DK2658965T3 - Fremgangsmåde til fremstilling af inducerede pluripotente stamceller og differentierede celler - Google Patents

Fremgangsmåde til fremstilling af inducerede pluripotente stamceller og differentierede celler Download PDF

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Publication number
DK2658965T3
DK2658965T3 DK11805858.5T DK11805858T DK2658965T3 DK 2658965 T3 DK2658965 T3 DK 2658965T3 DK 11805858 T DK11805858 T DK 11805858T DK 2658965 T3 DK2658965 T3 DK 2658965T3
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Denmark
Prior art keywords
preparation
pluripotent stem
cells
induced pluripotent
stem cells
Prior art date
Application number
DK11805858.5T
Other languages
English (en)
Inventor
Johannes Grillari
Regina Grillari
Duanqing Pei
Ting Zhou
Miguel Esteban
Original Assignee
Universität Für Bodenkultur Wien
Guangzhou Inst Of Biomedicine And Health
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Filing date
Publication date
Priority claimed from EP11152519A external-priority patent/EP2481795A1/en
Application filed by Universität Für Bodenkultur Wien, Guangzhou Inst Of Biomedicine And Health filed Critical Universität Für Bodenkultur Wien
Application granted granted Critical
Publication of DK2658965T3 publication Critical patent/DK2658965T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK11805858.5T 2010-12-31 2011-12-23 Fremgangsmåde til fremstilling af inducerede pluripotente stamceller og differentierede celler DK2658965T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2010/002226 2010-12-31
EP11152519A EP2481795A1 (en) 2011-01-28 2011-01-28 Method of generating induced pluripotent stem cells and differentiated cells
PCT/EP2011/073962 WO2012089669A1 (en) 2010-12-31 2011-12-23 Method of generating induced pluripotent stem cells and differentiated cells

Publications (1)

Publication Number Publication Date
DK2658965T3 true DK2658965T3 (da) 2016-06-13

Family

ID=45464553

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11805858.5T DK2658965T3 (da) 2010-12-31 2011-12-23 Fremgangsmåde til fremstilling af inducerede pluripotente stamceller og differentierede celler

Country Status (10)

Country Link
US (1) US9926532B2 (da)
EP (1) EP2658965B1 (da)
JP (2) JP2014501114A (da)
BR (1) BR112013016592B1 (da)
CA (1) CA2823265C (da)
DK (1) DK2658965T3 (da)
EA (1) EA028902B1 (da)
ES (1) ES2575605T3 (da)
PT (1) PT2658965E (da)
WO (1) WO2012089669A1 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
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US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
US9782443B2 (en) * 2013-02-05 2017-10-10 Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences Preparing tooth-like structure using stem cell
WO2015140257A1 (en) * 2014-03-19 2015-09-24 INSERM (Institut National de la Santé et de la Recherche Médicale) A method for inducing human cholangiocyte differentiation
CN106661548B (zh) 2014-05-28 2020-12-11 儿童医院医疗中心 用于经由定向分化将前体细胞转化为胃组织的方法和系统
JP6804438B2 (ja) 2014-10-17 2020-12-23 チルドレンズ ホスピタル メディカル センター 多能性幹細胞を使用するヒト小腸のｉｎ ｖｉｖｏモデル、並びにそれを作製、及び使用する方法
AU2015372420B2 (en) * 2014-12-22 2021-02-25 University Of South Australia Method of inducing beta cells from urine-derived cells using small molecules
AU2016211671B2 (en) 2015-01-26 2022-05-26 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
CA2995582A1 (en) 2015-08-19 2017-02-23 Children's Research Institute, Children's National Medical Center Compositions and methods for treating graft versus host disease
CA3003152A1 (en) 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
ES2929758T3 (es) 2016-05-05 2022-12-01 Childrens Hospital Med Ct Métodos para la fabricación in vitro de tejido del fondo gástrico y composiciones relacionadas con el mismo
KR102729404B1 (ko) 2016-11-04 2024-11-14 칠드런즈 호스피탈 메디칼 센터 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법
JP7068305B2 (ja) 2016-12-05 2022-05-16 チルドレンズ ホスピタル メディカル センター 結腸オルガノイドならびにその作製方法および使用方法
US12281334B2 (en) 2017-04-14 2025-04-22 Children's Hospital Medical Center Multi donor stem cell compositions and methods of making same
EP3694603B1 (en) 2017-10-10 2026-04-08 Children's Hospital Medical Center Esophageal tissue and/or organoid compositions and methods of making same
US12379372B2 (en) 2017-12-21 2025-08-05 Children's Hospital Medical Center Digitalized human organoids and methods of using same
KR102887406B1 (ko) 2018-07-26 2025-11-19 칠드런즈 호스피탈 메디칼 센터 간-담도-췌장 조직 및 이를 제조하는 방법
AU2019339410A1 (en) 2018-09-12 2021-04-15 Children's Hospital Medical Center Organoid compositions for the production of hematopoietic stem cells and derivatives thereof
WO2020160371A1 (en) 2019-02-01 2020-08-06 The University Of Hong Kong Innervated organoid compositions and methods of making same
KR102150489B1 (ko) * 2019-04-09 2020-09-01 고려대학교 산학협력단 소변세포로부터 신장전구세포로의 직접 역분화를 유도하는 방법 및 이의 방법으로 역분화된 신장전구세포를 포함하는 신장세포 손상 질환 예방 또는 치료용 약학 조성물
WO2020243613A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
WO2020243633A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
CN112143706A (zh) * 2020-09-27 2020-12-29 中国科学院广州生物医药与健康研究院 一种将尿液细胞重编程为诱导性多能干细胞的方法
JP2022104813A (ja) * 2020-12-29 2022-07-11 アイ ピース，インコーポレイテッド リプログラミング因子を導入された細胞の培養方法
CN113122505A (zh) * 2021-04-13 2021-07-16 四川大学华西医院 一种通过逆病毒获取尿源诱导多能干细胞的方法
EP4553155A4 (en) 2023-01-23 2025-12-17 Pola Chem Ind Inc METHOD FOR PRODUCING INDUCED MULTIPOTENC STEM CELLS USING EPITHELIAL CELLS

