DK3101141T3 - Fremgangsmåde til methyleringsanalyse - Google Patents
Fremgangsmåde til methyleringsanalyse Download PDFInfo
- Publication number
- DK3101141T3 DK3101141T3 DK16163841.6T DK16163841T DK3101141T3 DK 3101141 T3 DK3101141 T3 DK 3101141T3 DK 16163841 T DK16163841 T DK 16163841T DK 3101141 T3 DK3101141 T3 DK 3101141T3
- Authority
- DK
- Denmark
- Prior art keywords
- analyzing analysis
- analyzing
- analysis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07109907 | 2007-06-08 | ||
| EP07110409 | 2007-06-15 | ||
| EP07113516 | 2007-07-31 | ||
| EP07114659 | 2007-08-21 | ||
| EP07114863 | 2007-08-23 | ||
| EP08150552 | 2008-01-23 | ||
| EP08151442 | 2008-02-14 | ||
| EP12164321.7A EP2479289B1 (en) | 2007-06-08 | 2008-06-06 | Method for methylation analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3101141T3 true DK3101141T3 (da) | 2020-02-03 |
Family
ID=40094240
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16163841.6T DK3101141T3 (da) | 2007-06-08 | 2008-06-06 | Fremgangsmåde til methyleringsanalyse |
| DK12164321.7T DK2479289T3 (da) | 2007-06-08 | 2008-06-06 | Fremgangsmåde til methyleringsanalyse |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12164321.7T DK2479289T3 (da) | 2007-06-08 | 2008-06-06 | Fremgangsmåde til methyleringsanalyse |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8623599B2 (da) |
| EP (3) | EP3101141B1 (da) |
| CY (1) | CY1118259T1 (da) |
| DK (2) | DK3101141T3 (da) |
| ES (2) | ES2570828T3 (da) |
| HR (2) | HRP20160425T1 (da) |
| HU (1) | HUE028727T2 (da) |
| LT (1) | LT3101141T (da) |
| PL (1) | PL2479289T3 (da) |
| SI (2) | SI3101141T1 (da) |
| WO (1) | WO2008149237A2 (da) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7601497B2 (en) * | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| TWI417389B (zh) | 2008-10-27 | 2013-12-01 | Qiagen Gaithersburg Inc | 於自動平台上之快速結果雜交捕捉法 |
| AU2010242867B2 (en) * | 2009-05-01 | 2016-05-12 | Qiagen Gaithersburg, Inc. | A non-target amplification method for detection of RNA splice-forms in a sample |
| JP5826752B2 (ja) | 2009-09-14 | 2015-12-02 | キアジェン ゲイサーズバーグ インコーポレイテッド | 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法 |
| EP2480685B1 (en) | 2009-09-23 | 2013-08-28 | Koninklijke Philips Electronics N.V. | Method for monitoring the bisulfite-mediated conversion of dna |
| ES2615728T3 (es) * | 2010-01-29 | 2017-06-08 | Qiagen Gaithersburg, Inc. | Métodos y composiciones para una purificación y un análisis múltiple específico de secuencia de ácidos nucleicos |
| CA2787781A1 (en) | 2010-01-29 | 2011-08-04 | Qiagen Gaithersburg, Inc. | Method of determining and confirming the presence of an hpv in a sample |
| US9422593B2 (en) | 2010-05-19 | 2016-08-23 | Qiagen Gaithresburg, Inc | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| CA2799205A1 (en) | 2010-05-25 | 2011-12-01 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically-truncated probes |
| US9725754B2 (en) * | 2010-07-29 | 2017-08-08 | Sean F. Boyle | Generic sample preparation |
| US8916344B2 (en) | 2010-11-15 | 2014-12-23 | Exact Sciences Corporation | Methylation assay |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| AU2012220575B2 (en) | 2011-02-24 | 2017-01-12 | Qiagen Gaithersburg, Inc. | Materials and methods for detection of HPV nucleic acid |
| ES2675584T3 (es) | 2012-01-30 | 2018-07-11 | Exact Sciences Development Company, Llc | Modificación de ADN en perlas magnéticas |
| US9121061B2 (en) * | 2012-03-15 | 2015-09-01 | New England Biolabs, Inc. | Methods and compositions for discrimination between cytosine and modifications thereof and for methylome analysis |
| EP2746403A1 (de) | 2012-12-21 | 2014-06-25 | Life Science Inkubator GmbH & Co. KG | Verfahren zur Bestimmung des DNA-Methylierungsgrades |
