DK3209773T3 - Prolintolerante tripeptidylpeptidaser og anvendelser deraf - Google Patents

Prolintolerante tripeptidylpeptidaser og anvendelser deraf Download PDF

Info

Publication number
DK3209773T3
DK3209773T3 DK15793724.4T DK15793724T DK3209773T3 DK 3209773 T3 DK3209773 T3 DK 3209773T3 DK 15793724 T DK15793724 T DK 15793724T DK 3209773 T3 DK3209773 T3 DK 3209773T3
Authority
DK
Denmark
Prior art keywords
prolintolerant
tripeptidylpeptidases
applications
prolintolerant tripeptidylpeptidases
Prior art date
Application number
DK15793724.4T
Other languages
English (en)
Inventor
Ernst Meinjohanns
Andrei Miasnikov
Maria Ma
Svend Haaning
Steffen Yde Bak
Karsten Matthias Kragh
Peter Edvard Degn
Thomas Eisele
Original Assignee
Dupont Nutrition Biosci Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupont Nutrition Biosci Aps filed Critical Dupont Nutrition Biosci Aps
Application granted granted Critical
Publication of DK3209773T3 publication Critical patent/DK3209773T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485—Exopeptidases (3.4.11-3.4.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C12Y304/14009—Tripeptidyl-peptidase I (3.4.14.9)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Birds (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Fodder In General (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
  • General Preparation And Processing Of Foods (AREA)
DK15793724.4T 2014-10-24 2015-10-23 Prolintolerante tripeptidylpeptidaser og anvendelser deraf DK3209773T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462068243P 2014-10-24 2014-10-24
US201462068282P 2014-10-24 2014-10-24
US201462068264P 2014-10-24 2014-10-24
US201462093301P 2014-12-17 2014-12-17
PCT/EP2015/074600 WO2016062855A1 (en) 2014-10-24 2015-10-23 Proline tolerant tripeptidyl peptidases and uses thereof

Publications (1)

Publication Number Publication Date
DK3209773T3 true DK3209773T3 (da) 2020-06-15

Family

ID=54540018

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15793724.4T DK3209773T3 (da) 2014-10-24 2015-10-23 Prolintolerante tripeptidylpeptidaser og anvendelser deraf
DK15794483.6T DK3209774T3 (da) 2014-10-24 2015-10-23 Anvendelse af prolintolerante tripeptidylpeptidaser i foderadditivsammensætninger

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK15794483.6T DK3209774T3 (da) 2014-10-24 2015-10-23 Anvendelse af prolintolerante tripeptidylpeptidaser i foderadditivsammensætninger

Country Status (13)

Country Link
US (4) US20180295858A1 (da)
EP (2) EP3209774B1 (da)
JP (1) JP6878275B2 (da)
CN (2) CN107105707B (da)
AU (2) AU2015334890B2 (da)
BR (2) BR112017008304A2 (da)
CA (2) CA2965438A1 (da)
DK (2) DK3209773T3 (da)
ES (1) ES2791891T3 (da)
MX (2) MX381014B (da)
RU (1) RU2741080C2 (da)
WO (2) WO2016062857A1 (da)
ZA (1) ZA201702889B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190230958A1 (en) * 2016-06-23 2019-08-01 Ew Nutrition Gmbh Feed composition comprising an acid protease
WO2018005229A1 (en) 2016-06-30 2018-01-04 Dupont Nutrition Biosciences Aps In feed assay of microbial proteases using peptide substrates
HUE069487T2 (hu) 2016-12-23 2025-03-28 Heidelberg Pharma Res Gmbh Amanitin-antitest konjugátumok
WO2018224035A1 (en) * 2017-06-09 2018-12-13 Novozymes A/S Polypeptide, use and method for hydrolysing protein
CN107467370A (zh) * 2017-10-13 2017-12-15 无锡正大生物股份有限公司 一种饲料用功能性诱食剂及其制备方法
US10980253B2 (en) * 2017-12-28 2021-04-20 Global Earth Solutions, Llc Composition, system and method for pellet or flake production
WO2020077106A1 (en) * 2018-10-11 2020-04-16 Imbria Pharmaceuticals, Inc. Compositions and methods for treating and preventing leber's hereditary optic neuropathy
AU2020216682B2 (en) * 2019-01-28 2022-08-04 Nutreco Ip Assets B.V. Feed for aquatic species with a stable soft and elastic texture
CN110551790B (zh) * 2019-07-29 2021-09-14 浙江大学 一种乳源活性肽的制备方法及应用
CN114630584A (zh) 2019-11-07 2022-06-14 纽崔西亚公司 具有致耐受性肽的深度乳清蛋白水解产物
US20240002457A1 (en) * 2020-11-16 2024-01-04 Arizona Board Of Regents On Behalf Of The University Of Arizona Vibrio toxin binding proteins in shrimp and uses thereof
CN120957611A (zh) * 2023-03-27 2025-11-14 帝斯曼知识产权资产管理有限公司 酶组合物和啤酒酿造方法
EP4437856A1 (en) * 2023-03-31 2024-10-02 DSM IP Assets B.V. Novel enzyme composition and novel beer brewing process
LU504450B1 (en) * 2023-06-07 2024-12-09 Traceless Mat Gmbh Process for producing an animal feed
CN117491351B (zh) * 2023-12-27 2024-04-05 中国农业科学院北京畜牧兽医研究所 一种肉鸡饲料有效磷的仿生消化测定试剂盒和测定方法
CN118931885A (zh) * 2024-06-17 2024-11-12 深极美泰(山东)生物科技有限公司 一种金属蛋白酶Aquinlysin及其制备鳀鱼粉活性肽的应用

