DK264683A - Nona- og decapeptidanaloge af luteiniseringshormonfrigoerende hormon - Google Patents

Nona- og decapeptidanaloge af luteiniseringshormonfrigoerende hormon Download PDF

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Publication number
DK264683A
DK264683A DK264683A DK264683A DK264683A DK 264683 A DK264683 A DK 264683A DK 264683 A DK264683 A DK 264683A DK 264683 A DK264683 A DK 264683A DK 264683 A DK264683 A DK 264683A
Authority
DK
Denmark
Prior art keywords
hormon
lute
decapeptide
nona
initializing
Prior art date
Application number
DK264683A
Other languages
English (en)
Other versions
DK264683D0 (da
DK171483B1 (da
Inventor
John J Nestor
Brian H Vickery
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/451,671 external-priority patent/US4481190A/en
Priority claimed from US06/472,692 external-priority patent/US4581169A/en
Priority claimed from US06/495,226 external-priority patent/US4667014A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK264683D0 publication Critical patent/DK264683D0/da
Publication of DK264683A publication Critical patent/DK264683A/da
Application granted granted Critical
Publication of DK171483B1 publication Critical patent/DK171483B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK264683A 1982-06-10 1983-06-09 Aminosyrederivater DK171483B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US38710182A 1982-06-10 1982-06-10
US38710182 1982-06-10
US45167182 1982-12-21
US06/451,671 US4481190A (en) 1982-12-21 1982-12-21 Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
US47269283 1983-03-07
US06/472,692 US4581169A (en) 1982-12-21 1983-03-07 Nona-peptide and deca-peptide analogs of LHRH, useful as LHRH antagonists
US06/495,226 US4667014A (en) 1983-03-07 1983-05-20 Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
US49522683 1983-05-20

Publications (3)

Publication Number Publication Date
DK264683D0 DK264683D0 (da) 1983-06-09
DK264683A true DK264683A (da) 1983-12-11
DK171483B1 DK171483B1 (da) 1996-11-25

Family

ID=27503273

Family Applications (1)

Application Number Title Priority Date Filing Date
DK264683A DK171483B1 (da) 1982-06-10 1983-06-09 Aminosyrederivater

Country Status (12)

