DK3058092T3 - Fremgangsmåder og præparater til fremstilling af nukleinsyrebiblioteker - Google Patents
Fremgangsmåder og præparater til fremstilling af nukleinsyrebiblioteker Download PDFInfo
- Publication number
- DK3058092T3 DK3058092T3 DK14796335.9T DK14796335T DK3058092T3 DK 3058092 T3 DK3058092 T3 DK 3058092T3 DK 14796335 T DK14796335 T DK 14796335T DK 3058092 T3 DK3058092 T3 DK 3058092T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparations
- methods
- nucleic acid
- acid libraries
- preparing nucleic
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361892220P | 2013-10-17 | 2013-10-17 | |
| US201361914204P | 2013-12-10 | 2013-12-10 | |
| PCT/US2014/060942 WO2015057985A1 (en) | 2013-10-17 | 2014-10-16 | Methods and compositions for preparing nucleic acid libraries |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3058092T3 true DK3058092T3 (da) | 2019-08-19 |
Family
ID=51871288
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19167673.3T DK3572527T3 (da) | 2013-10-17 | 2014-10-16 | Fremgangsmåder og præparater til fremstilling af nukleinsyrebiblioteker |
| DK14796335.9T DK3058092T3 (da) | 2013-10-17 | 2014-10-16 | Fremgangsmåder og præparater til fremstilling af nukleinsyrebiblioteker |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19167673.3T DK3572527T3 (da) | 2013-10-17 | 2014-10-16 | Fremgangsmåder og præparater til fremstilling af nukleinsyrebiblioteker |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US10294511B2 (da) |
| EP (3) | EP3572527B1 (da) |
| DK (2) | DK3572527T3 (da) |
| ES (1) | ES2885191T3 (da) |
| HU (1) | HUE045954T2 (da) |
| WO (1) | WO2015057985A1 (da) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| CA2865575C (en) | 2012-02-27 | 2024-01-16 | Cellular Research, Inc. | Compositions and kits for molecular counting |
| US9567645B2 (en) | 2013-08-28 | 2017-02-14 | Cellular Research, Inc. | Massively parallel single cell analysis |
| US20150353989A1 (en) * | 2014-06-09 | 2015-12-10 | Illumina Cambridge Limited | Sample preparation for nucleic acid amplification |
| WO2016004368A2 (en) * | 2014-07-03 | 2016-01-07 | Rhodx, Inc. | Tagging and assessing a target sequence |
| CN107208158B (zh) | 2015-02-27 | 2022-01-28 | 贝克顿迪金森公司 | 空间上可寻址的分子条形编码 |
| EP3835431B1 (en) | 2015-03-30 | 2022-11-02 | Becton, Dickinson and Company | Methods for combinatorial barcoding |
| US11390914B2 (en) | 2015-04-23 | 2022-07-19 | Becton, Dickinson And Company | Methods and compositions for whole transcriptome amplification |
| CN107922966B (zh) | 2015-07-06 | 2022-06-28 | 伊卢米纳剑桥有限公司 | 用于核酸扩增的样品制备 |
| JP6940484B2 (ja) | 2015-09-11 | 2021-09-29 | セルラー リサーチ， インコーポレイテッド | ライブラリー正規化のための方法および組成物 |
| ES2964592T3 (es) * | 2015-11-05 | 2024-04-08 | Global Life Sciences Solutions Operations UK Ltd | Circularización y amplificación de ácido nucleico asistida por ligasa |
| US20190106746A1 (en) * | 2016-03-15 | 2019-04-11 | Georgetown University | Next-generation sequencing to identify abo blood group |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| AU2017331459B2 (en) | 2016-09-26 | 2023-04-13 | Becton, Dickinson And Company | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
| JP6941680B2 (ja) | 2016-10-24 | 2021-09-29 | ジェネインフォセック、インコーポレイテッド | 核酸内に存在する情報の秘匿化 |
| KR102061396B1 (ko) * | 2016-11-04 | 2019-12-31 | 울산대학교 산학협력단 | 엔도뉴클레이즈를 이용한 ffpe 조직 유래 dna 라이브러리 제작 방법 |
| US11359192B1 (en) * | 2016-11-04 | 2022-06-14 | Genopeaks Co., Ltd. | Method for preparing DNA library derived from FFPE tissue using endonuclease |
| CN110382708A (zh) | 2017-02-01 | 2019-10-25 | 赛卢拉研究公司 | 使用阻断性寡核苷酸进行选择性扩增 |
| US10689684B2 (en) | 2017-02-14 | 2020-06-23 | Microsoft Technology Licensing, Llc | Modifications to polynucleotides for sequencing |
