LT3397273T - Patobulinta rūgštinė alfa-gliukozidazė pompe ligos gydymui - Google Patents

Patobulinta rūgštinė alfa-gliukozidazė pompe ligos gydymui

Info

Publication number
LT3397273T
LT3397273T LTEP16826898.5T LT16826898T LT3397273T LT 3397273 T LT3397273 T LT 3397273T LT 16826898 T LT16826898 T LT 16826898T LT 3397273 T LT3397273 T LT 3397273T
Authority
LT
Lithuania
Prior art keywords
glucosididase
acid
treatment
pompe disease
improved alpha
Prior art date
Application number
LTEP16826898.5T
Other languages
English (en)
Inventor
Hung V. Do
Richie Khanna
Russell GOTSCHALL
Original Assignee
Amicus Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amicus Therapeutics, Inc. filed Critical Amicus Therapeutics, Inc.
Priority claimed from PCT/US2016/069243 external-priority patent/WO2017117407A1/en
Publication of LT3397273T publication Critical patent/LT3397273T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0102—Alpha-glucosidase (3.2.1.20)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LTEP16826898.5T 2015-12-30 2016-12-29 Patobulinta rūgštinė alfa-gliukozidazė pompe ligos gydymui LT3397273T (lt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562272890P 2015-12-30 2015-12-30
US201662300479P 2016-02-26 2016-02-26
US201662315412P 2016-03-30 2016-03-30
US201662402454P 2016-09-30 2016-09-30
US201662428867P 2016-12-01 2016-12-01
US201662431791P 2016-12-08 2016-12-08
PCT/US2016/069243 WO2017117407A1 (en) 2015-12-30 2016-12-29 Augmented acid alpha-glucosidase for the treatment of pompe disease

Publications (1)

Publication Number Publication Date
LT3397273T true LT3397273T (lt) 2021-06-25

Family

ID=60186557

Family Applications (3)

Application Number Title Priority Date Filing Date
LTEP21174249.9T LT3957320T (lt) 2015-12-30 2016-12-29 Patobulinta rūgštinė alfa-gliukozidazė pompe ligos gydymui
LTEP16826898.5T LT3397273T (lt) 2015-12-30 2016-12-29 Patobulinta rūgštinė alfa-gliukozidazė pompe ligos gydymui
LTEP23188938.7T LT4285902T (lt) 2015-12-30 2016-12-29 Pagerinta rūgštinė alfa-gliukozidazė pompe ligos gydymui

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP21174249.9T LT3957320T (lt) 2015-12-30 2016-12-29 Patobulinta rūgštinė alfa-gliukozidazė pompe ligos gydymui

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP23188938.7T LT4285902T (lt) 2015-12-30 2016-12-29 Pagerinta rūgštinė alfa-gliukozidazė pompe ligos gydymui

Country Status (16)

Country Link
EP (4) EP4706779A3 (lt)
CN (1) CN108472340A (lt)
CY (1) CY1124637T1 (lt)
DK (3) DK3397273T3 (lt)
ES (3) ES3063549T3 (lt)
FI (2) FI3957320T3 (lt)
HK (1) HK1253014A1 (lt)
HR (3) HRP20231465T1 (lt)
HU (2) HUE054733T2 (lt)
LT (3) LT3957320T (lt)
PL (3) PL4285902T3 (lt)
PT (3) PT3397273T (lt)
RS (3) RS64843B1 (lt)
SI (3) SI3957320T1 (lt)
SM (3) SMT202600054T1 (lt)
TW (2) TWI753874B (lt)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7723296B2 (en) * 2001-01-18 2010-05-25 Genzyme Corporation Methods for introducing mannose-6-phosphate and other oligosaccharides onto glycoproteins and its application thereof
JP5589165B2 (ja) 2003-01-31 2014-09-17 マウント シナイ スクール オブ メディシン オブ ニューヨーク ユニバーシティー タンパク質欠損性障害の治療のための併用療法
DE602005020745D1 (de) * 2004-02-10 2010-06-02 Zystor Therapeutics Inc Saure alpha-glukosidase und fragmente davon
EP3782655A1 (en) 2005-05-17 2021-02-24 Amicus Therapeutics, Inc. A method for the treatment of pompe disease using 1-deoxynojirimycin and derivatives
WO2009102895A2 (en) 2008-02-12 2009-08-20 Amicus Therapeutics, Inc. Method to predict response to pharmacological chaperone treatment of diseases
EP2435459B1 (en) * 2009-05-26 2016-05-04 Amicus Therapeutics, Inc. Utilization of pharmacological chaperones to improve manufacturing and purification of acid beta-glucosidase
RS61598B1 (sr) 2012-05-03 2021-04-29 Amicus Therapeutics Inc Režimi doziranja za tretman pompeove bolesti
EP2874648A4 (en) 2012-07-17 2015-12-30 Amicus Therapeutics Inc ALPHA GALACTOSIDASE A AND 1-DEOXYGALACTONO JIRIMYCIN CO FORMULATION
JP6851964B2 (ja) * 2014-09-30 2021-03-31 アミカス セラピューティックス インコーポレイテッド 炭水化物が増大している非常に強力な酸性アルファ−グルコシダーゼ

Also Published As

Publication number Publication date
HUE064049T2 (hu) 2024-02-28
LT3957320T (lt) 2023-12-11
CN108472340A (zh) 2018-08-31
RS67727B1 (sr) 2026-03-31
RS64843B1 (sr) 2023-12-29
PL4285902T3 (pl) 2026-04-13
EP3397273A1 (en) 2018-11-07
TW202245831A (zh) 2022-12-01
DK3957320T3 (da) 2023-11-27
TW202506173A (zh) 2025-02-16
DK4285902T3 (da) 2026-02-16
SI3397273T1 (sl) 2021-11-30
EP4285902A2 (en) 2023-12-06
PL3397273T3 (pl) 2021-12-06
ES2883844T3 (es) 2021-12-09
EP3397273B1 (en) 2021-05-19
PT3957320T (pt) 2023-11-23
RS62212B1 (sr) 2021-09-30
PT4285902T (pt) 2026-02-10
CY1124637T1 (el) 2022-07-22
TWI753874B (zh) 2022-02-01
SI3957320T1 (sl) 2024-01-31
ES2965190T3 (es) 2024-04-11
EP4706779A3 (en) 2026-06-24
HRP20260120T1 (hr) 2026-03-13
PT3397273T (pt) 2021-08-09
SMT202100452T1 (it) 2021-09-14
FI4285902T3 (fi) 2026-02-17
PL3957320T3 (pl) 2024-02-19
EP4285902B1 (en) 2025-11-19
HK1253014A1 (zh) 2019-06-06
EP3957320A1 (en) 2022-02-23
TWI849380B (zh) 2024-07-21
TW201726163A (zh) 2017-08-01
HRP20231465T1 (hr) 2024-03-01
DK3957320T5 (da) 2024-08-05
SMT202300412T1 (it) 2024-01-10
HRP20210894T1 (hr) 2021-07-23
SI4285902T1 (sl) 2026-04-30
EP4285902A3 (en) 2024-02-21
LT4285902T (lt) 2026-02-25
EP3957320B1 (en) 2023-08-23
ES3063549T3 (en) 2026-04-17
EP4706779A2 (en) 2026-03-11
SMT202600054T1 (it) 2026-03-09
HUE054733T2 (hu) 2021-09-28
FI3957320T3 (fi) 2023-11-23
DK3397273T3 (da) 2021-08-09

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