DK2852680T3 - Fremgangsmåder og processer til ikke-invasiv evaluering af genetiske variationer - Google Patents
Fremgangsmåder og processer til ikke-invasiv evaluering af genetiske variationer Download PDFInfo
- Publication number
- DK2852680T3 DK2852680T3 DK13726373.7T DK13726373T DK2852680T3 DK 2852680 T3 DK2852680 T3 DK 2852680T3 DK 13726373 T DK13726373 T DK 13726373T DK 2852680 T3 DK2852680 T3 DK 2852680T3
- Authority
- DK
- Denmark
- Prior art keywords
- processes
- methods
- genetic variations
- invasive evaluation
- invasive
- Prior art date
Links
- 238000011156 evaluation Methods 0.000 title 1
- 230000007614 genetic variation Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6879—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for sex determination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/16—Assays for determining copy number or wherein the copy number is of special importance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261649841P | 2012-05-21 | 2012-05-21 | |
| US201261740368P | 2012-12-20 | 2012-12-20 | |
| US201261740377P | 2012-12-20 | 2012-12-20 | |
| US13/782,883 US10504613B2 (en) | 2012-12-20 | 2013-03-01 | Methods and processes for non-invasive assessment of genetic variations |
| US13/782,857 US9920361B2 (en) | 2012-05-21 | 2013-03-01 | Methods and compositions for analyzing nucleic acid |
| PCT/US2013/041906 WO2013177086A1 (en) | 2012-05-21 | 2013-05-20 | Methods and processes for non-invasive assessment of genetic variations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2852680T3 true DK2852680T3 (da) | 2020-03-16 |
Family
ID=52105674
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19219319.1T DK3663409T3 (da) | 2012-05-21 | 2013-05-20 | Fremgangsmåder og processer til ikke-invasiv bedømmelse af genetiske variationer |
| DK13726373.7T DK2852680T3 (da) | 2012-05-21 | 2013-05-20 | Fremgangsmåder og processer til ikke-invasiv evaluering af genetiske variationer |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19219319.1T DK3663409T3 (da) | 2012-05-21 | 2013-05-20 | Fremgangsmåder og processer til ikke-invasiv bedømmelse af genetiske variationer |
Country Status (5)
| Country | Link |
|---|---|
| EP (4) | EP3978621B1 (da) |
| CA (1) | CA2874195C (da) |
| DK (2) | DK3663409T3 (da) |
| ES (2) | ES2772029T3 (da) |
| WO (1) | WO2013177086A1 (da) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8962247B2 (en) | 2008-09-16 | 2015-02-24 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses |
| US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| EP2425240A4 (en) | 2009-04-30 | 2012-12-12 | Good Start Genetics Inc | METHOD AND COMPOSITION FOR EVALUATING GENETIC MARKERS |
| ES2577017T3 (es) | 2009-12-22 | 2016-07-12 | Sequenom, Inc. | Procedimientos y kits para identificar la aneuploidia |
| US9163281B2 (en) | 2010-12-23 | 2015-10-20 | Good Start Genetics, Inc. | Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction |
| WO2014014498A1 (en) * | 2012-07-20 | 2014-01-23 | Verinata Health, Inc. | Detecting and classifying copy number variation in a fetal genome |
| US20140235474A1 (en) | 2011-06-24 | 2014-08-21 | Sequenom, Inc. | Methods and processes for non invasive assessment of a genetic variation |
| US10424394B2 (en) | 2011-10-06 | 2019-09-24 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| WO2013052907A2 (en) | 2011-10-06 | 2013-04-11 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10196681B2 (en) | 2011-10-06 | 2019-02-05 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US9367663B2 (en) | 2011-10-06 | 2016-06-14 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US9984198B2 (en) | 2011-10-06 | 2018-05-29 | Sequenom, Inc. | Reducing sequence read count error in assessment of complex genetic variations |
| CA2861856C (en) | 2012-01-20 | 2020-06-02 | Sequenom, Inc. | Diagnostic processes that factor experimental conditions |
| EP2820129A1 (en) | 2012-03-02 | 2015-01-07 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US8209130B1 (en) | 2012-04-04 | 2012-06-26 | Good Start Genetics, Inc. | Sequence assembly |