| US10930370B2 (en) | 2017-03-03 | 2021-02-23 | Microsoft Technology Licensing, Llc | Polynucleotide sequencer tuned to artificial polynucleotides |
| CN108624584A (zh) * | 2017-03-16 | 2018-10-09 | 上海融享生物科技有限公司 | 一种针对ctDNA低频检测的文库构建方法 |
| WO2018226293A1 (en) | 2017-06-05 | 2018-12-13 | Becton, Dickinson And Company | Sample indexing for single cells |
| WO2019070598A1 (en) * | 2017-10-04 | 2019-04-11 | Toma Biosciences, Inc. | PREPARATION OF LIBRARIES FOR GENOME SEQUENCING |
| AU2019249422B2 (en) | 2018-04-02 | 2025-09-25 | Grail, Inc. | Methylation markers and targeted methylation probe panels |
| EP3788171B1 (en) | 2018-05-03 | 2023-04-05 | Becton, Dickinson and Company | High throughput multiomics sample analysis |
| EP3788170B1 (en) | 2018-05-03 | 2025-01-01 | Becton, Dickinson and Company | Molecular barcoding on opposite transcript ends |
| IL281741B2 (en) | 2018-09-27 | 2026-04-01 | Grail Inc | Methylation markers and a targeted methylation detection panel |
| WO2020072380A1 (en) | 2018-10-01 | 2020-04-09 | Cellular Research, Inc. | Determining 5' transcript sequences |
| US11926821B2 (en) | 2018-10-22 | 2024-03-12 | The Chinese University Of Hong Kong | Cell-free DNA quality |
| EP3877520B1 (en) | 2018-11-08 | 2025-03-19 | Becton, Dickson And Company | Whole transcriptome analysis of single cells using random priming |
| EP4745247A2 (en) | 2018-12-13 | 2026-05-20 | Becton Dickinson Co | SELECTIVE EXTENSION IN A SINGLE-CELL WHOLE-TRANSCRIPTOME ANALYSIS |
| CN113574178B (zh) | 2019-01-23 | 2024-10-29 | 贝克顿迪金森公司 | 与抗体关联的寡核苷酸 |
| CN120099139A (zh) | 2019-02-14 | 2025-06-06 | 贝克顿迪金森公司 | 杂合体靶向和全转录物组扩增 |
| WO2020236939A2 (en) | 2019-05-23 | 2020-11-26 | Paradigm Diagnostics | Tissue preparation using nuclease |
| CN120099137A (zh) | 2019-07-22 | 2025-06-06 | 贝克顿迪金森公司 | 单细胞染色质免疫沉淀测序测定 |
| GB201911515D0 (en) * | 2019-08-12 | 2019-09-25 | Univ London Queen Mary | Methods for generating a population of polynucleotide molecules |
| CN110511978A (zh) * | 2019-09-09 | 2019-11-29 | 北京优迅医学检验实验室有限公司 | Ffpe样本dna文库及其构建方法 |
| CN110669830B (zh) * | 2019-10-24 | 2023-05-23 | 裕策医疗器械江苏有限公司 | 一种低质量ffpe dna的处理方法、装置和存储介质 |
| EP4055160B1 (en) | 2019-11-08 | 2024-04-10 | Becton Dickinson and Company | Using random priming to obtain full-length v(d)j information for immune repertoire sequencing |
| WO2021095866A1 (ja) | 2019-11-15 | 2021-05-20 | 花王株式会社 | シーケンシング用ライブラリの調製方法 |
| WO2021146219A1 (en) | 2020-01-13 | 2021-07-22 | Becton, Dickinson And Company | Cell capture using du-containing oligonucleotides |
| EP4090763B1 (en) | 2020-01-13 | 2024-12-04 | Becton Dickinson and Company | Methods and compositions for quantitation of proteins and rna |
| ES2993319T3 (en) | 2020-01-29 | 2024-12-27 | Becton Dickinson Co | Barcoded wells for spatial mapping of single cells through sequencing |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| CN115151810A (zh) | 2020-02-25 | 2022-10-04 | 贝克顿迪金森公司 | 实现使用单细胞样品作为单色补偿对照的双特异性探针 |
| US11661625B2 (en) | 2020-05-14 | 2023-05-30 | Becton, Dickinson And Company | Primers for immune repertoire profiling |
| CN115803445A (zh) | 2020-06-02 | 2023-03-14 | 贝克顿迪金森公司 | 用于5撇基因表达测定的寡核苷酸和珠 |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| WO2022026909A1 (en) | 2020-07-31 | 2022-02-03 | Becton, Dickinson And Company | Single cell assay for transposase-accessible chromatin |
| US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| EP4259819A4 (en) * | 2020-12-11 | 2024-11-20 | The Broad Institute Inc. | DUPLEX REPAIR PROCESS |
| US12392771B2 (en) | 2020-12-15 | 2025-08-19 | Becton, Dickinson And Company | Single cell secretome analysis |
| CN112680794A (zh) * | 2020-12-28 | 2021-04-20 | 深圳海普洛斯医学检验实验室 | 一种应用于ngs平台的超微量核酸样本建库方法 |