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DE3546807C2 (da) 1985-03-30 1991-03-28 Marc Genf/Geneve Ch Ballivet
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
KR100225087B1 (ko) 1990-03-23 1999-10-15 한스 발터라벤 피타아제의 식물내 발현
CA2082279C (en) 1990-05-09 2007-09-04 Grethe Rasmussen Cellulase preparation comprising an endoglucanase enzyme
DE4112440C1 (da) 1991-04-16 1992-10-22 Diagen Institut Fuer Molekularbiologische Diagnostik Gmbh, 4000 Duesseldorf, De
US5486461A (en) * 1991-11-08 1996-01-23 Novo Nordisk A/S Casein hydrolyzate and method for production of such casein hydrolyzate
ATE219143T1 (de) 1992-12-10 2002-06-15 Dsm Nv Herstellung von heterologen proteinen in filamentösen fungi
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5741665A (en) 1994-05-10 1998-04-21 University Of Hawaii Light-regulated promoters for production of heterologous proteins in filamentous fungi
DK0804558T3 (da) * 1994-11-08 2008-05-26 Novozymes As Tripeptidylaminopeptidase
CN1120235C (zh) 1996-03-27 2003-09-03 诺沃奇梅兹有限公司 碱性蛋白酶缺陷型丝状真菌
CA2329122A1 (en) 1999-03-26 2000-10-05 Diversa Corporation Exonuclease-mediated nucleic acid reassembly in directed evolution
PT1326957E (pt) * 2000-12-07 2004-09-30 Dsm Ip Assets Bv Metodo para a prevencao ou reducao de turvacao em bebidas
US7323327B2 (en) * 2001-02-23 2008-01-29 Dsm Ip Assets B.V. Genes encoding novel proteolytic enzymes
AU2003236689A1 (en) 2002-06-04 2003-12-19 Dsm Ip Assets B.V. Protein hydrolysate rich in tripeptides
US7648957B2 (en) * 2002-09-04 2010-01-19 Dsm Ip Assets B.V. Nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction
ES2599859T3 (es) * 2005-02-24 2017-02-03 Dsm Ip Assets B.V. Proceso enzimático para producir I-P-P a partir de caseína kappa
BRPI0610334A2 (pt) * 2005-04-28 2010-06-15 Dsm Ip Assets Bv hidrolisados de proteìnas que diminuem a pressão sangüìnea
WO2007044968A2 (en) 2005-10-12 2007-04-19 Genencor International, Inc. Stable, durable granules with active agents
US8592194B2 (en) 2007-10-09 2013-11-26 Danisco Us Inc. Glucoamylase variants with altered properties
CA2784944A1 (en) * 2009-12-21 2011-06-30 Centre Hospitalier Universitaire Vaudois Synergic action of a prolyl protease and tripeptidyl proteases
CA2852365C (en) * 2011-12-06 2021-01-26 Fondazione Istituto Insubrico Di Ricerca Per La Vita Proteases able to hydrolyze gluten peptides and proteins at acidic ph, from the actinomycete actinoallomurus.
EP2800809B1 (en) * 2012-01-05 2018-03-07 Glykos Finland Oy Protease deficient filamentous fungal cells and methods of use thereof
CN102771749B (zh) * 2012-07-16 2013-10-16 中国农业科学院农产品加工研究所 一种利用小麦面筋蛋白制备热反应肉味香精的方法

