DK292475A - Fremgangsmade til fremstilling af derivater af 3-amino-2-hydroxy-1-phenoxy-propan - Google Patents

Fremgangsmade til fremstilling af derivater af 3-amino-2-hydroxy-1-phenoxy-propan

Info

Publication number
DK292475A
DK292475A DK292475A DK292475A DK292475A DK 292475 A DK292475 A DK 292475A DK 292475 A DK292475 A DK 292475A DK 292475 A DK292475 A DK 292475A DK 292475 A DK292475 A DK 292475A
Authority
DK
Denmark
Prior art keywords
phenoxy
hydroxy
amino
preparing
procedure
Prior art date
Application number
DK292475A
Other languages
English (en)
Other versions
DK143555B (da
DK143555C (da
Inventor
H Demarne
Original Assignee
Cm Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cm Ind filed Critical Cm Ind
Publication of DK292475A publication Critical patent/DK292475A/da
Publication of DK143555B publication Critical patent/DK143555B/da
Application granted granted Critical
Publication of DK143555C publication Critical patent/DK143555C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK292475A 1974-06-28 1975-06-27 Analogifremgangsmaade til fremstilling af 5-fluor-2-(2-hydroxy-3-tert.-butylaminopropoxy)-butyrophenon eller syreadditionssalte eller optisk aktive isomere heraf DK143555C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB28925/74A GB1501632A (en) 1974-06-28 1974-06-28 Aromatic ketones having cardiovascular activity
GB2892574 1974-06-28

Publications (3)

Publication Number Publication Date
DK292475A true DK292475A (da) 1975-12-29
DK143555B DK143555B (da) 1981-09-07
DK143555C DK143555C (da) 1982-02-01

Family

ID=10283421

Family Applications (1)

Application Number Title Priority Date Filing Date
DK292475A DK143555C (da) 1974-06-28 1975-06-27 Analogifremgangsmaade til fremstilling af 5-fluor-2-(2-hydroxy-3-tert.-butylaminopropoxy)-butyrophenon eller syreadditionssalte eller optisk aktive isomere heraf

Country Status (17)

Country Link
US (2) US4252825A (da)
JP (2) JPS5826743B2 (da)
AR (1) AR205388A1 (da)
AT (1) AT343098B (da)
BE (1) BE830766A (da)
CA (1) CA1052820A (da)
CS (1) CS197248B2 (da)
DE (1) DE2528147A1 (da)
DK (1) DK143555C (da)
ES (1) ES438931A1 (da)
FR (1) FR2276032A1 (da)
GB (1) GB1501632A (da)
IE (1) IE41386B1 (da)
NL (1) NL7507703A (da)
SE (2) SE416546B (da)
YU (1) YU165775A (da)
ZA (1) ZA754141B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1501632A (en) * 1974-06-28 1978-02-22 Cm Ind Aromatic ketones having cardiovascular activity
JPH0516363Y2 (da) * 1986-08-01 1993-04-28
EA200500234A1 (ru) 2002-08-19 2005-08-25 Пфайзер Продактс Инк. Комбинированная терапия гиперпролиферативных болезней
SG141430A1 (en) * 2003-05-30 2008-04-28 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as hmg-co inhibitors
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
BRPI0618379A2 (pt) * 2005-11-08 2011-08-30 Ranbaxy Lab Ltd processo para preparação do hemi-sal de cálcio do ácido (3r,5r) -7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroxime tilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
AR059838A1 (es) * 2006-03-14 2008-04-30 Ranbaxy Lab Ltd Formulaciones para dosis estabilizantes de estatina
AU2007274724B2 (en) * 2006-07-14 2012-07-26 Ranbaxy Laboratories Limited Polymorphic forms of an HMG-CoA reductase inhibitor and uses thereof
ATE547394T1 (de) 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
WO2020150473A2 (en) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Pcsk9 inhibitors and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL301580A (da) * 1962-12-11
US3637852A (en) * 1963-08-26 1972-01-25 Boehringer Sohn Ingelheim 1-phenoxy-2-hydroxy-3-isopropylamino-propanes and salts thereof
DE1493454C3 (de) * 1963-08-26 1980-04-30 C.H. Boehringer Sohn, 6507 Ingelheim 1 -Aryloxy^-hydroxy-S-isopropylaminopropane und deren Salze sowie deren Herstellung und darauf basierende Arzneimittel
GB1231783A (en) * 1967-05-16 1971-05-12 May & Baker Ltd Benzene derivatives
JPS512115B2 (da) * 1971-09-28 1976-01-23
JPS4911847A (da) * 1972-05-20 1974-02-01
GB1501632A (en) * 1974-06-28 1978-02-22 Cm Ind Aromatic ketones having cardiovascular activity

Also Published As

Publication number Publication date
FR2276032B1 (da) 1979-08-10
JPS58140050A (ja) 1983-08-19
SE7812646L (sv) 1978-12-08
IE41386B1 (en) 1979-12-19
US4252825A (en) 1981-02-24
SE416546B (sv) 1981-01-19
US4302601A (en) 1981-11-24
CS197248B2 (en) 1980-04-30
AT343098B (de) 1978-05-10
JPS5929574B2 (ja) 1984-07-21
JPS5123233A (en) 1976-02-24
AU8256675A (en) 1977-01-06
BE830766A (fr) 1975-12-29
IE41386L (en) 1975-12-28
GB1501632A (en) 1978-02-22
SE7507359L (sv) 1975-12-29
NL7507703A (nl) 1975-12-30
DE2528147A1 (de) 1976-01-15
ATA497275A (de) 1977-09-15
AR205388A1 (es) 1976-04-30
SE417087B (sv) 1981-02-23
DK143555B (da) 1981-09-07
DK143555C (da) 1982-02-01
JPS5826743B2 (ja) 1983-06-04
FR2276032A1 (fr) 1976-01-23
ES438931A1 (es) 1977-05-16
ZA754141B (en) 1976-06-30
CA1052820A (en) 1979-04-17
YU165775A (en) 1982-02-28

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Legal Events

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PBP Patent lapsed