| ES2859645T3 (es) | 2013-03-14 | 2021-10-04 | Mayo Found Medical Education & Res | Detección de neoplasia |
| CN105026580A (zh) * | 2013-03-15 | 2015-11-04 | 雅培分子公司 | 重亚硫酸盐转化的核苷酸序列的检测 |
| WO2015159293A2 (en) | 2014-04-14 | 2015-10-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | A method and kit for determining the tissue or cell origin of dna |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| ES2896058T3 (es) * | 2014-12-19 | 2022-02-23 | Epigenomics Ag | Métodos para detectar la metilación de CpG y para el diagnóstico del cáncer |
| WO2016160454A1 (en) | 2015-03-27 | 2016-10-06 | Exact Sciences Corporation | Detecting esophageal disorders |
| KR20250172724A (ko) | 2015-08-31 | 2025-12-09 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 위 신생물 검출 방법 |
| KR20250073555A (ko) | 2015-10-30 | 2025-05-27 | 이그잭트 사이언시즈 코포레이션 | 복합 증폭 검출 분석 및 혈장으로부터 dna의 분리 및 검출 방법 |
| US11021743B2 (en) * | 2015-11-27 | 2021-06-01 | Agency For Science, Technology And Research | Determination of nucleic acid methylation |
| CN105506133A (zh) * | 2016-01-15 | 2016-04-20 | 武汉艾米森生命科技有限公司 | 用于检测sept9基因甲基化的组合物、试剂盒及方法 |
| CN116064796A (zh) | 2016-05-05 | 2023-05-05 | 精密科学公司 | 通过分析甲基化dna来检测肺肿瘤 |
| JP7289264B2 (ja) | 2017-01-27 | 2023-06-09 | エグザクト サイエンシーズ コーポレーション | メチル化ｄｎａの分析による結腸腫瘍の検出 |
| CN107164524A (zh) * | 2017-06-27 | 2017-09-15 | 深圳市优圣康生物科技有限公司 | 用于基因甲基化检测的引物和探针、采样方法、试剂盒 |
| EP3652342A1 (en) * | 2017-07-13 | 2020-05-20 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Detecting tissue-specific dna |
| US11466323B2 (en) | 2017-07-13 | 2022-10-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Dual-probe digital droplet PCR strategy for specific detection of tissue-specific circulating DNA molecules |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| CN108048570A (zh) * | 2017-12-29 | 2018-05-18 | 韩林志 | 用于结直肠癌相关基因Septin9甲基化检测的引物对、试剂盒及方法 |
| CN110283913A (zh) * | 2019-07-21 | 2019-09-27 | 广州奥百阕谱生物科技有限公司 | Rassf1a基因甲基化状态检测试剂盒及其应用 |
| WO2025147442A1 (en) * | 2024-01-02 | 2025-07-10 | Grail, Inc. | Rapid bisulfite conversion and recovery of nucleic acid molecules |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3525072A1 (de) | 1985-07-13 | 1987-01-22 | Basf Ag | Verfahren zur herstellung von ueber o,o'-methylenether verknuepften phenolharzen und deren verwendung |
| DE3924052A1 (de) | 1989-07-21 | 1991-01-24 | Bayer Ag | N- (indol-6-yl)-heterocyclen |
| CA2062918A1 (en) | 1991-04-01 | 1992-10-02 | Richard A. Carpenter | Method for operating a networked computer system to minimize data conversion overhead |
| EP0609013A3 (en) | 1993-01-21 | 1995-11-29 | Matsushita Electric Industrial Co Ltd | Recording player. |
| US5786146A (en) | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| WO1998056952A1 (en) | 1997-06-09 | 1998-12-17 | University Of Southern California | A cancer diagnostic method based upon dna methylation differences |
| DE19754482A1 (de) | 1997-11-27 | 1999-07-01 | Epigenomics Gmbh | Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke |
| GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
| US6277607B1 (en) | 1999-05-24 | 2001-08-21 | Sanjay Tyagi | High specificity primers, amplification methods and kits |
| DE19957827C2 (de) | 1999-11-25 | 2003-06-12 | Epigenomics Ag | Verwendung eines Oligomer-Arrays mit PNA- und/oder DNA-Oligomeren auf einer Oberfläche |
| DE10010280B4 (de) | 2000-02-25 | 2006-08-10 | Epigenomics Ag | Verfahren zur Detektion von Cytosin-Methylierung in DNA Proben |
| DE10010281B4 (de) | 2000-02-25 | 2005-03-10 | Epigenomics Ag | Ligase/Polymerase-Verfahren zur Detektion von Cytosin-Methylierung in DNA Proben |
| DE10010282B4 (de) | 2000-02-25 | 2006-11-16 | Epigenomics Ag | Verfahren zur Detektion von Cytosin-Methylierung in DNA Proben |
| DE10029915B4 (de) | 2000-06-19 | 2005-06-16 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungen |
| US7214485B2 (en) | 2000-08-25 | 2007-05-08 | Lovelace Respiratory Research Institute | Nested methylation-specific polymerase chain reaction cancer detection method |
| DK1423528T3 (da) | 2000-09-01 | 2008-05-13 | Epigenomics Ag | Fremgangsmåde til bestemmelse af methyleringsgraden af bestemte cytosiner i genomisk DNA i sekvenskonteksten 5-CPG-3 |
| DE10112515B4 (de) | 2001-03-09 | 2004-02-12 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungsmustern mit hoher Sensitivität |
| US6927028B2 (en) | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
| DE10338308B4 (de) | 2003-08-15 | 2006-10-19 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungen in DNA |
| DE602004021192D1 (de) | 2003-10-09 | 2009-07-02 | Epigenomics Ag | Verbesserte bisulfitkonversion von dna |
| WO2006039563A2 (en) | 2004-09-30 | 2006-04-13 | Epigenomics Ag | Method for providing dna fragments derived from an archived sample |
| WO2007039101A1 (en) | 2005-09-30 | 2007-04-12 | Epigenomics Ag | Method for the quantification of nucleic acids, in particular bisulfite treated dna |
| EP1659186B1 (en) | 2004-10-11 | 2008-05-21 | Epigenomics AG | A method for the carry-over protection in DNA amplification systems targeting methylation analysis achieved by a modified pre-treatment of nucleic acids |
| WO2006088978A1 (en) | 2005-02-16 | 2006-08-24 | Epigenomics, Inc. | Method for determining the methylation pattern of a polynucleic acid |
| WO2006103111A2 (en) | 2005-04-01 | 2006-10-05 | Epigenomics Ag | Improved bisulfite conversion of dna |
| CA2606296C (en) | 2005-04-15 | 2019-05-21 | Epigenomics Ag | Methods and nucleic acids for analyses of cellular proliferative disorders |
| WO2006113770A1 (en) | 2005-04-15 | 2006-10-26 | Epigenomics Ag | A method for providing dna fragments derived from a remote sample |
-
2008
- 2008-06-06 DK DK16163841.6T patent/DK3101141T3/da active
- 2008-06-06 EP EP16163841.6A patent/EP3101141B1/en active Active
- 2008-06-06 WO PCT/IB2008/002118 patent/WO2008149237A2/en not_active Ceased
- 2008-06-06 EP EP12164321.7A patent/EP2479289B1/en active Active
- 2008-06-06 US US12/451,943 patent/US8623599B2/en not_active Expired - Fee Related
- 2008-06-06 SI SI200832109T patent/SI3101141T1/sl unknown
- 2008-06-06 ES ES12164321T patent/ES2570828T3/es active Active
- 2008-06-06 DK DK12164321.7T patent/DK2479289T3/da active
- 2008-06-06 SI SI200831602A patent/SI2479289T1/sl unknown
- 2008-06-06 HU HUE12164321A patent/HUE028727T2/en unknown
- 2008-06-06 PL PL12164321.7T patent/PL2479289T3/pl unknown
- 2008-06-06 EP EP08789067A patent/EP2152902A2/en not_active Withdrawn
- 2008-06-06 ES ES16163841T patent/ES2769841T3/es active Active
- 2008-06-06 LT LTEP16163841.6T patent/LT3101141T/lt unknown
-
2016
- 2016-04-21 HR HRP20160425TT patent/HRP20160425T1/hr unknown
- 2016-05-10 CY CY20161100391T patent/CY1118259T1/el unknown
-
2020
- 2020-01-16 HR HRP20200059TT patent/HRP20200059T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3101141A3 (en) | 2017-01-11 |
| EP2152902A2 (en) | 2010-02-17 |
| EP2479289A2 (en) | 2012-07-25 |
| LT3101141T (lt) | 2020-03-10 |
| EP3101141B1 (en) | 2019-10-16 |
| WO2008149237A2 (en) | 2008-12-11 |
| CY1118259T1 (el) | 2017-06-28 |
| US20110009277A1 (en) | 2011-01-13 |
| HUE028727T2 (en) | 2017-01-30 |
| ES2769841T3 (es) | 2020-06-29 |
| PL2479289T3 (pl) | 2016-10-31 |
| US8623599B2 (en) | 2014-01-07 |
| ES2570828T3 (es) | 2016-05-20 |
| HRP20200059T1 (hr) | 2020-04-03 |
| SI3101141T1 (sl) | 2020-03-31 |
| EP3101141A2 (en) | 2016-12-07 |
| SI2479289T1 (sl) | 2016-10-28 |
| DK2479289T3 (da) | 2016-05-02 |
| HRP20160425T1 (hr) | 2016-08-12 |
| EP2479289B1 (en) | 2016-04-06 |
| HK1172656A1 (en) | 2013-04-26 |
| WO2008149237A3 (en) | 2009-06-04 |
| EP2479289A3 (en) | 2013-06-19 |
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