MX2017005268A - Tripeptidil peptidasas tolerantes a prolina y usos de las mismas. - Google Patents

Tripeptidil peptidasas tolerantes a prolina y usos de las mismas.

Info

Publication number
MX2017005268A
MX2017005268A MX2017005268A MX2017005268A MX2017005268A MX 2017005268 A MX2017005268 A MX 2017005268A MX 2017005268 A MX2017005268 A MX 2017005268A MX 2017005268 A MX2017005268 A MX 2017005268A MX 2017005268 A MX2017005268 A MX 2017005268A
Authority
MX
Mexico
Prior art keywords
tolerant tripeptidyl
proline tolerant
proline
tripeptidyl peptidase
peptides
Prior art date
Application number
MX2017005268A
Other languages
English (en)
Other versions
MX384226B (es
Inventor
Edvard Degn Peter
Matthias Kragh Karsten
Eisele Thomas
Haaning Svend
Miasnikov Andrei
Ma Maria
Meinjohanns Ernst
Yde Bak Steffen
Original Assignee
Dupont Nutrition Biosci Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupont Nutrition Biosci Aps filed Critical Dupont Nutrition Biosci Aps
Publication of MX2017005268A publication Critical patent/MX2017005268A/es
Publication of MX384226B publication Critical patent/MX384226B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485—Exopeptidases (3.4.11-3.4.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C12Y304/14009—Tripeptidyl-peptidase I (3.4.14.9)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Fodder In General (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

Un método para producir un hidrolizado que comprende: (a) mezclar al menos una proteína o una porción de esta con: (A) al menos una endoproteasa; y (B) (a´) al menos una tripeptidil-peptidasa que tolera la prolina o fermentado que comprende una tripeptidil-peptidasa que tolera la prolina que tiene predominantemente actividad exopeptidasa, donde la tripeptidil-peptidasa que tolera la prolina es capaz de escindir tripéptidos del N-terminal de péptidos que tienen: prolina en P1, y aminoácidos sintéticos en P1; o (b´) al menos una tripeptidil-peptidasa que tolera la prolina que tiene actividad exopeptidasa donde la tripeptidil-peptidasa que tolera la prolina es capaz de escindir tripéptidos del N-terminal de péptidos que tienen: prolina en P1´; y aminoácidos sintéticos en P1´; y (b) recuperar el hidrolizado. La invención también se refiere amétodos para producir un hidrolizado que comprenden el uso de una endoproteasa, una exo-tripeptidil-peptidasa de la familia S53 y una aminopeptidasa, a usos de una tripeptidil-peptidasa que tolera la prolina, composiciones, composiciones de un aditivo alimentario y/o para piensos que la comprenden, así como también a hidrolizados y usus de tripeptidil-peptidasa que toleran la prolina.
MX2017005268A 2014-10-24 2015-10-23 Tripeptidil-peptidasas que toleran la prolina y sus usos. MX384226B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462068264P 2014-10-24 2014-10-24
US201462068243P 2014-10-24 2014-10-24
US201462068282P 2014-10-24 2014-10-24
US201462093301P 2014-12-17 2014-12-17
PCT/EP2015/074600 WO2016062855A1 (en) 2014-10-24 2015-10-23 Proline tolerant tripeptidyl peptidases and uses thereof

Publications (2)

Publication Number Publication Date
MX2017005268A true MX2017005268A (es) 2017-07-26
MX384226B MX384226B (es) 2025-03-14

Family

ID=54540018

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017005268A MX384226B (es) 2014-10-24 2015-10-23 Tripeptidil-peptidasas que toleran la prolina y sus usos.
MX2017005256A MX381014B (es) 2014-10-24 2015-10-23 Uso de tripeptidil-peptidasas que toleran la prolina en composiciones de un aditivo para piensos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2017005256A MX381014B (es) 2014-10-24 2015-10-23 Uso de tripeptidil-peptidasas que toleran la prolina en composiciones de un aditivo para piensos.

Country Status (13)

Country Link
US (4) US20180295858A1 (es)
EP (2) EP3209774B1 (es)
JP (1) JP6878275B2 (es)
CN (2) CN107105707B (es)
AU (2) AU2015334892A1 (es)
BR (2) BR112017008406A2 (es)
CA (2) CA2965438A1 (es)
DK (2) DK3209773T3 (es)
ES (1) ES2791891T3 (es)
MX (2) MX384226B (es)
RU (1) RU2741080C2 (es)
WO (2) WO2016062857A1 (es)
ZA (1) ZA201702889B (es)

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BR112019012937A2 (pt) 2016-12-23 2019-12-10 Heidelberg Pharma Research Gmbh novo conjugado de amanitina
WO2018224035A1 (en) * 2017-06-09 2018-12-13 Novozymes A/S Polypeptide, use and method for hydrolysing protein
CN107467370A (zh) * 2017-10-13 2017-12-15 无锡正大生物股份有限公司 一种饲料用功能性诱食剂及其制备方法
US10980253B2 (en) * 2017-12-28 2021-04-20 Global Earth Solutions, Llc Composition, system and method for pellet or flake production
EP3863596A4 (en) * 2018-10-11 2022-08-10 Imbria Pharmaceuticals, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF LEBERIAN OPTIC ATROPHY
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CN110551790B (zh) * 2019-07-29 2021-09-14 浙江大学 一种乳源活性肽的制备方法及应用
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LU504450B1 (en) * 2023-06-07 2024-12-09 Traceless Mat Gmbh Process for producing an animal feed
CN117491351B (zh) * 2023-12-27 2024-04-05 中国农业科学院北京畜牧兽医研究所 一种肉鸡饲料有效磷的仿生消化测定试剂盒和测定方法
CN118931885A (zh) * 2024-06-17 2024-11-12 深极美泰(山东)生物科技有限公司 一种金属蛋白酶Aquinlysin及其制备鳀鱼粉活性肽的应用

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Also Published As

Publication number Publication date
MX384226B (es) 2025-03-14
DK3209774T3 (da) 2020-05-25
RU2017117858A (ru) 2018-11-26
US20220174981A1 (en) 2022-06-09
AU2015334890A1 (en) 2017-05-04
BR112017008406A2 (pt) 2018-02-27
US20200245642A1 (en) 2020-08-06
CA2965423A1 (en) 2016-04-28
MX2017005256A (es) 2017-07-24
EP3209773B1 (en) 2020-03-18
EP3209773A1 (en) 2017-08-30
AU2015334890B2 (en) 2021-12-23
WO2016062855A1 (en) 2016-04-28
EP3209774B1 (en) 2020-02-26
AU2015334892A1 (en) 2017-05-18
BR112017008304A2 (pt) 2018-05-15
US20170325479A1 (en) 2017-11-16
US20180295858A1 (en) 2018-10-18
CN107105709A (zh) 2017-08-29
RU2741080C2 (ru) 2021-01-22
CN107105707B (zh) 2022-07-22
JP2017534279A (ja) 2017-11-24
DK3209773T3 (da) 2020-06-15
WO2016062857A1 (en) 2016-04-28
ZA201702889B (en) 2020-07-29
ES2791891T3 (es) 2020-11-06
JP6878275B2 (ja) 2021-05-26
CN107105709B (zh) 2021-04-30
CA2965438A1 (en) 2016-04-28
CN107105707A (zh) 2017-08-29
RU2017117858A3 (es) 2019-09-18
MX381014B (es) 2025-03-12
EP3209774A1 (en) 2017-08-30

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