| EP4215619A1 (en) * | 2022-01-21 | 2023-07-26 | Genomill Health Oy | Methods for sensitive and accurate parallel quantification of nucleic acids |
| CA3265783A1 (en) * | 2022-08-31 | 2024-03-07 | Saga Diagnostics Ab | PREPARATION OF BANK PACKS FROM FIXED SAMPLES |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5714330A (en) | 1994-04-04 | 1998-02-03 | Lynx Therapeutics, Inc. | DNA sequencing by stepwise ligation and cleavage |
| CA2195562A1 (en) | 1994-08-19 | 1996-02-29 | Pe Corporation (Ny) | Coupled amplification and ligation method |
| US5695934A (en) | 1994-10-13 | 1997-12-09 | Lynx Therapeutics, Inc. | Massively parallel sequencing of sorted polynucleotides |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US6969488B2 (en) | 1998-05-22 | 2005-11-29 | Solexa, Inc. | System and apparatus for sequential processing of analytes |
| CA2305449A1 (en) | 1997-10-10 | 1999-04-22 | President & Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US6485944B1 (en) | 1997-10-10 | 2002-11-26 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US6511803B1 (en) | 1997-10-10 | 2003-01-28 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US6787308B2 (en) | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| WO2001023610A2 (en) | 1999-09-29 | 2001-04-05 | Solexa Ltd. | Polynucleotide sequencing |
| GB0127564D0 (en) | 2001-11-16 | 2002-01-09 | Medical Res Council | Emulsion compositions |
| CA2513889A1 (en) | 2003-01-29 | 2004-08-19 | 454 Corporation | Double ended sequencing |
| CA2531105C (en) | 2003-07-05 | 2015-03-17 | The Johns Hopkins University | Method and compositions for detection and enumeration of genetic variations |
| EP2272983A1 (en) | 2005-02-01 | 2011-01-12 | AB Advanced Genetic Analysis Corporation | Reagents, methods and libraries for bead-based sequencing |
| AU2006259565B2 (en) | 2005-06-15 | 2011-01-06 | Complete Genomics, Inc. | Single molecule arrays for genetic and chemical analysis |
| JP5654749B2 (ja) | 2006-04-11 | 2015-01-14 | ニユー・イングランド・バイオレイブス・インコーポレイテツド | 改良された増幅のための核酸の修復 |
| EP2079838A1 (en) * | 2006-05-16 | 2009-07-22 | NuGEN Technologies, Inc. | Nucleic acid separation and purification method based on reversible charge interactions |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| EP2639578B1 (en) | 2006-12-14 | 2016-09-14 | Life Technologies Corporation | Apparatus for measuring analytes using large scale fet arrays |
| US7862999B2 (en) * | 2007-01-17 | 2011-01-04 | Affymetrix, Inc. | Multiplex targeted amplification using flap nuclease |
| WO2009012984A1 (en) * | 2007-07-26 | 2009-01-29 | Roche Diagnostics Gmbh | Target preparation for parallel sequencing of complex genomes |
| US20100301398A1 (en) | 2009-05-29 | 2010-12-02 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| US20100137143A1 (en) | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| WO2011019964A1 (en) * | 2009-08-12 | 2011-02-17 | Nugen Technologies, Inc. | Methods, compositions, and kits for generating nucleic acid products substantially free of template nucleic acid |
| US8409060B2 (en) | 2010-05-05 | 2013-04-02 | Gee Hoo Fitec Corp. | Exercise bike for rehabilitation |
| CN103827318B (zh) * | 2011-05-27 | 2018-05-08 | 生命技术公司 | 用于操作生物分子的方法 |
| US20130143774A1 (en) * | 2011-12-05 | 2013-06-06 | The Regents Of The University Of California | Methods and compositions for generating polynucleic acid fragments |
| EP3428290B1 (en) | 2012-07-26 | 2022-04-06 | Illumina, Inc. | Compositions and methods for the amplification of nucleic acids |
-
2014
- 2014-10-16 EP EP19167673.3A patent/EP3572527B1/en active Active
- 2014-10-16 EP EP21171323.5A patent/EP3875601A1/en active Pending
- 2014-10-16 DK DK19167673.3T patent/DK3572527T3/da active