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW438973B (en) 1995-12-19 2001-06-07 Sysmex Corp Apparatus and method for analyzing solid components in urine
JP3589113B2 (ja) * 1998-09-24 2004-11-17 田辺製薬株式会社 腎疾患治療薬およびそのスクリーニング方法
EP2146728A4 (en) * 2007-05-21 2010-12-29 Univ Wake Forest Health Sciences PROGENITOR CELLS FROM URINE AND METHODS FOR THEIR USE
US20100111914A1 (en) * 2007-05-21 2010-05-06 Yuanyuan Zhang Stem cells from urine and methods for using the same
AU2008297011B2 (en) 2007-08-31 2014-06-12 Whitehead Institute For Biomedical Research Wnt pathway stimulation in reprogramming somatic cells
JP2011525794A (ja) 2008-06-26 2011-09-29 国立大学法人大阪大学 ｉＰＳ細胞の製造方法および製造キット
CA2695590C (en) * 2008-06-27 2018-01-09 Kyoto University Method of efficiently establishing induced pluripotent stem cells
US20120189595A1 (en) * 2008-09-25 2012-07-26 Salk Institute For Biological Studies Induced pluripotent stem cells and methods of use
US9249412B2 (en) * 2009-01-26 2016-02-02 Fred Zacouto Simplified method for partial genetic and epigenetic reprogramming of cells using siRNA specific for a heterochromatin protein 1
JP2010207162A (ja) * 2009-03-11 2010-09-24 Japan Health Science Foundation Ｂａｃクローンを用いる尿路上皮癌の発生リスク評価方法及び予後予測方法

Also Published As

Publication number Publication date
BR112013016592B1 (pt) 2022-03-15
EA201300780A1 (ru) 2013-11-29
ES2575605T3 (es) 2016-06-29
CA2823265A1 (en) 2012-07-05
US9926532B2 (en) 2018-03-27
JP2014501114A (ja) 2014-01-20
EA028902B1 (ru) 2018-01-31
US20130323782A1 (en) 2013-12-05
EP2658965A1 (en) 2013-11-06
JP2017169574A (ja) 2017-09-28
WO2012089669A1 (en) 2012-07-05
PT2658965E (pt) 2016-06-06
BR112013016592A2 (pt) 2021-03-30
CA2823265C (en) 2019-05-21
EP2658965B1 (en) 2016-03-02

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