DK2976359T4 - Fremgangsmåder til behandling af osteogenesis imperfecta - Google Patents

Fremgangsmåder til behandling af osteogenesis imperfecta Download PDF

Info

Publication number: DK2976359T4
Authority: DK; Denmark
Prior art keywords: procedures; treatment; osteogenesis imperfecta; imperfecta; osteogenesis
Prior art date: 2013-03-20

Application number

DK14717386.8T

Other languages

English (en)

Other versions

DK2976359T3 (da

Inventor

Brendan Lee

Kuber T Sampath

Original Assignee

Genzyme Corp

Baylor College Medicine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-03-20

Filing date

2014-03-20

Publication date

2022-06-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50483613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2976359(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2014-03-20 Application filed by Genzyme Corp, Baylor College Medicine filed Critical Genzyme Corp

2019-01-02 Application granted granted Critical

2019-01-02 Publication of DK2976359T3 publication Critical patent/DK2976359T3/da

2022-06-13 Publication of DK2976359T4 publication Critical patent/DK2976359T4/da

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Mycology (AREA)
Microbiology (AREA)
Physical Education & Sports Medicine (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Endocrinology (AREA)
Inorganic Chemistry (AREA)
Pulmonology (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)

DK14717386.8T 2013-03-20 2014-03-20 Fremgangsmåder til behandling af osteogenesis imperfecta DK2976359T4 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201361803647P	2013-03-20	2013-03-20
US201361875399P	2013-09-09	2013-09-09
US201361883151P	2013-09-26	2013-09-26
PCT/US2014/031279 WO2014153435A1 (en)	2013-03-20	2014-03-20	Methods for treating osteogenesis imperfecta

Publications (2)

Publication Number	Publication Date
DK2976359T3 DK2976359T3 (da)	2019-01-02
DK2976359T4 true DK2976359T4 (da)	2022-06-13

Family

ID=50483613

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK14717386.8T DK2976359T4 (da)	2013-03-20	2014-03-20	Fremgangsmåder til behandling af osteogenesis imperfecta
DK17206987.4T DK3312195T3 (da)	2013-03-20	2014-03-20	Fremgangsmåder til behandling af osteogenesis imperfecta

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK17206987.4T DK3312195T3 (da)	2013-03-20	2014-03-20	Fremgangsmåder til behandling af osteogenesis imperfecta

Country Status (26)

Country	Link
US (4)	US9598486B2 (da)
EP (3)	EP3312195B1 (da)
JP (3)	JP6483086B2 (da)
KR (1)	KR102257138B1 (da)
CN (2)	CN111000997A (da)
AU (1)	AU2014235933B2 (da)
CA (1)	CA2907422C (da)
CL (1)	CL2015002801A1 (da)
DK (2)	DK2976359T4 (da)
EA (1)	EA032327B1 (da)
ES (2)	ES2763869T3 (da)
HR (2)	HRP20181939T4 (da)
HU (1)	HUE046702T2 (da)
IL (2)	IL241461B (da)
LT (2)	LT2976359T (da)
MX (2)	MX369360B (da)
MY (1)	MY172324A (da)
PH (2)	PH12015501864A1 (da)
PL (2)	PL2976359T5 (da)
PT (2)	PT3312195T (da)
RS (2)	RS59673B1 (da)
SG (2)	SG10201701985YA (da)
SI (2)	SI2976359T2 (da)
TW (1)	TWI629995B (da)
UY (1)	UY35493A (da)
WO (1)	WO2014153435A1 (da)

