PT3002009T - Tratamento de leucemia mielógena crónica resistente a imatinib tendo amutação 1457t>c no gene bcrabl utilizando o composto bosutinib - Google Patents

Tratamento de leucemia mielógena crónica resistente a imatinib tendo amutação 1457t>c no gene bcrabl utilizando o composto bosutinib

Info

Publication number: PT3002009T
Authority: PT; Portugal
Prior art keywords: carbonitriles; aminoquinoline; treatment; resistant leukemia; imatinib resistant
Prior art date: 2007-06-01

Application number

PT151917564T

Other languages

English (en)

Original Assignee

Wyeth Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-01

Filing date

2008-05-30

Publication date

2021-08-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39639071&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3002009(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-05-30 Application filed by Wyeth Llc filed Critical Wyeth Llc

2021-08-02 Publication of PT3002009T publication Critical patent/PT3002009T/pt

Links

239000005517 L01XE01 - Imatinib Substances 0.000 title 1
KTUFNOKKBVMGRW-UHFFFAOYSA-N imatinib Chemical compound C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 KTUFNOKKBVMGRW-UHFFFAOYSA-N 0.000 title 1
229960002411 imatinib Drugs 0.000 title 1
208000032839 leukemia Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Quinoline Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PT151917564T 2007-06-01 2008-05-30 Tratamento de leucemia mielógena crónica resistente a imatinib tendo amutação 1457t>c no gene bcrabl utilizando o composto bosutinib PT3002009T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US93265007P	2007-06-01	2007-06-01

Publications (1)

Publication Number	Publication Date
PT3002009T true PT3002009T (pt)	2021-08-02

Family

ID=39639071

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PT151917564T PT3002009T (pt)	2007-06-01	2008-05-30	Tratamento de leucemia mielógena crónica resistente a imatinib tendo amutação 1457t>c no gene bcrabl utilizando o composto bosutinib
PT121606388T PT2478905E (pt)	2007-06-01	2008-05-30	Tratamento de leucemia resistente a imatinib utilizando 4- aminoquinoleína-3-carbonitrilos

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PT121606388T PT2478905E (pt)	2007-06-01	2008-05-30	Tratamento de leucemia resistente a imatinib utilizando 4- aminoquinoleína-3-carbonitrilos

Country Status (23)

Country	Link
US (1)	US11103497B2 (pt)
EP (4)	EP2777704A3 (pt)
JP (3)	JP5888853B2 (pt)
KR (1)	KR101493543B1 (pt)
CN (1)	CN101686973B (pt)
AU (1)	AU2008260070B9 (pt)
BR (1)	BRPI0812355A2 (pt)
CA (3)	CA2688467C (pt)
CL (1)	CL2008001577A1 (pt)
CY (2)	CY1115251T1 (pt)
DK (2)	DK2478905T3 (pt)
ES (2)	ES2881391T3 (pt)
HU (1)	HUE055524T2 (pt)
IL (1)	IL202407A0 (pt)
MX (1)	MX2009013069A (pt)
PA (1)	PA8782301A1 (pt)
PL (2)	PL3002009T3 (pt)
PT (2)	PT3002009T (pt)
RU (1)	RU2464026C2 (pt)
SI (2)	SI3002009T1 (pt)
TW (1)	TW200908982A (pt)
WO (1)	WO2008150957A2 (pt)
ZA (1)	ZA200908480B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2777704A3 (en) *	2007-06-01	2015-01-21	Wyeth LLC	Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles
JP6026441B2 (ja)	2011-03-04	2016-11-16	グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅＩｎｔｅｌｌｅｃｔｕａｌＰｒｏｐｅｒｔｙＤｅｖｅｌｏｐｍｅｎｔＬｉｍｉｔｅｄ	キナーゼ阻害剤としてのアミノキノリン
TWI547494B (zh)	2011-08-18	2016-09-01	葛蘭素史克智慧財產發展有限公司	作為激酶抑制劑之胺基喹唑啉類
AR092529A1 (es)	2012-09-13	2015-04-22	Glaxosmithkline Llc	Compuesto de aminoquinazolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento
AR092530A1 (es)	2012-09-13	2015-04-22	Glaxosmithkline Llc	Compuesto de amino-quinolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento
CN105143208B (zh)	2013-02-21	2017-09-26	葛兰素史密斯克莱知识产权发展有限公司	作为激酶抑制剂的喹唑啉
KR101733665B1 (ko) *	2015-05-06	2017-05-10	재단법인 지능형 바이오 시스템 설계 및 합성 연구단	진세노사이드 Ｆ1 또는 Ｒｇ3을 유효성분으로 포함하는 글리벡 내성 백혈병 예방 또는 치료용 약학 조성물
JP2022544700A (ja) *	2019-08-22	2022-10-20	バイオヘイブン・セラピューティクス・リミテッド	筋萎縮性側索硬化症および関連障害の治療のためにｔｄｐ－４３に結合する分子
CN115944636A (zh) *	2022-11-01	2023-04-11	华南师范大学	博舒替尼在抑制i-motif结构上的应用
EP4746884A2 (en) *	2023-07-21	2026-05-27	Icahn School of Medicine at Mount Sinai	G9a/glp inhibitors and methods of use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6002008A (en)	1997-04-03	1999-12-14	American Cyanamid Company	Substituted 3-cyano quinolines
US6297258B1 (en)	1998-09-29	2001-10-02	American Cyanamid Company	Substituted 3-cyanoquinolines
CA2434526C (en) *	2001-01-25	2011-11-01	Bristol Myers Squibb Company	Methods of administering epothilone analogs for the treatment of cancer
EP2341133A1 (en)	2001-10-05	2011-07-06	Novartis AG	Mutated Abl kinase domains
TWI275390B (en) *	2002-04-30	2007-03-11	Wyeth Corp	Process for the preparation of 7-substituted-3- quinolinecarbonitriles
US20050010780A1 (en) *	2003-07-09	2005-01-13	Kane John Richard	Method and apparatus for providing access to personal information
CA2543163A1 (en)	2003-11-06	2005-05-26	Wyeth	4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml)
TW200724548A (en)	2005-04-25	2007-07-01	Pfizer	Antibodies to myostatin
AU2006247322A1 (en) *	2005-05-16	2006-11-23	Irm Llc	Pyrrolopyridine derivatives as protein kinase inhibitors
AU2006270187A1 (en)	2005-07-15	2007-01-25	Bristol-Myers Squibb Company	Methods of identifying and treating individuals exhibiting mutant SRC kinase polypeptides
KR101135220B1 (ko)	2005-10-06	2012-04-24	일라이 릴리 앤드 캄파니	항-마이오스타틴 항체
WO2007056177A2 (en) *	2005-11-04	2007-05-18	Bristol-Myers Squibb Pharma Company	T315a and f317i mutations of bcr-abl kinase domain
EP2777704A3 (en) *	2007-06-01	2015-01-21	Wyeth LLC	Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles

2008
- 2008-05-30 EP EP14167958.9A patent/EP2777704A3/en not_active Withdrawn
- 2008-05-30 JP JP2010510505A patent/JP5888853B2/ja active Active
- 2008-05-30 BR BRPI0812355-1A2A patent/BRPI0812355A2/pt not_active Application Discontinuation
- 2008-05-30 PT PT151917564T patent/PT3002009T/pt unknown
- 2008-05-30 CA CA2688467A patent/CA2688467C/en active Active
- 2008-05-30 EP EP15191756.4A patent/EP3002009B1/en active Active
- 2008-05-30 US US12/129,935 patent/US11103497B2/en active Active
- 2008-05-30 CN CN2008800219346A patent/CN101686973B/zh active Active
- 2008-05-30 RU RU2009144128/15A patent/RU2464026C2/ru active
- 2008-05-30 CL CL200801577A patent/CL2008001577A1/es unknown
- 2008-05-30 SI SI200832178T patent/SI3002009T1/sl unknown
- 2008-05-30 DK DK12160638.8T patent/DK2478905T3/da active
- 2008-05-30 CA CA2868899A patent/CA2868899C/en active Active
- 2008-05-30 PA PA20088782301A patent/PA8782301A1/es unknown
- 2008-05-30 CA CA2964162A patent/CA2964162C/en active Active
- 2008-05-30 TW TW097120369A patent/TW200908982A/zh unknown
- 2008-05-30 PL PL15191756T patent/PL3002009T3/pl unknown
- 2008-05-30 WO PCT/US2008/065215 patent/WO2008150957A2/en not_active Ceased
- 2008-05-30 MX MX2009013069A patent/MX2009013069A/es active IP Right Grant
- 2008-05-30 PL PL12160638T patent/PL2478905T3/pl unknown
- 2008-05-30 ES ES15191756T patent/ES2881391T3/es active Active
- 2008-05-30 KR KR1020097027540A patent/KR101493543B1/ko active Active
- 2008-05-30 EP EP08769857A patent/EP2152267A2/en not_active Withdrawn
- 2008-05-30 SI SI200831212T patent/SI2478905T1/sl unknown
- 2008-05-30 ES ES12160638.8T patent/ES2477567T3/es active Active
- 2008-05-30 AU AU2008260070A patent/AU2008260070B9/en active Active
- 2008-05-30 DK DK15191756.4T patent/DK3002009T3/da active
- 2008-05-30 PT PT121606388T patent/PT2478905E/pt unknown
- 2008-05-30 EP EP12160638.8A patent/EP2478905B1/en active Active
- 2008-05-30 HU HUE15191756A patent/HUE055524T2/hu unknown
2009
- 2009-11-29 IL IL202407A patent/IL202407A0/en unknown
- 2009-11-30 ZA ZA200908480A patent/ZA200908480B/xx unknown
2014
- 2014-01-31 JP JP2014016309A patent/JP2014111629A/ja active Pending
- 2014-06-03 CY CY20141100395T patent/CY1115251T1/el unknown
2015
- 2015-11-24 JP JP2015229117A patent/JP2016074700A/ja active Pending
2021
- 2021-08-03 CY CY20211100693T patent/CY1124391T1/el unknown