Country Link
EP (1) EP0097031B1 (da)
JP (1) JPH0610184B2 (da)
KR (1) KR910002550B1 (da)
AU (2) AU569036B2 (da)
CA (1) CA1264760C (da)
DE (1) DE3378053D1 (da)
DK (1) DK171483B1 (da)
ES (2) ES523128A0 (da)
FI (1) FI832053L (da)
IE (1) IE55164B1 (da)
IL (2) IL78380A (da)
NO (2) NO832098L (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL70888A0 (en) * 1983-03-10 1984-05-31 Salk Inst For Biological Studi Gn rh antagonist peptides and pharmaceutical compositions containing them
ZA846154B (en) * 1983-08-16 1985-03-27 Akzo Nv Lh-rh antagonists
EP0145032B1 (en) * 1983-08-16 1987-11-04 Akzo N.V. Lh- rh antagonists
US4530920A (en) * 1983-11-07 1985-07-23 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists
US4647653A (en) * 1984-08-23 1987-03-03 Tulane Educational Fund Therapeutic peptides
US4690916A (en) * 1984-11-13 1987-09-01 Syntex (U.S.A.) Inc. Nona and decapeptide analogs of LHRH useful as LHRH antagonists
US4677193A (en) * 1985-02-22 1987-06-30 The Salk Institute For Biological Studies Peptides containing an aliphatic-aromatic ketone side chain
US4866160A (en) * 1985-04-09 1989-09-12 The Administrators Of The Tulane Educational Fund Therapeutic decapeptides
ZA862570B (en) * 1985-04-09 1986-12-30 Univ Tulane Therapeutic decapeptides
HU194280B (en) * 1985-10-22 1988-01-28 Richter Gedeon Vegyeszet Process for producing new gonadoliberin analogues of high effectivity and pharmaceutical compositions containing them
US4761398A (en) * 1986-08-18 1988-08-02 Embrex, Inc. Method of inducing birds to molt
EP0268066A3 (en) * 1986-10-17 1990-07-11 Syntex (U.S.A.) Inc. Fertility control and uterine therapy in dogs with luteinizing hormone releasing hormone antagonists
US4801577A (en) * 1987-02-05 1989-01-31 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
US4800191A (en) * 1987-07-17 1989-01-24 Schally Andrew Victor LHRH antagonists
US4935491A (en) * 1987-08-24 1990-06-19 Board Of Regents, The University Of Texas System Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
US5171835A (en) * 1988-10-21 1992-12-15 The Administrators Of The Tulane Educational Fund LHRH antagonists
DE3842010A1 (de) * 1988-12-14 1990-06-21 Hoechst Ag Kompetitive gonadoliberin-antagonisten
US5084443A (en) * 1989-12-04 1992-01-28 Biomeasure, Inc. Promoting expression of acetylcholine receptors with lhrh antagonist
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
JPH0628601U (ja) * 1992-09-02 1994-04-15 京都度器株式会社 巻 尺
US5656727A (en) * 1992-09-15 1997-08-12 The Administrators Of The Tulane Educational Fund Antagonists of LHRH
US5480969A (en) * 1992-09-15 1996-01-02 The Administrators Of The Tulane Educational Fund Antagonists of LHRH
US6369272B1 (en) 1997-01-13 2002-04-09 Glaxosmithkline Nitric oxide synthase inhibitors
US6620848B2 (en) 1997-01-13 2003-09-16 Smithkline Beecham Corporation Nitric oxide synthase inhibitors
GB9811599D0 (en) 1998-05-30 1998-07-29 Glaxo Group Ltd Nitric oxide synthase inhibitors
ATE441115T1 (de) * 2001-11-05 2009-09-15 Irm Llc Markierungsreagens und anwendungsverfahren
AU2005303610B2 (en) * 2004-11-12 2011-07-21 Ucl Business Plc Guanidine derivatives as inhibitors of DDAH
FR3020810B1 (fr) * 2014-05-06 2016-05-06 Servier Lab Nouveau sel de l'ivabradine et son procede de preparation.
JP2025001049A (ja) * 2021-09-01 2025-01-08 積水メディカル株式会社 アルギニン誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3835108A (en) * 1972-02-15 1974-09-10 American Home Prod Process for preparing the releasing hormone of luteinizing hormone(lh)and of follicle stimulating hormone(fsh),salts and compositions thereof,and intermediates therefor
US3929759A (en) * 1974-11-04 1975-12-30 American Home Prod P-Glu-D-Phe-Trp-Ser-Tyr-D-Arg-Leu-Arg-Pro-Gly-NH{HD 2 {B and intermediates
NZ181036A (en) * 1975-06-12 1978-12-18 A Schally Luteinising hormone releasing hormone analogues and intermediates therefor
ZA829041B (en) * 1981-12-10 1983-09-28 David Howard Coy Lh-rh antagonists

Also Published As

Publication number Publication date
FI832053A7 (fi) 1983-12-11
AU7941887A (en) 1988-01-21
IL78380A (en) 1986-08-31
ES8504110A1 (es) 1985-04-16
IL68938A (en) 1986-08-31
FI832053A0 (fi) 1983-06-08
CA1264760C (en) 1990-01-23
KR840005081A (ko) 1984-11-03
IE831359L (en) 1983-12-10
AU613878B2 (en) 1991-08-15
DK264683D0 (da) 1983-06-09
EP0097031A2 (en) 1983-12-28
AU1567483A (en) 1983-12-15
EP0097031B1 (en) 1988-09-21
EP0097031A3 (en) 1984-11-07
IL68938A0 (en) 1983-10-31
ES537653A0 (es) 1985-12-16
DK171483B1 (da) 1996-11-25
NO832098L (no) 1983-12-12
IE55164B1 (en) 1990-06-20
AU569036B2 (en) 1988-01-21
JPS5962556A (ja) 1984-04-10
NO834404L (no) 1983-12-12
FI832053L (fi) 1983-12-11
KR910002550B1 (ko) 1991-04-24
JPH0610184B2 (ja) 1994-02-09
ES8603194A1 (es) 1985-12-16
ES523128A0 (es) 1985-04-16
DE3378053D1 (en) 1988-10-27

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