DK316485A - Anvendelse af ibogain til fremstilling af et medikament til behandling af det narkotiske misbrugssyndrom - Google Patents

Anvendelse af ibogain til fremstilling af et medikament til behandling af det narkotiske misbrugssyndrom Download PDF

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Publication number
DK316485A
DK316485A DK316485A DK316485A DK316485A DK 316485 A DK316485 A DK 316485A DK 316485 A DK316485 A DK 316485A DK 316485 A DK316485 A DK 316485A DK 316485 A DK316485 A DK 316485A
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DK
Denmark
Prior art keywords
ibogain
treat
medicine
prepare
narcotic abuse
Prior art date
Application number
DK316485A
Other languages
English (en)
Other versions
DK156376B (da
DK156376C (da
DK316485D0 (da
Inventor
Howard S Lotsof
Original Assignee
Howard S Lotsof
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Howard S Lotsof filed Critical Howard S Lotsof
Publication of DK316485D0 publication Critical patent/DK316485D0/da
Publication of DK316485A publication Critical patent/DK316485A/da
Publication of DK156376B publication Critical patent/DK156376B/da
Application granted granted Critical
Publication of DK156376C publication Critical patent/DK156376C/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
DK316485A 1983-11-18 1985-07-11 Anvendelse af ibogain til fremstilling af et laegemiddel til behandling af narkotikamisbrug DK156376C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/553,138 US4499096A (en) 1983-11-18 1983-11-18 Rapid method for interrupting the narcotic addiction syndrome
US55313883 1983-11-18
PCT/US1984/001851 WO1985002115A1 (en) 1983-11-18 1984-11-13 A rapid method for interrupting the narcotic addiction syndrome
US8401851 1984-11-13

Publications (4)

Publication Number Publication Date
DK316485D0 DK316485D0 (da) 1985-07-11
DK316485A true DK316485A (da) 1985-07-11
DK156376B DK156376B (da) 1989-08-14
DK156376C DK156376C (da) 1990-01-02

Family

ID=24208273

Family Applications (1)

Application Number Title Priority Date Filing Date
DK316485A DK156376C (da) 1983-11-18 1985-07-11 Anvendelse af ibogain til fremstilling af et laegemiddel til behandling af narkotikamisbrug

Country Status (11)

