DK3523310T3 - Krystallinske polymorfer af en muscarinacetylcholinreceptoragonist - Google Patents

Krystallinske polymorfer af en muscarinacetylcholinreceptoragonist Download PDF

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Publication number: DK3523310T3
Authority: DK; Denmark
Prior art keywords: muscarinacetylcholine; receptor agonist; crystalline polymorphs; polymorphs; crystalline
Prior art date: 2016-10-05

Application number

DK17788131.5T

Other languages

English (en)

Inventor

Abraham Fisher

Nira Bar-Ner

Manfred Windisch

Original Assignee

Nsc Therapeutics Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-10-05

Filing date

2017-10-05

Publication date

2022-08-08

2017-10-05 Application filed by Nsc Therapeutics Gmbh filed Critical Nsc Therapeutics Gmbh

2022-08-08 Application granted granted Critical

2022-08-08 Publication of DK3523310T3 publication Critical patent/DK3523310T3/da

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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/10—Spiro-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Ophthalmology & Optometry (AREA)
Epidemiology (AREA)
Obesity (AREA)
Psychiatry (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Immunology (AREA)
Endocrinology (AREA)
Psychology (AREA)
Toxicology (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Addiction (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Child & Adolescent Psychology (AREA)
Physical Education & Sports Medicine (AREA)
Hospice & Palliative Care (AREA)

DK17788131.5T 2016-10-05 2017-10-05 Krystallinske polymorfer af en muscarinacetylcholinreceptoragonist DK3523310T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP16192494		2016-10-05
PCT/EP2017/075373 WO2018065529A1 (en)	2016-10-05	2017-10-05	Crystalline polymorphs of a muscarinic acetylcholine receptor agonist

Publications (1)

Publication Number	Publication Date
DK3523310T3 true DK3523310T3 (da)	2022-08-08

Family

ID=57083221

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK17788131.5T DK3523310T3 (da)	2016-10-05	2017-10-05	Krystallinske polymorfer af en muscarinacetylcholinreceptoragonist

Country Status (30)

Country	Link
US (3)	US11008342B2 (da)
EP (1)	EP3523310B1 (da)
JP (3)	JP7163280B2 (da)
KR (1)	KR102710640B1 (da)
CN (1)	CN109790180A (da)
AU (1)	AU2017341088B2 (da)
CA (1)	CA3036134A1 (da)
CL (1)	CL2019000532A1 (da)
CO (1)	CO2019003003A2 (da)
CY (1)	CY1125464T1 (da)
DK (1)	DK3523310T3 (da)
EA (1)	EA201990376A1 (da)
ES (1)	ES2924432T3 (da)
HR (1)	HRP20220962T1 (da)
HU (1)	HUE059720T2 (da)
IL (2)	IL265747B2 (da)
LT (1)	LT3523310T (da)
MA (1)	MA46464B1 (da)
MD (1)	MD3523310T2 (da)
MX (1)	MX383581B (da)
PE (2)	PE20250745A1 (da)
PH (1)	PH12019550048B1 (da)
PL (1)	PL3523310T3 (da)
PT (1)	PT3523310T (da)
RS (1)	RS63438B1 (da)
SG (1)	SG11201901612TA (da)
SI (1)	SI3523310T1 (da)
SM (1)	SMT202200331T1 (da)
WO (1)	WO2018065529A1 (da)
ZA (1)	ZA201901695B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SMT202200331T1 (it) *	2016-10-05	2022-09-14	Nsc Therapeutics Gmbh	Polimorfi cristallini di un agonista di recettore muscarinico di acetilcolina
WO2019180224A1 (en)	2018-03-22	2019-09-26	Nsc Therapeutics Gmbh	Compounds and methods for use in the treatment of microglia-mediated disorders
US20220233512A1 (en) *	2020-11-03	2022-07-28	Cassava Sciences, Inc.	Inhibiting an immune response mediated by one or more of tlr2, rage, ccr5, cxcr4 and cd4

