PT3500571T - Compostos de imidazo[1,2-a] piridina, composições que os compreendem, métodos para o uso no tratamento de doenças e seus métodos de preparação - Google Patents

Compostos de imidazo[1,2-a] piridina, composições que os compreendem, métodos para o uso no tratamento de doenças e seus métodos de preparação

Info

Publication number
PT3500571T
PT3500571T PT178217436T PT17821743T PT3500571T PT 3500571 T PT3500571 T PT 3500571T PT 178217436 T PT178217436 T PT 178217436T PT 17821743 T PT17821743 T PT 17821743T PT 3500571 T PT3500571 T PT 3500571T
Authority
PT
Portugal
Prior art keywords
methods
imidazo
compositions
preparing
treating diseases
Prior art date
Application number
PT178217436T
Other languages
English (en)
Original Assignee
Childrens Hospital Med Ct
The U S A As Represented By The Secretary Department Of Health And Human Services Office Of Tech Tra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Hospital Med Ct, The U S A As Represented By The Secretary Department Of Health And Human Services Office Of Tech Tra filed Critical Childrens Hospital Med Ct
Publication of PT3500571T publication Critical patent/PT3500571T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT178217436T 2016-08-17 2017-08-16 Compostos de imidazo[1,2-a] piridina, composições que os compreendem, métodos para o uso no tratamento de doenças e seus métodos de preparação PT3500571T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662375965P 2016-08-17 2016-08-17

Publications (1)

Publication Number Publication Date
PT3500571T true PT3500571T (pt) 2021-03-29

Family

ID=60812120

Family Applications (1)

Application Number Title Priority Date Filing Date
PT178217436T PT3500571T (pt) 2016-08-17 2017-08-16 Compostos de imidazo[1,2-a] piridina, composições que os compreendem, métodos para o uso no tratamento de doenças e seus métodos de preparação

Country Status (9)

Country Link
US (1) US20220213094A1 (pt)
EP (2) EP3500571B1 (pt)
CA (1) CA3033755A1 (pt)
DK (1) DK3500571T3 (pt)
ES (1) ES2862314T3 (pt)
LT (1) LT3500571T (pt)
PL (1) PL3500571T3 (pt)
PT (1) PT3500571T (pt)
WO (1) WO2018038988A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11542261B2 (en) * 2016-08-17 2023-01-03 Children's Hospital Medical Center Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors
CA3124088A1 (en) * 2018-12-20 2020-06-25 Incyte Corporation Imidazopyridazine and imidazopyridine compounds as inhibitors of activin receptor-like kinase-2
CN120025336A (zh) * 2019-12-18 2025-05-23 加利福尼亚大学董事会 Lin28抑制剂和其使用方法
JP2023538242A (ja) * 2020-07-31 2023-09-07 チルドレンズ ホスピタル メディカル センター 多環式ｉｒａｋ及びｆｌｔ３阻害化合物、並びにその使用
CA3201841A1 (en) * 2020-12-23 2022-06-30 Scott Bryan HOYT Multi-cyclic irak and flt3 inhibiting compounds and uses thereof
IL310425A (en) * 2021-07-30 2024-03-01 Childrens Hospital Med Ct Multi-cyclic irak and flt3 inhibiting compounds and uses thereof
WO2023116888A1 (zh) * 2021-12-23 2023-06-29 杭州多域生物技术有限公司 一种五元并六元化合物、制备方法、药物组合物和应用
CA3258667A1 (en) * 2022-06-10 2023-12-14 Interline Therapeutics Inc. IMIDAZO(1,2-A)PYRIDINE DERIVATIVES USED AS RIPK2 INHIBITORS
WO2023250431A2 (en) * 2022-06-22 2023-12-28 Children's Hospital Medical Center Multi-cyclic irak and flt3 inhibiting compounds and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015076800A1 (en) * 2013-11-21 2015-05-28 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine bmi-1 inhibitors

Also Published As

Publication number Publication date
WO2018038988A2 (en) 2018-03-01
EP3500571B1 (en) 2020-12-30
LT3500571T (lt) 2021-04-12
PL3500571T3 (pl) 2021-06-28
ES2862314T3 (es) 2021-10-07
WO2018038988A3 (en) 2018-04-05
US20220213094A1 (en) 2022-07-07
EP3854796A1 (en) 2021-07-28
CA3033755A1 (en) 2018-03-01
DK3500571T3 (da) 2021-03-08
EP3500571A2 (en) 2019-06-26

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