PL2478905T3 - Sposób leczenia białaczki opornej na imatynib, wykorzystujący 4-aminochinolino-3-karbonitryle - Google Patents

Sposób leczenia białaczki opornej na imatynib, wykorzystujący 4-aminochinolino-3-karbonitryle

Info

Publication number
PL2478905T3
PL2478905T3 PL12160638T PL12160638T PL2478905T3 PL 2478905 T3 PL2478905 T3 PL 2478905T3 PL 12160638 T PL12160638 T PL 12160638T PL 12160638 T PL12160638 T PL 12160638T PL 2478905 T3 PL2478905 T3 PL 2478905T3
Authority
PL
Poland
Prior art keywords
carbonitriles
aminoquinoline
treatment
resistant leukemia
imatinib resistant
Prior art date
Application number
PL12160638T
Other languages
English (en)
Inventor
Becker Hewes
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39639071&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2478905(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of PL2478905T3 publication Critical patent/PL2478905T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL12160638T 2007-06-01 2008-05-30 Sposób leczenia białaczki opornej na imatynib, wykorzystujący 4-aminochinolino-3-karbonitryle PL2478905T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93265007P 2007-06-01 2007-06-01
EP08769857A EP2152267A2 (en) 2007-06-01 2008-05-30 Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles
EP12160638.8A EP2478905B1 (en) 2007-06-01 2008-05-30 Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles

Publications (1)

Publication Number Publication Date
PL2478905T3 true PL2478905T3 (pl) 2014-10-31

Family

ID=39639071

Family Applications (2)

Application Number Title Priority Date Filing Date
PL15191756T PL3002009T3 (pl) 2007-06-01 2008-05-30 Leczenie przewlekłej białaczki szpikowej opornej na imatynib z mutacją 1457T>C w genie bcrabl, wykorzystujące bosutynib
PL12160638T PL2478905T3 (pl) 2007-06-01 2008-05-30 Sposób leczenia białaczki opornej na imatynib, wykorzystujący 4-aminochinolino-3-karbonitryle

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL15191756T PL3002009T3 (pl) 2007-06-01 2008-05-30 Leczenie przewlekłej białaczki szpikowej opornej na imatynib z mutacją 1457T>C w genie bcrabl, wykorzystujące bosutynib

Country Status (23)

Country Link
US (1) US11103497B2 (pl)
EP (4) EP3002009B1 (pl)
JP (3) JP5888853B2 (pl)
KR (1) KR101493543B1 (pl)
CN (1) CN101686973B (pl)
AU (1) AU2008260070B9 (pl)
BR (1) BRPI0812355A2 (pl)
CA (3) CA2688467C (pl)
CL (1) CL2008001577A1 (pl)
CY (2) CY1115251T1 (pl)
DK (2) DK2478905T3 (pl)
ES (2) ES2477567T3 (pl)
HU (1) HUE055524T2 (pl)
IL (1) IL202407A0 (pl)
MX (1) MX2009013069A (pl)
PA (1) PA8782301A1 (pl)
PL (2) PL3002009T3 (pl)
PT (2) PT3002009T (pl)
RU (1) RU2464026C2 (pl)
SI (2) SI3002009T1 (pl)
TW (1) TW200908982A (pl)
WO (1) WO2008150957A2 (pl)
ZA (1) ZA200908480B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200908982A (en) * 2007-06-01 2009-03-01 Wyeth Corp Treatment of imatinib resistant leukemia
WO2012122011A2 (en) 2011-03-04 2012-09-13 Glaxosmithkline Llc Amino-quinolines as kinase inhibitors
TWI547494B (zh) 2011-08-18 2016-09-01 葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之胺基喹唑啉類
TW201425307A (zh) 2012-09-13 2014-07-01 Glaxosmithkline Llc 作為激酶抑制劑之胺基-喹啉類
TWI592417B (zh) 2012-09-13 2017-07-21 葛蘭素史克智慧財產發展有限公司 胺基喹唑啉激酶抑制劑之前藥
TWI630203B (zh) 2013-02-21 2018-07-21 葛蘭素史克智慧財產發展有限公司 做為激酶抑制劑的喹唑啉類
KR101733665B1 (ko) * 2015-05-06 2017-05-10 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 진세노사이드 F1 또는 Rg3을 유효성분으로 포함하는 글리벡 내성 백혈병 예방 또는 치료용 약학 조성물
PH12022550370A1 (en) * 2019-08-22 2023-03-06 Biohaven Therapeutics Ltd Molecules that bind to tdp-43 for the treatment of amyotrophic lateral sclerosis and related disorders
CN115944636A (zh) * 2022-11-01 2023-04-11 华南师范大学 博舒替尼在抑制i-motif结构上的应用
WO2025024311A2 (en) * 2023-07-21 2025-01-30 Icahn School Of Medicine At Mount Sinai G9a/glp inhibitors and methods of use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002008A (en) 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
US6297258B1 (en) 1998-09-29 2001-10-02 American Cyanamid Company Substituted 3-cyanoquinolines
PL207720B1 (pl) * 2001-01-25 2011-01-31 Bristol Myers Squibb Co Sposób przygotowania preparatu farmaceutycznego i jego zastosowanie, farmaceutyczny produkt oraz sposób wytwarzania kompozycji farmaceutycznej
EP2290056A3 (en) * 2001-10-05 2011-06-01 Novartis AG Mutated Abl kinase domains
TWI275390B (en) * 2002-04-30 2007-03-11 Wyeth Corp Process for the preparation of 7-substituted-3- quinolinecarbonitriles
US20050010780A1 (en) * 2003-07-09 2005-01-13 Kane John Richard Method and apparatus for providing access to personal information
BRPI0416289A (pt) * 2003-11-06 2007-01-23 Wyeth Corp 4-anilino-3-quinolinacarbonitrilas para o tratamento de leucemia mielógeno crÈnica (cml)
EP1877075A4 (en) 2005-04-25 2008-07-30 Pfizer ANTIBODY TO MYOSTATIN
BRPI0610828A2 (pt) * 2005-05-16 2010-07-27 Irm Llc compostos e composições como inibidores de proteìna quinase
WO2007011765A2 (en) 2005-07-15 2007-01-25 Bristol-Myers Squibb Company Methods of identifying and treating individuals exhibiting mutant src kinase polypeptides
ES2533464T3 (es) 2005-10-06 2015-04-10 Eli Lilly And Company Anticuerpos anti-miostatina
US20100029676A1 (en) 2005-11-04 2010-02-04 Sawyers Charles L T315a and f317i mutations of bcr-abl kinase domain
TW200908982A (en) * 2007-06-01 2009-03-01 Wyeth Corp Treatment of imatinib resistant leukemia

