DK3002009T3 - Behandling af imatinib-resistent kronisk myeloid leukæmi, som har mutationen 1457t>c i bcrabl-genet, under anvendelse af forbindelsen bosutinib - Google Patents

Behandling af imatinib-resistent kronisk myeloid leukæmi, som har mutationen 1457t>c i bcrabl-genet, under anvendelse af forbindelsen bosutinib Download PDF

Info

Publication number: DK3002009T3
Authority: DK; Denmark
Prior art keywords: bcrabl; bosutinib; imatinib; genet; mutation
Prior art date: 2007-06-01

Application number

DK15191756.4T

Other languages

English (en)

Inventor

Becker Hewes

Original Assignee

Wyeth Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-01

Filing date

2008-05-30

Publication date

2021-08-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39639071&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3002009(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-05-30 Application filed by Wyeth Llc filed Critical Wyeth Llc

2021-08-02 Application granted granted Critical

2021-08-02 Publication of DK3002009T3 publication Critical patent/DK3002009T3/da

Links

WEVYNIUIFUYDGI-UHFFFAOYSA-N 3-[6-[4-(trifluoromethoxy)anilino]-4-pyrimidinyl]benzamide Chemical compound NC(=O)C1=CC=CC(C=2N=CN=C(NC=3C=CC(OC(F)(F)F)=CC=3)C=2)=C1 WEVYNIUIFUYDGI-UHFFFAOYSA-N 0.000 title 1
208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 title 1
-1 BOSUTINIB COMPOUND Chemical class 0.000 title 1
208000010833 Chronic myeloid leukaemia Diseases 0.000 title 1
239000002145 L01XE14 - Bosutinib Substances 0.000 title 1
208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 title 1
229960003736 bosutinib Drugs 0.000 title 1
230000035772 mutation Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Quinoline Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK15191756.4T 2007-06-01 2008-05-30 Behandling af imatinib-resistent kronisk myeloid leukæmi, som har mutationen 1457t>c i bcrabl-genet, under anvendelse af forbindelsen bosutinib DK3002009T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US93265007P	2007-06-01	2007-06-01
EP08769857A EP2152267A2 (en)	2007-06-01	2008-05-30	Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles

Publications (1)

Publication Number	Publication Date
DK3002009T3 true DK3002009T3 (da)	2021-08-02

Family

ID=39639071

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK12160638.8T DK2478905T3 (da)	2007-06-01	2008-05-30	Behandling af imatinib-resistent leukæmi under anvendelse af 4-aminoquinolin-3-carbonitriler
DK15191756.4T DK3002009T3 (da)	2007-06-01	2008-05-30	Behandling af imatinib-resistent kronisk myeloid leukæmi, som har mutationen 1457t>c i bcrabl-genet, under anvendelse af forbindelsen bosutinib

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK12160638.8T DK2478905T3 (da)	2007-06-01	2008-05-30	Behandling af imatinib-resistent leukæmi under anvendelse af 4-aminoquinolin-3-carbonitriler

Country Status (23)