| US10227635B2 (en) | 2012-04-16 | 2019-03-12 | Molecular Loop Biosolutions, Llc | Capture reactions |
| US9920361B2 (en) | 2012-05-21 | 2018-03-20 | Sequenom, Inc. | Methods and compositions for analyzing nucleic acid |
| US10504613B2 (en) | 2012-12-20 | 2019-12-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10497461B2 (en) | 2012-06-22 | 2019-12-03 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US20140093873A1 (en) | 2012-07-13 | 2014-04-03 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| CA3120521A1 (en) * | 2012-10-04 | 2014-04-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10482994B2 (en) | 2012-10-04 | 2019-11-19 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US20130309666A1 (en) | 2013-01-25 | 2013-11-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10844424B2 (en) | 2013-02-20 | 2020-11-24 | Bionano Genomics, Inc. | Reduction of bias in genomic coverage measurements |
| WO2015130696A1 (en) | 2014-02-25 | 2015-09-03 | Bionano Genomics, Inc. | Reduction of bias in genomic coverage measurements |
| CN105229168B (zh) | 2013-02-20 | 2020-07-17 | 生物纳米基因有限公司 | 纳米流体中分子的表征 |
| US11060145B2 (en) | 2013-03-13 | 2021-07-13 | Sequenom, Inc. | Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus |
| EP2971159B1 (en) | 2013-03-14 | 2019-05-08 | Molecular Loop Biosolutions, LLC | Methods for analyzing nucleic acids |
| US10930368B2 (en) | 2013-04-03 | 2021-02-23 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| KR102665592B1 (ko) * | 2013-05-24 | 2024-05-21 | 시쿼넘, 인코포레이티드 | 유전적 변이의 비침습 평가를 위한 방법 및 프로세스 |
| ES3037160T3 (en) | 2013-06-21 | 2025-09-29 | Sequenom Inc | Methods and processes for non-invasive assessment of genetic variations |
| KR102384620B1 (ko) | 2013-10-04 | 2022-04-11 | 시쿼넘, 인코포레이티드 | 유전적 변이의 비침습 평가를 위한 방법 및 프로세스 |
| CN105874082B (zh) | 2013-10-07 | 2020-06-02 | 塞昆纳姆股份有限公司 | 用于非侵入性评估染色体改变的方法和过程 |
| US10851414B2 (en) | 2013-10-18 | 2020-12-01 | Good Start Genetics, Inc. | Methods for determining carrier status |
| EP3736344A1 (en) | 2014-03-13 | 2020-11-11 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US11053548B2 (en) | 2014-05-12 | 2021-07-06 | Good Start Genetics, Inc. | Methods for detecting aneuploidy |
| EP3149640B1 (en) | 2014-05-30 | 2019-09-04 | Sequenom, Inc. | Chromosome representation determinations |
| EP4358097A1 (en) * | 2014-07-25 | 2024-04-24 | University of Washington | Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same |
| US11783911B2 (en) | 2014-07-30 | 2023-10-10 | Sequenom, Inc | Methods and processes for non-invasive assessment of genetic variations |
| WO2016025818A1 (en) | 2014-08-15 | 2016-02-18 | Good Start Genetics, Inc. | Systems and methods for genetic analysis |
| WO2016040446A1 (en) | 2014-09-10 | 2016-03-17 | Good Start Genetics, Inc. | Methods for selectively suppressing non-target sequences |
| JP2017536087A (ja) | 2014-09-24 | 2017-12-07 | グッド スタート ジェネティクス, インコーポレイテッド | 遺伝子アッセイのロバストネスを増大させるためのプロセス制御 |
| US11008606B2 (en) | 2014-10-10 | 2021-05-18 | Cold Spring Harbor Laboratory | Random nucleotide mutation for nucleotide template counting and assembly |
| EP3730629A1 (en) | 2014-10-10 | 2020-10-28 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| CA2971589C (en) | 2014-12-18 | 2021-09-28 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
| US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
| WO2016112073A1 (en) | 2015-01-06 | 2016-07-14 | Good Start Genetics, Inc. | Screening for structural variants |
| WO2017201081A1 (en) | 2016-05-16 | 2017-11-23 | Agilome, Inc. | Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids |
| EP4043581A1 (en) | 2016-05-27 | 2022-08-17 | Sequenom, Inc. | Method for generating a paralog assay system |
| CA3030890A1 (en) | 2016-07-27 | 2018-02-01 | Sequenom, Inc. | Genetic copy number alteration classifications |
| CA3030894A1 (en) | 2016-07-27 | 2018-02-01 | Sequenom, Inc. | Methods for non-invasive assessment of genomic instability |
