DK3419992T3 - Svampesystem til proteinproduktion med højt udbytte - Google Patents

Svampesystem til proteinproduktion med højt udbytte Download PDF

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Publication number
DK3419992T3
DK3419992T3 DK17717532.0T DK17717532T DK3419992T3 DK 3419992 T3 DK3419992 T3 DK 3419992T3 DK 17717532 T DK17717532 T DK 17717532T DK 3419992 T3 DK3419992 T3 DK 3419992T3
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DK
Denmark
Prior art keywords
high yield
protein production
yield protein
mushroom system
mushroom
Prior art date
Application number
DK17717532.0T
Other languages
English (en)
Inventor
Jurian Alexander Bronkhof
Jean-Paul Meijnen
Carola Bianca Michielse
Der Burgt Ismail Atalay Van
Jacob Visser
Johannes Heinrich Visser
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Application granted granted Critical
Publication of DK3419992T3 publication Critical patent/DK3419992T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2428Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477Hemicellulases not provided in a preceding group
    • C12N9/248Xylanases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01015Polygalacturonase (3.2.1.15)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01037Xylan 1,4-beta-xylosidase (3.2.1.37)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK17717532.0T 2016-02-22 2017-02-22 Svampesystem til proteinproduktion med højt udbytte DK3419992T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662298351P 2016-02-22 2016-02-22
PCT/US2017/018901 WO2017147163A1 (en) 2016-02-22 2017-02-22 Fungal high-level protein production system

Publications (1)

Publication Number Publication Date
DK3419992T3 true DK3419992T3 (da) 2021-02-15

Family

ID=58547785

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17717532.0T DK3419992T3 (da) 2016-02-22 2017-02-22 Svampesystem til proteinproduktion med højt udbytte

Country Status (6)

Country Link
US (1) US10072267B2 (da)
EP (1) EP3419992B1 (da)
CN (1) CN109661402B (da)
DK (1) DK3419992T3 (da)
ES (1) ES2855728T3 (da)
WO (1) WO2017147163A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017012913A (es) 2015-04-10 2018-06-06 Comet Biorefining Inc Metodos y composiciones para el tratamiento de biomasa celulosica y productos producidos por estos.
AU2019265921B2 (en) 2018-05-10 2024-12-19 Comet Biorefining Inc. Compositions comprising glucose and hemicellulose and their use
CN111748505B (zh) * 2019-03-28 2022-12-30 上海医药工业研究院 一种表达羧肽酶g2的基因工程菌及其制备方法和应用
AU2020276774B2 (en) 2019-05-10 2025-11-27 Comet Biorefining Inc. Materials and methods for producing arabinoxylan compositions
CN110484455B (zh) * 2019-06-10 2022-05-24 潍坊康地恩生物科技有限公司 一种稳定高产植酸酶的木霉突变菌株

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5811381A (en) 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
ES2237159T3 (es) 1998-10-06 2005-07-16 Mark Aaron Emalfarb Sistema de transformacion en el campo de los hongos micoticos filamentosos en chrysosporium.
JP2003180365A (ja) 2001-12-17 2003-07-02 National Research Inst Of Brewing 麹菌の固体培養時に発現する遺伝子の検出法
CA2498213C (en) 2002-09-10 2013-07-16 Genencor International, Inc. Induction of gene expression using a high concentration sugar mixture
AU2007342011A1 (en) * 2006-12-29 2008-07-10 Lifesensors, Inc. Methods and compositions for enhanced protein expression and purification
MX344810B (es) 2007-06-08 2017-01-09 Danisco Us Inc Genencor Div * Sistema de expresion de celulasa heterologa y homologa.
EP3421597B1 (en) 2009-03-16 2020-10-28 Danisco US Inc. Chrysosporium lucknowense protein production system
KR101181566B1 (ko) 2009-08-26 2012-09-10 성균관대학교산학협력단 SUMO-interacting motif (SIM)를 포함하는 단백질들의 SUMO modification을 증가시키는 SUMO-Ubc9 융합 단백질
ES2570382T3 (es) 2010-11-02 2016-05-18 Codexis Inc Composiciones y métodos para la producción de azúcares fermentables
CN103492561A (zh) 2011-03-17 2014-01-01 丹尼斯科美国公司 纤维素酶组合物和使用相同组合物用于改善木质纤维素生物质转化成可发酵糖的方法
RU2013146240A (ru) 2011-03-17 2015-04-27 ДАНИСКО ЮЭс ИНК. Ферменты гликозил-гидролазы и их применение для гидролиза биомассы
US9834804B2 (en) 2011-12-14 2017-12-05 Iogen Energy Corporation Fungal cells and fermentation processes
AU2013217568B2 (en) 2012-02-07 2018-09-27 Danisco Us Inc. Glycosylation as a stabilizer for phytase
WO2013159005A2 (en) 2012-04-19 2013-10-24 Dyadic International (Usa) Ltd. A method of improving the activity of cellulase enzyme mixtures in the saccharification of (ligno)cellulosic material
US10030221B2 (en) 2012-09-20 2018-07-24 Danisco Us Inc. Microtiter plates for controlled release of culture components to cell cultures
WO2014081700A1 (en) * 2012-11-20 2014-05-30 Codexis, Inc. Recombinant fungal polypeptides
EP3000880B9 (en) 2013-05-20 2019-05-15 Abengoa Bioenergía Nuevas Tecnologías, S. A. Expression of recombinant beta-xylosidase enzymes
CA2971187C (en) 2014-12-16 2023-10-24 Danisco Us Inc. Fungal genome modification systems and methods of use

Also Published As

Publication number Publication date
CN109661402B (zh) 2022-06-28
US10072267B2 (en) 2018-09-11
EP3419992B1 (en) 2020-11-18
BR112018015626A2 (pt) 2018-12-26
EP3419992A1 (en) 2019-01-02
US20170240909A1 (en) 2017-08-24
CN109661402A (zh) 2019-04-19
WO2017147163A1 (en) 2017-08-31
ES2855728T3 (es) 2021-09-24

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