Also Published As

Publication number Publication date
EP3209774A1 (en) 2017-08-30
RU2741080C2 (ru) 2021-01-22
MX2017005268A (es) 2017-07-26
RU2017117858A (ru) 2018-11-26
BR112017008406A2 (pt) 2018-02-27
ES2791891T3 (es) 2020-11-06
WO2016062857A1 (en) 2016-04-28
CN107105707B (zh) 2022-07-22
US20180295858A1 (en) 2018-10-18
EP3209774B1 (en) 2020-02-26
US20200245642A1 (en) 2020-08-06
RU2017117858A3 (da) 2019-09-18
EP3209773A1 (en) 2017-08-30
CN107105709B (zh) 2021-04-30
ZA201702889B (en) 2020-07-29
CA2965423A1 (en) 2016-04-28
AU2015334890A1 (en) 2017-05-04
CA2965438A1 (en) 2016-04-28
US20220174981A1 (en) 2022-06-09
DK3209774T3 (da) 2020-05-25
EP3209773B1 (en) 2020-03-18
MX381014B (es) 2025-03-12
JP6878275B2 (ja) 2021-05-26
US20170325479A1 (en) 2017-11-16
JP2017534279A (ja) 2017-11-24
MX384226B (es) 2025-03-14
AU2015334890B2 (en) 2021-12-23
CN107105709A (zh) 2017-08-29
AU2015334892A1 (en) 2017-05-18
BR112017008304A2 (pt) 2018-05-15
WO2016062855A1 (en) 2016-04-28
CN107105707A (zh) 2017-08-29
MX2017005256A (es) 2017-07-24

Similar Documents

Publication Publication Date Title
FIC20230014I1 (fi) Foslevodopa ja foskarbidopa
DK3480213T3 (da) Syntac-polypeptider og anvendelser deraf
DK3218358T3 (da) Ifluorometyl-aminopyridiner og difluorometyl-aminopyrimidiner
DK3448386T3 (da) Isoquinolin-3-ylcarboxamider og fremstilling og anvendelse deraf
DK3229838T3 (da) Anti-C10orf54-antistoffer og anvendelser deraf
DK3126388T3 (da) Anti-EGFRvIII-antistoffer og anvendelser deraf
DK3189081T3 (da) Cd123-bindende midler og anvendelser deraf
DK3215147T3 (da) Neurodæmpende norketamin-forbindelser og fremgangsmåder
EP3205103C0 (en) INTER AND INTRA UNIFICATION BLOCK COPY
DK3237418T3 (da) Triazolopyrimidinforbindelser og anvendelser deraf
DK3212255T3 (da) Selvorienterende sprøjte og sprøjtegrænseflade
DK3210977T3 (da) Hidtil ukendt aminoalkylbenzothiazepinderivat og anvendelse deraf
DK3099172T3 (da) Modificeret biologisk bekæmpelsesmiddel og anvendelser deraf
DK3725357T3 (da) Opholdsstrukturer og relaterede fremgangsmåder
DK3015526T3 (da) Hydrofluorolefinbaseret sammensætning og anvendelse deraf
DK3161139T3 (da) Tlr-4-specifikke aptamerer og anvendelser heraf
DK3236991T3 (da) Fgf21-derivater og anvendelser deraf
DK3128005T3 (da) Sirp-alfa-variantkonstruktioner og anvendelser deraf
DK3110447T3 (da) Anti-EGFR-antistof og anvendelser heraf
DK3321279T3 (da) Exenatidmodificeringsmiddel og anvendelse deraf
DK3365321T3 (da) Solabegron-zwitterion og anvendelser deraf
DK3337506T3 (da) Kombinationer og anvendelser deraf
DK3245219T3 (da) Glypicanepitoper og anvendelser deraf
DK3102613T3 (da) Polymerpartikler og anvendelser deraf
DK3280405T3 (da) Inhibitorer og anvendelser deraf