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AU2014235933B2 (en) *	2013-03-20	2019-01-24	Baylor College Of Medicine	Methods for treating osteogenesis imperfecta
TWI733661B (zh) *	2015-03-04	2021-07-21	美商健臻公司	以高親合性、結合性及特異性結合轉化生長因子－β１的經修飾ＩｇＧ抗體
TWI726870B (zh)	2015-03-04	2021-05-11	美商健臻公司	具有高親和性、結合性及專一性之結合轉形生長因子-β１的ｓｃＦｖ-Ｆｃ二聚體
US20190216943A1 (en) *	2016-08-11	2019-07-18	Precithera, Inc.	Tgf-beta antagonist conjugates
CN106755395B (zh) *	2016-12-16	2020-05-12	山东第一医科大学(山东省医学科学院)	Xi型成骨不全致病基因fkbp10的突变位点及其应用
AR110904A1 (es) *	2017-01-20	2019-05-15	Sanofi Sa	ANTICUERPOS ANTI-TGF-b Y SU USO
TW202506185A (zh)	2017-01-20	2025-02-16	法商賽諾菲公司	抗TGF-β抗體及其用途
EP3571227A1 (en) *	2017-01-20	2019-11-27	Sanofi	Anti-tgf-beta antibodies and their use
AR110755A1 (es) *	2017-01-20	2019-05-02	Genzyme Corp	Anticuerpos dirigidos a hueso
WO2019113123A1 (en) *	2017-12-04	2019-06-13	Precithera, Inc.	TGF-ß RECEPTOR FUSION PROTEINS AND OTHER TGF-ß ANTAGONISTS FOR REDUCING TGF-ß SIGNALING
BR112021000065A2 (pt)	2018-07-10	2021-04-06	Sanofi	Terapias de combinação contra câncer direcionando cd38 e tgf-beta
MY204234A (en)	2018-08-27	2024-08-16	Regeneron Pharma	Use of raman spectroscopy in downstream purification
CN110916855A (zh) *	2018-09-20	2020-03-27	天津正天医疗器械有限公司	一种仿生多孔椎间植入物及其制造方法
AU2021365528A1 (en) *	2020-10-23	2023-06-15	Hq Han	Bifunctional antagonists of tumor necrosis factor-alpha and transforming growth factor-beta and uses thereof
KR20240018471A (ko) *	2021-05-07	2024-02-13	베이롤 칼리지 오브 메드신	중등증 내지 중증 불완전 골형성증의 치료
CN113501879B (zh) *	2021-06-30	2022-09-06	拜盖特生物科技(上海)有限公司	一种解除肿瘤免疫微环境中免疫抑制的双功能抗体及其应用和制备方法
US20230144192A1 (en) *	2021-11-01	2023-05-11	Genzyme Corporation	Treatment of osteogenesis imperfecta
EP4649098A1 (en) *	2023-01-13	2025-11-19	Shanghai Kaijin Biotechnology , Ltd	Multi-specific polypeptide complexes
CN120290673A (zh) *	2025-04-02	2025-07-11	湖北省农业科学院农产品加工与核农技术研究所	一种抗光老化胶原多肽的制备方法和应用

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AU2014235933B2 (en) *	2013-03-20	2019-01-24	Baylor College Of Medicine	Methods for treating osteogenesis imperfecta

2014
- 2014-03-20 AU AU2014235933A patent/AU2014235933B2/en active Active
- 2014-03-20 SG SG10201701985YA patent/SG10201701985YA/en unknown
- 2014-03-20 RS RS20191624A patent/RS59673B1/sr unknown
- 2014-03-20 DK DK14717386.8T patent/DK2976359T4/da active
- 2014-03-20 EA EA201591843A patent/EA032327B1/ru not_active IP Right Cessation
- 2014-03-20 WO PCT/US2014/031279 patent/WO2014153435A1/en not_active Ceased
- 2014-03-20 LT LTEP14717386.8T patent/LT2976359T/lt unknown
- 2014-03-20 RS RS20181438A patent/RS58188B2/sr unknown
- 2014-03-20 ES ES17206987T patent/ES2763869T3/es active Active
- 2014-03-20 EP EP17206987.4A patent/EP3312195B1/en active Active
- 2014-03-20 CN CN201910988588.9A patent/CN111000997A/zh active Pending
- 2014-03-20 MY MYPI2015702733A patent/MY172324A/en unknown
- 2014-03-20 PL PL14717386.8T patent/PL2976359T5/pl unknown
- 2014-03-20 HU HUE17206987A patent/HUE046702T2/hu unknown
- 2014-03-20 CN CN201480028990.8A patent/CN105229028B/zh active Active
- 2014-03-20 TW TW103110468A patent/TWI629995B/zh active
- 2014-03-20 JP JP2016504355A patent/JP6483086B2/ja active Active
- 2014-03-20 PL PL17206987T patent/PL3312195T3/pl unknown
- 2014-03-20 ES ES14717386T patent/ES2700238T5/es active Active
- 2014-03-20 US US14/772,708 patent/US9598486B2/en active Active
- 2014-03-20 MX MX2015013402A patent/MX369360B/es active IP Right Grant
- 2014-03-20 PT PT172069874T patent/PT3312195T/pt unknown
- 2014-03-20 PT PT14717386T patent/PT2976359T/pt unknown
- 2014-03-20 SI SI201430985T patent/SI2976359T2/sl unknown
- 2014-03-20 HR HRP20181939TT patent/HRP20181939T4/hr unknown
- 2014-03-20 CA CA2907422A patent/CA2907422C/en active Active
- 2014-03-20 EP EP19194235.8A patent/EP3640260A1/en not_active Withdrawn
- 2014-03-20 LT LTEP17206987.4T patent/LT3312195T/lt unknown
- 2014-03-20 UY UY0001035493A patent/UY35493A/es not_active Application Discontinuation
- 2014-03-20 EP EP14717386.8A patent/EP2976359B2/en active Active
- 2014-03-20 SI SI201431435T patent/SI3312195T1/sl unknown
- 2014-03-20 DK DK17206987.4T patent/DK3312195T3/da active
- 2014-03-20 KR KR1020157028130A patent/KR102257138B1/ko active Active
- 2014-03-20 SG SG11201506683XA patent/SG11201506683XA/en unknown
- 2014-03-20 MX MX2019009122A patent/MX389759B/es unknown
2015
- 2015-08-25 PH PH12015501864A patent/PH12015501864A1/en unknown
- 2015-09-10 IL IL241461A patent/IL241461B/en unknown
- 2015-09-17 CL CL2015002801A patent/CL2015002801A1/es unknown
2017
- 2017-02-08 US US15/427,920 patent/US10377819B2/en active Active
2019
- 2019-02-06 PH PH12019500261A patent/PH12019500261B1/en unknown
- 2019-02-12 JP JP2019022397A patent/JP6677837B2/ja active Active
- 2019-07-01 US US16/459,023 patent/US11230595B2/en active Active
- 2019-12-17 HR HRP20192277TT patent/HRP20192277T1/hr unknown
2020
- 2020-03-12 JP JP2020042524A patent/JP7016113B2/ja active Active
2021
- 2021-11-08 IL IL287915A patent/IL287915A/en unknown
- 2021-12-09 US US17/547,069 patent/US12365725B2/en active Active