Country Link
US (1) US4499096A (da)
EP (1) EP0163697B1 (da)
AU (1) AU576538B2 (da)
CA (1) CA1237986A (da)
DE (1) DE3482305D1 (da)
DK (1) DK156376C (da)
IE (1) IE58567B1 (da)
IL (1) IL73585A (da)
IT (1) IT1178249B (da)
NO (1) NO844573L (da)
WO (1) WO1985002115A1 (da)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4587243A (en) * 1985-07-15 1986-05-06 Lotsof Howard S Rapid method for interrupting the cocaine and amphetamine abuse syndrome
US4948803A (en) * 1986-11-21 1990-08-14 Glaxo Group Limited Medicaments for treatment on prevention of withdrawal syndrome
GB8627909D0 (en) * 1986-11-21 1986-12-31 Glaxo Group Ltd Medicaments
US4857523A (en) * 1988-07-18 1989-08-15 Nda International, Inc. Rapid method for attenuating the alcohol dependency syndrome
US5629307A (en) * 1989-10-20 1997-05-13 Olney; John W. Use of ibogaine in reducing excitotoxic brain damage
US5152994A (en) * 1990-05-31 1992-10-06 Lotsof Howard S Rapid method for interrupting or attenuating poly-drug dependency syndromes
ATE324897T1 (de) * 1994-07-25 2006-06-15 Nda Int Inc Verwendung von noribogain derivaten zur behandlung von chemischer abhängigkeit bei säugern
WO1997005869A1 (en) * 1995-08-08 1997-02-20 Albany Medical College Ibogamine congeners
US5616575A (en) * 1995-12-04 1997-04-01 Regents Of The University Of Minnesota Bioactive tricyclic ibogaine analogs
ATE265213T1 (de) * 1997-09-04 2004-05-15 Novoneuron Inc Noribogain zur behandlung von schmerzen und drogenabhängigkeit
US7220737B1 (en) 1997-09-04 2007-05-22 Novoneuron, Inc Noribogaine in the treatment of pain and drug addiction
US20030199439A1 (en) * 2002-04-22 2003-10-23 Simon David Lew Compositions of alpha3beta4 receptor antagonists and opioid agonist analgesics
US20030199496A1 (en) * 2002-04-22 2003-10-23 Simon David Lew Pharmaceutical compositions containing alpha3beta4 nicotinic receptor antagonists and methods of their use
US7157102B1 (en) 2002-05-31 2007-01-02 Biotek, Inc. Multi-layered microcapsules and method of preparing same
US7041320B1 (en) 2002-05-31 2006-05-09 Biotek, Inc. High drug loaded injectable microparticle compositions and methods of treating opioid drug dependence
US20040266659A1 (en) * 2003-06-27 2004-12-30 Stephen LaBerge Substances that enhance recall and lucidity during dreaming
US20050251442A1 (en) * 2004-05-07 2005-11-10 Joseph Ficalora Consumer incentive system and business method
US8267851B1 (en) 2009-06-16 2012-09-18 James M Kroll Method and apparatus for electrically generating signal for inducing lucid dreaming
US8362007B1 (en) 2010-05-11 2013-01-29 Demerx, Inc. Substituted noribogaine
US9394294B2 (en) 2010-05-11 2016-07-19 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8765737B1 (en) 2010-05-11 2014-07-01 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8802832B2 (en) 2010-06-22 2014-08-12 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US8741891B1 (en) 2010-06-22 2014-06-03 Demerx, Inc. N-substituted noribogaine prodrugs
US8637648B1 (en) 2010-06-22 2014-01-28 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US9586954B2 (en) 2010-06-22 2017-03-07 Demerx, Inc. N-substituted noribogaine prodrugs
CA2806232A1 (en) 2010-07-23 2012-01-26 Demerx, Inc. Noribogaine compositions
EP2481740B1 (en) 2011-01-26 2015-11-04 DemeRx, Inc. Methods and compositions for preparing noribogaine from voacangine
US9617274B1 (en) 2011-08-26 2017-04-11 Demerx, Inc. Synthetic noribogaine
CA2855994A1 (en) 2011-12-09 2013-06-13 Demerx, Inc. Phosphate esters of noribogaine
US20130178618A1 (en) 2012-01-10 2013-07-11 William Allen Boulanger Novel pharmaceutical intermediates and methods for preparing the same
CA2858820C (en) 2012-01-25 2021-08-17 Demerx, Inc. Synthetic voacangine
US9150584B2 (en) 2012-01-25 2015-10-06 Demerx, Inc. Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
CA2896133A1 (en) 2012-12-20 2014-06-26 Demerx, Inc. Substituted noribogaine
US8940728B2 (en) 2012-12-20 2015-01-27 Demerx, Inc. Substituted noribogaine
US9045481B2 (en) 2012-12-20 2015-06-02 Demerx, Inc. Substituted noribogaine
US9561233B2 (en) 2014-03-13 2017-02-07 Demerx, Inc. Use of ibogaine for the treatment of pain
WO2015195673A2 (en) 2014-06-18 2015-12-23 Demerx, Inc. Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them
US9592239B2 (en) 2014-09-12 2017-03-14 Demerx, Inc. Methods and compositions for ibogaine treatment of impulse control disorder, anxiety-related disorders, violence and/or anger, or regulating food intake
WO2016126272A1 (en) * 2015-02-04 2016-08-11 Robert Rand Rapid method of reducing motor and non-motor symptoms of parkinson's disease
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US12377112B2 (en) 2019-04-17 2025-08-05 Compass Pathfinder Limited Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
US12564597B2 (en) 2020-03-05 2026-03-03 The Trustees Of Columbia University In The Of New York Ibogaine analogs as therapeutics for neurological and psychiatric disorders
IL298323B2 (en) 2020-05-20 2023-10-01 Univ Illinois A method for treating lysosomal storage disease using histatin peptides
CA3208525A1 (en) * 2021-02-17 2022-08-25 Dalibor Sames Oxa-ibogaine analogues for treatment of substance use disorders
KR20250053869A (ko) 2022-08-26 2025-04-22 더 존스 홉킨스 유니버시티 환각제 치료제의 표적 전달을 위한 덴드리머 조성물
WO2024059713A2 (en) * 2022-09-14 2024-03-21 The Board Of Trustees Of The Leland Stanford Junior University Compositions of iboga alkaloids and methods of treatment
US12116372B1 (en) 2023-12-14 2024-10-15 William Allen Boulanger Process for preparing methyl 3-bromo-2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propanoate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2877229A (en) * 1959-03-10 Process for the manufacture of indoles

Also Published As

Publication number Publication date
IE58567B1 (en) 1993-10-06
EP0163697A1 (en) 1985-12-11
IT8449184A0 (it) 1984-11-19
DK156376B (da) 1989-08-14
IL73585A0 (en) 1985-02-28
IL73585A (en) 1990-04-29
EP0163697A4 (en) 1986-04-15
DK156376C (da) 1990-01-02
EP0163697B1 (en) 1990-05-23
US4499096A (en) 1985-02-12
IT8449184A1 (it) 1986-05-19
CA1237986A (en) 1988-06-14
NO844573L (no) 1985-05-20
WO1985002115A1 (en) 1985-05-23
AU3674484A (en) 1985-06-03
IE842932L (en) 1985-05-18
IT1178249B (it) 1987-09-09
DK316485D0 (da) 1985-07-11
DE3482305D1 (de) 1990-06-28
AU576538B2 (en) 1988-09-01

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