DK2822965T3 - FREMGANGSMÅDE TIL BERIGELSE AF IgA - Google Patents

FREMGANGSMÅDE TIL BERIGELSE AF IgA Download PDF

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Publication number
DK2822965T3
DK2822965T3 DK13708164.2T DK13708164T DK2822965T3 DK 2822965 T3 DK2822965 T3 DK 2822965T3 DK 13708164 T DK13708164 T DK 13708164T DK 2822965 T3 DK2822965 T3 DK 2822965T3
Authority
DK
Denmark
Prior art keywords
iga
enrichment
procedure
Prior art date
Application number
DK13708164.2T
Other languages
English (en)
Inventor
Menyawi Ibrahim El
Marius Loetscher
Doreen Siegemund
Original Assignee
Csl Behring Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Csl Behring Ag filed Critical Csl Behring Ag
Application granted granted Critical
Publication of DK2822965T3 publication Critical patent/DK2822965T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • B01D15/363Anion-exchange
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
DK13708164.2T 2012-03-09 2013-03-08 FREMGANGSMÅDE TIL BERIGELSE AF IgA DK2822965T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12158927.9A EP2636681A1 (en) 2012-03-09 2012-03-09 Process for enriching IgA
PCT/EP2013/054698 WO2013132053A1 (en) 2012-03-09 2013-03-08 Process for enriching iga

Publications (1)

Publication Number Publication Date
DK2822965T3 true DK2822965T3 (da) 2022-07-11

Family

ID=47843296

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13708164.2T DK2822965T3 (da) 2012-03-09 2013-03-08 FREMGANGSMÅDE TIL BERIGELSE AF IgA

Country Status (9)

Country Link
US (1) US9828418B2 (da)
EP (2) EP2636681A1 (da)
JP (1) JP6259777B2 (da)
KR (1) KR102079487B1 (da)
CN (1) CN104245728B (da)
AU (1) AU2013201388B2 (da)
DK (1) DK2822965T3 (da)
ES (1) ES2919861T3 (da)
WO (1) WO2013132053A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2751976T3 (es) 2012-03-09 2020-04-02 Csl Behring Ag Composiciones que comprenden inmunoglobulinas de tipo secretor
EP2636684A1 (en) * 2012-03-09 2013-09-11 CSL Behring AG Prevention of infection
CN105358571B (zh) * 2013-07-01 2019-03-05 瑞士杰特贝林生物制品有限公司 方法
GB201413227D0 (en) 2014-07-25 2014-09-10 Bioproducts Lab Ltd Process
DE202014105749U1 (de) * 2014-11-27 2015-01-09 iCradle GmbH Daumenschalter zur Befestigung an einem Fahrradlenker und über einen derartigen Daumenschalter bedienbares Steuersystem für ein Fahrrad
EP3365365A4 (en) * 2015-10-21 2019-06-19 Cambryn Biologics, LLC PROCESS FOR CLEANING PROTEINS FROM PLASMA
US10829542B2 (en) 2016-12-20 2020-11-10 Csl Behring Ag Methods for affecting Salmonella infections
EP3684818A2 (en) 2017-09-21 2020-07-29 UMC Utrecht Holding B.V. Anti-gd2 antibody for the treatment of neuroblastoma
EP3794013B1 (en) * 2018-05-17 2024-02-21 CSL Behring AG Method and system of protein extraction
EP3886902A1 (en) 2018-11-30 2021-10-06 CSL Behring AG Methods and compositions for preventing or treating acute exacerbations with polyclonal immunoglobulin
KR20220004979A (ko) 2019-03-27 2022-01-12 유엠씨 우트레크트 홀딩 비.브이. 조작된 iga 항체 및 사용 방법
CN112574296B (zh) * 2020-12-30 2023-05-19 中国医学科学院输血研究所 一种模拟IVIg的多人份混合人血浆IgG样品的分离纯化方法