Also Published As

Publication number	Publication date
EP3312195A1 (en)	2018-04-25
JP2016519093A (ja)	2016-06-30
MX389759B (es)	2025-03-20
KR20150132262A (ko)	2015-11-25
SG10201701985YA (en)	2017-04-27
IL287915A (en)	2022-01-01
US20190389943A1 (en)	2019-12-26
PH12015501864B1 (en)	2015-12-07
DK3312195T3 (da)	2020-01-06
US9598486B2 (en)	2017-03-21
PL3312195T3 (pl)	2020-04-30
HRP20181939T1 (hr)	2019-01-25
PL2976359T5 (pl)	2022-07-18
EP2976359B2 (en)	2022-03-23
TWI629995B (zh)	2018-07-21
ES2700238T3 (es)	2019-02-14
CL2015002801A1 (es)	2016-08-12
JP2019089826A (ja)	2019-06-13
US12365725B2 (en)	2025-07-22
EA032327B1 (ru)	2019-05-31
PT2976359T (pt)	2018-12-05
CN105229028A (zh)	2016-01-06
MY172324A (en)	2019-11-21
LT3312195T (lt)	2020-01-10
US20170247439A1 (en)	2017-08-31
JP2020109110A (ja)	2020-07-16
AU2014235933B2 (en)	2019-01-24
UY35493A (es)	2014-11-28
EP2976359B1 (en)	2018-08-29
DK2976359T3 (da)	2019-01-02
HK1213576A1 (en)	2016-07-08
US10377819B2 (en)	2019-08-13
US11230595B2 (en)	2022-01-25
BR112015023905A2 (pt)	2017-10-24
EA201591843A1 (ru)	2016-01-29
SI2976359T2 (sl)	2022-05-31
CN105229028B (zh)	2019-11-08
RS58188B2 (sr)	2022-06-30
PT3312195T (pt)	2019-12-23
JP6677837B2 (ja)	2020-04-08
US20220195025A1 (en)	2022-06-23
EP2976359A1 (en)	2016-01-27
CN111000997A (zh)	2020-04-14
PH12019500261B1 (en)	2021-03-26
PH12015501864A1 (en)	2015-12-07
WO2014153435A1 (en)	2014-09-25
RS58188B1 (sr)	2019-03-29
NZ712353A (en)	2021-04-30
RS59673B1 (sr)	2020-01-31
US20160031979A1 (en)	2016-02-04
ES2700238T5 (es)	2022-05-20
IL241461A0 (en)	2015-11-30
CA2907422A1 (en)	2014-09-25
HRP20192277T1 (hr)	2020-03-06
AU2014235933A1 (en)	2015-10-01
LT2976359T (lt)	2018-12-27
EP3312195B1 (en)	2019-10-09
SI2976359T1 (sl)	2019-03-29
IL241461B (en)	2021-12-01
HRP20181939T4 (hr)	2022-05-13
SI3312195T1 (sl)	2020-02-28
HK1253717A1 (en)	2019-06-28
CA2907422C (en)	2021-08-31
KR102257138B1 (ko)	2021-05-26
TW201524515A (zh)	2015-07-01
JP6483086B2 (ja)	2019-03-13
JP7016113B2 (ja)	2022-02-04
MX2015013402A (es)	2016-01-08
PL2976359T3 (pl)	2019-03-29
MX2019009122A (es)	2019-09-16
MX369360B (es)	2019-11-06
SG11201506683XA (en)	2015-09-29
HUE046702T2 (hu)	2020-03-30
ES2763869T3 (es)	2020-06-01
EP3640260A1 (en)	2020-04-22
PH12019500261A1 (en)	2020-07-20

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