Country	Link
US (1)	US11103497B2 (da)
EP (4)	EP2152267A2 (da)
JP (3)	JP5888853B2 (da)
KR (1)	KR101493543B1 (da)
CN (1)	CN101686973B (da)
AU (1)	AU2008260070B9 (da)
BR (1)	BRPI0812355A2 (da)
CA (3)	CA2964162C (da)
CL (1)	CL2008001577A1 (da)
CY (2)	CY1115251T1 (da)
DK (2)	DK2478905T3 (da)
ES (2)	ES2881391T3 (da)
HU (1)	HUE055524T2 (da)
IL (1)	IL202407A0 (da)
MX (1)	MX2009013069A (da)
PA (1)	PA8782301A1 (da)
PL (2)	PL2478905T3 (da)
PT (2)	PT2478905E (da)
RU (1)	RU2464026C2 (da)
SI (2)	SI2478905T1 (da)
TW (1)	TW200908982A (da)
WO (1)	WO2008150957A2 (da)
ZA (1)	ZA200908480B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2964162C (en)	2007-06-01	2019-12-31	Wyeth Llc	Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles having mutation in the bcrabl gene
SG192769A1 (en)	2011-03-04	2013-09-30	Glaxosmithkline Ip No 2 Ltd	Amino-quinolines as kinase inhibitors
TWI547494B (zh)	2011-08-18	2016-09-01	葛蘭素史克智慧財產發展有限公司	作為激酶抑制劑之胺基喹唑啉類
AR092529A1 (es)	2012-09-13	2015-04-22	Glaxosmithkline Llc	Compuesto de aminoquinazolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento
AR092530A1 (es)	2012-09-13	2015-04-22	Glaxosmithkline Llc	Compuesto de amino-quinolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento
RU2662810C2 (ru)	2013-02-21	2018-07-31	Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед	Хиназолины в качестве ингибиторов киназы
KR101733665B1 (ko)	2015-05-06	2017-05-10	재단법인 지능형 바이오 시스템 설계 및 합성 연구단	진세노사이드 Ｆ1 또는 Ｒｇ3을 유효성분으로 포함하는 글리벡 내성 백혈병 예방 또는 치료용 약학 조성물
JP2022544700A (ja) *	2019-08-22	2022-10-20	バイオヘイブン・セラピューティクス・リミテッド	筋萎縮性側索硬化症および関連障害の治療のためにｔｄｐ－４３に結合する分子
CN115944636A (zh) *	2022-11-01	2023-04-11	华南师范大学	博舒替尼在抑制i-motif结构上的应用
WO2025024311A2 (en) *	2023-07-21	2025-01-30	Icahn School Of Medicine At Mount Sinai	G9a/glp inhibitors and methods of use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6002008A (en)	1997-04-03	1999-12-14	American Cyanamid Company	Substituted 3-cyano quinolines
US6297258B1 (en)	1998-09-29	2001-10-02	American Cyanamid Company	Substituted 3-cyanoquinolines
AU2002245296B2 (en) *	2001-01-25	2006-12-21	Bristol-Myers Squibb Company	Methods of administering epothilone analogs for the treatment of cancer
PT2017335E (pt)	2001-10-05	2011-03-02	Novartis Ag	Domínios da cinase abl mutados
TWI275390B (en) *	2002-04-30	2007-03-11	Wyeth Corp	Process for the preparation of 7-substituted-3- quinolinecarbonitriles
US20050010780A1 (en) *	2003-07-09	2005-01-13	Kane John Richard	Method and apparatus for providing access to personal information
EP1680119A1 (en) *	2003-11-06	2006-07-19	Wyeth	4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml)
NL1031674C2 (nl)	2005-04-25	2007-04-26	Pfizer	Antilichamen tegen myostatine.
DE602006014540D1 (en) *	2005-05-16	2010-07-08	Irm Llc	Pyrrolopyridinderivate als proteinkinaseinhibitoren
EP1904654A2 (en)	2005-07-15	2008-04-02	Brystol-Myers Squibb Company	Methods of identifying and treating individuals exhibiting mutant src kinase polypeptides
BRPI0616923A2 (pt)	2005-10-06	2011-07-05	Lilly Co Eli	anticorpos monoclonais, seus usos e composição farmacêutica
EP1948820A2 (en) *	2005-11-04	2008-07-30	Bristol-Myers Squibb Pharma Company	T315a and f317i mutations of bcr-abl kinase domain
CA2964162C (en)	2007-06-01	2019-12-31	Wyeth Llc	Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles having mutation in the bcrabl gene

