DK341989A - Derivater af (1-hydroxy-2-piperidinylalkyl)-2-indoler, -2-quinolinoner, -2-benzo(b)azepioner, -2-benzimidazoloner eller 2-quinazolinoner, fremgangsmaade til fremstilling af saadanne forbindelser samt laegemiddel indeholdende disse - Google Patents

Derivater af (1-hydroxy-2-piperidinylalkyl)-2-indoler, -2-quinolinoner, -2-benzo(b)azepioner, -2-benzimidazoloner eller 2-quinazolinoner, fremgangsmaade til fremstilling af saadanne forbindelser samt laegemiddel indeholdende disse Download PDF

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Publication number
DK341989A
DK341989A DK341989A DK341989A DK341989A DK 341989 A DK341989 A DK 341989A DK 341989 A DK341989 A DK 341989A DK 341989 A DK341989 A DK 341989A DK 341989 A DK341989 A DK 341989A
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DK
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Prior art keywords
preparation
group
denotes
optionally substituted
hydrogen atom
Prior art date
Application number
DK341989A
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English (en)
Other versions
DK341989D0 (da
Inventor
Jonathan Frost
Patrick Lardenois
Jean Bertin
Alfred Saarmets
Corinne Rousselle
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8809449A external-priority patent/FR2634206B1/fr
Application filed by Synthelabo filed Critical Synthelabo
Publication of DK341989D0 publication Critical patent/DK341989D0/da
Publication of DK341989A publication Critical patent/DK341989A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Furan Compounds (AREA)
DK341989A 1988-07-12 1989-07-11 Derivater af (1-hydroxy-2-piperidinylalkyl)-2-indoler, -2-quinolinoner, -2-benzo(b)azepioner, -2-benzimidazoloner eller 2-quinazolinoner, fremgangsmaade til fremstilling af saadanne forbindelser samt laegemiddel indeholdende disse DK341989A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8809449A FR2634206B1 (fr) 1988-07-12 1988-07-12 Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2 et quinoleinones-2, leur preparation et leur application en therapeutique
FR888816373A FR2640266B2 (fr) 1988-07-12 1988-12-13 Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
DK341989D0 DK341989D0 (da) 1989-07-11
DK341989A true DK341989A (da) 1990-04-25

Family

ID=26226791

Family Applications (1)

Application Number Title Priority Date Filing Date
DK341989A DK341989A (da) 1988-07-12 1989-07-11 Derivater af (1-hydroxy-2-piperidinylalkyl)-2-indoler, -2-quinolinoner, -2-benzo(b)azepioner, -2-benzimidazoloner eller 2-quinazolinoner, fremgangsmaade til fremstilling af saadanne forbindelser samt laegemiddel indeholdende disse

Country Status (18)

