DK3500571T3 - Imidazo[1,2-a]pyridinforbindelser, sammensætninger omfattende disse, fremgangsmåder til behandling af sygdomme ved hjælp af disse og fremgangsmåder til fremstilling heraf - Google Patents

Imidazo[1,2-a]pyridinforbindelser, sammensætninger omfattende disse, fremgangsmåder til behandling af sygdomme ved hjælp af disse og fremgangsmåder til fremstilling heraf Download PDF

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Publication number
DK3500571T3
DK3500571T3 DK17821743.6T DK17821743T DK3500571T3 DK 3500571 T3 DK3500571 T3 DK 3500571T3 DK 17821743 T DK17821743 T DK 17821743T DK 3500571 T3 DK3500571 T3 DK 3500571T3
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DK
Denmark
Prior art keywords
imidazo
diseases
procedures
manufacture
treatment
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Application number
DK17821743.6T
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English (en)
Inventor
Daniel T Starczynowski
Craig J Thomas
Garrett Rhyasen
Katelyn Melgar
Morgan Mackenzie Walker
Jian-Kang Jiang
Original Assignee
Childrens Hospital Med Ct
Us Health
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Publication of DK3500571T3 publication Critical patent/DK3500571T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK17821743.6T 2016-08-17 2017-08-16 Imidazo[1,2-a]pyridinforbindelser, sammensætninger omfattende disse, fremgangsmåder til behandling af sygdomme ved hjælp af disse og fremgangsmåder til fremstilling heraf DK3500571T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662375965P 2016-08-17 2016-08-17
PCT/US2017/047088 WO2018038988A2 (en) 2016-08-17 2017-08-16 Compounds, compositions, methods for treating diseases, and methods for preparing compounds

Publications (1)

Publication Number Publication Date
DK3500571T3 true DK3500571T3 (da) 2021-03-08

Family

ID=60812120

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17821743.6T DK3500571T3 (da) 2016-08-17 2017-08-16 Imidazo[1,2-a]pyridinforbindelser, sammensætninger omfattende disse, fremgangsmåder til behandling af sygdomme ved hjælp af disse og fremgangsmåder til fremstilling heraf

Country Status (9)

Country Link
US (1) US20220213094A1 (da)
EP (2) EP3854796A1 (da)
CA (1) CA3033755A1 (da)
DK (1) DK3500571T3 (da)
ES (1) ES2862314T3 (da)
LT (1) LT3500571T (da)
PL (1) PL3500571T3 (da)
PT (1) PT3500571T (da)
WO (1) WO2018038988A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11542261B2 (en) * 2016-08-17 2023-01-03 Children's Hospital Medical Center Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors
CA3124088A1 (en) * 2018-12-20 2020-06-25 Incyte Corporation Imidazopyridazine and imidazopyridine compounds as inhibitors of activin receptor-like kinase-2
WO2021126779A1 (en) * 2019-12-18 2021-06-24 The Regents Of The University Of California Inhibitors of lin28 and methods of use thereof
EP4188926A4 (en) * 2020-07-31 2024-08-21 Children's Hospital Medical Center Multi-cyclic irak and flt3 inhibiting compounds and uses thereof
WO2022140647A1 (en) * 2020-12-23 2022-06-30 Children's Hospital Medical Center Multi-cyclic irak and flt3 inhibiting compounds and uses thereof
IL310425A (en) * 2021-07-30 2024-03-01 Childrens Hospital Med Ct Multi-cyclic irak and flt3 inhibiting compounds and uses thereof
WO2023116888A1 (zh) * 2021-12-23 2023-06-29 杭州多域生物技术有限公司 一种五元并六元化合物、制备方法、药物组合物和应用
AU2023283393A1 (en) * 2022-06-10 2025-01-02 Interline Therapeutics, Inc. Imidazo(1,2-a)pyridine derivatives as ripk2 inhibitors
WO2023250431A2 (en) * 2022-06-22 2023-12-28 Children's Hospital Medical Center Multi-cyclic irak and flt3 inhibiting compounds and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015076800A1 (en) * 2013-11-21 2015-05-28 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine bmi-1 inhibitors

Also Published As

Publication number Publication date
PT3500571T (pt) 2021-03-29
EP3500571B1 (en) 2020-12-30
CA3033755A1 (en) 2018-03-01
WO2018038988A2 (en) 2018-03-01
PL3500571T3 (pl) 2021-06-28
US20220213094A1 (en) 2022-07-07
WO2018038988A3 (en) 2018-04-05
EP3500571A2 (en) 2019-06-26
ES2862314T3 (es) 2021-10-07
EP3854796A1 (en) 2021-07-28
LT3500571T (lt) 2021-04-12

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