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US5500345A (en) * 1989-04-25 1996-03-19 Iatron Laboratories, Inc. Hybridomas producing monoclonal antibodies specific for C-reactive protein and methods for detection of C-reactive protein
DE3927111C3 (de) * 1989-08-17 1994-09-01 Biotest Pharma Gmbh Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oderIgA-haltiger Immunglobulinpräparate
US5258177A (en) * 1991-12-10 1993-11-02 Alpha Therapeutic Corporation IgA preparation and process of making the same
FR2706466B1 (fr) 1993-06-14 1995-08-25 Aetsrn Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré.
AU689489B2 (en) 1993-07-30 1998-04-02 Oravax, Inc Monoclonal IgA antibody against respiratory syncytial virus
DE19600939C1 (de) 1996-01-12 1997-08-28 Immuno Ag Verfahren zur Trennung von IgG und IgA
EP0839915A1 (en) 1996-11-01 1998-05-06 Institut Suisse De Recherches Experimentales Sur Le Cancer Isrec Secretory immunoglobulin A as a mucosal vaccine delivery system
AU8063798A (en) 1997-06-19 1999-01-04 Regents Of The University Of California, The Secretory immunoglobulin produced by single cells and methods for making and using same
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
US20020114802A1 (en) 1998-02-10 2002-08-22 Tjellstrom Bo Arthur Einar Oral immunoglobulin treatment for inflammatory bowel disease
NZ509135A (en) 1998-06-09 2002-10-25 Statens Seruminstitut A third generation intravenous immunoglobulin G (IVIG) purified using column chromatographic ion exchange methods
JP2000103800A (ja) 1998-09-29 2000-04-11 Yoshitomi Pharmaceut Ind Ltd 免疫グロブリンaの精製方法
AUPP806999A0 (en) * 1999-01-08 1999-02-04 Csl Limited Process for purifying immunoglobulins
EP1068871A1 (en) 1999-07-07 2001-01-17 Jean-Paul Perraudin Novel methods and medicament for treating infections diseases involving microbial biofilms
DE60036132T2 (de) 1999-12-13 2008-08-21 Universidad Nacional Autonoma De Mexico Quantitative immunoenzymatische messmethode
CN1312181C (zh) 2001-02-12 2007-04-25 米德列斯公司 抗Fcα受体(CD89)的人单克隆抗体
US6932967B2 (en) 2001-03-22 2005-08-23 Michael R. Simon Human medical treatment by aerosol inhalation of immunoglobulin A
FR2824568B1 (fr) 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
US20060165675A1 (en) 2002-08-02 2006-07-27 Richman-Eisenstat Janice Beth Modulation of mesenchymal cells via iga-receptors
ATE555133T1 (de) 2003-11-13 2012-05-15 Hanmi Holdings Co Ltd Igg fc fragment für einen arzneimittelträger und verfahren zu dessen herstellung
US8119104B2 (en) 2006-12-13 2012-02-21 Michael R. Simon Treatment of celiac disease with IgA
US8021645B2 (en) 2006-12-13 2011-09-20 Simon Michael R Synthesis of human secretory IgA and IgM and the formation of a medicament therefrom
US20080145420A1 (en) 2006-12-13 2008-06-19 Simon Michael R HUMAN SECRETORY IgA FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASES
US8709413B2 (en) 2006-12-13 2014-04-29 Michael R. Simon Treatment of celiac disease with IgA
US8313730B2 (en) 2006-12-13 2012-11-20 Michael R. Simon Treatment of celiac disease with IgA
US7794721B2 (en) 2006-12-13 2010-09-14 Simon Michael R Synthesis of human secretory IgM and the treatment of clostridium difficile associated diseases herewith
US7597891B2 (en) 2006-12-13 2009-10-06 Simon Michael R Synthesis of human secretory IgA for the treatment of Clostridium difficile associated diseases
EP2725035A1 (en) 2007-10-02 2014-04-30 Avaxia Biologics, Inc. Antibody therapy for use in the digestive tract
WO2009139624A1 (en) 2008-05-15 2009-11-19 Mucovax Holding B.V. Process for producing milk fractions rich in secretory immunoglobulins
GB201006753D0 (en) 2010-04-22 2010-06-09 Biotest Ag Process for preparing an immunolobulin composition
EP2465536A1 (en) 2010-12-14 2012-06-20 CSL Behring AG CD89 activation in therapy
US9442050B2 (en) * 2012-02-14 2016-09-13 Bio-Rad Laboratories, Inc. Reducing pH excursions in ion exchange chromatography using displacing counter ions
EP2636684A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Prevention of infection
EP2636683A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Treatment of mucositis with Immunoglobulin
ES2751976T3 (es) 2012-03-09 2020-04-02 Csl Behring Ag Composiciones que comprenden inmunoglobulinas de tipo secretor
US9150645B2 (en) * 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species

Also Published As

Publication number Publication date
AU2013201388B2 (en) 2015-09-03
JP2015509523A (ja) 2015-03-30
WO2013132053A1 (en) 2013-09-12
US9828418B2 (en) 2017-11-28
KR20140136028A (ko) 2014-11-27
US20150005476A1 (en) 2015-01-01
KR102079487B1 (ko) 2020-02-21
EP2636681A1 (en) 2013-09-11
CN104245728B (zh) 2017-11-28
EP2822965A1 (en) 2015-01-14
HK1202881A1 (en) 2015-10-09
ES2919861T3 (es) 2022-07-28
JP6259777B2 (ja) 2018-01-10
CN104245728A (zh) 2014-12-24
EP2822965B1 (en) 2022-05-11
AU2013201388A1 (en) 2013-09-26

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