| US10329610B2 (en) * | 2016-08-02 | 2019-06-25 | Damoun Nashtaali | Paired-end sequencing method |
| CA3049457C (en) | 2017-01-20 | 2023-05-16 | Sequenom, Inc. | Methods for non-invasive assessment of copy number alterations |
| CA3049455C (en) | 2017-01-20 | 2023-06-13 | Sequenom, Inc. | Sequencing adapter manufacture and use |
| CA3049682C (en) | 2017-01-20 | 2023-06-27 | Sequenom, Inc. | Methods for non-invasive assessment of genetic alterations |
| CA3207879A1 (en) | 2017-01-24 | 2018-08-02 | Sequenom, Inc. | Methods and processes for assessment of genetic variations |
| JP7370862B2 (ja) | 2017-03-17 | 2023-10-30 | セクエノム, インコーポレイテッド | 遺伝子モザイク症のための方法およびプロセス |
| CN110373458B (zh) * | 2019-06-27 | 2020-05-19 | 东莞博奥木华基因科技有限公司 | 一种地中海贫血检测的试剂盒及分析系统 |
| CA3159786A1 (en) | 2019-10-31 | 2021-05-06 | Sequenom, Inc. | Application of mosaicism ratio in multifetal gestations and personalized risk assessment |
| US20210189494A1 (en) * | 2019-12-18 | 2021-06-24 | The Chinese University Of Hong Kong | Cell-free dna fragmentation and nucleases |
| JP2023552015A (ja) | 2020-12-02 | 2023-12-14 | イルミナ ソフトウェア, インコーポレイテッド | 遺伝子変異を検出するためのシステム及び方法 |
| WO2024186778A1 (en) | 2023-03-03 | 2024-09-12 | Laboratory Corporation Of America Holdings | Methods and systems for positive cfdna screening on genetic variations using mosaicism ratio |
| EP4713926A1 (en) | 2023-05-15 | 2026-03-25 | Laboratory Corporation of America Holdings | Machine-learning approaches to pan-cancer screening in whole genome sequencing |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5720928A (en) | 1988-09-15 | 1998-02-24 | New York University | Image processing and analysis of individual nucleic acid molecules |
| US6927028B2 (en) | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
| CN102344960B (zh) | 2002-09-06 | 2014-06-18 | 波士顿大学信托人 | 基因表达的定量 |
| AU2003298733B2 (en) | 2002-11-27 | 2009-06-18 | Agena Bioscience, Inc. | Fragmentation-based methods and systems for sequence variation detection and discovery |
| US8048627B2 (en) | 2003-07-05 | 2011-11-01 | The Johns Hopkins University | Method and compositions for detection and enumeration of genetic variations |
| JP5149013B2 (ja) | 2004-11-29 | 2013-02-20 | セクエノム,インコーポレイティド | メチル化dnaを検出する手段、及び方法 |
| EP3617321B1 (en) | 2006-05-31 | 2024-10-23 | Sequenom, Inc. | Kit for the extraction and amplification of nucleic acid from a sample |
| JP2009540802A (ja) | 2006-06-16 | 2009-11-26 | セクエノム, インコーポレイテッド | サンプルからの核酸を増幅、検出および定量するための方法および組成物 |
| PL2557520T3 (pl) | 2007-07-23 | 2021-10-11 | The Chinese University Of Hong Kong | Określanie zaburzenia równowagi sekwencji kwasu nukleinowego |
| WO2009032779A2 (en) | 2007-08-29 | 2009-03-12 | Sequenom, Inc. | Methods and compositions for the size-specific seperation of nucleic acid from a sample |
| WO2009032781A2 (en) | 2007-08-29 | 2009-03-12 | Sequenom, Inc. | Methods and compositions for universal size-specific polymerase chain reaction |
| WO2009120808A2 (en) | 2008-03-26 | 2009-10-01 | Sequenom, Inc. | Restriction endonuclease enhanced polymorphic sequence detection |
| US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| EP3103871B1 (en) | 2008-09-16 | 2020-07-29 | Sequenom, Inc. | Processes for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for fetal nucleic acid quantification |
| WO2010065470A2 (en) * | 2008-12-01 | 2010-06-10 | Consumer Genetics, Inc. | Compositions and methods for detecting background male dna during fetal sex determination |
| EP3514244B1 (en) | 2009-04-03 | 2021-07-07 | Sequenom, Inc. | Nucleic acid preparation methods |
| EP2370599B1 (en) | 2010-01-19 | 2015-01-21 | Verinata Health, Inc | Method for determining copy number variations |
| WO2011091063A1 (en) * | 2010-01-19 | 2011-07-28 | Verinata Health, Inc. | Partition defined detection methods |
| WO2011143659A2 (en) | 2010-05-14 | 2011-11-17 | Fluidigm Corporation | Nucleic acid isolation methods |
| WO2012118745A1 (en) * | 2011-02-28 | 2012-09-07 | Arnold Oliphant | Assay systems for detection of aneuploidy and sex determination |
