DK307384D0 - Ny plasminogen-aktivator og fremgangsmaade til fremstilling heraf samt thrombolytisk middel indeholdende samme - Google Patents

Ny plasminogen-aktivator og fremgangsmaade til fremstilling heraf samt thrombolytisk middel indeholdende samme

Info

Publication number
DK307384D0
DK307384D0 DK307384A DK307384A DK307384D0 DK 307384 D0 DK307384 D0 DK 307384D0 DK 307384 A DK307384 A DK 307384A DK 307384 A DK307384 A DK 307384A DK 307384 D0 DK307384 D0 DK 307384D0
Authority
DK
Denmark
Prior art keywords
preparing
plasminogen activator
agents containing
containing same
thrombolytic agents
Prior art date
Application number
DK307384A
Other languages
English (en)
Other versions
DK169686B1 (da
DK307384A (da
Inventor
Seishi Takahashi
Kazushi Morimoto
Yoshikazu Fujisawa
Fumiaki Ikeda
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57189067A external-priority patent/JPS5980613A/ja
Priority claimed from JP57189065A external-priority patent/JPH0637398B2/ja
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of DK307384D0 publication Critical patent/DK307384D0/da
Publication of DK307384A publication Critical patent/DK307384A/da
Application granted granted Critical
Publication of DK169686B1 publication Critical patent/DK169686B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK307384A 1982-10-29 1984-06-22 Fremgangsmåde til fremstilling af en plasminogenaktivator afledt fra humannyre DK169686B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP18906782 1982-10-29
JP18906582 1982-10-29
JP57189067A JPS5980613A (ja) 1982-10-29 1982-10-29 新規なプラスミノ−ゲン・アクチベ−タ及びその製造方法
JP57189065A JPH0637398B2 (ja) 1982-10-29 1982-10-29 血栓溶解剤
JP8300386 1983-10-27
PCT/JP1983/000386 WO1984001714A1 (fr) 1982-10-29 1983-10-27 Nouvel activateur de plasminogene, son procede de preparation et medicament thrombolytique le contenant

Publications (3)

Publication Number Publication Date
DK307384D0 true DK307384D0 (da) 1984-06-22
DK307384A DK307384A (da) 1984-06-22
DK169686B1 DK169686B1 (da) 1995-01-09

Family

ID=26505289

Family Applications (1)

Application Number Title Priority Date Filing Date
DK307384A DK169686B1 (da) 1982-10-29 1984-06-22 Fremgangsmåde til fremstilling af en plasminogenaktivator afledt fra humannyre

Country Status (12)

Country Link
EP (1) EP0124613B1 (da)
CA (1) CA1221029A (da)
CH (1) CH660742A5 (da)
DE (1) DE3390272C2 (da)
DK (1) DK169686B1 (da)
FI (1) FI80597C (da)
GB (1) GB2138824B (da)
IT (1) IT1169910B (da)
NL (1) NL191755C (da)
NO (1) NO166314C (da)
SE (1) SE8403375L (da)
WO (1) WO1984001714A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151996B1 (en) * 1984-01-30 1991-04-03 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a double-chain plasminogen activator
SE462893B (sv) * 1985-05-28 1990-09-17 Wellcome Found Vattenhaltig parenteral loesning av vaevnadsplasminogenaktivator och saett foer framstaellning av den
US4929444A (en) * 1985-05-28 1990-05-29 Burroughs Wellcome Co. Low pH pharmaceutical formulation containing t-PA
WO1988000615A1 (en) * 1986-07-16 1988-01-28 Celltech Limited Process for purifying a plasminogen activator
JPS6379591A (ja) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc tPAの精製方法
AU1668988A (en) * 1987-06-03 1988-12-08 Smithkline Beckman Corporation Purification of tpa
DE3726019A1 (de) * 1987-08-05 1989-02-16 Boehringer Mannheim Gmbh Verfahren zur abtrennung und reinigung von t-pa