- 2014-10-16 US US15/029,103 patent/US10294511B2/en active Active
- 2014-10-16 ES ES19167673T patent/ES2885191T3/es active Active
- 2014-10-16 DK DK14796335.9T patent/DK3058092T3/da active
- 2014-10-16 HU HUE14796335A patent/HUE045954T2/hu unknown
- 2014-10-16 EP EP14796335.9A patent/EP3058092B1/en active Active
- 2014-10-16 WO PCT/US2014/060942 patent/WO2015057985A1/en not_active Ceased
-
2019
- 2019-04-02 US US16/372,793 patent/US10683532B2/en active Active
- 2019-12-04 US US16/703,527 patent/US10988797B2/en active Active
-
2020
- 2020-10-12 US US17/068,062 patent/US11512340B2/en active Active
-
2022
- 2022-11-01 US US18/051,836 patent/US12227791B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3572527B1 (en) | 2021-05-26 |
| US20190292583A1 (en) | 2019-09-26 |
| HUE045954T2 (hu) | 2020-01-28 |
| US20200181687A1 (en) | 2020-06-11 |
| EP3058092B1 (en) | 2019-05-22 |
| US12227791B2 (en) | 2025-02-18 |
| US20210180113A1 (en) | 2021-06-17 |
| EP3875601A1 (en) | 2021-09-08 |
| US20160265027A1 (en) | 2016-09-15 |
| US10683532B2 (en) | 2020-06-16 |
| EP3572527A1 (en) | 2019-11-27 |
| EP3058092A1 (en) | 2016-08-24 |
| US10988797B2 (en) | 2021-04-27 |
| DK3572527T3 (da) | 2021-08-23 |
| US11512340B2 (en) | 2022-11-29 |
| US20230272453A1 (en) | 2023-08-31 |
| US10294511B2 (en) | 2019-05-21 |
| WO2015057985A1 (en) | 2015-04-23 |
| ES2885191T3 (es) | 2021-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3572527T3 (da) | Fremgangsmåder og præparater til fremstilling af nukleinsyrebiblioteker | |
| IL281817B (en) | Compositions and methods for immunotherapy | |
| DK3386550T3 (da) | Fremgangsmåder til fremstilling og anvendelse af guide nukleinsyrer | |
| DK2970896T3 (da) | Manipulerede levervæv, arrays deraf og fremgangsmåder til fremstilling heraf | |
| DK2912174T3 (da) | Fremgangsmåde og materialer til isolering af nukleinsyrematerialer | |
| DK3325669T3 (da) | Sammensætninger og fremgangsmåder til RNA-analyse | |
| LT3334841T (lt) | Nukleorūgščių tyrimo būdai | |
| DK3406633T3 (da) | Multispecifikke antistoffer, multispecifikke aktiverbare antistoffer og fremgangsmåder til anvendelse heraf | |
| DK3080274T3 (da) | Fremgangsmåder og sammensætninger til genom-manipulation | |
| DK3556869T3 (da) | Sammensætninger og fremgangsmåder til sekventering af polynukleotider | |
| DK3725807T3 (da) | Anti-cd47 antistoffer og fremgangsmåder til anvendelse deraf | |
| DK2951754T3 (da) | Fremgangsmåder, systemer og software til identifikation af biomolekyler med interagerende komponenter | |
| DK2968415T3 (da) | Cd123-specifik kimær antigenreceptor-omdirigerede t-celler og fremgangsmåder til anvendelse deraf | |
| DK3017286T3 (da) | Fremgangsmåde, kit og system til billeddannelse af en blodprøve | |
| DK3213065T3 (da) | System og fremgangsmåder til todimensionel rplc-sfc-kromatografi | |
| IL253341A0 (en) | Methods and compositions for combination immunotherapy | |
| DK3019200T3 (da) | Oligonukleotid-ligand-konjugater og fremgangsmåde til fremstiling deraf | |
| DK3456846T3 (da) | Systemer og fremgangsmåder til at stregkodemarkere nukleinsyre | |
| DK3079719T3 (da) | ANTI-SIGLEC-8-antistoffer og fremgangsmåder til anvendelse deraf | |
| DK2800565T3 (da) | Carbamatforbindelser og fremgangsmåder til fremstilling og anvendelse af samme | |
| DK3594348T3 (da) | Kort c/ebp-alpha til aktivering af rna-sammensætninger og anvendelsesfremgangsmåder | |
| DK3129912T3 (da) | Fremgangsmåde og system til sikring af data | |
| DK3030092T3 (da) | System og fremgangsmåde til fremstilling af et ekstruderet proteinprodukt | |
| IL285527A (en) | Compositions and methods for immunotherapy | |
| DK3083680T3 (da) | Humaniserede anti-Tau(pS422)-antistoffer og fremgangsmåder til anvendelse |