DK3397273T3 - Forstærket syre-alfa-glucosidase til behandling af pompes sygdom - Google Patents

Forstærket syre-alfa-glucosidase til behandling af pompes sygdom Download PDF

Info

Publication number
DK3397273T3
DK3397273T3 DK16826898.5T DK16826898T DK3397273T3 DK 3397273 T3 DK3397273 T3 DK 3397273T3 DK 16826898 T DK16826898 T DK 16826898T DK 3397273 T3 DK3397273 T3 DK 3397273T3
Authority
DK
Denmark
Prior art keywords
glucosidase
alfa
disease
pump
treatment
Prior art date
Application number
DK16826898.5T
Other languages
English (en)
Inventor
Hung V Do
Richie Khanna
Russell Gotschall
Original Assignee
Amicus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amicus Therapeutics Inc filed Critical Amicus Therapeutics Inc
Priority claimed from PCT/US2016/069243 external-priority patent/WO2017117407A1/en
Application granted granted Critical
Publication of DK3397273T3 publication Critical patent/DK3397273T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0102—Alpha-glucosidase (3.2.1.20)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK16826898.5T 2015-12-30 2016-12-29 Forstærket syre-alfa-glucosidase til behandling af pompes sygdom DK3397273T3 (da)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562272890P 2015-12-30 2015-12-30
US201662300479P 2016-02-26 2016-02-26
US201662315412P 2016-03-30 2016-03-30
US201662402454P 2016-09-30 2016-09-30
US201662428867P 2016-12-01 2016-12-01
US201662431791P 2016-12-08 2016-12-08
PCT/US2016/069243 WO2017117407A1 (en) 2015-12-30 2016-12-29 Augmented acid alpha-glucosidase for the treatment of pompe disease

Publications (1)

Publication Number Publication Date
DK3397273T3 true DK3397273T3 (da) 2021-08-09

Family

ID=60186557

Family Applications (3)

Application Number Title Priority Date Filing Date
DK21174249.9T DK3957320T5 (da) 2015-12-30 2016-12-29 Forstærket syre-alfa-glucosidase til behandling af pompes sygdom
DK16826898.5T DK3397273T3 (da) 2015-12-30 2016-12-29 Forstærket syre-alfa-glucosidase til behandling af pompes sygdom
DK23188938.7T DK4285902T3 (da) 2015-12-30 2016-12-29 Forstærket syre-alfa-glucosidase til behandling af pompes sygdom

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK21174249.9T DK3957320T5 (da) 2015-12-30 2016-12-29 Forstærket syre-alfa-glucosidase til behandling af pompes sygdom

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK23188938.7T DK4285902T3 (da) 2015-12-30 2016-12-29 Forstærket syre-alfa-glucosidase til behandling af pompes sygdom

Country Status (16)

Country Link
EP (4) EP3397273B1 (da)
CN (1) CN108472340A (da)
CY (1) CY1124637T1 (da)
DK (3) DK3957320T5 (da)
ES (3) ES2965190T3 (da)
FI (2) FI3957320T3 (da)
HK (1) HK1253014A1 (da)
HR (3) HRP20210894T1 (da)
HU (2) HUE064049T2 (da)
LT (3) LT4285902T (da)
PL (3) PL3957320T3 (da)
PT (3) PT4285902T (da)
RS (3) RS62212B1 (da)
SI (2) SI3397273T1 (da)
SM (3) SMT202300412T1 (da)
TW (3) TWI849380B (da)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7723296B2 (en) * 2001-01-18 2010-05-25 Genzyme Corporation Methods for introducing mannose-6-phosphate and other oligosaccharides onto glycoproteins and its application thereof
PT2441467E (pt) 2003-01-31 2015-10-12 Sinai School Medicine Terapia combinada para o tratamento de transtornos associados a uma deficiência proteica
CN1922313B (zh) * 2004-02-10 2011-10-26 生物马林医药公司 酸性α-糖苷酶及其片段
EP2932982B1 (en) 2005-05-17 2018-10-03 Amicus Therapeutics, Inc. A method for the treatment of pompe disease using 1-deoxynojirimycin and derivatives
SI3470077T1 (sl) 2008-02-12 2020-12-31 Amicus Therapeutics, Inc. Postopek za napovedovanje odgovora na zdravljenje bolezni s farmakološkim spremljevalcem
US20110070643A1 (en) * 2009-05-26 2011-03-24 Do Hung V Utilization of Pharmacological Chaperones to Improve Manufacturing and Purification of Biologics
HRP20210398T1 (hr) 2012-05-03 2021-05-28 Amicus Therapeutics, Inc. Režimi doziranja za liječenje pompeove bolesti
HK1209625A1 (en) 2012-07-17 2016-04-08 Amicus Therapeutics, Inc. Alpha-galactosidase a and 1-deoxygalactonojirimycin co-formulation
WO2016054231A1 (en) * 2014-09-30 2016-04-07 Amicus Therapeutics, Inc. Highly potent acid alpha-glucosidase with enhanced carbohydrates