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4855290A (en)	1985-05-10	1989-08-08	State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research	Derivatives of quinuclidine
US5534520A (en) *	1990-04-10	1996-07-09	Fisher; Abraham	Spiro compounds containing five-membered rings
US6797558B2 (en)	2001-04-24	2004-09-28	Micron Technology, Inc.	Methods of forming a capacitor with substantially selective deposite of polysilicon on a substantially crystalline capacitor dielectric layer
EP1395257A1 (en) *	2001-06-12	2004-03-10	Elan Pharmaceuticals, Inc.	Macrocycles useful in the treatment of alzheimer's disease
AU2003223093B2 (en) *	2002-05-03	2010-02-04	Israel Institute For Biological Research	Methods and compositions for treatment of central and peripheral nervous system disorders and novel compounds useful therefor
WO2010051497A1 (en) *	2008-10-31	2010-05-06	Pain Therapeutics, Inc.	Filamin a binding anti-inflammatory and analgesic
SMT202200331T1 (it)	2016-10-05	2022-09-14	Nsc Therapeutics Gmbh	Polimorfi cristallini di un agonista di recettore muscarinico di acetilcolina
WO2019180224A1 (en)	2018-03-22	2019-09-26	Nsc Therapeutics Gmbh	Compounds and methods for use in the treatment of microglia-mediated disorders

2017
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- 2017-10-05 PH PH1/2019/550048A patent/PH12019550048B1/en unknown
- 2017-10-05 WO PCT/EP2017/075373 patent/WO2018065529A1/en not_active Ceased
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- 2017-10-05 PE PE2024002026A patent/PE20250745A1/es unknown
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- 2017-10-05 HR HRP20220962TT patent/HRP20220962T1/hr unknown
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- 2017-10-05 RS RS20220724A patent/RS63438B1/sr unknown
2019
- 2019-02-28 CL CL2019000532A patent/CL2019000532A1/es unknown
- 2019-03-19 ZA ZA2019/01695A patent/ZA201901695B/en unknown
- 2019-03-28 CO CONC2019/0003003A patent/CO2019003003A2/es unknown
2020
- 2020-12-22 US US17/130,564 patent/US11866449B2/en active Active
2022
- 2022-05-18 JP JP2022081233A patent/JP2022119840A/ja active Pending
- 2022-08-04 CY CY20221100533T patent/CY1125464T1/el unknown
2023
- 2023-06-28 IL IL304126A patent/IL304126A/en unknown
- 2023-11-21 US US18/516,585 patent/US20240083914A1/en active Pending
2024
- 2024-01-24 JP JP2024008595A patent/JP2024056724A/ja active Pending

Also Published As

Publication number	Publication date
LT3523310T (lt)	2022-08-25
MX383581B (es)	2025-03-14
PT3523310T (pt)	2022-08-04
CA3036134A1 (en)	2018-04-12
AU2017341088A1 (en)	2019-04-04
US11008342B2 (en)	2021-05-18
CL2019000532A1 (es)	2019-07-12
CY1125464T1 (el)	2025-05-09
PH12019550048A1 (en)	2019-07-24
JP7163280B2 (ja)	2022-10-31
SG11201901612TA (en)	2019-03-28
WO2018065529A1 (en)	2018-04-12
KR20190056398A (ko)	2019-05-24
MA46464B1 (fr)	2022-10-31
MD3523310T2 (ro)	2022-10-31
IL265747B2 (en)	2023-12-01
IL265747B1 (en)	2023-08-01
US20240083914A1 (en)	2024-03-14
CO2019003003A2 (es)	2019-04-12
EP3523310A1 (en)	2019-08-14
EP3523310B1 (en)	2022-05-18
US20200040007A1 (en)	2020-02-06
BR112019005450A2 (pt)	2019-06-18
HUE059720T2 (hu)	2022-12-28
ZA201901695B (en)	2021-08-25
JP2024056724A (ja)	2024-04-23
SI3523310T1 (sl)	2022-10-28
US20210238195A1 (en)	2021-08-05
MA46464A (fr)	2021-05-26
RS63438B1 (sr)	2022-08-31
KR102710640B1 (ko)	2024-09-27
PE20191003A1 (es)	2019-07-15
NZ751538A (en)	2024-10-25
SMT202200331T1 (it)	2022-09-14
IL265747A (en)	2019-06-30
EA201990376A1 (ru)	2019-11-29
HRP20220962T1 (hr)	2022-10-28
PL3523310T3 (pl)	2022-08-29
US11866449B2 (en)	2024-01-09
IL304126A (en)	2023-09-01
PH12019550048B1 (en)	2023-12-06
JP2019529389A (ja)	2019-10-17
CN109790180A (zh)	2019-05-21
AU2017341088B2 (en)	2021-06-24
JP2022119840A (ja)	2022-08-17
ES2924432T3 (es)	2022-10-06
MX2019003748A (es)	2019-08-12
PE20250745A1 (es)	2025-03-13

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