Also Published As

Publication number	Publication date
EP2478905A2 (en)	2012-07-25
HUE055524T2 (hu)	2021-11-29
RU2009144128A (ru)	2011-07-20
CY1124391T1 (el)	2022-07-22
EP3002009B1 (en)	2021-07-07
CN101686973A (zh)	2010-03-31
JP2014111629A (ja)	2014-06-19
RU2464026C2 (ru)	2012-10-20
CA2964162A1 (en)	2008-12-11
EP3002009A3 (en)	2016-07-06
AU2008260070B2 (en)	2011-08-18
DK2478905T3 (da)	2014-06-30
IL202407A0 (en)	2010-06-30
EP2777704A2 (en)	2014-09-17
AU2008260070A1 (en)	2008-12-11
EP2478905A3 (en)	2013-01-16
HK1142812A1 (en)	2010-12-17
CN101686973B (zh)	2013-06-19
PA8782301A1 (es)	2009-01-23
WO2008150957A3 (en)	2009-08-06
US11103497B2 (en)	2021-08-31
ZA200908480B (en)	2010-08-25
AU2008260070B9 (en)	2012-01-19
US20080318971A1 (en)	2008-12-25
JP5888853B2 (ja)	2016-03-22
TW200908982A (en)	2009-03-01
PL2478905T3 (pl)	2014-10-31
WO2008150957A2 (en)	2008-12-11
BRPI0812355A2 (pt)	2015-01-27
CA2964162C (en)	2019-12-31
CY1115251T1 (el)	2017-01-04
EP2777704A3 (en)	2015-01-21
SI2478905T1 (sl)	2014-07-31
DK3002009T3 (da)	2021-08-02
ES2881391T3 (es)	2021-11-29
CA2688467C (en)	2015-05-12
JP2010529038A (ja)	2010-08-26
EP2152267A2 (en)	2010-02-17
KR101493543B1 (ko)	2015-02-13
JP2016074700A (ja)	2016-05-12
CL2008001577A1 (es)	2008-07-25
PL3002009T3 (pl)	2021-12-13
EP2478905B1 (en)	2014-05-14
CA2868899A1 (en)	2008-12-11
EP3002009A2 (en)	2016-04-06
CA2868899C (en)	2017-06-13
SI3002009T1 (sl)	2021-09-30
PT2478905E (pt)	2014-07-16
KR20100017983A (ko)	2010-02-16
CA2688467A1 (en)	2008-12-11
MX2009013069A (es)	2010-03-17
ES2477567T3 (es)	2014-07-17

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ZA201000614B (en)	2011-11-30	Antiviral compounds
GB0714485D0 (en)	2007-09-05	Stimulator
EP2234623A4 (en)	2012-03-28	ANTIVIRAL CONNECTIONS
GB0718255D0 (en)	2007-10-31	Nucleobase characterisation
GB0711342D0 (en)	2007-07-25	Well treatment
GB0810364D0 (en)	2008-07-09	Improved effluent treatment
ZA201000225B (en)	2011-03-30	Treatment of depression
GB2455402B (en)	2010-05-05	Stimulation aid
GB0701145D0 (en)	2007-02-28	Freedom shower
GB0716784D0 (en)	2007-10-10	Well treatment
EP2176303A4 (en)	2010-09-01	MODIFICATION OF POLYOLEFINS
EG25492A (en)	2012-01-15	Defoliant
GB0723100D0 (en)	2008-01-02	Treatment of HFnEF
GB0723609D0 (en)	2008-01-09	Antiviral
GB0705204D0 (en)	2007-04-25	Uses of (S)-clenbuterol
AU3967P (en)	2010-02-03	CARDINAL Cordyline australis
GB0707534D0 (en)	2007-05-30	Enhanced fixation aids
AU318763S (en)	2008-04-08	Ceramic tub
GB0724838D0 (en)	2008-01-30	Effulent treatment
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