DK3207481T3 - Reduktion af fejl ved forudsigelse af genetiske slægtskab - Google Patents

Reduktion af fejl ved forudsigelse af genetiske slægtskab Download PDF

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Publication number
DK3207481T3
DK3207481T3 DK15850218.7T DK15850218T DK3207481T3 DK 3207481 T3 DK3207481 T3 DK 3207481T3 DK 15850218 T DK15850218 T DK 15850218T DK 3207481 T3 DK3207481 T3 DK 3207481T3
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Denmark
Prior art keywords
reducing errors
genetic relationships
predicting genetic
predicting
relationships
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Application number
DK15850218.7T
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English (en)
Inventor
Mathew J Barber
Yong Wang
Keith D Noto
Kenneth G Chahine
Catherine Ann Ball
Original Assignee
Ancestry Com Dna Llc
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Publication of DK3207481T3 publication Critical patent/DK3207481T3/da

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N5/00—Computing arrangements using knowledge-based models
    • G06N5/04—Inference or reasoning models
    • G06N5/048—Fuzzy inferencing
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N7/00—Computing arrangements based on specific mathematical models
    • G06N7/01—Probabilistic graphical models, e.g. probabilistic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B10/00—ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Evolutionary Biology (AREA)
  • Genetics & Genomics (AREA)
  • Software Systems (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Evolutionary Computation (AREA)
  • Data Mining & Analysis (AREA)
  • Artificial Intelligence (AREA)
  • Physiology (AREA)
  • General Physics & Mathematics (AREA)
  • Mathematical Physics (AREA)
  • Computing Systems (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioethics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Databases & Information Systems (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Ecology (AREA)
  • Fuzzy Systems (AREA)
  • Automation & Control Theory (AREA)
  • Computational Linguistics (AREA)
  • Mathematical Analysis (AREA)
  • Probability & Statistics with Applications (AREA)
  • Algebra (AREA)
DK15850218.7T 2014-10-14 2015-10-14 Reduktion af fejl ved forudsigelse af genetiske slægtskab DK3207481T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462063849P 2014-10-14 2014-10-14
PCT/US2015/055579 WO2016061260A1 (en) 2014-10-14 2015-10-14 Reducing error in predicted genetic relationships

Publications (1)

Publication Number Publication Date
DK3207481T3 true DK3207481T3 (da) 2020-02-03

Family

ID=55747284

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15850218.7T DK3207481T3 (da) 2014-10-14 2015-10-14 Reduktion af fejl ved forudsigelse af genetiske slægtskab

Country Status (9)

