DK2922571T3 - Farmaceutiske formuleringer, der omfatter carboran-holdige metallo-porphyriner - Google Patents

Farmaceutiske formuleringer, der omfatter carboran-holdige metallo-porphyriner

Info

Publication number
DK2922571T3
DK2922571T3 DK13801495.6T DK13801495T DK2922571T3 DK 2922571 T3 DK2922571 T3 DK 2922571T3 DK 13801495 T DK13801495 T DK 13801495T DK 2922571 T3 DK2922571 T3 DK 2922571T3
Authority
DK
Denmark
Prior art keywords
carboran
porphyrines
metallo
pharmaceutical formula
formula containing
Prior art date
Application number
DK13801495.6T
Other languages
English (en)
Inventor
Chris Beattie
James Rennie
Anne Wadsworth
Original Assignee
Morex Dev Partners Llp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morex Dev Partners Llp filed Critical Morex Dev Partners Llp
Application granted granted Critical
Publication of DK2922571T3 publication Critical patent/DK2922571T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK13801495.6T 2012-11-23 2013-11-22 Farmaceutiske formuleringer, der omfatter carboran-holdige metallo-porphyriner DK2922571T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1221125.6A GB201221125D0 (en) 2012-11-23 2012-11-23 Pharmaceutial formulations
PCT/EP2013/074490 WO2014079977A1 (en) 2012-11-23 2013-11-22 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
DK2922571T3 true DK2922571T3 (da) 2017-11-13

Family

ID=47560584

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13801495.6T DK2922571T3 (da) 2012-11-23 2013-11-22 Farmaceutiske formuleringer, der omfatter carboran-holdige metallo-porphyriner

Country Status (20)

Country Link
US (1) US9358290B2 (da)
EP (1) EP2922571B1 (da)
JP (1) JP6279599B2 (da)
KR (1) KR20150086283A (da)
CN (1) CN104853777B (da)
CA (1) CA2890271A1 (da)
CY (1) CY1119713T1 (da)
DK (1) DK2922571T3 (da)
ES (1) ES2646010T3 (da)
GB (1) GB201221125D0 (da)
HR (1) HRP20171652T1 (da)
HU (1) HUE035198T2 (da)
LT (1) LT2922571T (da)
NO (1) NO2922571T3 (da)
PL (1) PL2922571T3 (da)
PT (1) PT2922571T (da)
RS (1) RS56499B1 (da)
SI (1) SI2922571T1 (da)
SM (1) SMT201700512T1 (da)
WO (1) WO2014079977A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201212409D0 (en) * 2012-07-12 2012-08-22 Morex Dev Partners Llp Cancer treatment

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925736A (en) 1988-07-06 1990-05-15 Long Island Jewish Medical Center Topical hematoporphyrin
US20050090481A1 (en) 2001-11-09 2005-04-28 Qlt Inc Compositions comprising a photosensitizer and a skin-penetration enhancer and their use in photodynamic treatment
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8444953B2 (en) * 2007-03-22 2013-05-21 Brookhaven Science Associates, Llc Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof
CN101815673B (zh) * 2007-09-03 2013-07-10 Dic株式会社 纳米结构复合体覆盖型结构物的制造方法、纳米结构复合体覆盖型结构物以及使用该结构物的反应器
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
GB201212409D0 (en) * 2012-07-12 2012-08-22 Morex Dev Partners Llp Cancer treatment

Also Published As

Publication number Publication date
ES2646010T3 (es) 2017-12-11
JP6279599B2 (ja) 2018-02-14
GB201221125D0 (en) 2013-01-09
CY1119713T1 (el) 2018-06-27
PT2922571T (pt) 2017-11-07
WO2014079977A1 (en) 2014-05-30
US20150297717A1 (en) 2015-10-22
CA2890271A1 (en) 2014-05-30
HK1209339A1 (en) 2016-04-01
NO2922571T3 (da) 2018-02-03
SI2922571T1 (sl) 2017-12-29
RS56499B1 (sr) 2018-01-31
HRP20171652T1 (hr) 2017-12-15
US9358290B2 (en) 2016-06-07
EP2922571B1 (en) 2017-09-06
CN104853777B (zh) 2019-03-08
KR20150086283A (ko) 2015-07-27
SMT201700512T1 (it) 2018-01-11
EP2922571A1 (en) 2015-09-30
HUE035198T2 (hu) 2018-05-02
CN104853777A (zh) 2015-08-19
JP2016500090A (ja) 2016-01-07
PL2922571T3 (pl) 2018-03-30
LT2922571T (lt) 2017-11-10

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