DK2694662T3 - Fremgangsmåder til forbedring af produktudbytte og fremstilling i en mikroorganisme gennem addition af alternerende elektronacceptorer - Google Patents
Fremgangsmåder til forbedring af produktudbytte og fremstilling i en mikroorganisme gennem addition af alternerende elektronacceptorer Download PDFInfo
- Publication number
- DK2694662T3 DK2694662T3 DK12713845.1T DK12713845T DK2694662T3 DK 2694662 T3 DK2694662 T3 DK 2694662T3 DK 12713845 T DK12713845 T DK 12713845T DK 2694662 T3 DK2694662 T3 DK 2694662T3
- Authority
- DK
- Denmark
- Prior art keywords
- microorganism
- production
- methods
- addition
- product yield
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- 239000000370 acceptor Substances 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
- C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/0101—Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01054—Formate C-acetyltransferase (2.3.1.54), i.e. pyruvate formate-lyase or PFL
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161472085P | 2011-04-05 | 2011-04-05 | |
| PCT/US2012/032443 WO2012138942A1 (en) | 2011-04-05 | 2012-04-05 | Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2694662T3 true DK2694662T3 (da) | 2020-03-02 |
Family
ID=45952666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12713845.1T DK2694662T3 (da) | 2011-04-05 | 2012-04-05 | Fremgangsmåder til forbedring af produktudbytte og fremstilling i en mikroorganisme gennem addition af alternerende elektronacceptorer |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US8956851B2 (da) |
| EP (2) | EP3483279A1 (da) |
| CN (2) | CN103649321B (da) |
| BR (2) | BR112013025753A8 (da) |
| CA (2) | CA2832279C (da) |
| DK (1) | DK2694662T3 (da) |
| WO (1) | WO2012138942A1 (da) |
| ZA (1) | ZA201307441B (da) |
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| CA2832279C (en) | 2011-04-05 | 2024-03-05 | Mascoma Corporation | Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors |
| EP2890784A1 (en) | 2012-08-29 | 2015-07-08 | Lallemand Hungary Liquidity Management LLC | Expression of enzymes in yeast for lignocellulose derived oligomer cbp |
| EP3498829A1 (en) | 2012-11-09 | 2019-06-19 | Lallemand Hungary Liquidity Management LLC | Method for acetate consumption during ethanolic fermentation of cellulosic feedstocks |
| BR112015011544B1 (pt) | 2012-11-20 | 2022-08-16 | Lallemand Hungary Liquidity Management Llc | Microrganismo recombinante, composição compreendendo o mesmo, método de produção de etanol e co-cultura |
| AU2014244216A1 (en) | 2013-03-14 | 2015-09-24 | E.I. Du Pont De Nemours And Company | Glycerol 3- phosphate dehydrogenase for butanol production |
| CA2905133C (en) | 2013-03-15 | 2024-03-05 | Lallemand Hungary Liquidity Management Llc | Methods for regulating nitrogen metabolism during the production of ethanol from corn by metabolically engineered yeast strains |
| MX377110B (es) * | 2013-08-15 | 2025-03-07 | Danstar Ferment Ag | Metodos para la mejora del rendimiento y produccion de producto en un microorganismo a traves del reciclaje de glicerol. |
| WO2015041940A2 (en) * | 2013-09-19 | 2015-03-26 | Shell Oil Company | Novel yeast strains |
| WO2015087327A1 (en) | 2013-12-10 | 2015-06-18 | Yeda Research And Development Co. Ltd. | Use of enzymes which catalyze pyruvate synthesis from formate and acetyl-coa and bacteria expressing same |
| KR102219700B1 (ko) * | 2014-06-23 | 2021-02-24 | 삼성전자주식회사 | Fps1의 활성이 감소된, 내산성을 갖는 효모 세포 및 그를 이용하여 락테이트를 생산하는 방법 |
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| MX2018002705A (es) | 2015-09-04 | 2018-12-19 | Lallemand Hungary Liquidity Man Llc | Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas. |
| EP3371317A1 (en) | 2015-11-06 | 2018-09-12 | Lallemand Hungary Liquidity Management LLC | Limiting yeast-produced trehalose in fermentation |
