DK31486A - Tricycliske forbindelser - Google Patents

Tricycliske forbindelser Download PDF

Info

Publication number: DK31486A
Authority: DK; Denmark
Prior art keywords: sup; hydrogen; lower alkyl; compounds; group
Prior art date: 1985-01-22

Application number

DK31486A

Other languages

English (en)

Other versions

DK31486D0 (da

Inventor

Niels-Erik Willman

Bengt Christer Hans Sjoegren

Lennart Gustav Nordh

Gustav Lennart Persson

Goeran Henry Sjoeholm

Original Assignee

Leo Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-22

Filing date

1986-01-21

Publication date

1986-07-23

1986-01-21 Application filed by Leo Ab filed Critical Leo Ab

1986-01-21 Publication of DK31486D0 publication Critical patent/DK31486D0/da

1986-07-23 Publication of DK31486A publication Critical patent/DK31486A/da

Links

150000001875 compounds Chemical class 0.000 title abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 5
GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 3
RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
125000003342 alkenyl group Chemical group 0.000 abstract 2
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
-1 nitro, hydroxy, cyano, carbamyl Chemical group 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000000278 alkyl amino alkyl group Chemical group 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000004103 aminoalkyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
150000007522 mineralic acids Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
150000007524 organic acids Chemical class 0.000 abstract 1
235000005985 organic acids Nutrition 0.000 abstract 1
ATYBXHSAIOKLMG-UHFFFAOYSA-N oxepin Chemical compound O1C=CC=CC=C1 ATYBXHSAIOKLMG-UHFFFAOYSA-N 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000005034 trifluormethylthio group Chemical group FC(S*)(F)F 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/12—[b,e]-condensed

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrane Compounds (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK31486A 1985-01-22 1986-01-21 Tricycliske forbindelser DK31486A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8500273A SE8500273D0 (sv)	1985-01-22	1985-01-22	Nya tricykliska foreningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder

Publications (2)

Publication Number	Publication Date
DK31486D0 DK31486D0 (da)	1986-01-21
DK31486A true DK31486A (da)	1986-07-23

Family

ID=20358842

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK31486A DK31486A (da)	1985-01-22	1986-01-21	Tricycliske forbindelser

Country Status (12)

Country	Link
US (1)	US4645758A (da)
EP (1)	EP0189078B1 (da)
JP (1)	JPH0798817B2 (da)
AT (1)	ATE44280T1 (da)
AU (1)	AU587597B2 (da)
CA (1)	CA1309409C (da)
DE (1)	DE3664136D1 (da)
DK (1)	DK31486A (da)
FI (1)	FI860199A7 (da)
IE (1)	IE59600B1 (da)
NO (1)	NO855373L (da)
SE (1)	SE8500273D0 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0560831B1 (da) *	1986-06-17	1993-09-03	Dainippon Pharmaceutical Co
GB9318935D0 (en) *	1992-10-20	1993-10-27	Zeneca Ltd	Heterocyclic derivatives
US5340826A (en) *	1993-02-04	1994-08-23	Pfizer Inc.	Pharmaceutical agents for treatment of urinary incontinence
US5574173A (en) *	1993-12-06	1996-11-12	Schering Corporation	Tricyclic derivatives, compositions and methods of use
JP3348230B2 (ja)	1995-03-03	2002-11-20	アルゴスファーマシューティカルコーポレーション	尿失禁の治療用のデキシトルメトルファン又はデキシトルオルファンの使用
ES2259795T3 (es) *	1995-06-07	2006-10-16	Nippon Shinyaku Company, Limited	Derivados de pirrol y composicion medicinal.
US6323206B1 (en)	1996-07-12	2001-11-27	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
BR9808552A (pt) *	1997-04-15	2000-05-23	Kyowa Hakko Kogyo Kk	Composto tricìclico ou um sal farmaceuticamente aceitável do mesmo, e, composição farmacêutica
US6509346B2 (en)	1998-01-21	2003-01-21	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
DK1049700T3 (da)	1998-01-21	2006-02-20	Millennium Pharm Inc	Kemokinreceptorantagonister og fremgangsmåder til anvendelse deraf
US6613905B1 (en)	1998-01-21	2003-09-02	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
US7271176B2 (en) *	1998-09-04	2007-09-18	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use thereof
US7541365B2 (en)	2001-11-21	2009-06-02	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
US7378408B2 (en) *	2001-11-30	2008-05-27	Pfizer Inc.	Methods of treatment and formulations of cephalosporin
TWI291467B (en) *	2002-11-13	2007-12-21	Millennium Pharm Inc	CCR1 antagonists and methods of use therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL279409A (da) *	1961-06-08
NL300844A (da) *	1962-11-24
NL130988C (da) *	1966-07-21		Boehringer Mannheim Gmbh
US3876659A (en) *	1970-09-18	1975-04-08	Sandoz Ag	Spiro tricyclic isoindolines
FR2512024A1 (fr) *	1981-08-27	1983-03-04	Adir	Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant
JPS6147466A (ja) *	1984-08-10	1986-03-07	Dainippon Pharmaceut Co Ltd	アミン誘導体