Also Published As

Publication number Publication date
LT4285902T (lt) 2026-02-25
EP3397273A1 (en) 2018-11-07
HRP20260120T1 (hr) 2026-03-13
TWI753874B (zh) 2022-02-01
SI3397273T1 (sl) 2021-11-30
FI4285902T3 (fi) 2026-02-17
SMT202600054T1 (it) 2026-03-09
EP3397273B1 (en) 2021-05-19
ES2883844T3 (es) 2021-12-09
ES2965190T3 (es) 2024-04-11
TWI849380B (zh) 2024-07-21
CN108472340A (zh) 2018-08-31
LT3957320T (lt) 2023-12-11
PL3957320T3 (pl) 2024-02-19
LT3397273T (lt) 2021-06-25
HRP20231465T1 (hr) 2024-03-01
PL3397273T3 (pl) 2021-12-06
EP4706779A2 (en) 2026-03-11
DK3957320T5 (da) 2024-08-05
TW201726163A (zh) 2017-08-01
HUE064049T2 (hu) 2024-02-28
RS67727B1 (sr) 2026-03-31
SMT202100452T1 (it) 2021-09-14
EP4285902A2 (en) 2023-12-06
CY1124637T1 (el) 2022-07-22
EP4285902A3 (en) 2024-02-21
DK3957320T3 (da) 2023-11-27
TW202506173A (zh) 2025-02-16
RS64843B1 (sr) 2023-12-29
SI3957320T1 (sl) 2024-01-31
EP4285902B1 (en) 2025-11-19
PT3397273T (pt) 2021-08-09
DK4285902T3 (da) 2026-02-16
EP3957320B1 (en) 2023-08-23
HUE054733T2 (hu) 2021-09-28
HRP20210894T1 (hr) 2021-07-23
TW202245831A (zh) 2022-12-01
PT3957320T (pt) 2023-11-23
RS62212B1 (sr) 2021-09-30
ES3063549T3 (en) 2026-04-17
SMT202300412T1 (it) 2024-01-10
EP3957320A1 (en) 2022-02-23
PL4285902T3 (pl) 2026-04-13
PT4285902T (pt) 2026-02-10
FI3957320T3 (fi) 2023-11-23
HK1253014A1 (zh) 2019-06-06

Similar Documents

Publication Publication Date Title
IL271956A (en) Blood pump
DK3912673T3 (da) Blodpumpe
DK3359214T3 (da) Blodpumpe
DK3212233T3 (da) Kombinationsterapi til behandling af sygdom
DK3424545T3 (da) Blodpumpe
DK3413948T3 (da) Blodpumpesystem
DK3795208T3 (da) Blodpumpe
DK3812001T3 (da) Blodpumpe
DK3821938T3 (da) Blodpumpe
DK3288581T3 (da) Fremgangsmåde til behandling af cancer
DK3240612T3 (da) Fremgangsmåder til behandling af nethindesygdomme
DK3362066T3 (da) Kombinationsterapi til behandling af maligniteter
IL247111A0 (en) Preventive or therapeutic agent for kidney disease
DK3390390T3 (da) Bipyrazolylderivater egnede til behandling af autoimmunsygdomme
PL3512642T3 (pl) Rozwiązanie bezmłotkowe
DK3148529T3 (da) Forbindelser til behandling af hjernecancer
HUE050944T2 (hu) Kezelési eljárás tradipitant alkalmazásával
DE112017004905A5 (de) Blutpumpe
DK3294283T3 (da) Sacubitril-valsartan-doseringsregime til behandling af hjerteinsufficiens
DK3324824T3 (da) Fremgangsmåde til behandling af binokulare dysfunktioner
HUE060517T2 (hu) Immunhiányos betegség kezelésére szolgáló eljárások
DK3307267T3 (da) Behandling af multipel sklerose
DK3468604T3 (da) Farmaceutiske kombinationer til behandling af cancer
DK3276177T3 (da) Spiralhuspumpe
DK3276178T3 (da) Spiralhuspumpe