Country Link
US (2) US10720229B2 (da)
EP (2) EP3207481B1 (da)
AU (1) AU2015332507B2 (da)
CA (1) CA2964780C (da)
DK (1) DK3207481T3 (da)
ES (1) ES2762942T3 (da)
MX (1) MX2017004989A (da)
PL (1) PL3207481T3 (da)
WO (1) WO2016061260A1 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10275569B2 (en) 2007-10-15 2019-04-30 22andMe, Inc. Family inheritance
US9336177B2 (en) 2007-10-15 2016-05-10 23Andme, Inc. Genome sharing
EP2370929A4 (en) 2008-12-31 2016-11-23 23Andme Inc SEARCH FOR RELATED IN A DATABASE
US8990250B1 (en) 2011-10-11 2015-03-24 23Andme, Inc. Cohort selection with privacy protection
US10437858B2 (en) 2011-11-23 2019-10-08 23Andme, Inc. Database and data processing system for use with a network-based personal genetics services platform
US10025877B2 (en) 2012-06-06 2018-07-17 23Andme, Inc. Determining family connections of individuals in a database
US9213947B1 (en) 2012-11-08 2015-12-15 23Andme, Inc. Scalable pipeline for local ancestry inference
US9213944B1 (en) 2012-11-08 2015-12-15 23Andme, Inc. Trio-based phasing using a dynamic Bayesian network
CA2964780C (en) * 2014-10-14 2023-03-21 Ancestry.Com Dna, Llc Reducing error in predicted genetic relationships
MX2017004980A (es) 2014-10-17 2017-12-07 Ancestry Com Dna Llc Genomas humanos ancestrales.
US10867705B2 (en) 2014-11-06 2020-12-15 Ancestryhealth.Com, Llc Predicting health outcomes
EP3323067B1 (en) * 2015-07-13 2022-07-06 Ancestry.com DNA, LLC Local genetic ethnicity determination system
CA3033521A1 (en) * 2016-08-10 2018-02-15 New York Genome Center, Inc. Ultra-low coverage genome sequencing and uses thereof
CA3109275A1 (en) 2018-08-17 2020-02-20 Ancestry.Com Dna, Llc Prediction of phenotypes using recommender systems
EP3874510A4 (en) 2018-10-31 2022-08-03 Ancestry.com DNA, LLC ESTIMATION OF PHENOTYPES USING DNA, PEDIGREE AND HISTORICAL DATA
CA3147888A1 (en) 2019-07-19 2021-01-28 23Andme, Inc. Phase-aware determination of identity-by-descent dna segments
AU2020326389B2 (en) * 2019-08-02 2023-10-05 Ancestry.Com Dna, Llc Clustering of matched segments to determine linkage of dataset in a database
US12050629B1 (en) 2019-08-02 2024-07-30 Ancestry.Com Dna, Llc Determining data inheritance of data segments
WO2021051018A1 (en) 2019-09-13 2021-03-18 23Andme, Inc. Methods and systems for determining and displaying pedigrees
JP2023501006A (ja) * 2019-11-18 2023-01-17 エンバーク ヴェテリナリー,インコーポレーテッド 祖先血縁を決定するための方法およびシステム
US11817176B2 (en) 2020-08-13 2023-11-14 23Andme, Inc. Ancestry composition determination
WO2022076909A1 (en) 2020-10-09 2022-04-14 23Andme, Inc. Formatting and storage of genetic markers
EP4341825A1 (en) 2021-05-20 2024-03-27 Ancestry.com Operations Inc. Domain knowledge guided selection of nodes for addition to data trees
WO2023281450A1 (en) 2021-07-09 2023-01-12 Ancestry.Com Operations Inc. Handwriting recognition pipelines for genealogical records
US20250032199A1 (en) 2022-02-10 2025-01-30 Digital Surgery Systems, Inc. Microphone directionality control based on surgeon's command
US20230281310A1 (en) * 2022-03-01 2023-09-07 Meta Plataforms, Inc. Systems and methods of uncertainty-aware self-supervised-learning for malware and threat detection
WO2023175516A1 (en) 2022-03-15 2023-09-21 Ancestry.Com Operations Inc. Machine-learning based automated document integration into genealogical trees
CA3256221A1 (en) 2022-04-13 2023-10-19 Ancestry.Com Dna, Llc Accelerated Hidden Markov Models for Genotype Analysis
US12461970B2 (en) 2022-08-19 2025-11-04 Ancestry.Com Dna, Llc Catalog-based data inheritance determination
WO2025049155A1 (en) 2023-08-25 2025-03-06 Ancestry.Com Dna, Llc Determining data inheritance of genomic data segments
US12639342B2 (en) 2023-10-24 2026-05-26 Ancestry.Com Dna, Llc Systems and methods for determining data-origin links between named entities
US20260017284A1 (en) 2024-07-09 2026-01-15 Ancestry.Com Dna, Llc Determining labels of inheritance datasets using simulated data instances

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2370929A4 (en) * 2008-12-31 2016-11-23 23Andme Inc SEARCH FOR RELATED IN A DATABASE
WO2011139797A2 (en) 2010-04-27 2011-11-10 Spiral Genetics Inc. Method and system for analysis and error correction of biological sequences and inference of relationship for multiple samples
WO2012099890A1 (en) * 2011-01-18 2012-07-26 University Of Utah Research Foundation Estimation of recent shared ancestry
AU2013312355A1 (en) * 2012-09-06 2014-09-18 Ancestry.Com Dna, Llc Using haplotypes to infer ancestral origins for recently admixed individuals
WO2014145280A1 (en) 2013-03-15 2014-09-18 Ancestry.Com Dna, Llc Family networks
CA2964780C (en) * 2014-10-14 2023-03-21 Ancestry.Com Dna, Llc Reducing error in predicted genetic relationships
US20170213127A1 (en) * 2016-01-24 2017-07-27 Matthew Charles Duncan Method and System for Discovering Ancestors using Genomic and Genealogic Data
CA3033521A1 (en) * 2016-08-10 2018-02-15 New York Genome Center, Inc. Ultra-low coverage genome sequencing and uses thereof
CN117746978A (zh) * 2017-09-07 2024-03-22 瑞泽恩制药公司 用于利用基因组数据分析中的亲缘关系的系统和方法

Also Published As

Publication number Publication date
CA2964780A1 (en) 2016-04-21
WO2016061260A1 (en) 2016-04-21
AU2015332507B2 (en) 2021-09-02
EP3621080B1 (en) 2023-09-06
EP3621080A1 (en) 2020-03-11
ES2762942T3 (es) 2020-05-26
AU2015332507A1 (en) 2017-06-01
EP3207481A4 (en) 2018-04-04
EP3207481A1 (en) 2017-08-23
EP3207481B1 (en) 2019-12-04
CA2964780C (en) 2023-03-21
US20170220738A1 (en) 2017-08-03
MX2017004989A (es) 2017-11-13
NZ731808A (en) 2021-10-29
PL3207481T3 (pl) 2020-05-18
US20200286591A1 (en) 2020-09-10
US10720229B2 (en) 2020-07-21

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