1985
- 1985-01-22 SE SE8500273A patent/SE8500273D0/xx unknown
- 1985-12-30 IE IE332585A patent/IE59600B1/en not_active IP Right Cessation
- 1985-12-30 NO NO855373A patent/NO855373L/no unknown
1986
- 1986-01-10 AU AU52171/86A patent/AU587597B2/en not_active Ceased
- 1986-01-11 DE DE8686100324T patent/DE3664136D1/de not_active Expired
- 1986-01-11 AT AT86100324T patent/ATE44280T1/de not_active IP Right Cessation
- 1986-01-11 EP EP86100324A patent/EP0189078B1/en not_active Expired
- 1986-01-16 FI FI860199A patent/FI860199A7/fi not_active Application Discontinuation
- 1986-01-17 US US06/820,428 patent/US4645758A/en not_active Expired - Fee Related
- 1986-01-21 CA CA000500044A patent/CA1309409C/en not_active Expired - Fee Related
- 1986-01-21 JP JP61010959A patent/JPH0798817B2/ja not_active Expired - Lifetime
- 1986-01-21 DK DK31486A patent/DK31486A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
DK31486D0 (da)	1986-01-21
JPH0798817B2 (ja)	1995-10-25
US4645758A (en)	1987-02-24
FI860199A7 (fi)	1986-07-23
JPS61172871A (ja)	1986-08-04
IE853325L (en)	1986-07-22
SE8500273D0 (sv)	1985-01-22
AU5217186A (en)	1986-07-31
AU587597B2 (en)	1989-08-24
NO855373L (no)	1986-07-23
CA1309409C (en)	1992-10-27
EP0189078A1 (en)	1986-07-30
EP0189078B1 (en)	1989-06-28
IE59600B1 (en)	1994-03-09
DE3664136D1 (en)	1989-08-03
ATE44280T1 (de)	1989-07-15
FI860199A0 (fi)	1986-01-16

Legal Events

Date	Code	Title	Description
1992-10-12	AHS	Application shelved for other reasons than non-payment

Publication	Publication Date	Title
AU587597B2 (en)	1989-08-24	Tricyclic compounds, compositions containing such compounds, processes for their preparation and method of treatment therewith
YU115588A (en)	1988-10-31	Process for obtaining derivatives of pyrimidanone as calcium independent camp inhibitors of phosphodiestheraze
EP1020445A4 (en)	2001-06-20	CONDENSED PYRIDE DERIVATIVES
IL103944A0 (en)	1993-05-13	Piperazine derivatives,their preparation and pharmaceutical compositions containing them
HUP9900790A2 (hu)	1999-06-28	Imidazo-kinazolin-származékok
DK0656353T3 (da)	1999-02-01	Aminoquinolinderivater med en virkning mod malariafremkaldere
NZ232283A (en)	1991-08-27	Substituted imidazo(1,2-b)pyridazine derivatives; pharmaceutical compositions and preparatory processes
IL110979A0 (en)	1994-11-28	Substituted 17beta -anilide-4-aza-5alpha -androstan 3-one their preparation and pharmaceutical com containing them
GB8427125D0 (en)	1984-12-05	Organic compounds
IE822310L (en)	1983-03-24	Triazoloquinazolone derivatives
AU572747B2 (en)	1988-05-12	Aryloxy-n-(aminoalkyl)-1-pyrrolide and piperidine carboxamides and carbothiomides having antiarrythmic activity
AU1491092A (en)	1992-10-22	3-aryl oxazolidinone derivatives, a method of preparing them and therapeutic use thereof
AU657423B2 (en)	1995-03-09	Novel piperidine derivatives and process for preparation thereof
KR890002148A (ko)	1989-04-08	융합된 방향족 테트라하이드로 아제피논(및 티온)
ES2072193A1 (es)	1995-07-01	Nuevos derivados del1-fenilmetil bencimidazol piperacinas.
PH23845A (en)	1989-11-23	Tricyclic pyridazopyridine derivatives pharmaceutical composition containing same and method of use thereof
NO165593C (no)	1991-03-06	Analogifremgangsmaate ved fremstilling av nye tetracykliske indolderivater.
DE69018352D1 (de)	1995-05-11	N-hydroxy-dibenz[b,e]oxepin-alkylamine und -alkanoische Säureamide, verwandte heterocyclische Analoge, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Medikamenten.
DE3067580D1 (en)	1984-05-24	Substituted 4-amino-2,6-diaryl-tetrahydrothiopyranes, their acid-addition salts, processes for their preparation and pharmaceutical compositions
ES2040629A1 (es)	1993-10-16	Procedimiento de obtencion de derivados triciclicos de la benzotiazepina farmacologicamente activos.
PH18574A (en)	1985-08-12	Substituted 11-oxo-11h-pyrido 2,i-h -quinazoline derivatives,pharmaceutical compositions containing them and method of use thereof
PT83307A (en)	1986-10-01	Spirobenzofuran-2 (3h),1'-cycloheptanes a process and interme diates for their preparation and their use as medicaments
IE44349L (en)	1977-01-10	DERIVATIVES OF 4H-THIENO [3,2-b] [1] BENZAZEPINES
MX9710378A (es)	1998-07-31	Derivados de 4-finilaminotiazol, su proceso de preparacion y las composiciones farmaceuticas que los contienen.