protein manufacture
HRP20192217T1 (hr) *	2015-03-06	2020-02-21	F. Hoffmann - La Roche Ag	ULTRA-PROČIŠĆENI DsbA I DsbC TE POSTUPCI NJIHOVE IZRADE I UPORABE
EP3824906A1 (en)	2016-12-21	2021-05-26	Amgen Inc.	Anti-tnf alpha antibody formulations
CN110272491B (zh) *	2018-03-13	2023-01-24	江苏恒瑞医药股份有限公司	一种抗pd-1抗体的纯化工艺
ES3026707T3 (en) *	2019-08-05	2025-06-12	Wacker Chemie Ag	Bacterial strain for releasing a recombinant protein in a fermentation method

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US7662587B1 (en)	2009-03-05	2010-02-16	E. I. Du Pont De Nemours And Company	Gene knockout mutations that increase peptide production
CA2774692C (en)	2009-09-24	2017-12-19	Ucb Pharma S.A.	Bacterial strain for recombinant protein expression, having protease deficient degp retaining chaperone activity, and knocked out tsp and ptr genes
US8470552B2 (en)	2009-10-12	2013-06-25	Keck Graduate Institute	Strategy to reduce lactic acid production and control PH in animal cell culture
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GB201000590D0 (en)	2010-01-14	2010-03-03	Ucb Pharma Sa	Bacterial host strain
GB201000588D0 (en)	2010-01-14	2010-03-03	Ucb Pharma Sa	Bacterial host strain
GB201000591D0 (en) *	2010-01-14	2010-03-03	Ucb Pharma Sa	Bacterial hoist strain
GB201000587D0 (en)	2010-01-14	2010-03-03	Ucb Pharma Sa	Bacterial hoist strain
GB201001791D0 (en)	2010-02-03	2010-03-24	Ucb Pharma Sa	Process for obtaining antibodies
SMT201800068T1 (it)	2011-07-13	2018-03-08	Ucb Biopharma Sprl	Ceppo ospite batterico che esprime dsbc ricombinante
EP2546267A1 (en)	2011-07-13	2013-01-16	UCB Pharma S.A.	Bacterial host strain expressing recombinant DsbC
GB201208367D0 (en)	2012-05-14	2012-06-27	Ucb Pharma Sa	Biological product

2010
- 2010-07-27 GB GBGB1012599.5A patent/GB201012599D0/en not_active Ceased
2011
- 2011-07-27 KR KR1020137004911A patent/KR101944121B1/ko active Active
- 2011-07-27 DK DK11745810.9T patent/DK2598516T3/da active
- 2011-07-27 CA CA2804099A patent/CA2804099C/en active Active
- 2011-07-27 SG SG2014005441A patent/SG196862A1/en unknown
- 2011-07-27 SI SI201130516T patent/SI2598516T1/sl unknown
- 2011-07-27 RS RS20150429A patent/RS54085B1/sr unknown
- 2011-07-27 US US13/812,350 patent/US9751930B2/en active Active
- 2011-07-27 PL PL11745810T patent/PL2598516T3/pl unknown
- 2011-07-27 CN CN201180036417.8A patent/CN103189385B/zh active Active
- 2011-07-27 HU HUE11745810A patent/HUE026049T2/en unknown
- 2011-07-27 SG SG2013001318A patent/SG186974A1/en unknown
- 2011-07-27 WO PCT/GB2011/001129 patent/WO2012013930A2/en not_active Ceased
- 2011-07-27 PT PT117458109T patent/PT2598516E/pt unknown
- 2011-07-27 JP JP2013521208A patent/JP5935222B2/ja active Active
- 2011-07-27 ES ES11745810.9T patent/ES2537877T3/es active Active
- 2011-07-27 ME MEP-2015-94A patent/ME02162B/me unknown
- 2011-07-27 AU AU2011284548A patent/AU2011284548B2/en active Active
- 2011-07-27 EP EP11745810.9A patent/EP2598516B8/en active Active
- 2011-07-27 MX MX2013000899A patent/MX337184B/es active IP Right Grant
- 2011-07-27 HR HRP20150639TT patent/HRP20150639T1/hr unknown
- 2011-07-27 BR BR112013000177-1A patent/BR112013000177B1/pt not_active IP Right Cessation
2012
- 2012-12-31 IL IL224044A patent/IL224044A/en active IP Right Grant
2015
- 2015-06-18 SM SM201500142T patent/SMT201500142B/xx unknown
- 2015-06-23 CY CY20151100535T patent/CY1116526T1/el unknown

Also Published As

Publication number	Publication date
KR101944121B1 (ko)	2019-01-30
PL2598516T3 (pl)	2015-10-30
RS54085B1 (sr)	2015-10-30
EP2598516B1 (en)	2015-03-25
ES2537877T3 (es)	2015-06-15
HUE026049T2 (en)	2016-05-30
KR20130103713A (ko)	2013-09-24
PT2598516E (pt)	2015-07-22
HRP20150639T1 (hr)	2015-07-17
EP2598516B8 (en)	2015-07-15
IL224044A (en)	2016-09-29
SG186974A1 (en)	2013-02-28
GB201012599D0 (en)	2010-09-08
JP2013535463A (ja)	2013-09-12
AU2011284548B2 (en)	2015-11-26
US20130178607A1 (en)	2013-07-11
BR112013000177A2 (pt)	2020-09-24
US9751930B2 (en)	2017-09-05
WO2012013930A3 (en)	2012-05-03
JP5935222B2 (ja)	2016-06-15
SI2598516T1 (sl)	2015-07-31
CA2804099A1 (en)	2012-02-02
ME02162B (me)	2015-10-20
SMT201500142B (it)	2015-09-07
CN103189385A (zh)	2013-07-03
EP2598516A2 (en)	2013-06-05
WO2012013930A2 (en)	2012-02-02
MX2013000899A (es)	2013-05-22
BR112013000177B1 (pt)	2021-11-09
CY1116526T1 (el)	2017-03-15
SG196862A1 (en)	2014-02-13
CN103189385B (zh)	2016-06-15
AU2011284548A1 (en)	2013-02-07
CA2804099C (en)	2018-07-10
MX337184B (es)	2016-02-16

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