DK355889D0 - Syntetisk peptid og farmaceutisk middel indeholdende peptidet - Google Patents

Syntetisk peptid og farmaceutisk middel indeholdende peptidet

Info

Publication number: DK355889D0
Authority: DK; Denmark
Prior art keywords: ala; arg; leu; gln; phe
Prior art date: 1988-07-22

Application number

DK355889A

Other languages

English (en)

Other versions

DK355889A (da

Inventor

Jean Edouard Frederic Rivier

Catherine Laure Rivier

Jr Wylie Walker Vale

Original Assignee

Salk Inst For Biological Studi

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-07-22

Filing date

1989-07-18

Publication date

1989-07-18

1989-07-18 Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi

1989-07-18 Publication of DK355889D0 publication Critical patent/DK355889D0/da

1990-01-23 Publication of DK355889A publication Critical patent/DK355889A/da

Links

239000003814 drug Substances 0.000 title 1
-1 Met Chemical compound 0.000 abstract 4
FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical compound CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 abstract 2
OUYCCCASQSFEME-MRVPVSSYSA-N D-tyrosine Chemical compound OC(=O)[C@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-MRVPVSSYSA-N 0.000 abstract 2
COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
XKCWNEVAXQCMGP-RXMQYKEDSA-N (2R)-2-amino-5-[carbamimidoyl(methyl)amino]pentanoic acid Chemical compound CN(CCC[C@@H](N)C(O)=O)C(N)=N XKCWNEVAXQCMGP-RXMQYKEDSA-N 0.000 abstract 1
CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Chemical group OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 abstract 1
QNAYBMKLOCPYGJ-UWTATZPHSA-N D-alanine Chemical compound C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 abstract 1
QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Chemical group CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 abstract 1
ODKSFYDXXFIFQN-SCSAIBSYSA-N D-arginine Chemical compound OC(=O)[C@H](N)CCCNC(N)=N ODKSFYDXXFIFQN-SCSAIBSYSA-N 0.000 abstract 1
CKLJMWTZIZZHCS-UWTATZPHSA-N D-aspartic acid Chemical group OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 abstract 1
HNDVDQJCIGZPNO-RXMQYKEDSA-N D-histidine Chemical compound OC(=O)[C@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-RXMQYKEDSA-N 0.000 abstract 1
KDXKERNSBIXSRK-RXMQYKEDSA-N D-lysine Chemical compound NCCCC[C@@H](N)C(O)=O KDXKERNSBIXSRK-RXMQYKEDSA-N 0.000 abstract 1
COLNVLDHVKWLRT-MRVPVSSYSA-N D-phenylalanine Chemical compound OC(=O)[C@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-MRVPVSSYSA-N 0.000 abstract 1
SGCGMORCWLEJNZ-UWVGGRQHSA-N His-His Chemical compound C([C@H]([NH3+])C(=O)N[C@@H](CC=1NC=NC=1)C([O-])=O)C1=CN=CN1 SGCGMORCWLEJNZ-UWVGGRQHSA-N 0.000 abstract 1
DEFJQIDDEAULHB-IMJSIDKUSA-N L-alanyl-L-alanine Chemical group C[C@H](N)C(=O)N[C@@H](C)C(O)=O DEFJQIDDEAULHB-IMJSIDKUSA-N 0.000 abstract 1
ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 1
KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical group NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 abstract 1
210000004899 c-terminal region Anatomy 0.000 abstract 1
230000007515 enzymatic degradation Effects 0.000 abstract 1
125000000267 glycino group Chemical group [H]N([*])C([H])([H])C(=O)O[H] 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
230000001817 pituitary effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Endocrinology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Amplifiers (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Luminescent Compositions (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Control Of El Displays (AREA)

DK355889A 1988-07-22 1989-07-18 Syntetisk peptid og farmaceutisk middel indeholdende peptidet DK355889A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/223,277 US5043322A (en)	1988-07-22	1988-07-22	Cyclic GRF analogs

Publications (2)

Publication Number	Publication Date
DK355889D0 true DK355889D0 (da)	1989-07-18
DK355889A DK355889A (da)	1990-01-23