2008
- 2008-05-30 CA CA2964162A patent/CA2964162C/en active Active
- 2008-05-30 SI SI200831212T patent/SI2478905T1/sl unknown
- 2008-05-30 WO PCT/US2008/065215 patent/WO2008150957A2/en not_active Ceased
- 2008-05-30 EP EP08769857A patent/EP2152267A2/en not_active Withdrawn
- 2008-05-30 MX MX2009013069A patent/MX2009013069A/es active IP Right Grant
- 2008-05-30 TW TW097120369A patent/TW200908982A/zh unknown
- 2008-05-30 PT PT121606388T patent/PT2478905E/pt unknown
- 2008-05-30 HU HUE15191756A patent/HUE055524T2/hu unknown
- 2008-05-30 PT PT151917564T patent/PT3002009T/pt unknown
- 2008-05-30 PL PL12160638T patent/PL2478905T3/pl unknown
- 2008-05-30 CN CN2008800219346A patent/CN101686973B/zh active Active
- 2008-05-30 EP EP15191756.4A patent/EP3002009B1/en active Active
- 2008-05-30 RU RU2009144128/15A patent/RU2464026C2/ru active
- 2008-05-30 ES ES15191756T patent/ES2881391T3/es active Active
- 2008-05-30 EP EP12160638.8A patent/EP2478905B1/en active Active
- 2008-05-30 PA PA20088782301A patent/PA8782301A1/es unknown
- 2008-05-30 SI SI200832178T patent/SI3002009T1/sl unknown
- 2008-05-30 CA CA2868899A patent/CA2868899C/en active Active
- 2008-05-30 KR KR1020097027540A patent/KR101493543B1/ko active Active
- 2008-05-30 DK DK12160638.8T patent/DK2478905T3/da active
- 2008-05-30 CL CL200801577A patent/CL2008001577A1/es unknown
- 2008-05-30 AU AU2008260070A patent/AU2008260070B9/en active Active
- 2008-05-30 ES ES12160638.8T patent/ES2477567T3/es active Active
- 2008-05-30 EP EP14167958.9A patent/EP2777704A3/en not_active Withdrawn
- 2008-05-30 BR BRPI0812355-1A2A patent/BRPI0812355A2/pt not_active Application Discontinuation
- 2008-05-30 US US12/129,935 patent/US11103497B2/en active Active
- 2008-05-30 DK DK15191756.4T patent/DK3002009T3/da active
- 2008-05-30 JP JP2010510505A patent/JP5888853B2/ja active Active
- 2008-05-30 PL PL15191756T patent/PL3002009T3/pl unknown
- 2008-05-30 CA CA2688467A patent/CA2688467C/en active Active
2009
- 2009-11-29 IL IL202407A patent/IL202407A0/en unknown
- 2009-11-30 ZA ZA200908480A patent/ZA200908480B/xx unknown
2014
- 2014-01-31 JP JP2014016309A patent/JP2014111629A/ja active Pending
- 2014-06-03 CY CY20141100395T patent/CY1115251T1/el unknown
2015
- 2015-11-24 JP JP2015229117A patent/JP2016074700A/ja active Pending
2021
- 2021-08-03 CY CY20211100693T patent/CY1124391T1/el unknown

Also Published As

Publication number	Publication date
SI3002009T1 (sl)	2021-09-30
RU2009144128A (ru)	2011-07-20
RU2464026C2 (ru)	2012-10-20
PA8782301A1 (es)	2009-01-23
IL202407A0 (en)	2010-06-30
HK1142812A1 (en)	2010-12-17
EP3002009A3 (en)	2016-07-06
BRPI0812355A2 (pt)	2015-01-27
CN101686973A (zh)	2010-03-31
CA2964162C (en)	2019-12-31
CY1124391T1 (el)	2022-07-22
EP3002009A2 (en)	2016-04-06
TW200908982A (en)	2009-03-01
MX2009013069A (es)	2010-03-17
EP2152267A2 (en)	2010-02-17
ES2881391T3 (es)	2021-11-29
CY1115251T1 (el)	2017-01-04
CA2688467C (en)	2015-05-12
JP2010529038A (ja)	2010-08-26
EP2777704A2 (en)	2014-09-17
AU2008260070B2 (en)	2011-08-18
KR20100017983A (ko)	2010-02-16
CA2868899C (en)	2017-06-13
EP2478905A3 (en)	2013-01-16
ES2477567T3 (es)	2014-07-17
JP2016074700A (ja)	2016-05-12
AU2008260070B9 (en)	2012-01-19
ZA200908480B (en)	2010-08-25
US11103497B2 (en)	2021-08-31
CA2688467A1 (en)	2008-12-11
EP3002009B1 (en)	2021-07-07
CA2964162A1 (en)	2008-12-11
HUE055524T2 (hu)	2021-11-29
PL2478905T3 (pl)	2014-10-31
WO2008150957A3 (en)	2009-08-06
JP5888853B2 (ja)	2016-03-22
PL3002009T3 (pl)	2021-12-13
KR101493543B1 (ko)	2015-02-13
US20080318971A1 (en)	2008-12-25
SI2478905T1 (sl)	2014-07-31
CA2868899A1 (en)	2008-12-11
EP2478905B1 (en)	2014-05-14
AU2008260070A1 (en)	2008-12-11
PT2478905E (pt)	2014-07-16
JP2014111629A (ja)	2014-06-19
CN101686973B (zh)	2013-06-19
DK2478905T3 (da)	2014-06-30
WO2008150957A2 (en)	2008-12-11
EP2777704A3 (en)	2015-01-21
CL2008001577A1 (es)	2008-07-25
PT3002009T (pt)	2021-08-02
EP2478905A2 (en)	2012-07-25

