DK272182A - Fremgangsmaade til fremstilling af oralt effektive aporphin-forbindelser eller dopamin-agonist-forbindelser med ikke aporphinstruktur eller farmaceutisk acceptable syreadditionssalte deraf - Google Patents

Fremgangsmaade til fremstilling af oralt effektive aporphin-forbindelser eller dopamin-agonist-forbindelser med ikke aporphinstruktur eller farmaceutisk acceptable syreadditionssalte deraf Download PDF

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Publication number
DK272182A
DK272182A DK272182A DK272182A DK272182A DK 272182 A DK272182 A DK 272182A DK 272182 A DK272182 A DK 272182A DK 272182 A DK272182 A DK 272182A DK 272182 A DK272182 A DK 272182A
Authority
DK
Denmark
Prior art keywords
aporphin
compounds
procedure
preparation
acid addition
Prior art date
Application number
DK272182A
Other languages
Danish (da)
English (en)
Inventor
J L Neumeyer
Original Assignee
Univ Northeastern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/379,557 external-priority patent/US4543256A/en
Application filed by Univ Northeastern filed Critical Univ Northeastern
Publication of DK272182A publication Critical patent/DK272182A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK272182A 1981-06-18 1982-06-17 Fremgangsmaade til fremstilling af oralt effektive aporphin-forbindelser eller dopamin-agonist-forbindelser med ikke aporphinstruktur eller farmaceutisk acceptable syreadditionssalte deraf DK272182A (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27477281A 1981-06-18 1981-06-18
US34684182A 1982-02-08 1982-02-08
US35891782A 1982-03-17 1982-03-17
US35891882A 1982-03-17 1982-03-17
US06/379,557 US4543256A (en) 1982-03-17 1982-05-18 (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers

Publications (1)

Publication Number Publication Date
DK272182A true DK272182A (da) 1982-12-19

Family

ID=27540584

Family Applications (1)

Application Number Title Priority Date Filing Date
DK272182A DK272182A (da) 1981-06-18 1982-06-17 Fremgangsmaade til fremstilling af oralt effektive aporphin-forbindelser eller dopamin-agonist-forbindelser med ikke aporphinstruktur eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (8)

Country Link
CA (1) CA1270253A (fr)
DE (1) DE3222840A1 (fr)
DK (1) DK272182A (fr)
FR (1) FR2508043B1 (fr)
GB (1) GB2105323B (fr)
IE (1) IE53161B1 (fr)
IT (1) IT1191200B (fr)
NL (1) NL8202467A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012574A1 (fr) * 1989-04-25 1990-11-01 Northeastern University Composes agonistes de la dopamine
AU4536599A (en) 1999-06-21 2001-01-09 Geochemistry Research Limited Metal-rich silica products from geothermal and synthetic aqueous systems nen wie
US9359303B2 (en) 2009-04-21 2016-06-07 Purdue Research Foundation Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor
WO2020070099A1 (fr) 2018-10-02 2020-04-09 H. Lundbeck A/S Administration de promédicaments de catécholamine en combinaison avec un antagoniste de 5-ht2b

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717643A (en) * 1967-05-04 1973-02-20 Sterling Drug Inc N-substituted-norapomorphines
US3810987A (en) * 1972-06-12 1974-05-14 Merck & Co Inc Blood pressure lowering method using an aporphine

Also Published As

Publication number Publication date
GB2105323B (en) 1985-12-11
FR2508043B1 (fr) 1987-04-30
GB2105323A (en) 1983-03-23
IE821441L (en) 1982-12-18
IT1191200B (it) 1988-02-24
DE3222840A1 (de) 1983-05-05
IE53161B1 (en) 1988-08-03
FR2508043A1 (fr) 1982-12-24
IT8267776A1 (it) 1984-06-09
NL8202467A (nl) 1983-01-17
IT8267776A0 (it) 1982-06-17
CA1270253A (fr) 1990-06-12

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