Family

ID=22835815

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK355889A DK355889A (da)	1988-07-22	1989-07-18	Syntetisk peptid og farmaceutisk middel indeholdende peptidet

Country Status (13)

Country	Link
US (1)	US5043322A (da)
EP (1)	EP0352014B1 (da)
JP (1)	JP2739910B2 (da)
KR (1)	KR0138907B1 (da)
AT (1)	ATE103609T1 (da)
DE (1)	DE68914205T2 (da)
DK (1)	DK355889A (da)
ES (1)	ES2055792T3 (da)
FI (1)	FI91074C (da)
IE (1)	IE892378L (da)
IL (1)	IL90766A0 (da)
NO (1)	NO892970L (da)
ZA (1)	ZA895050B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2119800C1 (ru) *	1990-11-14	1998-10-10	Дзе Апджон Компани	Аналог пептида фактора гормона роста (фгр), способ стимулирования секреции гормона роста и композиция для стимулирования секреции
CA2084061A1 (en) *	1991-04-09	1992-10-10	Arthur M. Felix	Growth hormone releasing factor analogs
US5262519A (en) *	1991-05-15	1993-11-16	The Salk Institute For Biological Studies	GRF analogs XI
US5371070A (en) *	1992-11-09	1994-12-06	The Salk Institute For Biological Studies	Bicyclic GnRH antagonists and a method for regulating the secretion of gonadotropins
US6008058A (en) *	1993-06-18	1999-12-28	University Of Louisville	Cyclic peptide mixtures via side chain or backbone attachment and solid phase synthesis
US5780220A (en) *	1994-05-19	1998-07-14	Trustees Of The University Of Pennsylvania	Methods and compositions for inhibiting HIV replication
US5639598A (en) *	1994-05-19	1997-06-17	The Trustees Of The University Of Pennsylvania	Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions
US5942489A (en) *	1996-05-03	1999-08-24	The Administrators Of The Tulane Educational Fund	HGH-RH(1-29)NH2 analogues having antagonistic activity
AU769157B2 (en) *	1999-06-23	2004-01-15	Wistar Institute Of Anatomy And Biology, The	Novel pyrrhocoricin-derived peptides, and methods of use thereof
US7015309B1 (en)	1999-06-23	2006-03-21	The Wistar Institute Of Anatomy And Biology	Pyrrhocoricin-derived peptides, and methods of use thereof
DK2118123T3 (da)	2007-01-31	2016-01-25	Dana Farber Cancer Inst Inc	Stabiliserede p53-peptider og anvendelser deraf
US8592377B2 (en)	2007-03-28	2013-11-26	President And Fellows Of Harvard College	Stitched polypeptides
ES2711526T3 (es)	2010-08-13	2019-05-06	Aileron Therapeutics Inc	Macrociclos peptidomiméticos
AU2011348220B2 (en)	2010-12-22	2017-09-07	The Salk Institute For Biological Studies	Cyclic CRF antagonist peptides
TW201806968A (zh)	2011-10-18	2018-03-01	艾利倫治療公司	擬肽巨環化合物
EP2819688A4 (en)	2012-02-15	2015-10-28	Aileron Therapeutics Inc	TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES
BR112014020103A2 (pt)	2012-02-15	2018-10-09	Aileron Therapeutics, Inc.	macrociclos peptidomiméticos
WO2014071241A1 (en)	2012-11-01	2014-05-08	Aileron Therapeutics, Inc.	Disubstituted amino acids and methods of preparation and use thereof
EP3197478A4 (en)	2014-09-24	2018-05-30	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
WO2016154058A1 (en)	2015-03-20	2016-09-29	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
WO2025128794A1 (en)	2023-12-15	2025-06-19	Neurocrine Biosciences, Inc.	Fatty acid conjugated cyclic peptides