Publication	Publication Date	Title
DK3002009T3 (da)	2021-08-02	Behandling af imatinib-resistent kronisk myeloid leukæmi, som har mutationen 1457t>c i bcrabl-genet, under anvendelse af forbindelsen bosutinib
SMP200900085B (it)	2010-11-12	3-imidazolil-indoli per il trattamento di malattieproliferative.
LTC2109608I2 (lt)	2019-05-10	Amidu pakeisti indazolai, kaip poli(ADP-ribozės)polimerazės (PARP) inhibitoriai
DK2504005T3 (da)	2014-01-13	Anvendelse af 1,3-diphenylprop-2-en-1-on-derivater til behandling af lever-sygdomme
SG2014015085A (en)	2014-06-27	2,6-diamino-pyrimidin-5-yl-carboxamides as syk or jak kinases inhibitors
IL208638A0 (en)	2010-12-30	2,6-diamino-pyrimidin-5-yl-carboxamides as syk or jak kinases inhibitors
PL3354276T3 (pl)	2020-09-21	Kompozycje do leczenia zapalenia przewodu pokarmowego
DK2307393T3 (da)	2013-07-15	Fremgangsmåde til fremstilling af apoptosepromotoren ABT-263
DK3517534T3 (da)	2024-05-27	Forbindelser, der er anvendelige til behandling af cancer
ITMI20071002A1 (it)	2008-11-18	Manufatto per edilizia.
DK2358698T3 (da)	2012-10-08	Tetrasubstitueret pyridazin som hedgehog-pathway antagonister
IL274522A (en)	2020-06-30	2,6-diamino-pyrimidin-5-yl-carboxamides as inhibitors of SYK or JAK kinases
IT1398496B1 (it)	2013-03-01	Struttura modulare automontante per la costituzione di ambienti protetti.
CL2008000110A1 (es)	2008-05-16	Uso de compuestos derivados de piranona sustituidos para el tratamiento del sindrome metabolico; y compuestos derivados de piranona sustituidos.
WO2010039885A3 (en)	2010-06-24	Crystalline forms of dexlansoprazole
EP2220015A4 (en)	2012-12-12	AZEOTROPÄHNLICHE COMPOSITIONS OF 1,1,2,3,3-PENTAFLUORPROPEN
ITRM20080037A1 (it)	2009-07-24	Procedimento per la ultrapurificazione di alginati.
BRPI0912193A2 (pt)	2015-10-06	compostos terapêuticos.
ITPD20080026U1 (it)	2009-10-17	Tavolo ribaltabile
TH0701001229B (th)	2016-04-26	เฮทเทอโรเพนตะไซเคิล (heteropentacycles) ที่ว่องไวในฐานะสารยับยั้งไคเนส (kinase inhibitors)
IT1392013B1 (it)	2012-02-09	Gamba per tavolo.
IT1391925B1 (it)	2012-02-02	Apparato per il trattamento di fluidi, particolarmente in costruzioni navali.
ITMI20080126A1 (it)	2009-07-29	Struttura di bottone rimovibile.
ITRM20080027A1 (it)	2009-07-19	Uso di aciclovir per il trattamento delle condilomatosi.
TH103091B (th)	2010-07-30	เครื่องฉีดน้ำช่วยระบายความร้อน