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
JPS5913732A (ja) * 1982-07-16 1984-01-24 Mitsui Toatsu Chem Inc 血栓溶解剤

Also Published As

Publication number Publication date
EP0124613A1 (en) 1984-11-14
DK169686B1 (da) 1995-01-09
CA1221029A (en) 1987-04-28
FI842627L (fi) 1984-06-29
EP0124613B1 (en) 1992-12-30
WO1984001714A1 (fr) 1984-05-10
NO166314B (no) 1991-03-25
FI842627A0 (fi) 1984-06-29
EP0124613A4 (en) 1986-07-29
GB8414992D0 (en) 1984-07-18
NL8320346A (nl) 1984-09-03
FI80597B (fi) 1990-03-30
SE8403375D0 (sv) 1984-06-25
GB2138824A (en) 1984-10-31
CH660742A5 (de) 1987-06-15
FI80597C (fi) 1990-07-10
DE3390272T1 (de) 1984-11-29
SE8403375L (sv) 1984-06-25
NL191755B (nl) 1996-03-01
NO842468L (no) 1984-06-19
IT1169910B (it) 1987-06-03
IT8323533A0 (it) 1983-10-28
NL191755C (nl) 1996-07-02
DE3390272C2 (de) 1987-09-17
NO166314C (no) 1991-07-03
DK307384A (da) 1984-06-22
GB2138824B (en) 1986-12-31

Similar Documents

Publication Publication Date Title
DE3176876D1 (en) New plasminogen activator and pharmaceutical composition having thrombolytic activity
DE3484331D1 (de) Dekodierverfahren und vorrichtung dafuer.
MX9203520A (es) Inhibidores de proteasa de serina y metodos para aislar los mismos.
BR8207867A (pt) Cristal liquido encapsulado e metodo
DK164941C (da) Gaerhybridvektor, transformeret gaercelle samt fremgangsmaade til fremstilling af vaevsplasminogenaktivitor (tpa)
IT1177678B (it) Apparecchio e metodo per trasporto di rocche
DK45984D0 (da) Fremgangsmaade samt apparat til materialehaandtering
EP0112122A3 (en) Plasminogen activator
DK107784A (da) Fremgangsmaade og anlaeg til faremelding
DE3581226D1 (de) Verfahren und einrichtung zum schmelzen von metallbloecken.
IT1175411B (it) Sottogruppo statorico e metodo
DK267480A (da) Proteolytisk middel til proteinhydrolyse samt proteinhydrolyseproces
DK164319C (da) 4-hydroxy-2h-1-benzothiopyran-2-on-forbindelser og fremgangsmaade til fremstilling deraf samt rodenticidt middel indeholdende disse forbindelser
DK392284D0 (da) Lh-rh-antagonister og fremgangsmaade til fremstilling deraf samt farmaceutisk middel indeholdende disse
FI844105A7 (fi) Työstömenetelmä ja -laite.
DK307384D0 (da) Ny plasminogen-aktivator og fremgangsmaade til fremstilling heraf samt thrombolytisk middel indeholdende samme
DK206584A (da) Fremgangsmaade og middel til behandling af pruritus
KR860700103A (ko) 정교하게 전단하는 방법 및 그 장치
NO168184C (no) Fremgangsmaate for aa oeke utbyttet av plasminogen aktivator
KR860005884A (ko) 플라스미노겐 활성화제 전구체의 안정화 방법
DK381288A (da) Fremgangsmaade og anordning til maaling af vaevsplasminogenaktivator (t-pa) aktivitet
ZA774005B (en) Method of cutting diamonds and apparatus therefor
DK558683A (da) Thrombolytiske midler
DK551583A (da) Plasminogen-aktivator og fremgangsmaade til fremstilling heraf samt thrombolytisk middel indeholdende samme
DK397082A (da) Fremgangsmaade og middel til afretning af slibesten