Also Published As

Publication number Publication date
CN101686973B (zh) 2013-06-19
AU2008260070B9 (en) 2012-01-19
BRPI0812355A2 (pt) 2015-01-27
EP2478905A2 (en) 2012-07-25
DK3002009T3 (da) 2021-08-02
HUE055524T2 (hu) 2021-11-29
EP3002009B1 (en) 2021-07-07
CL2008001577A1 (es) 2008-07-25
RU2464026C2 (ru) 2012-10-20
DK2478905T3 (da) 2014-06-30
KR101493543B1 (ko) 2015-02-13
EP2152267A2 (en) 2010-02-17
EP3002009A2 (en) 2016-04-06
CY1124391T1 (el) 2022-07-22
JP2016074700A (ja) 2016-05-12
ES2477567T3 (es) 2014-07-17
HK1142812A1 (en) 2010-12-17
CA2868899C (en) 2017-06-13
EP2478905A3 (en) 2013-01-16
CN101686973A (zh) 2010-03-31
JP2010529038A (ja) 2010-08-26
IL202407A0 (en) 2010-06-30
AU2008260070A1 (en) 2008-12-11
SI3002009T1 (sl) 2021-09-30
CA2868899A1 (en) 2008-12-11
SI2478905T1 (sl) 2014-07-31
CA2688467C (en) 2015-05-12
ZA200908480B (en) 2010-08-25
US20080318971A1 (en) 2008-12-25
AU2008260070B2 (en) 2011-08-18
PA8782301A1 (es) 2009-01-23
PL3002009T3 (pl) 2021-12-13
PT3002009T (pt) 2021-08-02
RU2009144128A (ru) 2011-07-20
JP5888853B2 (ja) 2016-03-22
TW200908982A (en) 2009-03-01
EP2478905B1 (en) 2014-05-14
EP2777704A2 (en) 2014-09-17
PT2478905E (pt) 2014-07-16
CA2964162C (en) 2019-12-31
CA2964162A1 (en) 2008-12-11
JP2014111629A (ja) 2014-06-19
EP3002009A3 (en) 2016-07-06
WO2008150957A3 (en) 2009-08-06
EP2777704A3 (en) 2015-01-21
MX2009013069A (es) 2010-03-17
KR20100017983A (ko) 2010-02-16
US11103497B2 (en) 2021-08-31
CY1115251T1 (el) 2017-01-04
WO2008150957A2 (en) 2008-12-11
CA2688467A1 (en) 2008-12-11
ES2881391T3 (es) 2021-11-29

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