DK3484599T3 - Oprensningsfremgangsmåde og anvendelser deraf - Google Patents
Oprensningsfremgangsmåde og anvendelser deraf Download PDFInfo
- Publication number
- DK3484599T3 DK3484599T3 DK17735571.6T DK17735571T DK3484599T3 DK 3484599 T3 DK3484599 T3 DK 3484599T3 DK 17735571 T DK17735571 T DK 17735571T DK 3484599 T3 DK3484599 T3 DK 3484599T3
- Authority
- DK
- Denmark
- Prior art keywords
- purification process
- purification
- Prior art date
Links
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/30—Partition chromatography
- B01D15/305—Hydrophilic interaction chromatography [HILIC]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3847—Multimodal interactions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6034—Construction of the column joining multiple columns
- G01N30/6039—Construction of the column joining multiple columns in series
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/428—Frontal mode
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6052—Construction of the column body
- G01N30/6069—Construction of the column body with compartments or bed substructure
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16179273 | 2016-07-13 | ||
| PCT/EP2017/067190 WO2018011102A1 (en) | 2016-07-13 | 2017-07-10 | Purification method and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3484599T3 true DK3484599T3 (da) | 2020-06-15 |
Family
ID=56418392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17735571.6T DK3484599T3 (da) | 2016-07-13 | 2017-07-10 | Oprensningsfremgangsmåde og anvendelser deraf |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11180526B2 (da) |
| EP (1) | EP3484599B1 (da) |
| CN (1) | CN109475789B (da) |
| DK (1) | DK3484599T3 (da) |
| WO (1) | WO2018011102A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10432559B2 (en) | 2016-10-24 | 2019-10-01 | Snap Inc. | Generating and displaying customized avatars in electronic messages |
| EP3546475A1 (en) * | 2018-03-27 | 2019-10-02 | Sanofi | Full flow-through process for purifying recombinant proteins |
| MY204234A (en) | 2018-08-27 | 2024-08-16 | Regeneron Pharma | Use of raman spectroscopy in downstream purification |
| EP3991820A1 (en) * | 2020-11-03 | 2022-05-04 | Sartorius Stedim Biotech GmbH | System for membrane chromatography |
| CN112451996B (zh) * | 2020-11-10 | 2021-09-24 | 浙江大学 | 一种多柱连续流层析捕获蛋白的优化方法 |
| EP4408561B1 (en) * | 2021-09-28 | 2025-04-16 | ChromaCon AG | Purification method and uses thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3220164A (en) * | 1962-07-18 | 1965-11-30 | Perkin Elmer Corp | Recirculation chromatography |
| CA2044242A1 (en) * | 1989-10-27 | 1991-04-28 | Pall Corporation | Sorbing apparatus with guard bed |
| DE19711173A1 (de) | 1997-03-18 | 1998-09-24 | Sartorius Gmbh | Verfahren und Anlage für die adsorptive Stofftrennung |
| DE19812821B4 (de) * | 1998-03-24 | 2006-09-07 | Forschungszentrum Jülich GmbH | Vorrichtung und Verfahren für frontchromatographische Dekontamination |
| US7901581B2 (en) | 2007-06-15 | 2011-03-08 | Ge Healthcare Bio-Sciences Ab | Chromatography method |
| CA2748348A1 (en) * | 2009-01-06 | 2010-07-15 | Chromacon Ag | Multifraction purification processes and devices for such processes |
| US7988859B2 (en) * | 2009-02-05 | 2011-08-02 | Chromatan Inc. | Countercurrent tangential chromatography methods, systems, and apparatus |
| KR101152036B1 (ko) | 2010-04-27 | 2012-06-08 | (주)셀트리온 | 컬럼 순환 및 시료 연속주입법을 이용한 단백질 a 크로마토그래피 정제 방법 |
| EP2500073A1 (en) * | 2011-03-17 | 2012-09-19 | ChromaCon AG | Method for identification and purification of multi-specific polypeptides |
| WO2013083482A1 (en) | 2011-12-05 | 2013-06-13 | Chromacon Ag | Chromatographic method for the separation of fatty acid mixtures |
| DK2772289T3 (da) * | 2013-03-01 | 2015-08-10 | Chromacon Ag | Kromatografisk fremgangsmåde til berigelse og isolering |
| US10948483B2 (en) * | 2013-04-08 | 2021-03-16 | Chromacon Ag | Method for control, monitoring and/or optimization of a chromatographic process |
| US10099156B2 (en) | 2013-04-08 | 2018-10-16 | Chromacon Ag | Chromatographic purification method |
| CN103331036B (zh) * | 2013-06-21 | 2014-11-26 | 浙江大学宁波理工学院 | 一种从混合物中分离与富集目标组分的色谱分离方法 |
| US20160074775A1 (en) * | 2014-09-11 | 2016-03-17 | Pall Corporation | Continuous chromatography method and system |
-
2017
- 2017-07-10 US US16/071,277 patent/US11180526B2/en active Active
- 2017-07-10 CN CN201780043052.9A patent/CN109475789B/zh active Active
- 2017-07-10 WO PCT/EP2017/067190 patent/WO2018011102A1/en not_active Ceased
- 2017-07-10 EP EP17735571.6A patent/EP3484599B1/en active Active
- 2017-07-10 DK DK17735571.6T patent/DK3484599T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3484599A1 (en) | 2019-05-22 |
| CN109475789A (zh) | 2019-03-15 |
| US20200031863A1 (en) | 2020-01-30 |
| CN109475789B (zh) | 2020-06-05 |
| EP3484599B1 (en) | 2020-04-22 |
| US11180526B2 (en) | 2021-11-23 |
| WO2018011102A1 (en) | 2018-01-18 |
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