| WO2013019361A1 (en) | 2011-07-07 | 2013-02-07 | Life Technologies Corporation | Sequencing methods |
| JP6073902B2 (ja) * | 2011-10-06 | 2017-02-01 | セクエノム, インコーポレイテッド | 遺伝的変異の非侵襲的評価のための方法およびプロセス |
| US9367663B2 (en) | 2011-10-06 | 2016-06-14 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| ES2624686T3 (es) * | 2011-10-11 | 2017-07-17 | Sequenom, Inc. | Métodos y procesos para la evaluación no invasiva de variaciones genéticas |
| US9892230B2 (en) * | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
-
2013
- 2013-05-20 EP EP21201053.2A patent/EP3978621B1/en active Active
- 2013-05-20 EP EP23193976.0A patent/EP4276194A3/en active Pending
- 2013-05-20 EP EP19219319.1A patent/EP3663409B1/en active Active
- 2013-05-20 WO PCT/US2013/041906 patent/WO2013177086A1/en not_active Ceased
- 2013-05-20 CA CA2874195A patent/CA2874195C/en active Active
- 2013-05-20 DK DK19219319.1T patent/DK3663409T3/da active
- 2013-05-20 ES ES13726373T patent/ES2772029T3/es active Active
- 2013-05-20 EP EP13726373.7A patent/EP2852680B1/en active Active
- 2013-05-20 DK DK13726373.7T patent/DK2852680T3/da active
- 2013-05-20 ES ES19219319T patent/ES2902401T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2772029T3 (es) | 2020-07-07 |
| EP2852680A1 (en) | 2015-04-01 |
| WO2013177086A1 (en) | 2013-11-28 |
| CA2874195C (en) | 2020-08-25 |
| EP3663409B1 (en) | 2021-10-06 |
| EP3663409A1 (en) | 2020-06-10 |
| ES2902401T3 (es) | 2022-03-28 |
| CA2874195A1 (en) | 2013-11-28 |
| EP2852680B1 (en) | 2019-12-25 |
| EP3978621A1 (en) | 2022-04-06 |
| EP3978621B1 (en) | 2023-08-30 |
| HK1205203A1 (en) | 2015-12-11 |
| DK3663409T3 (da) | 2021-12-13 |
| EP4276194A3 (en) | 2024-03-06 |
| EP4276194A2 (en) | 2023-11-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL295860B1 (en) | Methods and processes for non-invasive assessment of genetic variations | |
| DK2852680T3 (da) | Fremgangsmåder og processer til ikke-invasiv evaluering af genetiske variationer | |
| IL283586A (en) | Methods and processes for non-invasive assessment of genetic variations | |
| DK2764459T3 (da) | Fremgangsmåder og processer til ikke-invasiv bedømmelse af genetiske variationer | |
| IL276761B1 (en) | Methods of inducing anesthesia | |
| DK3725807T3 (da) | Anti-cd47 antistoffer og fremgangsmåder til anvendelse deraf | |
| DK2900657T3 (da) | Cykliske etherpyrazol-4-yl-heterocyclyl-carboxamidforbindelser og fremgangsmåder til anvendelse | |
| DK2929031T5 (da) | Pcsk9-irna-sammensætninger og fremgangsmåder til anvendelse deraf | |
| DK2882496T3 (da) | Behandling og diagnosticering af melanom | |
| LT2885010T (lt) | Tautopatijos gydymo būdai | |
| DK2675827T3 (da) | Hidtil ukendte modulatorer og fremgangsmåder til anvendelse | |
| DK4389764T3 (da) | Genetisk modificerede gnavere og fremgangsmåder til anvendelse heraf | |
| DK2844292T3 (da) | ST2L-antagonister og fremgangsmåder til anvendelse | |
| HUE061261T2 (hu) | Eljárások és folyamatok genetikai variánsok nem invazív értékelésére | |
| DK2850202T3 (da) | Fremgangsmåder og grupper | |
| DK2914627T3 (da) | Anti-cd40-antistoffer og fremgangsmåder til anvendelse | |
| DK2872629T3 (da) | Tm-forstærkede blokeringsoligonukleotider og lokkemidler til forbedret target-berigesle og reduceret off-target-udvælgelse | |
| DK2806892T3 (da) | Kombineret terapeutisk anvendelse af antistoffer og endoglycosidaser | |
| DK2882441T3 (da) | Behandling af immunrelaterede og inflammatoriske sygdomme | |
| DK2840593T3 (da) | Forbedret afbryderindretning og fremgangsmåde til fremstilling dertil | |
| DK2771022T3 (da) | Cd40l-specifikke tn3-afledte skeletter (scaffolds) og fremgangsmåder til anvendelse deraf | |
| DK2492520T3 (da) | Fastgørelsesstift og fremgangsmåde til fremstilling deraf | |
| DK2896694T3 (da) | Saccharidoxidase og fremgangsmåde til fremstilling deraf og anvendelse deraf | |
| DK2852719T3 (da) | Trappeelement og fremgangsmåde til beklædning deraf | |
| DK2943460T3 (da) | 6-chlor-3-(phenyl-d5)-inden-1-on og anvendelse deraf |