DK3575284T3 - Phenyldifluormethyl-substitueret prolinamidforbindelse - Google Patents
Phenyldifluormethyl-substitueret prolinamidforbindelse Download PDFInfo
- Publication number
- DK3575284T3 DK3575284T3 DK18744079.7T DK18744079T DK3575284T3 DK 3575284 T3 DK3575284 T3 DK 3575284T3 DK 18744079 T DK18744079 T DK 18744079T DK 3575284 T3 DK3575284 T3 DK 3575284T3
- Authority
- DK
- Denmark
- Prior art keywords
- phenyldifluoromethyl
- prolinamide compound
- substituted prolinamide
- substituted
- compound
- Prior art date
Links
- -1 PROLINAMIDE COMPOUND Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017010321 | 2017-01-24 | ||
| PCT/JP2018/001927 WO2018139438A1 (ja) | 2017-01-24 | 2018-01-23 | フェニルジフルオロメチル置換プロリンアミド化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3575284T3 true DK3575284T3 (da) | 2021-10-18 |
Family
ID=62979051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18744079.7T DK3575284T3 (da) | 2017-01-24 | 2018-01-23 | Phenyldifluormethyl-substitueret prolinamidforbindelse |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US10322997B2 (da) |
| EP (1) | EP3575284B1 (da) |
| JP (1) | JP7001068B2 (da) |
| KR (1) | KR102553613B1 (da) |
| CN (2) | CN110248925B (da) |
| AR (1) | AR110767A1 (da) |
| AU (1) | AU2018211735B2 (da) |
| BR (1) | BR112019014788A2 (da) |
| CA (1) | CA3050224A1 (da) |
| CO (1) | CO2019009090A2 (da) |
| CY (1) | CY1124906T1 (da) |
| DK (1) | DK3575284T3 (da) |
| ES (1) | ES2892400T3 (da) |
| HR (1) | HRP20211613T1 (da) |
| HU (1) | HUE056920T2 (da) |
| IL (1) | IL268060B (da) |
| JO (1) | JOP20190181B1 (da) |
| LT (1) | LT3575284T (da) |
| MA (1) | MA47380A (da) |
| MX (1) | MX379651B (da) |
| MY (1) | MY195587A (da) |
| PH (1) | PH12019501645A1 (da) |
| PL (1) | PL3575284T3 (da) |
| PT (1) | PT3575284T (da) |
| RS (1) | RS62477B1 (da) |
| SG (1) | SG11201906777TA (da) |
| SI (1) | SI3575284T1 (da) |
| TW (1) | TWI764976B (da) |
| UA (1) | UA124036C2 (da) |
| WO (1) | WO2018139438A1 (da) |
| ZA (1) | ZA201904741B (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7375134B2 (en) * | 2002-03-05 | 2008-05-20 | Axys Pharmaceuticals, Inc. | Cathepsin cysteine protease inhibitors |
| JP2010121918A (ja) | 2008-11-17 | 2010-06-03 | Hiroyoshi Asada | 鍋等の取っ手部分の焼き焦げ防止具。 |
| SI2421826T1 (sl) * | 2009-04-20 | 2014-02-28 | F. Hoffmann-La Roche Ag | Derivati prolina kot inhibitorji katepsina |
| US7893099B2 (en) * | 2009-06-11 | 2011-02-22 | Hoffman-La Roche Inc. | Cyclopentane derivatives |
| JP2012059507A (ja) | 2010-09-08 | 2012-03-22 | Panasonic Corp | 基板間接続コネクタ構造 |
| US8524710B2 (en) | 2010-11-05 | 2013-09-03 | Hoffmann-La Roche Inc. | Pyrrolidine derivatives |
| CN103930400B (zh) * | 2011-11-11 | 2016-04-20 | 霍夫曼-拉罗奇有限公司 | 制备1-酰基-4-苯基磺酰基脯氨酰胺衍生物的方法及中间体 |
| CA2859928A1 (en) * | 2012-02-17 | 2013-08-22 | F. Hoffmann-La Roche Ag | Novel pyrrolidine derivatives |
| TW201412728A (zh) | 2012-08-21 | 2014-04-01 | Hoffmann La Roche | 新穎吡啶衍生物 |
| WO2015051479A1 (en) * | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
| WO2015054089A1 (en) * | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
| DK3419970T3 (da) | 2016-02-26 | 2020-03-02 | H Hoffmann La Roche Ag | Hidtil ukendte pyridinderivater |
-
2018
- 2018-01-23 MA MA047380A patent/MA47380A/fr unknown
- 2018-01-23 PL PL18744079T patent/PL3575284T3/pl unknown
- 2018-01-23 SI SI201830429T patent/SI3575284T1/sl unknown
- 2018-01-23 HU HUE18744079A patent/HUE056920T2/hu unknown
- 2018-01-23 EP EP18744079.7A patent/EP3575284B1/en active Active
- 2018-01-23 JP JP2018564576A patent/JP7001068B2/ja not_active Expired - Fee Related
- 2018-01-23 CN CN201880008062.3A patent/CN110248925B/zh not_active Expired - Fee Related
- 2018-01-23 MY MYPI2019004186A patent/MY195587A/en unknown
- 2018-01-23 ES ES18744079T patent/ES2892400T3/es active Active
- 2018-01-23 LT LTEPPCT/JP2018/001927T patent/LT3575284T/lt unknown
- 2018-01-23 AR ARP180100143A patent/AR110767A1/es not_active Application Discontinuation
- 2018-01-23 SG SG11201906777TA patent/SG11201906777TA/en unknown
- 2018-01-23 MX MX2019008756A patent/MX379651B/es unknown
- 2018-01-23 PT PT18744079T patent/PT3575284T/pt unknown
- 2018-01-23 RS RS20211299A patent/RS62477B1/sr unknown
- 2018-01-23 HR HRP20211613TT patent/HRP20211613T1/hr unknown
- 2018-01-23 JO JOP/2019/0181A patent/JOP20190181B1/ar active
- 2018-01-23 WO PCT/JP2018/001927 patent/WO2018139438A1/ja not_active Ceased
- 2018-01-23 KR KR1020197021643A patent/KR102553613B1/ko active Active
- 2018-01-23 CN CN202010529596.XA patent/CN111574422B/zh not_active Expired - Fee Related
- 2018-01-23 UA UAA201908429A patent/UA124036C2/uk unknown
- 2018-01-23 CA CA3050224A patent/CA3050224A1/en active Pending
- 2018-01-23 TW TW107102307A patent/TWI764976B/zh not_active IP Right Cessation
- 2018-01-23 BR BR112019014788-8A patent/BR112019014788A2/pt not_active Application Discontinuation
- 2018-01-23 AU AU2018211735A patent/AU2018211735B2/en not_active Ceased
- 2018-01-23 DK DK18744079.7T patent/DK3575284T3/da active
- 2018-11-05 US US16/180,862 patent/US10322997B2/en active Active
-
2019
- 2019-04-25 US US16/394,571 patent/US10532979B2/en active Active
- 2019-07-15 PH PH12019501645A patent/PH12019501645A1/en unknown
- 2019-07-15 IL IL268060A patent/IL268060B/en unknown
- 2019-07-18 ZA ZA2019/04741A patent/ZA201904741B/en unknown
- 2019-08-22 CO CONC2019/0009090A patent/CO2019009090A2/es unknown
-
2021
- 2021-10-26 CY CY20211100928T patent/CY1124906T1/el unknown
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