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| MX2019000209A (es) | 2016-07-01 | 2019-11-12 | Lallemand Hungary Liquidity Man Llc | Alfa-amilasas para combinacion con glucoamilasas para mejorar la sacarificacion. |
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| CN110177879A (zh) | 2016-12-22 | 2019-08-27 | 拉勒曼德匈牙利流动性管理有限责任公司 | 重组酵母宿主细胞的亚硫酸盐耐受性 |
| WO2018136385A1 (en) | 2017-01-18 | 2018-07-26 | Danisco Us Inc. | Modified yeast cells that overexpress a dna polymerase subunit |
| BR112019016021A2 (pt) * | 2017-02-02 | 2020-05-26 | Lallemand Hungary Liquidity Management Llc | Expressão de protease heteróloga para aperfeiçoar a fermentação alcoólica |
| BR112019019701A2 (pt) | 2017-03-24 | 2020-07-14 | Danisco Us Inc. | redução de acetato e glicerol em levedura modificada que tem um caminho de produção de etanol exógeno |
| US20210147885A1 (en) | 2017-04-17 | 2021-05-20 | Danisco Us Inc | Selected acetyl-coa synthase enzymes for reduction of acetate production in yeast |
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| CN110741014B (zh) | 2017-06-06 | 2024-04-09 | 丹尼斯科美国公司 | 具有改善的醇生产的酵母 |
| UY37835A (es) | 2017-08-08 | 2019-03-29 | Danisco Us Inc | Producción incrementada de etanol por levaduras que albergan alelos del activador de transcripción constitutivo mal |
| EP3676288A1 (en) | 2017-08-29 | 2020-07-08 | Danisco US Inc. | Modified yeast comprising glucose-specific, atp-mediated transporters |
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| CN112105726A (zh) | 2018-03-06 | 2020-12-18 | 丹尼斯科美国公司 | 使用gcy1和dak1来增加酵母的乙醇生产的组合物和方法 |
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-
2012
- 2012-04-05 CA CA2832279A patent/CA2832279C/en active Active
- 2012-04-05 US US14/110,075 patent/US8956851B2/en active Active
- 2012-04-05 EP EP18197527.7A patent/EP3483279A1/en not_active Withdrawn
- 2012-04-05 WO PCT/US2012/032443 patent/WO2012138942A1/en not_active Ceased
- 2012-04-05 BR BR112013025753A patent/BR112013025753A8/pt not_active Application Discontinuation
- 2012-04-05 CN CN201280025218.1A patent/CN103649321B/zh active Active
- 2012-04-05 BR BR122019017739-2A patent/BR122019017739B1/pt active IP Right Grant
- 2012-04-05 EP EP12713845.1A patent/EP2694662B1/en active Active
- 2012-04-05 CN CN201910530568.7A patent/CN110423705A/zh active Pending
- 2012-04-05 CA CA3227563A patent/CA3227563A1/en active Pending
- 2012-04-05 DK DK12713845.1T patent/DK2694662T3/da active
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2013
- 2013-10-04 ZA ZA2013/07441A patent/ZA201307441B/en unknown
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2015
- 2015-02-17 US US14/624,163 patent/US9719098B2/en active Active
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2017
- 2017-06-30 US US15/639,152 patent/US11034967B2/en active Active
-
2021
- 2021-05-10 US US17/316,051 patent/US20220098600A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN103649321B (zh) | 2019-07-16 |
| EP3483279A1 (en) | 2019-05-15 |
| US20150232863A1 (en) | 2015-08-20 |
| EP2694662A1 (en) | 2014-02-12 |
| ZA201307441B (en) | 2016-05-25 |
| BR112013025753A8 (pt) | 2018-06-12 |
| BR122019017739B1 (pt) | 2021-06-22 |
| US9719098B2 (en) | 2017-08-01 |
| CN110423705A (zh) | 2019-11-08 |
| US20170356000A1 (en) | 2017-12-14 |
| WO2012138942A1 (en) | 2012-10-11 |
| CA3227563A1 (en) | 2012-10-11 |
| CN103649321A (zh) | 2014-03-19 |
| BR112013025753A2 (pt) | 2018-04-10 |
| US11034967B2 (en) | 2021-06-15 |
| US20140186930A1 (en) | 2014-07-03 |
| EP2694662B1 (en) | 2020-01-08 |
| US20220098600A1 (en) | 2022-03-31 |
| CA2832279A1 (en) | 2012-10-11 |
| US8956851B2 (en) | 2015-02-17 |
| CA2832279C (en) | 2024-03-05 |
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