Country Link
US (1) US5034401A (da)
EP (1) EP0351282B1 (da)
JP (1) JPH0272173A (da)
KR (1) KR900001684A (da)
AT (1) ATE96437T1 (da)
AU (1) AU618378B2 (da)
CA (1) CA1317292C (da)
DE (1) DE68910210T2 (da)
DK (1) DK341989A (da)
ES (1) ES2062064T3 (da)
FI (1) FI93012C (da)
FR (1) FR2640266B2 (da)
HU (1) HU201544B (da)
IE (1) IE62216B1 (da)
IL (1) IL90908A0 (da)
NO (1) NO174100C (da)
NZ (1) NZ229903A (da)
PT (1) PT91126B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182278A (en) * 1989-02-28 1993-01-26 Adir Et Compagnie Analgesic benzoxazolinones having at the 6-position a 1-hydroxy-3-morpholinopropyl side chain
CA2023492A1 (en) * 1989-08-31 1991-03-01 Barry Clifford Lange Herbicidal glutarimides
WO1991017156A1 (en) * 1990-05-10 1991-11-14 Pfizer Inc Neuroprotective indolone and related derivatives
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
FR2668149B1 (fr) * 1990-10-18 1994-09-23 Synthelabo Le 1-(3,4-dihydro-2-oxo-1h-quinolein-6-yl)-2-[4-(2-phenyl-ethyl)piperidin-1-yl]ethanol, sa preparation et son application en therapeutique.
TW197435B (da) * 1990-11-22 1993-01-01 Takeda Pharm Industry Co Ltd
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
FR2678270B1 (fr) * 1991-06-27 1995-01-13 Synthelabo Derives de 2-(piperidin-1-yl)ethanol, leur preparation et leur application en therapeutique.
EP0524846A1 (fr) * 1991-06-27 1993-01-27 Synthelabo Dérivés de 2-(pipéridin-1-y1) éthanol, leur préparation et leur application en thérapeutique
EP0594729A1 (en) * 1991-07-17 1994-05-04 Pfizer Inc. 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents
TW263504B (da) * 1991-10-03 1995-11-21 Pfizer
FR2684379B1 (fr) * 1991-12-02 1995-04-28 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique.
US5462934A (en) * 1992-03-09 1995-10-31 Takeda Chemical Industries Condensed heterocyclic ketone derivatives and their use
TW218875B (da) * 1992-03-09 1994-01-11 Takeda Pharm Industry Co Ltd
FR2688504B1 (fr) * 1992-03-13 1995-05-05 Synthelabo Derives de 2-(piperidin-1-yl)ethanol, leur preparation et leur application en therapeutique.
US6255322B1 (en) 1992-06-19 2001-07-03 Pfizer Inc. 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
DK0666854T3 (da) * 1992-10-30 1997-04-28 Pfizer Neurobeskyttende 3,4-dihydro-2(1H)-quinolon forbindelser
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
WO1995020587A1 (en) * 1994-01-31 1995-08-03 Pfizer Inc. Neuroprotective chroman compounds
ATE174915T1 (de) * 1994-10-31 1999-01-15 Merck Patent Gmbh Benzylpiperidinderivate mit hoher affinität zu bindungsstellen von aminosäure-rezeptoren
FR2738568B1 (fr) * 1995-09-08 1997-10-17 Synthelabo Derives de 4-(cycloalkyl)piperidines et 4-(cycloalkylalkyl) piperidines, leur preparation et leur application en therapeutique
SI0848707T1 (en) * 1995-09-08 2000-02-29 Sanofi-Synthelabo 4-(cycloalkyl)piperidines and 4-(cycloalkylalkyl)-piperidines derivatives, preparation thereof and therapeutical applications thereof
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
WO1999024422A1 (en) * 1997-11-05 1999-05-20 Neurosearch A/S Azaring-ether derivatives and their use as nicotinic ach receptor modulators
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
AR033485A1 (es) * 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
ES2691671T3 (es) 2010-06-24 2018-11-28 Alkermes Pharma Ireland Limited Profármacos de compuestos NH-acídicos: derivados de éster, carbonato, carbamato y fosfonato
MA41169A (fr) * 2014-12-17 2017-10-24 Acraf Composés antibactériens à large spectre d'activité

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3217011A (en) * 1965-05-07 1965-11-09 Sterling Drug Inc 1-(indolyglyoxalyl)-piperidines
JPS51125291A (en) * 1974-12-07 1976-11-01 Otsuka Pharmaceut Co Ltd A process for preparing novel carbostyryl derivatives
JPS51118772A (en) * 1975-04-09 1976-10-18 Otsuka Pharmaceut Co Ltd Method for preparing carbostyryl derivatives
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2528043A1 (fr) * 1982-06-03 1983-12-09 Roussel Uclaf Nouveaux derives de la 1,3-dihydro 4-/1-hydroxy-2-amino-ethyl/2h-indol-2-one, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2581993B1 (fr) * 1985-05-14 1988-03-18 Synthelabo Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique
US4788201A (en) * 1987-01-22 1988-11-29 Hoechst-Roussel Pharmaceuticals Inc. 3-methylenespiro (benzofuranpiperidines)

Also Published As

Publication number Publication date
AU3802989A (en) 1990-01-18
EP0351282B1 (fr) 1993-10-27
DK341989D0 (da) 1989-07-11
FI893365A7 (fi) 1990-01-13
HUT50328A (en) 1990-01-29
US5034401A (en) 1991-07-23
HU201544B (en) 1990-11-28
EP0351282A1 (fr) 1990-01-17
NO892870D0 (no) 1989-07-11
AU618378B2 (en) 1991-12-19
KR900001684A (ko) 1990-02-27
DE68910210D1 (de) 1993-12-02
IL90908A0 (en) 1990-02-09
ATE96437T1 (de) 1993-11-15
NZ229903A (en) 1991-04-26
DE68910210T2 (de) 1994-05-11
NO892870L (no) 1990-01-15
FR2640266B2 (fr) 1992-07-10
IE62216B1 (en) 1995-01-11
PT91126B (pt) 1994-12-30
NO174100C (no) 1994-03-16
CA1317292C (en) 1993-05-04
JPH0272173A (ja) 1990-03-12
NO174100B (no) 1993-12-06
FI893365A0 (fi) 1989-07-11
IE892237L (en) 1990-01-12
ES2062064T3 (es) 1994-12-16
FI93012B (fi) 1994-10-31
PT91126A (pt) 1990-02-08
FR2640266A2 (fr) 1990-06-15
FI93012C (fi) 1995-02-10

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