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4563352A (en) *	1982-10-04	1986-01-07	The Salk Institute For Biological Studies	Human pancreatic GRF
US4595676A (en) *	1983-04-26	1986-06-17	The Salk Institute For Biological Studies	Rat hypothalamic GRF
US4518586A (en) *	1983-01-13	1985-05-21	The Salk Institute For Biological Studies	GRF Analogs III
US4626523A (en) *	1983-09-13	1986-12-02	The Salk Institute For Biological Studies	GRF analogs II
US4528190A (en) *	1983-10-25	1985-07-09	The Salk Institute For Biological Studies	GRF Analogs IV
US4661472A (en) *	1985-05-09	1987-04-28	The Salk Institute For Biological Studies	GnRH antagonists IX
US4734399A (en) *	1985-08-06	1988-03-29	Hoffmann-La Roche Inc.	Growth hormone releasing factor analogs
US4689318A (en) *	1985-08-29	1987-08-25	The Salk Institute For Biological Studies	GRF analogs
IL84758A (en) *	1987-01-13	1992-03-29	Salk Inst For Biological Studi	Peptides stimulating the release of pituitary growth hormone in fish and amphibians,and pharmaceutical compositions containing them
US4784987A (en) *	1987-01-13	1988-11-15	The Salk Institute For Biological Studies	GRF analogs VI
EP0307860B1 (en) *	1987-09-18	1994-06-08	F. Hoffmann-La Roche Ag	Cyclic GRF-analogs

1988
- 1988-07-22 US US07/223,277 patent/US5043322A/en not_active Expired - Lifetime
1989
- 1989-06-27 IL IL90766A patent/IL90766A0/xx not_active IP Right Cessation
- 1989-07-03 ZA ZA895050A patent/ZA895050B/xx unknown
- 1989-07-13 EP EP89307089A patent/EP0352014B1/en not_active Expired - Lifetime
- 1989-07-13 AT AT89307089T patent/ATE103609T1/de not_active IP Right Cessation
- 1989-07-13 ES ES89307089T patent/ES2055792T3/es not_active Expired - Lifetime
- 1989-07-13 DE DE68914205T patent/DE68914205T2/de not_active Expired - Fee Related
- 1989-07-18 DK DK355889A patent/DK355889A/da not_active Application Discontinuation
- 1989-07-20 NO NO89892970A patent/NO892970L/no unknown
- 1989-07-21 FI FI893532A patent/FI91074C/fi not_active IP Right Cessation
- 1989-07-21 IE IE892378A patent/IE892378L/xx unknown
- 1989-07-21 KR KR1019890010373A patent/KR0138907B1/ko not_active Expired - Fee Related
- 1989-07-24 JP JP1191231A patent/JP2739910B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR0138907B1 (ko)	1998-04-30
FI893532L (fi)	1990-01-23
JPH0269499A (ja)	1990-03-08
FI893532A0 (fi)	1989-07-21
IL90766A0 (en)	1990-01-18
US5043322A (en)	1991-08-27
DE68914205D1 (de)	1994-05-05
DE68914205T2 (de)	1994-07-07
EP0352014A3 (en)	1991-07-03
EP0352014B1 (en)	1994-03-30
IE892378L (en)	1990-01-22
EP0352014A2 (en)	1990-01-24
ES2055792T3 (es)	1994-09-01
JP2739910B2 (ja)	1998-04-15
ATE103609T1 (de)	1994-04-15
NO892970D0 (no)	1989-07-20
FI91074B (fi)	1994-01-31
FI91074C (fi)	1994-05-10
ZA895050B (en)	1990-04-25
KR910002900A (ko)	1991-02-26
DK355889A (da)	1990-01-23
NO892970L (no)	1990-01-23

Legal Events

Date	Code	Title	Description
1996-03-25	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
EG17394A (en)	1992-12-30	G r f analogs iv
ES8600217A1 (es)	1985-10-01	Un procedimiento para producir peptidos que influyen en la funcion de la glandula pituitaria
DK355889D0 (da)	1989-07-18	Syntetisk peptid og farmaceutisk middel indeholdende peptidet
ES2001274A6 (es)	1988-05-01	Un metodo para preparar peptidos que tienen influencia sobre la funcion de la glandula pituitaria en seres humanos y otros animales
ES8506263A1 (es)	1985-07-01	Un procedimiento para preparar peptidos analogos del factor de liberacion de la hormona del crecimiento de tumor pancreatico humano
ES2085350T3 (es)	1996-06-01	Analogos viia del factor de liberacion de la hormona de crecimiento.
TH1778A (th)	1984-09-03	สารคล้ายคลึง จี อาร์ เอฟ (grf)